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SUNY Downstate Health Sciences University

Department of Pathology


Raavi Gupta, MD

Raavi Gupta, MD

Associate Professor

Department of Pathology
Division of Surgical Pathology and Hematopathology

Tel: (718) 270-1673 • Fax: (718) 270-3331



Office location: A2-406A

Research or Clinical Interest Summary

My research interests include hematopoietic neoplasms including myelodysplastic syndrome and biology of cancer in different ethnic populations.

Research Support:

Principal Investigator: R Gupta, MD
miR Diagnostics
09/10/2018- 09/09/2019
Development of new screening tests for diagnosing urological cancer through ‘liquid biopsies’, especially focusing on the African American patients, who have not been adequately represented in other test development studies

Co-Investigator: R. Gupta, M.D.
NIH - P20
Feasibility studies to build collaborative partnerships in cancer research to study racial/ethnic differences in GI cancer biology.

Principal Investigator at Downstate: R Gupta, M.D.
NIH Health Disparities Seed Funding Program
2019 - 2020
Racial Disparities in TNBC: Role of Clusters of Enhancers and associated lncRNAs
In a joint Albany and Downstate effort we are studying super-enhancers and long noncoding RNAs that drive aberrant activation of oncogenic pathways in African American women. The knowledge of these genetic risk factors will enhance our understanding of the biology of breast cancer in African American women and help identify genes that could be used to develop targeted therapies.

Book Chapter

Gupta, R., Nowakowski, M. & Haseeb, M.A. 2015. Human protozoal infections and their potential for causing neoplasms. In M.R. Shurin, Y. Thanavaka & N. Ismail (eds), Infection and Cancer: Bi-Drectional Interactions.. Springer, Berlin. pp. 75-91.

