Chella Kamarajan, PhD

Profile

Dr. Chella Kamarajan, PhD, serves as an assistant professor of psychiatry and is affiliated with the Henri Begleiter Neurodynamics Laboratory (HBNL), a world-renowned center for its cutting-edge research on neuroscience and genetics of alcohol/drug addiction. He is a clinical psychologist, neuropsychologist, and neuroscientist by training. Since joining the HBNL in 2002, Dr. Kamarajan has been affiliated with several NIH-funded research projects, including the Collaborative Study on the Genetics of Alcoholism (Current Role: Co-Investigator; PI: Bernice Porjesz), a multi-center consortium that aims to elucidate the role of genetic, neural, and environmental factors and their interactions in the development of alcohol use disorder and other related clinical traits. He is a co-principal investigator (MPI) in an NIH-funded R01 project that aims to understand neurocognitive and genomic factors underlying the risk of developing alcohol use disorder. Dr. Kamarajan has published 120+ peer-reviewed articles (23 first-author papers) on a range of topics, primarily focusing on neuroscience and genetics of addiction. His recent work expands to include novel methods and measures of brain imaging (EEG/ERP/ERO, s/fMRI, fNIRS) and stimulation (rTMS, tDCS) for translational applications. His recent work also focuses on prediction models using machine learning techniques is at the interface between basic science and clinical applications. Currently, his work focuses on predicting brain age using neuroimaging and neurophysiological datasets. He has presented some of the major findings at scientific conferences, including many symposia which he organized. Dr. Kamarajan is actively involved in didactic teaching and mentoring to medical students, psychiatry residents, and fellows. He serves as the chair of research committee in psychiatry to train the residents and fellows during their research rotations. He is also the director of the research elective “Neuroelectric features in addiction” for medical students. He serves on the editorial boards of many scientific journals and has guest-edited several special issues. He is also a prolific reviewer scientific and professional journals (100+ reviews; 20+ journals). Dr. Kamarajan serves as an expert reviewer on the NIH/CSR study sections and other international funding agencies. He has served as an external (international) examiner to adjudicate many doctoral dissertations (n=20+). Dr. Kamarajan is a member of many professional organizations, including the American Psychological Association, the International Organization of Psychophysiology, the Research Society on Alcohol, and the International Neuropsychoanalysis Society. He also serves on several committees, including the College of Medicine Executive Committee, Faculty Wellness Workgroup, Dean’s Council for Education, and the Communication Committee of the SUNY Faculty Senate.

Number of Publications: 122 (as of 2024-04-18)

Number of Citations: 3459 (as of 2024-04-18)

• Paul SE, Baranger DAA, Johnson EC, Jackson JJ, Gorelik AJ, Miller AP, Hatoum AS, Thompson WK, Strube M, Dick DM, Kamarajan C, Kramer JR, Plawecki MH, Chan G, Anokhin AP, Chorlian DB, Kinreich S, Meyers JL, Porjesz B, Edenberg HJ, Agrawal A, Bucholz KK, Bogdan R (in press) Longitudinal Relationships Between Alcohol Milestones and Internalizing, Externalizing, and Executive Function, and Associations with Polygenic Scores. Psychological Medicine.
• Barr P, Neale Z, Chatzinakos C, Schulman J, Mullins N, Zhang J, Chorlian D, Kamarajan C, Kinreich S, Pandey A, Pandey G, de Viteri SS, Acion L, Bauer L, Bucholz K, Chan G, Dick D, Edenberg H, Foroud T, Goate A, Hesselbrock V, Johnson E, Kramer J, Lai D, Plawecki M, Salvatore J, Wetherill L, Agrawal A, Porjesz B, Meyers J (2024) Clinical, genomic, and neurophysiological correlates of lifetime suicide attempts among individuals with alcohol dependence. Research Square. PMID: 38405959; PMCID: PMC10889049; DOI: 10.21203/rs.3.rs-3894892/v1.
• Chorlian DB, Kamarajan C, Meyers JL, Pandey AK, Zhang J, Kinreich S, Porjesz B (2024) Non-linear development of EEG coherence in adolescents and young adults shown by the analysis of neurophysiological trajectories and their covariance. bioRxiv, 2024.2003.2013.584867. PMID: 38559025; PMCID: PMC10980032; DOI: 10.1101/2024.03.13.584867.
• Kamarajan C, Ardekani BA, Pandey AK, Meyers JL, Chorlian DB, Kinreich S, Pandey G, Richard C, de Viteri SS, Kuang W, Porjesz B (2024) Prediction of brain age in individuals with and at risk for alcohol use disorder using brain morphological features. bioRxiv, 2024.2003.2001.582844. PMID: 38496639; PMCID: PMC10942318; DOI: 10.1101/2024.03.01.582844.
• Lai D, Kuo SI, Wetherill L, Aliev F, Zhang M, Marco A, Schwantes-An TH, Dick D, Francis MW, Johnson EC, Kamarajan C, Kinreich S, Kuperman S, Meyers J, Nurnberger JI, Liu Y, Edenberg HJ, Porjesz B, Agrawal A, Foroud T, Schuckit M, Plawecki MH, Bucholz KK, McCutcheon VV (2024) Associations between alcohol use disorder polygenic score and remission in participants from high-risk families and the Indiana Biobank. Alcohol: Clinical and Experimental Research, 48(2), 283-294. PMID: 38054532; DOI: 10.1111/acer.15239.
• Li X, Liu J, Boreland AJ, Kapadia S, Zhang S, Stillitano AC, Abbo Y, Clark L, Lai D, Liu Y, Barr PB, Meyers JL, Kamarajan C, Kuang W, Agrawal A, Slesinger PA, Dick D, Salvatore J, Tischfield J, Duan J, Edenberg HJ, Kreimer A, Hart RP, Pang ZP (2024) Polygenic Risk for Alcohol Use Disorder Affects Cellular Responses to Ethanol Exposure in a Human Microglial Cell Model. bioRxiv, 2024.2002.2019.581066. DOI: 10.1101/2024.02.19.581066.
• Prytkova I, Liu Y, Fernando M, Gameiro-Ros I, Popova D, Kamarajan C, Xuei X, Chorlian DB, Edenberg HJ, Tischfield JA, Porjesz B, Pang ZP, Hart RP, Goate A, Slesinger PA (2024) Upregulated GIRK2 counteracts ethanol-induced changes in excitability & respiration in human neurons. Journal of Neuroscience. PMID: 38350999; DOI: 10.1523/JNEUROSCI.0918-23.2024.
• Thomas NS, Gillespie NA, Chan G, Edenberg HJ, Kamarajan C, Kuo SI, Miller AP, Nurnberger JI, Jr., Tischfield J, Dick DM, Salvatore JE (2024) A Developmentally-Informative Genome-wide Association Study of Alcohol Use Frequency. Behavior Genetics, 54(2), 151-168. PMID: 38108996; PMCID: PMC10913412; DOI: 10.1007/s10519-023-10170-x.
• Tobimatsu S, Kamarajan C (2024) Editorial: 15 years of frontiers in human neuroscience: neuromodulation. Frontiers in Human Neuroscience, 18; DOI: 10.3389/fnhum.2024.1380491.
• Baghdadi G, Kamarajan C, Hadaeghi F (2023) Editorial: Role of brain oscillations in neurocognitive control systems. Frontiers in Systems Neuroscience, 17, 1182496. PMID: 37064159; PMCID: PMC10102580; DOI: 10.3389/fnsys.2023.1182496.
• Barr PB, Neale Z, Schulman J, Mullins N, Zhang J, Chorlian DB, Kamarajan C, Kinreich S, Pandey AK, Pandey G, Saenz de Viteri S, Acion L, Bauer L, Bucholz KK, Chan G, Chao M, Dick DM, Edenberg HJ, Foroud T, Goate A, Hesselbrock V, Johnson EC, Kramer J, Lai D, Plawecki MH, Salvatore JE, Wetherill L, Agrawal A, Porjesz B, Meyers JL (2023) Clinical, genomic, and neurophysiological correlates of lifetime suicide attempts among individuals with alcohol dependence. medRxiv. PMID: 37162915; PMCID: PMC10168504; DOI: 10.1101/2023.04.28.23289173.
• Brislin SJ, Salvatore JE, Meyers JM, Kamarajan C, Plawecki MH, Edenberg HJ, Kuperman S, Tischfield J, Hesselbrock V, Anokhin AP, Chorlian DB, Schuckit MA, Nurnberger JI, Jr., Bauer L, Pandey G, Pandey AK, Kramer JR, Chan G, Porjesz B, Collaborators C, Dick DM (2023) Examining associations between genetic and neural risk for externalizing behaviors in adolescence and early adulthood. Psychological Medicine, 52(6), 1-11. PMID: 37203444; DOI: 10.1017/S0033291723001174.
