Educational Resources

Assessing Pain and Distress

• ACLAM Position Statement on Assessing Pain & Distress
• Guidelines for the Assessment and Management of Pain in Rodents and Rabbits
• Recognition and Alleviation of Pain in Laboratory Animals
• Study Ongoing and Spontaneous Pain in Rodents
• Tests and Models of Nociception and Pain in Rodents

Non-Surgical Procedures

Blood Collection

• Blood Collection Parameters – See "Sample Collection: Blood" Section
• NC3Rs Blood Sampling by Species

Substance Administration

• Administration of Substances to Laboratory Animals: Equipment Considerations, Vehicle Selection, and Solute Preparation
• Administration of Substances to Laboratory Animals: Routes of Administration and Factors to Consider
• Demonstrating rodent handling and administration of substances
• Dosing Parameters – routes of administration, volumes, associated needle gauges: See "Substance Administration" Section
• Procedures With Care - Instructional Videos & Narratives
  • Handling and Restraint of the Animal
  • IM Injection in the Rat
  • IP Injection of the Mouse
  • IP Injection of the Rat
  • IV Injection in the Mouse
  • IV Injection in the Rat
  • Oral Gavage in the Mouse
  • Oral Gavage in the Rat
  • Subcutaneous Injection in the Mouse
  • Subcutaneous Injection in the Rat

Surgical Procedures

• ACLAM Position Statement on Medical Records for Animals Used in Research, Teaching, and Testing
• ACLAM Position Statement on Rodent Surgery
• FLAIRE Learning, Laboratory Animal Anaesthesia for Minor Procedures.
• Principles of Rodent Surgery
  • Aseptic Rodent Surgery -YouTube Videos & Other Instructional Technique Documents
  • Aseptic Technique in Rodent Surgery - Procedures With Care
  • JoVE Video - Principles of Rodent Surgery
  • JoVE Article – Principles of Rodent Surgery
  • Proper Techniques in Aseptic Rodent Surgery - NIH
• WHO Guidelines on Hand Hygiene in Health Care

Biostatistical Consultation at Downstate

The Office of the SVPR provides biostatistical support to Downstate faculty, based on the research project and methodology. Our office strongly recommends consulting with a biostatistician as early as possible, preferably at the conception stage of the project, and not after data collection. To request a consult, please complete the intake form.