Research in the Dermatology Department


The Department of Dermatology has a long history of cutting-edge and compelling research. A large and diverse patient population make the medical center an ideal place for clinical research trials, and the active laboratories focus on many of the core issues in the basic science of dermatology.

The basic science research at SUNY Downstate focuses on the effects of physical and chemical stimuli on the skin. The main laboratory, spearheaded by Dr. Wei-Li Lee, has developed many in vitro models that are used to understand how UV radiation, microbial organisms, and chemical irritants interact with the skin. In addition, the laboratory studies the skin's response to infection and the effects of alternative and natural ingredients in the treatment of skin conditions.

Lab Stuff

Dr. Jared Jagdeo’s research lab focuses on the use of phototherapy, neurobiomodulators, and antioxidants to improve skin fibrosis (scarring) and cancer. His laboratory team has pioneered the use of high fluence light-emitting diode red light (LED-RL) to modulate the activity of skin cells. Dr. Jagdeo is actively performing clinical trials to assess the safety and efficacy of LED-RL to treat patients with skin fibrosis.

Other basic scientists at SUNY Downstate, including Dr. Neil Brody, have focused their research on tumor immunology, the role of antioxidants on cell survival, the effects of visible light on fibroblast function, and the psychological benefits of neuromodulators. Work is currently being done on the effects of polyphenols on acne pathogenesis.