• Chorlian DB, Meyers JL, Manz N, Zhang J, Kamarajan C, Pandey A, Wang JC, Plawecki M, Edenberg H, Goate A, Tischfield J, Porjesz B (2023) Genetic influences vary by age and sex: Trajectories of the association of cholinergic system variants and theta band event related oscillations. bioRxiv. PMID: 36909650; PMCID: PMC10002625; DOI: 10.1101/2023.02.27.530318.
• Colbert SMC, Mullins N, Chan G, Meyers JL, Schulman J, Kuperman S, Lai D, Nurnberger J, Plawecki MH, Kamarajan C, Anokhin AP, Bucholz KK, Hesselbrock V, Edenberg HJ, Kramer J, Dick DM, Porjesz B, Agrawal A, Johnson EC (2023) Polygenic Contributions to Suicidal Thoughts and Behaviors in a Sample Ascertained for Alcohol Use Disorders. Complex Psychiatry, 9(1-4), 11-23. PMID: 38058956; PMCID: PMC10697665; DOI: 10.1159/000529164.
• Gameiro-Ros I, Popova D, Prytkova I, Pang ZP, Liu Y, Dick D, Bucholz KK, Agrawal A, Porjesz B, Goate AM, Xuei X, Kamarajan C, Coga Collaborators, Tischfield JA, Edenberg HJ, Slesinger PA, Hart RP (2023) 5. Collaborative Study on the Genetics of Alcoholism: Functional genomics. Genes, Brain and Behavior, 22(5), e12855. PMID: 37533187; PMCID: PMC10550792; DOI: 10.1111/gbb.12855.
• Johnson EC, Colbert SMC, Jeffries PW, Tillman R, Bigdeli TB, Karcher NR, Chan G, Kuperman S, Meyers JL, Nurnberger JI, Plawecki MH, Degenhardt L, Martin NG, Kamarajan C, Schuckit MA, Murray RM, Dick DM, Edenberg HJ, D'Souza DC, Di Forti M, Porjesz B, Nelson EC, Agrawal A (2023) Associations Between Cannabis Use, Polygenic Liability for Schizophrenia, and Cannabis-related Experiences in a Sample of Cannabis Users. Schizophrenia Bulletin, 49(3), 778-787. PMID: 36545904; PMCID: PMC10154717; DOI: 10.1093/schbul/sbac196.
• Johnson EC, Salvatore JE, Lai D, Merikangas AK, Nurnberger JI, Tischfield JA, Xuei X, Kamarajan C, Wetherill L, Coga Collaborators, Rice JP, Kramer JR, Kuperman S, Foroud T, Slesinger PA, Goate AM, Porjesz B, Dick DM, Edenberg HJ, Agrawal A (2023) The collaborative study on the genetics of alcoholism: Genetics. Genes, Brain and Behavior, 22(5), e12856. PMID: 37387240; PMCID: PMC10550788; DOI: 10.1111/gbb.12856.
• Kamarajan C (2023) Neurophysiological, Neuroimaging, and Neuropsychological Predictors of Human Alcoholism and Risk. Behavioral Sciences, 13(10), 790. DOI: 10.3390/bs13100790.
• Kamarajan C, Pandey AK, Chorlian DB, Meyers JL, Kinreich S, Pandey G, Subbie-Saenz de Viteri S, Zhang J, Kuang W, Barr PB, Aliev F, Anokhin AP, Plawecki MH, Kuperman S, Almasy L, Merikangas A, Brislin SJ, Bauer L, Hesselbrock V, Chan G, Kramer J, Lai D, Hartz S, Bierut LJ, McCutcheon VV, Bucholz KK, Dick DM, Schuckit MA, Edenberg HJ, Porjesz B (2023) Predicting alcohol-related memory problems in older adults: A machine learning study with multi-domain features. bioRxiv, 2022.2012.2030.522330. DOI: 10.1101/2022.12.30.522330.
• Kamarajan C, Pandey AK, Chorlian DB, Meyers JL, Kinreich S, Pandey G, Subbie-Saenz de Viteri S, Zhang J, Kuang W, Barr PB, Aliev F, Anokhin AP, Plawecki MH, Kuperman S, Almasy L, Merikangas A, Brislin SJ, Bauer L, Hesselbrock V, Chan G, Kramer J, Lai D, Hartz S, Bierut LJ, McCutcheon VV, Bucholz KK, Dick DM, Schuckit MA, Edenberg HJ, Porjesz B (2023) Predicting Alcohol-Related Memory Problems in Older Adults: A Machine Learning Study with Multi-Domain Features. Behavioral Sciences (Basel), 13(5), 427. PMID: 37232664; PMCID: PMC10215235; DOI: 10.3390/bs13050427.
• Kuo SI, Thomas NS, Aliev F, Bucholz KK, Dick DM, McCutcheon VV, Meyers JL, Chan G, Kamarajan C, Kramer JR, Hesselbrock V, Plawecki MH, Porjesz B, Tischfield J, Salvatore JE (2023) Association of parental divorce, discord, and polygenic risk with children's alcohol initiation and lifetime risk for alcohol use disorder. Alcohol (Hoboken), 47(4), 724-735. PMID: 36807915; PMCID: PMC10149624; DOI: 10.1111/acer.15042.
• Meyers JL, Brislin SJ, Kamarajan C, Plawecki MH, Chorlian D, Anohkin A, Kuperman S, Merikangas A, Pandey G, Kinreich S, Pandey A, Edenberg HJ, Bucholz KK, Coga Collaborators, Almasy L, Porjesz B (2023) The collaborative study on the genetics of alcoholism: Brain function. Genes, Brain and Behavior, 22(5), e12862. PMID: 37587903; PMCID: PMC10550791; DOI: 10.1111/gbb.12862.
• Meyers JL, McCutcheon VV, Horne-Osipenko KA, Waters LR, Barr P, Chan G, Chorlian DB, Johnson EC, Kuo SI, Kramer JR, Dick DM, Kuperman S, Kamarajan C, Pandey G, Singman D, de Viteri SS, Salvatore JE, Bierut LJ, Foroud T, Goate A, Hesselbrock V, Nurnberger J, Plaweck MH, Schuckit MA, Agrawal A, Edenberg HJ, Bucholz KK, Porjesz B (2023) COVID-19 pandemic stressors are associated with reported increases in frequency of drunkenness among individuals with a history of alcohol use disorder. Translational Psychiatry, 13(1), 311. PMID: 37803048; DOI: 10.1038/s41398-023-02577-1.
• Miller AP, Kuo SI, Johnson EC, Tillman R, Brislin SJ, Dick DM, Kamarajan C, Kinreich S, Kramer J, McCutcheon VV, Plawecki MH, Porjesz B, Schuckit MA, Salvatore JE, Edenberg HJ, Bucholz KK, Meyers JL, Agrawal A, Collaborative Study on the Genetics of A (2023) Diagnostic Criteria for Identifying Individuals at High Risk of Progression From Mild or Moderate to Severe Alcohol Use Disorder. JAMA Network Open, 6(10), e2337192. PMID: 37815828; PMCID: PMC10565602; DOI: 10.1001/jamanetworkopen.2023.37192.
• Miller AP, Kuo SIC, Johnson EC, Tillman R, Brislin SJ, Dick DM, Kamarajan C, Kinreich S, Kramer J, McCutcheon VV, Plawecki MH, Porjesz B, Schuckit MA, Salvatore JE, Edenberg HJ, Bucholz KK, Meyers JL, Agrawal A (2023) Specific diagnostic criteria identify those at high risk for progression from 'preaddiction' to severe alcohol use disorder. medRxiv, 2023.2006.2012.23291164. DOI: 10.1101/2023.06.12.23291164.
• Mukundan CR, Kamarajan C, Priyanka K (2023) The World, Created By Human Minds. GAP BODHI TARU, 6(1), 22-28. LINK: https://www.gapbodhitaru.org/res/articles/(22-28)%20THE%20WORLD,%20CREATED%20BY%20HUMAN%20MINDS.pdf.
• Pandey G, Kuo SI, Horne-Osipenko KA, Pandey AK, Kamarajan C, de Viteri SS, Kinreich S, Chorlian DB, Kuang W, Stephenson M, Kramer J, Anokhin A, Zang Y, Kuperman S, Hesselbrock V, Schuckit M, Dick D, Chan G, McCutcheon VV, Edenberg H, Bucholz KK, Meyers JL, Porjesz B (2023) Associations of parent-adolescent closeness with P3 amplitude, frontal theta, and binge drinking among offspring with high risk for alcohol use disorder. Alcohol: Clinical and Experimental Research, 47(1), 155-167. PMID: 36680783; DOI: 10.1111/acer.14973.
