Subodh J. Saggi, MD, MPH, FACP, FASN

Dr. Subodh J. Saggi MD, MPH is Professor of Medicine, Program Director of Nephrology, Director of Parkside Ambulatory Dialysis and Director of Extracorporeal therapies at SUNY Downstate Health Sciences University, Brooklyn. Dr. Saggi serves as the key individual for managing most cases of genetic disorders affecting the kidneys, chief amongst them being Autosomal Dominant Polycystic Kidney (ADPKD) disease. Based on his work for these patients Polycystic Kidney Foundation designated SUNY Downstate a Center of Excellence partner clinic for this disease.

Dr. Saggi has had extensive experience in basic sciences studying the molecular mechanisms of Acute Kidney Injury to help understand renal regeneration and progression to Chronic kidney Disease. He has had many years of experience in managing patients with chronic kidney disease preventing their kidneys from failing. He is the Chair of ESRD Network region 2 (New York) for Quality and oversees the Quality of Dialysis Care in several dialysis facilities.

Dr. Saggi is involved in teaching medical students, residents and fellows in diagnosis and managing patients with kidney diseases. He conducts and oversees several clinical trials for Renal Division. He is the principal investigator for clinical trials involving Focal Segmental Glomerulosclerosis which affects predominantly African American population, clinical trials in Lupus Nephritis, clinical trials in ADPKD, and has done several clinical trials in dialysis patients. He has been published extensively for the work he has done. He is Board Certified in Internal medicine and Nephrology and currently an item task writer for ABIIM Board exam Nephrology section.

Education

• Undergraduate: Elphinstone College, Bombay University
• Advanced Degree: Columbia University, MPH
• Medical School: T. N. Medical College, Bombay University, India
• Internship: Mount Sinai School of Medicine
• Residency: Mount Sinai School of Medicine
• Fellowship: Mount Sinai School of Medicine

Research Interests

• Randomized Clinical Trials in Nephrotic Syndromes
• Focal Segmental Glomerulosclerosis, Lupus, and Trials in Dialysis and Autosomal Dominant Polycystic Kidney Disease's, Glomerulonephritis and several Kidney Diseases

