Educational Resources

Assessing Pain and Distress

• ACLAM Position Statement on Assessing Pain & Distress
• Guidelines for the Assessment and Management of Pain in Rodents and Rabbits
• Recognition and Alleviation of Pain in Laboratory Animals
• Study Ongoing and Spontaneous Pain in Rodents
• Tests and Models of Nociception and Pain in Rodents

Non-Surgical Procedures

Blood Collection

• Blood Collection Parameters – See "Sample Collection: Blood" Section
• NC3Rs Blood Sampling by Species

Substance Administration

• Administration of Substances to Laboratory Animals: Equipment Considerations, Vehicle Selection, and Solute Preparation
• Administration of Substances to Laboratory Animals: Routes of Administration and Factors to Consider
• Demonstrating rodent handling and administration of substances
• Dosing Parameters – routes of administration, volumes, associated needle gauges: See "Substance Administration" Section
• Procedures With Care - Instructional Videos & Narratives
  • Handling and Restraint of the Animal
  • IM Injection in the Rat
  • IP Injection of the Mouse
  • IP Injection of the Rat
  • IV Injection in the Mouse
  • IV Injection in the Rat
  • Oral Gavage in the Mouse
  • Oral Gavage in the Rat
  • Subcutaneous Injection in the Mouse
  • Subcutaneous Injection in the Rat

Surgical Procedures

• ACLAM Position Statement on Medical Records for Animals Used in Research, Teaching, and Testing
• ACLAM Position Statement on Rodent Surgery
• FLAIRE Learning, Laboratory Animal Anaesthesia for Minor Procedures.
• Principles of Rodent Surgery
  • Aseptic Rodent Surgery -YouTube Videos & Other Instructional Technique Documents
  • Aseptic Technique in Rodent Surgery - Procedures With Care
  • JoVE Video - Principles of Rodent Surgery
  • JoVE Article – Principles of Rodent Surgery
  • Proper Techniques in Aseptic Rodent Surgery - NIH
• WHO Guidelines on Hand Hygiene in Health Care