• Popova D, Gameiro-Ros I, Youssef MM, Zalamea P, Morris AD, Prytkova I, Jadali A, Kwan KY, Kamarajan C, Salvatore JE, Xuei X, Chorlian DB, Porjesz B, Kuperman S, Dick DM, Goate A, Edenberg HJ, Tischfield JA, Pang ZP, Slesinger PA, Hart RP (2023) Alcohol reverses the effects of KCNJ6 (GIRK2) noncoding variants on excitability of human glutamatergic neurons. Molecular Psychiatry, 28(2), 746-758. PMID: 36207584; PMCID: PMC9542475; DOI: 10.1038/s41380-022-01818-x.
• Prytkova IA, Liu Y, Fernando MB, Gameiro-Ros I, Popova D, Kamarajan C, Xuei X, Chorlian DB, Edenberg HJ, Tischfield JA, Porjesz B, Pang ZP, Hart RP, Goate AM, Slesinger PA (2023) Upregulated GIRK2 counteracts ethanol-induced changes in excitability and respiration in human neurons. bioRxiv, 2023.2003.2022.533236. PMID: 36993693; PMCID: PMC10055374; DOI: 10.1101/2023.03.22.533236.
• Saenz de Viteri S, Zhang J, Johnson EC, Barr PB, Edenberg HJ, Hesselbrock VM, Nurnberger JI, Jr., Pandey AK, Kamarajan C, Kinreich S, Tischfield JA, Plawecki MH, Kramer JR, Lai D, Kuperman S, Chan G, McCutcheon VV, Bucholz KK, Porjesz B, Meyers JL (2023) Genomic risk for post-traumatic stress disorder in families densely affected with alcohol use disorders. Molecular Psychiatry, 28(8), 3391-3396. PMID: 37344610; PMCID: PMC10618091; DOI: 10.1038/s41380-023-02117-9.
• Schuckit MA, Smith TL, Danko G, Bucholz KK, Hesselbrock V, Hesselbrock M, Kuperman S, Kramer J, Nurnberger JI, Lai D, Chan G, Kamarajan C, Kuo S, Dick DM, Tear J, Mendoza LA, Edenberg HJ, Porjesz B (2023) Do personality characteristics predict future alcohol problems after considering current demography, substance use, and alcohol response? Alcohol: Clinical and Experimental Research, 47(6), 1179-1190. PMID: 37073476; DOI: 10.1111/acer.15085.
• Shah S, Shroff U, Gajiwala U, Galanter CA, Kamarajan C (2023) The Need for Psychiatric Care Among Visually Impaired Children with Traumatic Life Events: A Case Report from Rural India. Indian Journal of Mental Health, 10(2), 128-132. LINK: https://indianmentalhealth.com/pdf/2023/vol10-issue2/CR1_VISUALLY_IMPAIRED.pdf.
• Su J, Kuo SI, Aliev F, Rabinowitz JA, Jamil B, Chan G, Edenberg HJ, Francis M, Hesselbrock V, Kamarajan C, Kinreich S, Kramer J, Lai D, McCutcheon V, Meyers J, Pandey A, Pandey G, Plawecki MH, Schuckit M, Tischfield J, Dick DM (2023) Alcohol use polygenic risk score, social support, and alcohol use among European American and African American adults. Development and Psychopathology, 1-13. PMID: 37781861; DOI: 10.1017/S0954579423001141.
• Thomas NS, Salvatore JE, Kuo SI, Aliev F, McCutcheon VV, Meyers JM, Bucholz KK, Brislin SJ, Chan G, Edenberg HJ, Kamarajan C, Kramer JR, Kuperman S, Pandey G, Plawecki MH, Schuckit MA, Dick DM, Collaborators C (2023) Genetic nurture effects for alcohol use disorder. Molecular Psychiatry, 28(2), 759-766. PMID: 36253439; PMCID: PMC10079179; DOI: 10.1038/s41380-022-01816-z.
• Barr PB, Driver MN, Kuo SI, Stephenson M, Aliev F, Linner RK, Marks J, Anokhin AP, Bucholz K, Chan G, Edenberg HJ, Edwards AC, Francis MW, Hancock DB, Harden KP, Kamarajan C, Kaprio J, Kinreich S, Kramer JR, Kuperman S, Latvala A, Meyers JL, Palmer AA, Plawecki MH, Porjesz B, Rose RJ, Schuckit MA, Salvatore JE, Dick DM (2022) Clinical, environmental, and genetic risk factors for substance use disorders: characterizing combined effects across multiple cohorts. Molecular Psychiatry, 27(11), 4633-4641. PMID: 36195638; PMCID: PMC9938102; DOI: 10.1038/s41380-022-01801-6.
• Barr PB, Driver MN, Kuo SIC, Stephenson M, Aliev F, Linner RK, Anokhin AP, Bucholz K, Chan G, Edenberg HJ, Edwards AC, Francis MW, Harden KP, Kamarajan C, Kaprio J, Kinreich S, Kramer J, Kuperman S, Latvala A, Meyers JL, Palmer AA, Plawecki MH, Porjesz B, Rose RJ, Schuckit MA, Salvatore JE, Dick DM (2022) Predicting Substance Use Disorders: A Multifactorial Risk Index Combining Clinical, Environmental, and Genetic Risk Factors. medRxiv, 2022.2001.2027.22269750. DOI: 10.1101/2022.01.27.22269750.
• Barr PB, Mallard TT, Sanchez-Roige S, Poore HE, Linner RK, Porjesz B, Hesselbrock V, Foroud T, Agrawal A, Dick D, Edenberg HJ, Nurnberger J, Jr., Liu Y, Kuperman S, Kramer J, Meyers J, *Kamarajan C, Pandey A, Bierut L, Rice J, Bucholz K, Schuckit M, Tischfield J, Hart R, Salvatore J, Almasy L, Goate A, Kapoor M, Slesinger P, Scott D, Bauer L, Wetherill L, Xuei X, Lai D, O’Connor S, Plawecki M, Acion L, Chan G, Chorlian DB, Zhang J, Kinreich S, Pandey G, Chao M, Anokhin A, McCutcheon V, Saccone S, Aliev F, Chin H, Parsian A, Waldman ID, Palmer AA, Harden KP, Dick DM (2022) Parsing genetically influenced risk pathways: genetic loci impact problematic alcohol use via externalizing and specific risk. Translational Psychiatry, 12(1), 420. PMID: 36180423; PMCID: PMC9525649; DOI: 10.1038/s41398-022-02171-x.
• Brislin SJ, Salvatore JE, Meyers JL, Kamarajan C, Plawecki MH, Edenberg HJ, Kuperman S, Tischfield J, Hesselbrock V, Anokhin A, Chorlian D, Schuckit MA, Nurnberger J, Bauer L, Pandey G, Pandey AK, Kramer J, Chan G, Porjesz B, Dick D (2022) Examining associations between genetic and neural risk for externalizing behaviors in adolescence and early adulthood. PsyArXiv; DOI: 10.31234/osf.io/b64f9.
• Colbert SMC, Mullins N, Chan G, Meyers JL, Schulman J, Kuperman S, Lai D, Nurnberger J, Plawecki MH, Kamarajan C, Anokhin AP, Bucholz KK, Hesselbrock V, Edenberg HJ, Kramer J, Dick DM, Porjesz B, Agrawal A, Johnson EC (2022) Polygenic contributions to suicidal thoughts and behaviors in a sample ascertained for alcohol use disorders. medRxiv, 2022.2008.2018.22278943. DOI: 10.1101/2022.08.18.22278943.
• Francis MW, Bourdon JL, Chan G, Dick DM, Edenberg HJ, Kamarajan C, Kinreich S, Kramer J, S ICK, Pandey AK, Pandey G, Smith RL, Bucholz KK, McCutcheon VV (2022) Deriving a Measure of Social Recovery Capital From the Important People and Activities Instrument: Construction and Psychometric Properties. Alcohol and Alcoholism, 57(3), 322-329. PMID: 35356964; PMCID: PMC9086804; DOI: 10.1093/alcalc/agac014.
• Kamarajan C, Ardekani BA, Pandey AK, Kinreich S, Pandey G, Chorlian DB, Meyers JL, Zhang J, Bermudez E, Kuang W, Stimus AT, Porjesz B (2022) Differentiating Individuals with and without Alcohol Use Disorder Using Resting-State fMRI Functional Connectivity of Reward Network, Neuropsychological Performance, and Impulsivity Measures. Behavioral Sciences (Basel), 12(5), 128. PMID: 35621425; PMCID: PMC9137599; DOI: 10.3390/bs12050128.
• Kuo SI, Poore HE, Barr PB, Chirico IS, Aliev F, Bucholz KK, Chan G, Kamarajan C, Kramer JR, McCutcheon VV, Plawecki MH, Dick DM (2022) The role of parental genotype in the intergenerational transmission of externalizing behavior: Evidence for genetic nurturance. Development and Psychopathology, 1-11. PMID: 36200344; DOI: 10.1017/S0954579422000700.