• Ranganathan N, Pechenyak B, Vyas U,Ranganathan P, Weinberg A, Liang P, Mallappallil MC, Norin AL, Friedman EA, Saggi SJ: Randomized Controlled Trial of Strain-Specific Probiotic Formulation (Renadyl) in Dialysis Patients: Biomed Research International ID 568571: 2014: 1-9. 2014: 568571. doi: 10.1155/2014/568571. Epub 2014 Jul 24. PMID: 25147806.
• Cukor D, Ver Halen N, Asher DR, Coplan JD, Weedon J, Wyka EK, Saggi SJ, Kimmel PL: PsychosocialIntervention Improves Depression, Quality of Life, and Fluid Adherence in Hemodialysis: JASN: 2014: 25:196-206. doi:10.1681/ASN.2012111134. Epub 2013 Oct 10. PMID: 24115478.
• Ranganathan N, Pechenyak B, Vyas U,Ranganathan P, DeLoach S, Falkner B, Weinberg A, Saggi SJ, Friedman EA:Dose Escalation, Safety and impact of a strain specific Probiotic (RenadylTM) on Stages 3 and 4 Chronic Kidney Disease Patients: Nephrology and Therapeutics: 2013:3:3:1-9.
• Saggi SJ, Salifu M:Sluggish Left Atria Predecessor to Stroke in CKD: Cause or Effect: Cardiology 2013; 124:25-27. doi: 10.1159/000346031. Epub 2013Jan 3. PMID: 23295387.
• Pai AB, Cardone KE, Manley HJ,St Peter WL, Shaffer R, Somers M, Mehrotra R: Dialysis Advisory Group of American Society of Nephrology Collaborator Saggi SJ: Medication reconciliation and therapy management in dialysis-dependent patients: need for a systematic approach: Clin J Am Soc Nephrol. 2013 Nov; 8(11):1988-99. doi:10.2215/CJN.01420213. Epub 2013 Aug 29. PMID: 23990162.
• Young BA, Chan C, Blagg C, Lockridge R, Golper T, Finkelstein F, Shaffer R, Mehrotra R; ASN Dialysis Advisory Group of the American Society of Nephrology Collaborator Saggi SJ: How to overcome barriers and establish a successful home HD program: Clin J Am Soc Nephrol. 2012 Dec; 7(12):2023-32. doi: .2215/CJN.07080712.Epub 2012 Oct 4. PMID: 23037981.
• Cukor D, Fruchter Y, Halen verN, Naidoo S, Patel A, Saggi SJ: A preliminary Investigation of Depression and Kidney Functioning in Patients with Chronic Kidney Disease: Nephron Clin Pract: 2012:122:139-145. doi:10.1159/000349940. Epub 2013 Jun 1. PMID: 23736810.
• Watnick S, Weiner DE, Shaffer R, Inrig J, Moe S, Mehrotra R; Dialysis Advisory Group of the American Society of Nephrology Collaborator Saggi SJ: Comparing mandated health care reforms: the Affordable Care Act, accountable care organizations, and the Medicare ESRD program: Clin J Am Soc Nephrol. 2012 Sep; 7(9):1535-43. Epub 2012 May 24. PMID: 22626961.
• Vanholder R, Davenport A,Hannedouche T, Kooman J, Kribben A, Lameire N, Lonnemann G, Magner P, Mendelssohn D, Saggi SJ, Shaffer RN, Moe SM, Van Biesen W, van der Sande F, Mehrotra R; Reimbursement of Dialysis: A Comparison of Seven Countries. J Am Soc Nephrol: Aug 1, 2012 23: 1291-1298. Epub 2012 Jun 7. PMID: 22677554.
• Saggi SJ, Allon M,Bernardini J, Kalantar-Zadeh K, Shaffer R, Mehrotra R.: Considerations in the optimal preparation of patients for dialysis: Nat Rev Nephrol: Nature Reviews Nephrology 8, 381-389 (July 2012). doi:10.1038/nrneph.2012.66. PMID: 22487703.
• Nickolas TL, Schmidt-Ott KM,Canetta P, Forster C, Singer E, Sise M, Elger A, Maarouf O, Sola-DelValle DA, O'Rourke M, Sherman E, Lee P, Geara A, Imus P, Guddati A, Polland A, Rahman W, Elitok S, Malik N, Giglio J, El-Sayegh S, Devarajan P, Hebbar S, Saggi SJ ,Hahn B, Kettritz R, Loft FC, Barasch J: Diagnostic and PrognosticStratification in the Emergency Department Using Urinary Biomarkers of Nephron Damage. A Multicenter Prospective Cohort Study: Journal of American College of Cardiology: 2012:59:3:246-55. doi: 10.1016/j.jacc.2011.10.854. PMID: 22240130.
• Inrig J, Saggi SJ,Weiner D, Shaffer R, Mehrotra R. Bundled Payments for Kidney Care. ASN Kidney News: 2011: Jan: 8-9
• Saggi SJ, Salifu MO.Pre-Clinical Myocardial Metabolic Alterations in Chronic kidney Disease: Cardiology 2010; 116:157-159. doi: 10.1159/000318225. Epub 2010 Jul 9. PMID: 20616548.
• El-Harakeh MA, Barbari A,Stephan A, Saggi S, Kilany H, Barakeh A. A transplanted kidney surviving total vessel occlusion and anuria. Clin Nephrol. 2005 Aug; 64(2):159-62. Clin Nephrol. 2005 Aug; 64(2):159-62. PMID: 16114794.
• Saggi SJ,Andoh TF, Safirstein R, Bennett WM. Cyclosporine Induces renal proto-oncogene RNA message and increased transforming growth factor-prior to renal fibrosis: Modification by calcium channel blockade in the salt replete rat. Nephrology 2004; 9, 58-64. PMID: 15056263.