Samantha Mazzeo, DO

Samantha Mazzeo, DO, is a non-operative sports medicine physician with training in emergency medicine, internal medicine, and sports medicine. Her clinical background includes acute care, primary care, hospitalist medicine, and the non-operative management of musculoskeletal conditions and athletic injuries. She is board certified in internal medicine.

Dr. Mazzeo earned her Doctor of Osteopathic Medicine from the New York Institute of Technology College of Osteopathic Medicine. She completed a combined emergency medicine and internal medicine residency at SUNY Downstate Health Sciences University and Kings County Hospital Center, where she served as chief resident, and pursued sports medicine fellowship training at The Mount Sinai Hospital.

Her experience includes team physician work with USA Fencing and sports coverage for high school, collegiate, national, and international events. She is committed to compassionate, evidence-based care tailored to each patient’s lifestyle and goals, including injury treatment, rehabilitation coordination, and return-to-play guidance. She also has a strong interest in medical education and improving musculoskeletal education for emergency medicine residents.

• Sports Medicine Fellowship, 2025–2026
  The Mount Sinai Hospital, Department of Rehabilitation and Human Performance, New York, NY
• Combined Emergency Medicine and Internal Medicine Residency, 2020–2025
  SUNY Downstate Health Sciences University / Kings County Hospital Center, Brooklyn, NY
  Chief Resident, 2024–2025
• Doctor of Osteopathic Medicine, 2020
  New York Institute of Technology College of Osteopathic Medicine, Old Westbury, NY
• Bachelor of Science in Biology, 2014
  Fairfield University, Fairfield, CT
  Minor in Behavioral Neuroscience; magna cum laude

Board Certification

American Board of Internal Medicine, August 2025

• Non-operative treatment of musculoskeletal conditions and sports injuries
• Non-operative fracture management, including acute evaluation, reduction, splinting, and casting
• Rehabilitation coordination and return-to-play decisions
• Point-of-care ultrasound and bedside and minimally invasive procedures
• Care of active individuals and athletes, including collegiate and Olympic-level athletics
• Women’s health, performance evaluation and optimization, and nutrition and dietary guidance
• Wilderness medicine

Peer-Reviewed Publications

• Mazzeo S, Silverberg C, Oommen T, et al. Effects of Osteopathic Manipulative Treatment on Sleep Quality in Student Athletes After Concussion: A Pilot Study. Journal of the American Osteopathic Association. 2020. doi: 10.7556/jaoa.2020.100.
• Gerry SP, Brodeur LK, DeCaprio M, Khursigara AJ, Mazzeo S, Neubauer DL. Jaw muscle activation patterns of several Batoids. Environmental Biology of Fishes. 2019;102:1193–1200. doi: 10.1007/s10641-019-00901-7.

Selected Honors

• Toxicology Award for Outstanding Contributions to the Toxicology Department, SUNY Downstate / Kings County Hospital Center, Class of 2025
• Student Education Award for Outstanding Contributions to Student Education, SUNY Downstate / Kings County Hospital Center, Class of 2025
• Emergency Medicine Resident of the Year, SUNY Downstate / Kings County Hospital Center, 2023