• Lai D, Johnson EC, Colbert S, Pandey G, Chan G, Bauer L, Francis MW, Hesselbrock V, Kamarajan C, Kramer J, Kuang W, Kuo S, Kuperman S, Liu Y, McCutcheon V, Pang Z, Plawecki MH, Schuckit M, Tischfield J, Wetherill L, Zang Y, Edenberg HJ, Porjesz B, Agrawal A, Foroud T (2022) Evaluating risk for alcohol use disorder: Polygenic risk scores and family history. Alcoholism: Clinical and Experimental Research, 46(3), 374-383. PMID: 35267208; PMCID: PMC8928056; DOI: 10.1111/acer.14772.
• Lai D, Schwantes-An TH, Abreu M, Chan G, Hesselbrock V, Kamarajan C, Liu Y, Meyers JL, Nurnberger JI, Jr., Plawecki MH, Wetherill L, Schuckit M, Zhang P, Edenberg HJ, Porjesz B, Agrawal A, Foroud T (2022) Gene-based polygenic risk scores analysis of alcohol use disorder in African Americans. medRxiv, 2022.2001.2019.22269532. DOI: 10.1101/2022.01.19.22269532.
• Lai D, Schwantes-An TH, Abreu M, Chan G, Hesselbrock V, Kamarajan C, Liu Y, Meyers JL, Nurnberger JI, Jr., Plawecki MH, Wetherill L, Schuckit M, Zhang P, Edenberg HJ, Porjesz B, Agrawal A, Foroud T (2022) Gene-based polygenic risk scores analysis of alcohol use disorder in African Americans. Translational Psychiatry, 12(1), 266. PMID: 35790736; DOI: 10.1038/s41398-022-02029-2.
• Merikangas AK, Kember RL, Plawecki MH, Kamarajan C, Chan G, Bauer L, Meyers JL, Nurnberger JI, Kramer J, Porjesz B, Edenberg HJ, Almasy L (2022) Is anxiety a pathway to Alcohol Use Disorders? A phenome-wide association study of the GABRA2 coding variant rs279858. medRxiv, 2022.2011.2021.22282301. DOI: 10.1101/2022.11.21.22282301.
• Mukundan CR, Kamarajan C (2022) Brain to Mind - Cognitive and Emotional Journey within the Human Brain. EC Neurology, 14(2), 01-08. LINK: https://www.ecronicon.com/ecne/pdf/ECNE-14-00994.pdf.
• Mukundan CR, Kamarajan C, Kacker P (2022) Brain to Mind – Moving from Physical to Conceptual World. GAP Indian Journal of Forensics and Behavioral Sciences, 3(1), 18-25. LINK: https://www.gapijfbs.org/res/articles/(18-25)%20BRAIN%20TO%20MIND%20MOVING%20FROM%20PHYSICAL%20TO%20CONCEPTUAL%20WORLD.pdf.
• Nurnberger JI, Jr., Wang Y, Zang Y, Lai D, Wetherill L, Edenberg HJ, Aliev F, Plawecki MH, Chorlian D, Chan G, Bucholz K, Bauer L, Kamarajan C, Salvatore JE, Kapoor M, Hesselbrock V, Dick D, Bierut L, McCutcheon V, Meyers JL, Porjesz B, Kramer J, Kuperman S, Kinreich S, Anokhin AP, Collaborative Study on the Genetics of A (2022) High Polygenic Risk Scores Are Associated With Early Age of Onset of Alcohol Use Disorder in Adolescents and Young Adults at Risk. Biological Psychiatry: Global Open Science, 2(4), 379-388. PMID: 36324664; PMCID: PMC9616304; DOI: 10.1016/j.bpsgos.2021.10.007.
• Pandey AK, Ardekani BA, Byrne KN, Kamarajan C, Zhang J, Pandey G, Meyers JL, Kinreich S, Chorlian DB, Kuang W, Stimus AT, Porjesz B (2022) Statistical Nonparametric fMRI Maps in the Analysis of Response Inhibition in Abstinent Individuals with History of Alcohol Use Disorder. Behavioral Sciences (Basel), 12(5), 121. PMID: 35621418; PMCID: PMC9137506; DOI: 10.3390/bs12050121.
• Plawecki MH, Boes J, Wetherill L, Kosobud AEK, Stangl BL, Ramchandani VA, Zimmermann US, Nurnberger JI, Jr., Schuckit M, Edenberg HJ, Pandey G, Kamarajan C, Porjesz B, Foroud T, O'Connor S (2022) Binge and high-intensity drinking-Associations with intravenous alcohol self-administration and underlying risk factors. Addiction Biology, 27(6), e13228. PMID: 36301209; PMCID: PMC9786574; DOI: 10.1111/adb.13228.
• Popova D, Gameiro-Ros I, Youssef MM, Zalamea P, Morris AD, Prytkova I, Jadali A, Kwan KY, Kamarajan C, Salvatore JE, Xuei X, Chorlian DB, Porjesz B, Kuperman S, Dick DM, Goate A, Edenberg HJ, Tischfield JA, Pang ZP, Slesinger PA, Hart RP (2022) Alcohol reverses the effects of KCNJ6 (GIRK2) noncoding variants on excitability of human glutamatergic neurons. bioRxiv, 2022.2005.2024.493086. DOI: 10.1101/2022.05.24.493086.
• Stephenson M, Aliev F, Kuo SIC, Edwards AC, Pandey G, Su J, Kamarajan C, Dick D, Salvatore JE (2022) The role of adolescent social relationships in promoting alcohol resistance: Interrupting the intergenerational transmission of alcohol misuse. Development and Psychopathology, 1-15. DOI: 10.1017/S0954579422000785.
• Thomas NS, Barr P, Aliev F, Stephenson M, Kuo SI, Chan G, Dick DM, Edenberg HJ, Hesselbrock V, Kamarajan C, Kuperman S, Salvatore JE (2022) Principal Component Analysis Reduces Collider Bias in Polygenic Score Effect Size Estimation. Behavior Genetics, 52(4-5), 268-280. PMID: 35674916; PMCID: PMC10103419; DOI: 10.1007/s10519-022-10104-z.
• Thomas NS, Kuo SI, Aliev F, McCutcheon VV, Meyers JM, Chan G, Hesselbrock V, Kamarajan C, Kinreich S, Kramer JR, Kuperman S, Lai D, Plawecki MH, Porjesz B, Schuckit MA, Dick DM, Bucholz KK, Salvatore JE (2022) Alcohol use disorder, psychiatric comorbidities, marriage and divorce in a high-risk sample. Psychology of Addictive Behaviors, 36(4), 364-374. PMID: 35617219; PMCID: PMC9247836; DOI: 10.1037/adb0000840.
• Tielbeek JJ, Uffelmann E, Williams BS, Colodro-Conde L, Gagnon E, Mallard TT, Levitt BE, Jansen PR, Johansson A, Sallis HM, Pistis G, Saunders GRB, Allegrini AG, Rimfeld K, Konte B, Klein M, Hartmann AM, Salvatore JE, Nolte IM, Demontis D, Malmberg ALK, Burt SA, Savage JE, Sugden K, Poulton R, Harris KM, Vrieze S, McGue M, Iacono WG, Mota NR, Mill J, Viana JF, Mitchell BL, Morosoli JJ, Andlauer TFM, Ouellet-Morin I, Tremblay RE, Cote SM, Gouin JP, Brendgen MR, Dionne G, Vitaro F, Lupton MK, Martin NG, COGA Consortium*, Spit for Science Working G, Castelao E, Raikkonen K, Eriksson JG, Lahti J, Hartman CA, Oldehinkel AJ, Snieder H, Liu H, Preisig M, Whipp A, Vuoksimaa E, Lu Y, Jern P, Rujescu D, Giegling I, Palviainen T, Kaprio J, Harden KP, Munafo MR, Morneau-Vaillancourt G, Plomin R, Viding E, Boutwell BB, Aliev F, Dick DM, Popma A, Faraone SV, Borglum AD, Medland SE, Franke B, Boivin M, Pingault JB, Glennon JC, Barnes JC, Fisher SE, Moffitt TE, Caspi A, Polderman TJC, Posthuma D (2022) Uncovering the genetic architecture of broad antisocial behavior through a genome-wide association study meta-analysis. Molecular Psychiatry, 27(11), 4453-4463. PMID: 36284158; DOI: 10.1038/s41380-022-01793-3.
• Bender AK, Meyers JL, di Viteri SS, Schuckit M, Chan G, Acion L, Kamarajan C, Kramer J, Anohkin A, Kinreich S, Pandey A, Hesselbrock V, Hesselbrock M, Bucholz KK, McCutcheon VV (2021) A latent class analysis of alcohol and posttraumatic stress symptoms among offspring of parents with and without alcohol use disorder. Addictive Behaviors, 112, 106640. PMID: 32957005; DOI: 10.1016/j.addbeh.2020.106640.
