Sherene Sharath, PhD, MPH

Sherene Sharath, PhD, MPH

Assistant Professor of Surgery
Director of Clinical and Health Services Research
Department of Surgery

Dr. Sharath is an epidemiologist with a special focus in biostatistics. She is Director of Clinical and Health Services Research for the Department of Surgery. Her responsibilities center around the research education of trainees and development of the department’s research program – both of which are largely achieved through the Department’s iNSPIRe Initiative. She is also the national clinical trial coordinator for the federally-funded Department of Veterans Affairs TOP Trial, a multi-center, randomized controlled trial examining the effects of permissive anemia on postoperative adverse events after major operations in high cardiac risk patients. Dr. Sharath holds a secondary appointment as Assistant Professor in the Department of Epidemiology and Biostatistics at the School of Public Health.

Dr. Sharath received her PhD in Epidemiology, with a minor in Biostatistics, from the University of Texas School of Public Health in Houston, TX. She received her MPH in Epidemiology and BS in Microbiology from Texas A&M University in College Station, TX.

Dr. Sharath’s research is focused on integrating scientifically sound study designs with uniform implementation to ensure validity and precision. She pursues translational research that highlights effective multi-disciplinary collaboration in answering novel, practice-changing questions.  Most notably, she has extensive expertise in the management and analysis of big datasets, typically consisting of several millions of observations. Dr. Sharath’s work covers three specific areas:

  • Behavioral predictors of nonoperative disease management strategies
  • Systematic, cohort-specific assessment of postoperative short- and long-term risks
  • Identifying and assessing specific reasons for treatment disparities in vascular diseases
  • Kougias P, Sharath SE, Zamani N, Brunicardi FC, Berger DH, Wilson MA (2022). Timing of a major operative intervention after a positive COVID-19 test affects postoperative mortality. Results from a nationwide, procedure matched analysis. Annals of Surgery, in press and available online. PMID: 35837893

  • Sharath SE, Kougias P, Barshes NR (2021). Health expectations, risk tolerance, and walking in peripheral artery disease-related claudication. Journal of Social, Behavioral, and Health Sciences, 15: 363-370.

  • Sharath SE, Zamani N, DeSantis S, Kougias P (2021). Treatment of early deep wound infections: a meta-analysis and survey. Annals of Vascular Surgery, 74:356-366. PMID: 33549780

  • Zamani N, Sharath SE, Browder RC, Barshes NR, Braun JD, Mills JL Sr., Kougias P, Younes HK (2020). Outcomes after endovascular stent placement for long-segment superficial femoral artery lesions. Annals of Vascular Surgery, 71:298-307. PMID: 32891746

  • Barshes NR, Uribe-Gomez A, Sharath SE, Mills JL Sr., Rogers SO Jr. (2020). Leg amputations among Texans Remote from Experienced Surgical Care. Journal of Surgical Research, 250: 232- 238. PMID: 31870563

  • Zamani N, Sharath SE, Barshes NR, Braun JD, Kougias P (2020). Long-term outcomes of lower extremity graft preservation using antibiotic beads in patients with early deep wound infections after major arterial reconstructions. Journal of Vascular Surgery, 71(4): 1315-1321. PMID: 31519515

  • Kougias P, Sharath S, Mi Z, Biswas K, Mills JL (2019). Effect of postoperative permissive anemia and cardiovascular risk status on outcomes after major general and vascular surgery operative interventions. Annals of Surgery, 270 (4): 602 611. PMID: 31478978

  • Sharath SE, Lee MJ, Kougias P, Taylor WC, Zamani N, Barshes NR (2019). Delayed gratification and adherence to exercise among patients with claudication. Vascular Medicine, 24(6): 519-527. PMID: 31409207

  • Cao J, Sharath SE, Zamani N, Barshes NR (2019). Health care resource distribution of Texas counties with high rates of leg amputations. Journal of Surgical Research, 243: 213 219. PMID: 31195350

  • Kougias P, Tiwari V, Sharath SE, Garcia A, Pathak A, Chen M, Ramsey D, Barshes NR, Berger DH (2019). A Statistical Model-Driven Surgical Case Scheduling System Improves Multiple Measures of Operative Suite Efficiency: Findings from a Single-Center, Randomized Controlled Trial. Annals of Surgery, 270(6): 1000-1004. PMID: 29697450

  • Sharath SE, Lee MJ, Kougias P, Taylor WC, Zamani N, Barshes NR (2018). Successful smoking cessation associated with walking behavior in patients with claudication. Annals of Vascular Surgery, 53:287-293. PMID: 30500660

  • Sharath SE, Zamani N, Kougias P, Kim S (2018). Missing data in surgical data sets: a review of pertinent issues and solutions. Journal of Surgical Research, 232: 240-246. PMID: 30463724
    ** Featured on the cover of the publishing journal with accompanying cover illustration.

  • Barshes NR, Sharath S, Zamani N, Smith K, Serag H, Rogers S (2018). Racial and Geographic      Variation in Leg Amputations among Texans. Texas Public Health Journal, 70(3):22-27. PMID: 30873515

  • Zamani N, Sharath SE, Vo E, Awad SS, Kougias P, Barshes NR (2018). A Multi-Component Strategy to Decrease Wound Complications after Open Infra-Inguinal Revascularization. Surgical Infections, 19(1):87-94. PMID: 29303688

  • Kougias P, Sharath S, Barshes NR, Chen M, Mills JL (2017). Effect of postoperative anemia and baseline cardiac risk on serious adverse outcomes after major vascular interventions. Journal of Vascular Surgery, 66(6):1836-1843. PMID: 28947229

  • Sharath S, Kougias P, Barshes NR (2017). The influence of pain-related beliefs on physical activity and health attitudes in patients with claudication: A pilot study. Vascular Medicine, 22(5): 378-384. PMID: 28545320
    ** Featured in editorial of publishing journal: Schorr, E.N., Mays, R.J., (2017). Patient perspectives on claudication: An opportunity to improve the adoption and adherence of exercise therapy. Vascular Medicine, 22(5): 385-6.

  • Sharath S, Kougias P, Pisimisis G, Barshes NR (2016). The impact of clinical, psychological, behavioral, social, and environmental factors on self-perceived symptom severity in a male cohort with intermittent claudication. Journal of Vascular Surgery, 63(5), 1296-1304. PMID: 26821592

  • Sharath S, Henson H, Flynn S, Pisimisis G, Kougias P, Barshes NR (2015). Ambulation and independence among Veterans with non-traumatic bilateral lower-limb loss. Journal of Rehabilitation Research and Development, 52(7), 851-858. PMID: 26745753

  • Kougias P, Sharath S, Barshes NR, Lowery B, Garcia A, Pak T, Bechara CF, Pisimisis G (2014). Impact of cumulative intravascular contrast exposure on renal function in patients with occlusive and aneurysmal vascular disease. Journal of Vascular Surgery, 59(6), 1644-1650. PMID: 24560864


    Sharath S., complete bibliography

Department Links

Department of Surgery