  • Momeni-Boroujeni, A., Yousefi, E.,Haseeb, M.A., Gupta, R. Computer - assisted Diagnosis of Breast Cancer by Cell Network Matrix Extraction and Multilayer Perceptron Analysis. 2020. Annals of Clinical & Laboratory Science. 50 (2) In Press.
  • Xia, R., Momeni-Boroujeni, A., Shea, S., Pan, Y, Agrawal, R., Yousefi, E., Haseeb, M.A,. Gupta, R. 2019. Diagnosis of Liver Neoplasms by Computational and Statistical Image Analysis. Gastroenterology Research. In Press.
  • Isaac, J., Pereda, M., Gupta, R., Zhang, Y., Jyakumar, R., Miller, S. 2018. Massive Splenic Infarction in a Child with Sickle Cell Disease on Chronic Transfusion Therapy. Journal of Pediatric Hematology/Oncology 41(2). PMID: 30499910 DOI: 10.1097/MPH.0000000000001356
  • Laskar, D., Rose, M., Gupta, R., Tanowitz, H., Haseeb, MA. 2018. Monoclonal Gammopathy of Undetermined Significance is Associated with Loa loa Infection. American Journal of Tropical Medicine & Hygiene. [Epub ahead of print]. PMID: 30203743. doi: 10.4269/ajtmh.18-0351.
  • Sadaf, S., Schwarz, S., Anderson, V., Gupta, R., Heidarian, A., Rabinovitz, S. 2018. Pediatric Helicobacter pylori gastropathy demonstrates a unique pattern of gastric foveolar hyperplasia. Helicobacter. 23(3):e12487. doi: 10.1111/hel.12487.
  • Mascareno, E., Gupta, R., Martello, LA., Dhar-Mascareno, M., Salciccioli, L., Beckles, D., Walsh, MG.,  Machado, FS., Tanowitz, HB., Haseeb,M.A. 2017. Rapidly progressive course of Trypanosoma cruzi infection in mice heterozygous for hexamethylene bis-acetamide inducible-1 (Hexim-1) gene. Microbes & Infection. 20(1):25-36. doi: 10.1016. PMID: 28951318.
  • Gupta, R., Haseeb, M.A. 2017. Path to the future: Join hands with your fellow pathologists - make your community stronger. Archives of Pathology and Laboratory Medicine.141(12):1602-1603. doi: 10.5858. PMID: 29189066.
  • Azhar, M., Shafique, K., Oza, T., M.A. Haseeb., Gupta, R. Bilateral thyroid-type struma ovarii in a postmenopausal patient: A case report and review of literature. 2017. Journal of Clinical Gynecology and Obstetrics. [in press].
  • Shah S, Gupta R, Shinder R. Orbital Plasmacytoma in a Young Man with Multiple Myeloma. 2017. J Clin Exp Ophthalmol. [in press]
  • Gottesman, S., Yousefi, E., Gupta, R. Hydrophilic polymer vasculopathy with coinciding pseudoxanthoma elasticum-like changes in an amputated toe. 2017. Journal of Cutaneous Pathology. doi:10.1111/cup.12889.
  • Arora, S., Levitan, D; Regmi, N; Sidhu, G; Gupta, R; Nicastri, A; Saggi, SJ; Braverman, A. Cryoglobulinemia in a patient with Chronic Lymphocytic Leukemia (CLL) - A case report and review of literature of renal involvement in CLL. 2016. Blood Cells, Molecules and Diseases. 60: 7-11. doi:10.1016.
  • Silverman, N., Lanjewar, S, Gupta, R., Shinder, R. 2016. IgG4-related disease of the punctum and canaliculus. Ophthalmic Plastic and Reconstructive Surgery. PMID: 26866331 [Epub ahead of print]
  • Ayoub, I., Babinska, A., Gupta, R., Oh, M., Salifu, M. 2015. Colon necrosis due to sodium polystyrene sulfonate (SPS) with and without sorbitol: An experimental study in rats. PLoS One. 28;10(9). PMID: 26413782.
  • Gupta, R., Gorsky, M., Henderson, T., & M.A. Haseeb. 2015. Clinical course of unilateral Acanthamoeba keratitis in a cosmetic contact lens wearer. Annals of Clinical & Laboratory Science, 45: 366-370. PMID: 26116606
  • Loizou, D., Enav, B., Komlodi-Pasztor, E., Hider, P., Kim-Chang, J., Noonan, L., Taber, T., Kaushal, S., Limgala, R., Brown, M., Gupta, R., Balba, N., Goker-Alpan, O., Khojah, A. & Alpan, O. 2015. The effect of omalizumab treatment on allergic tissue inflammation and clinical outcomes in patients with eosinophilic esophagitis: An open label, single arm study. PLoS One, 10 (3). PMID: 25789989
  • Kinneman, L., Molloy, B., Nguyen, V., Loizou, D., Silverman, R., Mensah-Bonsu, N., Enav, B., Johal, J., Plassmeyer, M., Ryherd, M., Austin, L., Limgala, R., Brown, M., Gupta, R., Noonan, L., Hider, P. & Alpan, O. 2014. Diffuse cutaneous mastocytosis, bullous variant, presenting in a six-month-old infant. Journal of Allergy and Clinical Immunology in Practice, 2: 341-342. PMID: 24811027
  • Xi, Q., Wang, H., Heilman, E.R., Walsh, M.G., Haseeb, M.A. & Gupta, R. 2014. Increased expression of enhancer of Zeste homolog 2 (EZH2) differentiates squamous cell carcinoma from normal skin and actinic keratosis. European Journal of Dermatology, 24: 41-45. PMID: 24413452
  • Gill, R., Al-Subu, A., Elitsur, Y., Gupta, R., Treem, W.R., Rabinowitz, S. & Schwarz, S.M. 2014. Eosinophilic esophagitis in two ethnically distinct pediatric populations. Journal of Allergy and Clinical Immunology, 133: 576–577.
  • Martello, L.A., Wadgaonkar, R., Gupta, R., Machado, F.S., Walsh, M.G., Mascareno, E., Tanowitz, H.B. & Haseeb, M.A. 2013. Characterization of Trypanosoma cruzi infectivity, proliferation, and cytokine patterns in gut and pancreatic epithelial cells maintained in vitro. Parasitology Research, 112: 4177-4183. PMID: 24018709.
  • Rets, A., Gupta, R. & Haseeb, M.A. 2013. Determinants of reactivation of inapparent Strongyloides stercoralis infection in patients hospitalized for unrelated admitting diagnosis. European Journal of Gastroenterology and Hepatology, 25: 1279-1285. PMID: 24081104.
  • Huimiao, J., Gupta, R. & Somma, J. 2013. EZH2, a unique marker of malignancy in effusion cytology. Diagnostic Cytopathology, 42: 111-116. PMID: 23636867.
  • Gupta, R., Babb, J.S., Singh, B., Chiriboga, L., Libbys, L., Adams, S. & Demaria, S. 2011. The numbers of FoxP3+ lymphocytes in sentinel lymph nodes of breast cancer patients correlate with primary tumor size but not nodal status. Cancer Investigation, 29: 419-425. PMID: 21649468.
  • Lim, R.P., Tuvia, K., Hajdu, C.H., Losada, M., Gupta, R., Parikh, T., Babb, J.S. & Taouli, B. 2010. Quantification of hepatic iron deposition in patients with liver disease: comparison of chemical shift imaging with single-echo T2-weighted imaging. American Journal of Roentgenology, 194: 1288-1295. PMID: 20410416.
  • Zhang, X., Gupta, R. & Nicastri, A.D. 2010. Bladder adenocarcinoma following gastrocystoplasty. Journal of Pediatric Urology, 6: 525-527. PMID: 2039267.
  • Hyams, E.S., Gupta, R., Melamed, J., Taneja, S.S. & Shah, O. 2009. Renal involvement by chronic myelomonocytic leukemia requiring nephrouretrectomy. Reviews in Urology, 11: 33–37. PMID: 19390673.
  • Gupta, R., Soupir, C.P., Johari, V. & Hasserjian, R.P. 2007. Myelodysplastic syndrome with isolated deletion of chromosome 20q: an indolent disease with minimal morphologic dysplasia and frequent thrombocytopenic presentation. British Journal of Haematology, 139: 265-268. PMID: 17764468.
  • Olack, B., Gupta, R. & Brooks, G.S. 2007. Anaplastic large T-cell lymphoma arising in saline breast implant capsule after tissue expander breast reconstruction. Annals of Plastic Surgery, 59: 56-57. PMID: 17589261.