• Johnson EC, Aliev F, Meyers JL, Salvatore JE, Tillman R, Chang Y, Docherty AR, Bogdan R, Acion L, Chan G, Chorlian DB, Kamarajan C, Kuperman S, Pandey A, Plawecki MH, Schuckit M, Tischfield J, Edenberg HJ, Bucholz KK, Nurnberger JI, Porjesz B, Hesselbrock V, Dick DM, Kramer JR, Agrawal A (2021) Associations between Suicidal Thoughts and Behaviors and Genetic Liability for Cognitive Performance, Depression, and Risk-Taking in a High-Risk Sample. Complex Psychiatry, 7(1-2), 34-44. PMID: 35592092; PMCID: PMC8443930; DOI: 10.1159/000517169.
• Kapoor M, Chao MJ, Johnson EC, Novikova G, Lai D, Meyers JL, Schulman J, Nurnberger JI, Jr., Porjesz B, Liu Y, Hesselbrock V, Kuperman S, Kramer J, *Kamarajan C, Pandey A, Bierut L, Rice JP, Bucholz KK, Schuckit M, Tischfield J, Brooks A, Hart RP, Almasy L, Dick D, Salvatore J, Slesinger P, Foroud T, Edenberg HJ, Marcora E, Agrawal A, Goate A (2021) Multi-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases. Nature Communications, 12(1), 5071. PMID: 34417470; PMCID: PMC8379159; DOI: 10.1038/s41467-021-25392-y.
• Karlsson Linner R, Mallard TT, Barr PB, Sanchez-Roige S, Madole JW, Driver MN, Poore HE, de Vlaming R, Grotzinger AD, Tielbeek JJ, Johnson EC, Liu M, Rosenthal SB, Ideker T, Zhou H, Kember RL, Pasman JA, Verweij KJH, Liu DJ, Vrieze S, Porjesz B, Hesselbrock V, Foroud TM, Agrawal A, Edenberg HJ, Nurnberger Jr JI, Liu Y, Kuperman S, Kramer J, Meyer JL, *Kamarajan C, Pandey AK, Bierut L, Rice J, Bucholz KK, Schuckit MA, Tischfield J, Brooks A, Hart RP, Almasy L, Dick DM, Salvatore JE, Goate A, Kapoor M, Slesinger P, Scott DM, Bauer L, Wetherill L, Xuei X, Lai D, O'Connor SJ, Plawecki MH, Lourens S, Acion L, Chan G, Chorlian DB, Zhang J, Kinreich S, Pandey G, Chao MJ, Anokhin AP, McCutcheon VV, Saccone S, Aliev F, Barr PB, Chin H, Parsian A, Kranzler HR, Gelernter J, Harris KM, Tucker-Drob EM, Waldman ID, Palmer AA, Harden KP, Koellinger PD, Dick DM (2021) Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction. Nature Neuroscience, 24(10), 1367-1376. PMID: 34446935; PMCID: PMC8484054; DOI: 10.1038/s41593-021-00908-3.
• Kinreich S, McCutcheon VV, Aliev F, Meyers JL, Kamarajan C, Pandey AK, Chorlian DB, Zhang J, Kuang W, Pandey G, Viteri SS, Francis MW, Chan G, Bourdon JL, Dick DM, Anokhin AP, Bauer L, Hesselbrock V, Schuckit MA, Nurnberger JI, Jr., Foroud TM, Salvatore JE, Bucholz KK, Porjesz B (2021) Predicting alcohol use disorder remission: a longitudinal multimodal multi-featured machine learning approach. Translational Psychiatry, 11(1), 166. PMID: 33723218; PMCID: PMC7960734; DOI: 10.1038/s41398-021-01281-2.
• Kinreich S, Meyers JL, Maron-Katz A, Kamarajan C, Pandey AK, Chorlian DB, Zhang J, Pandey G, Subbie-Saenz de Viteri S, Pitti D, Anokhin AP, Bauer L, Hesselbrock V, Schuckit MA, Edenberg HJ, Porjesz B (2021) Predicting risk for Alcohol Use Disorder using longitudinal data with multimodal biomarkers and family history: a machine learning study. Molecular Psychiatry, 26(4), 1133-1141. PMID: 31595034; PMCID: PMC7138692; DOI: 10.1038/s41380-019-0534-x.
• Kuo SI, Salvatore JE, Barr PB, Aliev F, Anokhin A, Bucholz KK, Chan G, Edenberg HJ, Hesselbrock V, Kamarajan C, Kramer JR, Lai D, Mallard TT, Nurnberger JI, Jr., Pandey G, Plawecki MH, Sanchez-Roige S, Waldman I, Palmer AA, Externalizing Consortium, Dick DM (2021) Mapping Pathways by Which Genetic Risk Influences Adolescent Externalizing Behavior: The Interplay Between Externalizing Polygenic Risk Scores, Parental Knowledge, and Peer Substance Use. Behavior Genetics, 51(5), 543-558. PMID: 34117972; PMCID: PMC8403154; DOI: 10.1007/s10519-021-10067-7.
• Lai D, Kapoor M, Wetherill L, Schwandt M, Ramchandani VA, Goldman D, Chao M, Almasy L, Bucholz K, Hart RP, Kamarajan C, Meyers JL, Nurnberger JI, Tischfield J, Edenberg HJ, Schuckit M, Goate A, Scott DM, Porjesz B, Agrawal A, Foroud T (2021) Genome-wide admixture mapping of DSM-IV alcohol dependence, criterion count, and the self-rating of the effects of ethanol in African American populations. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 186(3), 151-161. PMID: 32652861; PMCID: PMC9376735; DOI: 10.1002/ajmg.b.32805.
• Meyers JL, Chorlian DB, Bigdeli TB, Johnson EC, Aliev F, Agrawal A, Almasy L, Anokhin A, Edenberg HJ, Foroud T, Goate A, Kamarajan C, Kinreich S, Nurnberger J, Pandey AK, Pandey G, Plawecki MH, Salvatore JE, Zhang J, Fanous A, Porjesz B (2021) The association of polygenic risk for schizophrenia, bipolar disorder, and depression with neural connectivity in adolescents and young adults: examining developmental and sex differences. Translational Psychiatry, 11(1), 54. PMID: 33446638; PMCID: PMC7809462; DOI: 10.1038/s41398-020-01185-7.
• Meyers JL, Zhang J, Chorlian DB, Pandey AK, Kamarajan C, Wang JC, Wetherill L, Lai D, Chao M, Chan G, Kinreich S, Kapoor M, Bertelsen S, McClintick J, Bauer L, Hesselbrock V, Kuperman S, Kramer J, Salvatore JE, Dick DM, Agrawal A, Foroud T, Edenberg HJ, Goate A, Porjesz B (2021) A genome-wide association study of interhemispheric theta EEG coherence: implications for neural connectivity and alcohol use behavior. Molecular Psychiatry, 26(9), 5040-5052. PMID: 32433515; PMCID: PMC8503860; DOI: 10.1038/s41380-020-0777-6.
• Mukundan CR, Kamarajan C (2021) Brain to Mind: Creation of the Virtual World. Advances in Social Sciences Research Journal, 8(10), 513-544. DOI: 10.14738/assrj.810.11102.
• Su J, Kuo SI, Aliev F, Chan G, Edenberg HJ, Kamarajan C, McCutcheon VV, Meyers JL, Schuckit M, Tischfield J, Dick DM (2021) The associations between polygenic risk, sensation seeking, social support, and alcohol use in adulthood. Journal of Abnormal Psychology, 130(5), 525-536. PMID: 34472888; DOI: 10.1037/abn0000568.
• Tielbeek JJ, Emil U, Benjamin SW, Lucía C-C, Éloi G, Travis TM, Brandt L, Philip RJ, Ada J, Hannah S, Giorgio P, Gretchen RBS, Andrea GA, Kaili R, Bettina K, Marieke K, Annette MH, Jessica ES, Ilja MN, Ditte D, Anni M, Burt SA, Jeanne S, Karen S, Richie P, Kathleen Mullan H, Scott V, Matt M, William GI, Nina Roth M, Jonathan M, Joana FV, Brittany LM, Jose JM, Till A, Isabelle O-M, Richard ET, Sylvana C, Jean-Philippe G, Mara B, Ginette D, Frank V, Michelle KL, Nicholas GM, COGA Consortium, Spit for Science Working Group, Enrique C, Katri R, Johan E, Jari L, Catharina AH, Albertine JO, Harold S, Hexuan L, Martin P, Alyce W, Eero V, Yi L, Patrick J, Dan R, Ina G, Teemu P, Jaakko K, Kathryn Paige H, Marcus RM, Geneviève M-V, Robert P, Essi V, Brian B, Fazil A, Danielle D, Arne P, Stephen VF, Anders B, Sarah EM, Barbara F, Michel B, Jean-Baptiste P, Jeffrey CG, James CB, Simon EF, Terrie EM, Avshalom C, Tinca JCP, Danielle P, Broad Antisocial Behavior Consortium collaborators (2021) Uncovering the Genetic Architecture of Broad Antisocial Behavior through a Genome-Wide Association Study Meta-analysis. bioRxiv, 2021.2010.2019.462578. DOI: 10.1101/2021.10.19.462578v1.
