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SUNY Downstate Health Sciences University

Office of Development & Philanthropy

The Doctors Alan and Adele Josephson Memorial Fund

The Drs. Alan and Adele Josephson Memorial Lectureship

The Division of Allergy & Immunology,
Department of Medicine


The 10th Annual Josephson Lectureship

May 8, 2014
SUNY Downstate Medical Center

Jeffrey V. Ravetch, M.D., PhD
Theresa and Eugene M. Lang Professor
Leonard Wagner Laboratory of Molecular Genetic & Immunology
Rockefeller University

Lecture 10 – Spring, 2014:

The antibody Fc domain: a determinant of structure and functional diversity in health and disease

Jeffrey V. Ravetch, M.D., PhD

Jeffrey V. Ravetch, M.D., PhD

Dr. Ravetch graduated from Yale University in 1973 and received his Ph.D. in 1978 from The Rockefeller University, where he studied under Norton Zinder and Peter Model. He received his M.D. from Cornell University Medical College in 1979 and completed his postdoctoral research at the National Institutes of Health with Philip Leder. In 1982 Dr. Ravetch joined the faculty of Memorial Sloan-Kettering Cancer Center and in 1984 also became a guest investigator in Rockefeller's Laboratory of Cellular Physiology and Immunology. He was appointed professor at Rockefeller in 1996 and named Theresa and Eugene M. Lang Professor in 1997. Dr. Ravetch received the Canada Gairdner International Award and the Sanofi-Pasteur Award in 2012, the Coley Award from the Cancer Research Institute in 2007, the American Association of Immunologists-Huang Foundation Meritorious Career Award in 2005, the Lee C. Howley Sr. Prize for Arthritis Research in 2004 and the Burroughs Wellcome Fund Award in Molecular Parasitology in 1986. He is a fellow of the American Academy of Arts and Sciences and the American Association for the Advancement of Science and a member of the National Academy of Sciences and the Institute of Medicine. (Source: The Rockefeller University)


Past Lectures

Lecture 9 – Spring, 2013:

Charlotte Cunningham-Rundles, M.D., PhD
Professor of Medicine
Departments of Medicine and Pediatrics
Mount Sinai School of Medicine

What's New in Common Variable Immune Deficiency


Lecture 8 – Spring, 2012:

William E. Paul, M.D.
National Institutes of Health Distinguished Investigator
Chief, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases

Cytokines and CD4 T Cells; Dance Partners at the Immunology Ball


Lecture 7 – Spring, 2011:

Robert Greenwald, M.D.
Master, American College of Rheumatology
Former Chief, Rheumatology Division, Long Island Jewish Medical Center
Professor of Medicine, Albert Einstein College of Medicine
Adjunct Professor of Oral Biology and Pathology, School of Dental Medicine, SUNY Stony Brook

Why I take a matrix metalloproteinase inhibitor every morning


Lecture 6 — Spring, 2010:

Vincent K. Tuohy, PhD
Professor, Lerner College of Medicine
Lerner Research Institute, Department of Immunology, Cleveland Clinic
Endowed Chair in Breast Cancer Research

Prophylactic Breast Cancer Vaccination


Lecture 5 — Spring, 2009

J. Harold Helderman, M.D., FACP
Professor of Medicine, Microbiology and Immunology
Medical Director, Vanderbilt Transplant Center
Chief, Renal Transplant Medicine
Vanderbilt University School of Medicine

Neo receptors, markers of lymphocyte activation: lessons from study of the insulin receptor


Lecture 4 — Spring, 2008:

Allen Kaplan, M.D.
Professor of Medicine
Division of Pulmonary, Critical Care, Allergy and Immunology
Medical University of South Cariolina

Bradykinin and its role in angioedema


Lecture 3 — Spring, 2007:

Thomas Platts-Mills, M.D., PhD
Professor of Medicine
Chief, Division of Allergy and Clinical Immunology
University of Virginia

Understanding the asthma epidemic


Lecture 2 — Spring, 2006:

Manikkam Suthanthiran, M.D.
Stanton Griffis Distinguished Professor of Medicine
Chief, Nephrology and Transplantation Medicine
New York Presbyterian Hospital - Weill Cornell Medical Center

Organ Transplantation: Reaping the Rewards of Biomedical Research


Lecture 1 — Spring, 2005:

Phillip D. Greenberg, M.D.
Professor of Medicine & Immunology
University of Washington at Fred Hutchinson Cancer Research Center

Cellular and molecular engineering of T cell responses to tumors: Making T cells a treatment for the masses