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SUNY Downstate Health Sciences University

Division of Transplantation


Rejection of the transplanted kidney is not unusual and can usually be treated and reversed on an out-patient basis by adjusting your medications.

Rejection episodes are most likely to happen within the first three (3) months after transplant. For this reason, your doses of anti-rejection medications are at their highest during this period. These doses will be slowly tapered or lowered during the first several months after transplant.

Major rejection episodes may require hospitalization for more extensive testing which may include a biopsy of your kidney and intensive anti-rejection therapy.

Rejection episodes are usually reversible with treatment.

Signs and Symptoms of Rejection

Notify the Transplant Nurse Practitioner or doctor immediately if you develop any of the following symptoms:

  • Fever of 101
  • No urine output
  • Redness, swelling or drainage from your incision
  • Repeated vomiting or diarrhea

Please note that while any of these may be a sign of rejection, they may also be a sign of something else so do not be alarmed. Call us and we will advise you.