• Barr PB, Ksinan A, Su J, Johnson EC, Meyers JL, Wetherill L, Latvala A, Aliev F, Chan G, Kuperman S, Nurnberger J, Kamarajan C, Anokhin A, Agrawal A, Rose RJ, Edenberg HJ, Schuckit M, Kaprio J, Dick DM (2020) Using polygenic scores for identifying individuals at increased risk of substance use disorders in clinical and population samples. Translational Psychiatry, 10(1), 196. PMID: 32555147; PMCID: PMC7303212; DOI: 10.1038/s41398-020-00865-8.
• Bourdon JL, Tillman R, Francis MW, Dick DM, Stephenson M, Kamarajan C, Edenberg HJ, Kramer J, Kuperman S, Bucholz KK, McCutcheon VV (2020) Characterization of Service Use for Alcohol Problems Across Generations and Sex in Adults With Alcohol Use Disorder. Alcoholism: Clinical and Experimental Research, 44(3), 746-757. PMID: 31984526; PMCID: PMC7069784; DOI: 10.1111/acer.14290.
• Chester DS, Bucholz KK, Chan G, Kamarajan C, Pandey AK, Wetherill L, Kramer JR, Nurnberger JI, Jr., Salvatore JE, Dick DM (2020) Alcohol-Related, Drug-Related, and Non-Substance-Related Aggression: 3 Facets of a Single Construct or 3 Distinct Constructs? Alcoholism: Clinical and Experimental Research, 44(9), 1852-1861. PMID: 32761940; PMCID: PMC7722121; DOI: 10.1111/acer.14412.
• Kamarajan C, Ardekani BA, Pandey AK, Chorlian DB, Kinreich S, Pandey G, Meyers JL, Zhang J, Kuang W, Stimus AT, Porjesz B (2020) Random Forest Classification of Alcohol Use Disorder Using EEG Source Functional Connectivity, Neuropsychological Functioning, and Impulsivity Measures. Behavioral Sciences (Basel), 10(3), 62. PMID: 32121585; PMCID: PMC7139327; DOI: 10.3390/bs10030062.
• Kamarajan C, Ardekani BA, Pandey AK, Kinreich S, Pandey G, Chorlian DB, Meyers JL, Zhang J, Bermudez E, Stimus AT, Porjesz B (2020) Random Forest Classification of Alcohol Use Disorder Using fMRI Functional Connectivity, Neuropsychological Functioning, and Impulsivity Measures. Brain Sciences, 10(2), 115. PMID: 32093319; PMCID: PMC7071377; DOI: 10.3390/brainsci10020115.
• Mukundan CR, Kamarajan C (2020) The real physical world and the virtual mental world. Journal of Psychology and Clinical Psychiatry, 11(6), 170-175. DOI: 10.15406/jpcpy.2020.11.0069.
• Pandey G, Seay MJ, Meyers JL, Chorlian DB, Pandey AK, Kamarajan C, Ehrenberg M, Pitti D, Kinreich S, Subbie-Saenz de Viteri S, Acion L, Anokhin A, Bauer L, Chan G, Edenberg H, Hesselbrock V, Kuperman S, McCutcheon VV, Bucholz KK, Schuckit M, Porjesz B (2020) Density and Dichotomous Family History Measures of Alcohol Use Disorder as Predictors of Behavioral and Neural Phenotypes: A Comparative Study Across Gender and Race/Ethnicity. Alcoholism: Clinical and Experimental Research, 44(3), 697-710. PMID: 31957047; PMCID: PMC8357185; DOI: 10.1111/acer.14280.
• Subbie-Saenz de Viteri S, Pandey A, Pandey G, Kamarajan C, Smith R, Anokhin A, Bauer L, Bender A, Chan G, Dick D, Edenberg H, Kinreich S, Kramer J, Schuckit M, Zang Y, McCutcheon V, Bucholz K, Porjesz B, Meyers JL (2020) Pathways to post-traumatic stress disorder and alcohol dependence: Trauma, executive functioning, and family history of alcoholism in adolescents and young adults. Brain and Behavior, 10(11), e01789. PMID: 32990406; PMCID: PMC7667345; DOI: 10.1002/brb3.1789.
• Barr PB, Ksinan A, Su J, Johnson EC, Meyers JL, Wetherill L, Latvala A, Aliev F, Chan G, Kuperman S, Nurnberger J, Kamarajan C, Anokhin A, Agrawal A, Rose RJ, Edenberg HJ, Schuckit M, Kaprio J, Dick DM (2019) Polygenic Prediction of Substance Use Disorders in Clinical and Population Samples. bioRxiv, 748038. DOI: 10.1101/748038.
• Kamarajan C (2019) Brain Electrophysiological Signatures in Human Alcoholism and Risk. In: Preedy VR (ed.), The Neuroscience of Alcohol: Mechanisms and Treatment, Elsevier Academic Press, San Diego, USA, pp. 119-130. DOI: 10.1016/B978-0-12-813125-1.00013-1.
• Kamarajan C (2019) Neural Reward Processing in Human Alcoholism and Risk: A Focus on Event‐Related Potentials, Oscillations, and Neuroimaging. In: Preedy VR (ed.), The Neuroscience of Alcohol: Mechanisms and Treatment, Elsevier Academic Press, San Diego, USA, pp. 259-267. DOI: 10.1016/B978-0-12-813125-1.00027-1.
• Lai D, Wetherill L, Bertelsen S, Carey CE, Kamarajan C, Kapoor M, Meyers JL, Anokhin AP, Bennett DA, Bucholz KK, Chang KK, De Jager PL, Dick DM, Hesselbrock V, Kramer J, Kuperman S, Nurnberger JI, Jr., Raj T, Schuckit M, Scott DM, Taylor RE, Tischfield J, Hariri AR, Edenberg HJ, Agrawal A, Bogdan R, Porjesz B, Goate AM, Foroud T (2019) Genome-wide association studies of alcohol dependence, DSM-IV criterion count and individual criteria. Genes, Brain and Behavior, 18(6), e12579. PMID: 31090166; PMCID: PMC6612573; DOI: 10.1111/gbb.12579.
• Meyers J, McCutcheon VV, Pandey AK, Kamarajan C, Subbie S, Chorlian D, Salvatore J, Pandey G, Almasy L, Anokhin A, Bauer L, Bender A, Dick DM, Edenberg HJ, Hesselbrock V, Kramer J, Kuperman S, Agrawal A, Bucholz K, Porjesz B (2019) Early Sexual Trauma Exposure and Neural Response Inhibition in Adolescence and Young Adults: Trajectories of Frontal Theta Oscillations During a Go/No-Go Task. Journal of the American Academy of Child and Adolescent Psychiatry, 58(2), 242-255 e242. PMID: 30738551; PMCID: PMC6537865; DOI: 10.1016/j.jaac.2018.07.905.
• Meyers JL, Chorlian DB, Johnson EC, Pandey AK, Kamarajan C, Salvatore JE, Aliev F, Subbie-Saenz de Viteri S, Zhang J, Chao M, Kapoor M, Hesselbrock V, Kramer J, Kuperman S, Nurnberger J, Tischfield J, Goate A, Foroud T, Dick DM, Edenberg HJ, Agrawal A, Porjesz B (2019) Association of Polygenic Liability for Alcohol Dependence and EEG Connectivity in Adolescence and Young Adulthood. Brain Sciences, 9(10), 280. PMID: 31627376; PMCID: PMC6826735; DOI: 10.3390/brainsci9100280.
• Mukundan CR, Kamarajan C, Ajayan P (2019) Live and die - develop a mind within, while living, using which one learns to create ideas, functional systems, and knowledge; and die later, when the mind ceases to be present. Journal of Psychology and Clinical Psychiatry, 10(6), 234‒239. DOI: 10.15406/jpcpy.2019.10.00659.
• Mukundan CR, Kamarajan C, Ajayan P (2019) Mind in the brain - creation of the greatest virtual world. Journal of Psychology and Clinical Psychiatry, 10(2), 83-90. DOI: 10.15406/jpcpy.2019.10.00633.
• Wetherill L, Lai D, Johnson EC, Anokhin A, Bauer L, Bucholz KK, Dick DM, Hariri AR, Hesselbrock V, Kamarajan C, Kramer J, Kuperman S, Meyers JL, Nurnberger JI, Jr., Schuckit M, Scott DM, Taylor RE, Tischfield J, Porjesz B, Goate AM, Edenberg HJ, Foroud T, Bogdan R, Agrawal A (2019) ERRATUM: Genome-wide association study identifies loci associated with liability to alcohol and drug dependence that is associated with variability in reward-related ventral striatum activity in African- and European-Americans. Genes, Brain and Behavior, 18(8), e12608. PMID: 31667958; DOI: 10.1111/gbb.12608.
