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Dr. Jared Jagdeo discusses LED technology in The New York Times.
Dr. Andrew Mamalis receives the 2018 Robert F. Furchgott Award for his work on LED-RL for treating scars and skin fibrosis.
Andrew Mamalis, M.D.
Andrew Mamalis is a resident in the Department of Dermatology. He graduated from University of California, Merced with his B.S. in Biological Sciences and then attended University of California, Davis for his M.D. and master’s degrees. He has conducted his research under the mentorship of Dr. Jared Jagdeo. His research focuses on the therapeutic use of visible red LED-generated light and its potential to treat scars and skin fibrosis. His basic science findings demonstrate that red light is capable of downregulating fibroblast proliferation and collagen production through modulation of reactive oxygen species and the TGF-beta pathway. He has also published on the mechanisms underlying these red light induced effects, including investigating the role of mitochondrial modulation and transcriptome changes. Dr. Mamalis is also involved in the study to translate these in vitro findings to a Phase II clinical trial. His other research projects include studies on novel uses of laser therapies and photodynamic therapy in clinical dermatology.