• Wetherill L, Lai D, Johnson EC, Anokhin A, Bauer L, Bucholz KK, Dick DM, Hariri AR, Hesselbrock V, Kamarajan C, Kramer J, Kuperman S, Meyers JL, Nurnberger JI, Jr., Schuckit M, Scott DM, Taylor RE, Tischfield J, Porjesz B, Goate AM, Edenberg HJ, Foroud T, Bogdan R, Agrawal A (2019) Genome-wide association study identifies loci associated with liability to alcohol and drug dependence that is associated with variability in reward-related ventral striatum activity in African- and European-Americans. Genes, Brain and Behavior, 18(6), e12580. PMID: 31099175; PMCID: PMC6726116; DOI: 10.1111/gbb.12580.
• Pandey AK, Ardekani BA, Kamarajan C, Zhang J, Chorlian DB, Byrne KN, Pandey G, Meyers JL, Kinreich S, Stimus A, Porjesz B (2018) Lower Prefrontal and Hippocampal Volume and Diffusion Tensor Imaging Differences Reflect Structural and Functional Abnormalities in Abstinent Individuals with Alcohol Use Disorder. Alcoholism: Clinical and Experimental Research, 42(10), 1883-1896. PMID: 30118142; PMCID: PMC6167190; DOI: 10.1111/acer.13854.
• Chorlian DB, Rangaswamy M, Manz N, Meyers JL, Kang SJ, Kamarajan C, Pandey AK, Wang JC, Wetherill L, Edenberg H, Porjesz B (2017) Genetic correlates of the development of theta event related oscillations in adolescents and young adults. International Journal of Psychophysiology, 115, 24-39. PMID: 27847216; PMCID: PMC5456461; DOI: 10.1016/j.ijpsycho.2016.11.007.
• Kamarajan C, Pandey AK, Chorlian DB, Manz N, Stimus AT, Edenberg HJ, Wetherill L, Schuckit M, Wang JC, Kuperman S, Kramer J, Tischfield JA, Porjesz B (2017) A KCNJ6 gene polymorphism modulates theta oscillations during reward processing. International Journal of Psychophysiology, 115, 13-23. PMID: 27993610; PMCID: PMC5392377; DOI: 10.1016/j.ijpsycho.2016.12.007.
• Mathies LD, Aliev F, Porjesz B, Hesselbrock V, Edenberg H, Bierut L, Nurnberger Jr J, Foroud T, Kuperman S, Kramer J, Bierut L, Rice J, Bucholz K, Agrawal A, Schuckit M, Tischfield J, Brooks A, Almasy L, Goate A, Taylor R, Bauer L, McClintick J, Wetherill L, Xuei X, Liu Y, Lai D, O'Connor S, Plawecki M, Lourens S, Chan G, Meyers J, Chorlian D, *Kamarajan C, Pandey A, Zhang J, Wang J-C, Kapoor M, Bertelsen S, Anokhin A, McCutcheon V, Saccone S, Salvatore J, Cho B, Kos M, Parsian A, Reilly M, Davies AG, Dick DM, Bettinger JC (2017) Variation in SWI/SNF Chromatin Remodeling Complex Proteins is Associated with Alcohol Dependence and Antisocial Behavior in Human Populations. Alcoholism: Clinical and Experimental Research, 41(12), 2033-2040. PMID: 28981154; PMCID: PMC5711565; DOI: 10.1111/acer.13514.
• Meyers JL, Zhang J, Manz N, Rangaswamy M, Kamarajan C, Wetherill L, Chorlian DB, Kang SJ, Bauer L, Hesselbrock V, Kramer J, Kuperman S, Nurnberger JI, Jr., Tischfield J, Wang JC, Edenberg HJ, Goate A, Foroud T, Porjesz B (2017) A genome wide association study of fast beta EEG in families of European ancestry. International Journal of Psychophysiology, 115, 74-85. PMID: 28040410; PMCID: PMC5426060; DOI: 10.1016/j.ijpsycho.2016.12.008.
• Meyers JL, Zhang J, Wang JC, Su J, Kuo SI, Kapoor M, Wetherill L, Bertelsen S, Lai D, Salvatore JE, Kamarajan C, Chorlian D, Agrawal A, Almasy L, Bauer L, Bucholz KK, Chan G, Hesselbrock V, Koganti L, Kramer J, Kuperman S, Manz N, Pandey A, Seay M, Scott D, Taylor RE, Dick DM, Edenberg HJ, Goate A, Foroud T, Porjesz B (2017) An endophenotype approach to the genetics of alcohol dependence: a genome wide association study of fast beta EEG in families of African ancestry. Molecular Psychiatry, 22(12), 1767-1775. PMID: 28070124; PMCID: PMC5503794; DOI: 10.1038/mp.2016.239.
• Pandey AK, Kamarajan C, Manz N, Chorlian DB, Stimus A, Porjesz B (2016) Delta, theta, and alpha event-related oscillations in alcoholics during Go/NoGo task: Neurocognitive deficits in execution, inhibition, and attention processing. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 65, 158-171. PMID: 26456730; PMCID: PMC4679474; DOI: 10.1016/j.pnpbp.2015.10.002.
• Chorlian DB, Rangaswamy M, Manz N, Kamarajan C, Pandey AK, Edenberg H, Kuperman S, Porjesz B (2015) Gender modulates the development of theta event related oscillations in adolescents and young adults. Behavioural Brain Research, 292(1), 342-352. PMID: 26102560; PMCID: PMC4705839; DOI: 10.1016/j.bbr.2015.06.020.
• Kamarajan C, Pandey AK, Chorlian DB, Manz N, Stimus AT, Anokhin AP, Bauer LO, Kuperman S, Kramer J, Bucholz KK, Schuckit MA, Hesselbrock VM, Porjesz B (2015) Deficient Event-Related Theta Oscillations in Individuals at Risk for Alcoholism: A Study of Reward Processing and Impulsivity Features. PLOS ONE, 10(11), e0142659. PMID: 26580209; PMCID: PMC4651365; DOI: 10.1371/journal.pone.0142659.
• Kamarajan C, Pandey AK, Chorlian DB, Manz N, Stimus AT, Bauer LO, Hesselbrock VM, Schuckit MA, Kuperman S, Kramer J, Porjesz B (2015) Reward processing deficits and impulsivity in high-risk offspring of alcoholics: A study of event-related potentials during a monetary gambling task. International Journal of Psychophysiology, 98(2 Pt 1), 182-200. PMID: 26388585; PMCID: PMC4898464; DOI: 10.1016/j.ijpsycho.2015.09.005.
• Kamarajan C, Pandey AK, Chorlian DB, Porjesz B (2015) The use of current source density as electrophysiological correlates in neuropsychiatric disorders: A review of human studies. International Journal of Psychophysiology, 97(3), 310-322. PMID: 25448264; PMCID: PMC4422780; DOI: 10.1016/j.ijpsycho.2014.10.013.
• Kamarajan C, Porjesz B (2015) Advances in Electrophysiological Research. Alcohol Research: Current Reviews, 37(1), 53-87. PMID: 26259089; PMCID: PMC4476604. LINK: https://www.ncbi.nlm.nih.gov/pubmed/26259089.
• Mukundan CR, Kamarajan C, Ajayan P, Roopesh BN, Sharma M (2013) The frontal cortex and recognition: Neurocognitive findings of hypnosis. Indian Journal of Health and Wellbeing, 4(4), 703-710. LINK: http://www.i-scholar.in/index.php/ijhw/article/view/92255.
• Kamarajan C, Porjesz B (2012) Brain waves in Impulsivity Spectrum Disorders. In: Cyders MA (ed.), Psychology of Impulsivity, Nova Science Publishers, Hauppauge, NY, pp. 20-93. LINK: https://novapublishers.com/shop/psychology-of-impulsivity/.
• Kamarajan C, Rangaswamy M, Manz N, Chorlian DB, Pandey AK, Roopesh BN, Porjesz B (2012) Topography, power, and current source density of theta oscillations during reward processing as markers for alcohol dependence. Human Brain Mapping, 33(5), 1019-1039. PMID: 21520344; PMCID: PMC3763910; DOI: 10.1002/hbm.21267.
• Pandey AK, Kamarajan C, Rangaswamy M, Porjesz B (2012) Event-Related Oscillations in Alcoholism Research: A Review. Journal of Addiction Research & Therapy, Suppl 7(1), 1-13. PMID: 24273686; PMCID: PMC3835599; DOI: 10.4172/2155-6105.S7-001.
• Pandey AK, Kamarajan C, Tang Y, Chorlian DB, Roopesh BN, Manz N, Stimus A, Rangaswamy M, Porjesz B (2012) Neurocognitive deficits in male alcoholics: an ERP/sLORETA analysis of the N2 component in an equal probability Go/NoGo task. Biological Psychology, 89(1), 170-182. PMID: 22024409; PMCID: PMC3245806; DOI: 10.1016/j.biopsycho.2011.10.009.
• Rao NR, Kodali R, Mian A, Ramtekkar U, Kamarajan C, Jibson MD (2012) Psychiatric residents' attitudes toward and experiences with the clinical-skills verification process: a pilot study on U.S. and international medical graduates. Academic Psychiatry, 36(4), 316-322. PMID: 22851030; DOI: 10.1176/appi.ap.11030051.
• Garrett M, Singh A, Amanbekova D, Kamarajan C (2011) Lack of insight and conceptions of “mental illness” in schizophrenia, assessed in the third person through case vignettes. Psychosis, 3(2), 115-125. DOI: 10.1080/17522439.2010.529618.
• Kamarajan C, Rangaswamy M, Tang Y, Chorlian DB, Pandey AK, Roopesh BN, Manz N, Saunders R, Stimus AT, Porjesz B (2010) Dysfunctional reward processing in male alcoholics: an ERP study during a gambling task. Journal of Psychiatric Research, 44(9), 576-590. PMID: 20035952; PMCID: PMC2878886; DOI: 10.1016/j.jpsychires.2009.11.019.
• Roopesh BN, Rangaswamy M, Kamarajan C, Chorlian DB, Pandey AK, Porjesz B (2010) Reduced resource optimization in male alcoholics: N400 in a lexical decision paradigm. Alcoholism: Clinical and Experimental Research, 34(11), 1905-1914. PMID: 20659074; PMCID: PMC3601919; DOI: 10.1111/j.1530-0277.2010.01279.x.
• Kamarajan C, Porjesz B, Rangaswamy M, Tang Y, Chorlian DB, Padmanabhapillai A, Saunders R, Pandey AK, Roopesh BN, Manz N, Stimus AT, Begleiter H (2009) Brain signatures of monetary loss and gain: outcome-related potentials in a single outcome gambling task. Behavioural Brain Research, 197(1), 62-76. PMID: 18775749; PMCID: PMC2645043; DOI: 10.1016/j.bbr.2008.08.011.
• Roopesh BN, Rangaswamy M, Kamarajan C, Chorlian DB, Stimus A, Bauer LO, Rohrbaugh J, O'Connor SJ, Kuperman S, Schuckit M, Porjesz B (2009) Priming deficiency in male subjects at risk for alcoholism: the N4 during a lexical decision task. Alcoholism: Clinical and Experimental Research, 33(12), 2027-2036. PMID: 19764939; PMCID: PMC3601897; DOI: 10.1111/j.1530-0277.2009.01042.x.
• Kamarajan C, Rangaswamy M, Chorlian DB, Manz N, Tang Y, Pandey AK, Roopesh BN, Stimus AT, Porjesz B (2008) Theta oscillations during the processing of monetary loss and gain: a perspective on gender and impulsivity. Brain Research, 1235, 45-62. PMID: 18616934; PMCID: PMC2650440; DOI: 10.1016/j.brainres.2008.06.051.
• Chen AC, Porjesz B, Rangaswamy M, Kamarajan C, Tang Y, Jones KA, Chorlian DB, Stimus AT, Begleiter H (2007) Reduced frontal lobe activity in subjects with high impulsivity and alcoholism. Alcoholism: Clinical and Experimental Research, 31(1), 156-165. PMID: 17207114; DOI: 10.1111/j.1530-0277.2006.00277.x.
• Rangaswamy M, Jones KA, Porjesz B, Chorlian DB, Padmanabhapillai A, Kamarajan C, Kuperman S, Rohrbaugh J, O'Connor SJ, Bauer LO, Schuckit MA, Begleiter H (2007) Delta and theta oscillations as risk markers in adolescent offspring of alcoholics. International Journal of Psychophysiology, 63(1), 3-15. PMID: 17129626; PMCID: PMC2020838; DOI: 10.1016/j.ijpsycho.2006.10.003.
• Jones KA, Porjesz B, Chorlian D, Rangaswamy M, Kamarajan C, Padmanabhapillai A, Stimus A, Begleiter H (2006) S-transform time-frequency analysis of P300 reveals deficits in individuals diagnosed with alcoholism. Clinical Neurophysiology, 117(10), 2128-2143. PMID: 16926113; DOI: 10.1016/j.clinph.2006.02.028.
• Kamarajan C, Porjesz B, Jones K, Chorlian D, Padmanabhapillai A, Rangaswamy M, Stimus A, Begleiter H (2006) Event-related oscillations in offspring of alcoholics: neurocognitive disinhibition as a risk for alcoholism. Biological Psychiatry, 59(7), 625-634. PMID: 16213472; PMCID: PMC3766847; DOI: 10.1016/j.biopsych.2005.08.017.
• Padmanabhapillai A, Porjesz B, Ranganathan M, Jones KA, Chorlian DB, Tang Y, Kamarajan C, Rangaswamy M, Stimus A, Begleiter H (2006) Suppression of early evoked gamma band response in male alcoholics during a visual oddball task. International Journal of Psychophysiology, 60(1), 15-26. PMID: 16019097; DOI: 10.1016/j.ijpsycho.2005.03.026.
• Padmanabhapillai A, Tang Y, Ranganathan M, Rangaswamy M, Jones KA, Chorlian DB, Kamarajan C, Stimus A, Kuperman S, Rohrbaugh J, O'Connor SJ, Bauer LO, Schuckit MA, Begleiter H, Porjesz B (2006) Evoked gamma band response in male adolescent subjects at high risk for alcoholism during a visual oddball task. International Journal of Psychophysiology, 62(2), 262-271. PMID: 16887227; DOI: 10.1016/j.ijpsycho.2006.05.012.
• Kamarajan C, Porjesz B, Jones KA, Choi K, Chorlian DB, Padmanabhapillai A, Rangaswamy M, Stimus AT, Begleiter H (2005) Alcoholism is a disinhibitory disorder: neurophysiological evidence from a Go/No-Go task. Biological Psychology, 69(3), 353-373. PMID: 15925035; PMCID: PMC3758477; DOI: 10.1016/j.biopsycho.2004.08.004.
• Kamarajan C, Porjesz B, Jones KA, Chorlian DB, Padmanabhapillai A, Rangaswamy M, Stimus AT, Begleiter H (2005) Spatial-anatomical mapping of NoGo-P3 in the offspring of alcoholics: evidence of cognitive and neural disinhibition as a risk for alcoholism. Clinical Neurophysiology, 116(5), 1049-1061. PMID: 15826845; PMCID: PMC3785104; DOI: 10.1016/j.clinph.2004.12.015.
• Porjesz B, Rangaswamy M, Kamarajan C, Jones KA, Padmanabhapillai A, Begleiter H (2005) The utility of neurophysiological markers in the study of alcoholism. Clinical Neurophysiology, 116(5), 993-1018. PMID: 15826840; DOI: 10.1016/j.clinph.2004.12.016.
• Kamarajan C, Porjesz B, Jones KA, Choi K, Chorlian DB, Padmanabhapillai A, Rangaswamy M, Stimus AT, Begleiter H (2004) The role of brain oscillations as functional correlates of cognitive systems: a study of frontal inhibitory control in alcoholism. International Journal of Psychophysiology, 51(2), 155-180. PMID: 14693365; PMCID: PMC3766846; DOI: 10.1016/j.ijpsycho.2003.09.004.
• Mukundan CR, Ramachandra S, Singh N, Sharma M, Kamarajan C (1999) Brain mechanisms of hypnosis: P300 studies. Indian Journal of Clinical Psychology, 26(1), 13-23. LINK: https://www.researchgate.net/publication/235624403_Brain_mechanisms_of_hypnosis_P300_studies.

CURRENT FUNDING SUPPORT

(i) R01-AA028848: Bernice Porjesz (PI), Chella Kamarajan (MPI), Jacquelyn Meyers (MPI), Ashwini Pandey (MPI) 09/20/2021 – 06/30/2026 [Sponsor: NIAAA]

• Title: Brain Function and Neurogenomic influences on AUD risk and resilience
• Goals: To understand neurocognitive and genomic factors underlying risk and consequences of alcohol use disorder.
• Role: Co-Principal Investigator
• Funding Period: 09/20/2021 – 06/30/2026

 

(ii) U10-AA008401: Bernice Porjesz (National PI) 09/05/2019 – 08/31/2024 [Sponsor: NIAAA & NIDA]

• Title: Collaborative Study on the Genetics of Alcoholism (COGA) Co-funding by NIAAA and NIDA
• Goals: To elucidate genetic, familial, environmental factors and their interactions in the cause, course, symptoms, and manifestations of alcoholism and other co-occurring psychiatric disorders
• Role: Co-Investigator
• Funding Period: 09/05/2019 – 08/31/2024