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SUNY Downstate Health Sciences University

Department of Medicine

Profile

photo of Ellen Ginzler

Ellen M. Ginzler, MD, MPH

Distinguished Teaching Professor of Medicine and Chief of Rheumatology

Tel: (718) 270-1662 • Fax: (718) 270-1562

e-mail: ellen.ginzler@downstate.edu

Education:
  • Bryn Mawr College, Bryn Mawr, Pennsylvania, AB 1965, Magna Cum Laude with Honors
  • Case Western Reserve University School of Medicine, Cleveland, Ohio, MD 1969
  • Yale University School of Epidemiology and Public Health, New Haven, Connecticut, MPH 1983
Post-graduate Training:
  • Straight Medical Internship, Kings County Hospital, Brooklyn, NY, 7/69-6/70
  • Resident in Medicine, Kings County Hospital, 7/70-6/71
  • Senior Resident in Medicine, Bellevue Hospital, New York, NY, 7/71-6/72
  • Fellow in Rheumatology, SUNY Downstate Medical Center, 7/72-6/74
Career / Research Interests:
  • Epidemiology of systemic lupus erythematosus, particularly with regard to outcome measures and sociodemographic influences
  • Accelerated atherosclerosis in rheumatic disease
  • Clinical course and treatment of systemic lupus erythematosus, including randomized clinical trials
  • Ginzler EM, Nicastri AD, Chen C-K, et al: Progression of mesangial and focal to diffuse lupus nephritis. New Engl J Med 291:693-696, 1974
  • Gladman D, Ginzler E, Goldsmith C, Fortin P, Liang M, Urowitz M, Bacon P, Bombardieri S, Hanly J, Hay E, Isenberg D, Jones J, Nived O, Petri M, Richter M, Sanchez-Guerrero J, Snaith M, Sturfelt G, Symmons D: The development and initial validation of the SLICC/ACR damage index for SLE. Arthritis Rheum 39:363-369, 1996.
  • Ginzler EM, Dooley MA, Aranow C, Kim MY, Buyon J, Merrill JT, et al: Mycophenolate mofetil or intravenous cyclophosphamide for lupus nephritis. New Engl J Med 353: 2219-2228, 2005.
  • Ginzler EM, Dvorkina 0: Infections in systemic lupus erythematosus. In Dubois' Lupus Erythematosus, 7th edition, ed. DJ Wallace, BH Hahn. Lippincott, Williams & Wilkins, Philadelphia, PA, 2007.
  • Furie R, Stohl W, Ginzler EM, et al. Biologic activity and safety of belimumab, a neutralizing anti-B-lymphocyte stimulator (BLyS) monoclonal antibody: phase I trial in patients with systemic lupus erythematosus. Arthritis Research & Therapy 2008; 10:R109
  • Appel GB, Contreras G, Dooley MA, Ginzler EM, et al. Mycophenolate mofetil versus cyclophosphamide for induction treatment of lupus nephritis. A randomized trial. J Am Soc Nephrol. 2009:20:1103-1112
  • Ginzler E, Wofsy D, Isenberg D, et al. Nonrenal activity following mycophenolate mofetil or intravenous cyclophosphamide as induction treatment for lupus nephritis. Arthritis Rheum 2010; 62:211-221
  • Furie RA, Petri AM, Wallace DJ, Ginzler EM, et al. Novel evidence-based systemic lupus erythematosus responder index. Arthritis Care & Res 2009; 61:1143-1151
  • Isenberg D, Appel GB, Contreras G, Dooley MA, Ginzler EM et al. Influence of race/ethnicity on response to lupus nephritis treatment: the ALMS study. Rheumatology 2010; 49:128-140
  • Ginzler E, Wofsy D, Isenberg D, et al. Nonrenal activity following mycophenolate mofetil or intravenous cyclophosphamide as induction treatment for lupus nephritis. Arthritis Rheum 2010; 62:211-221
  • Radhakrishnan J, Moutzouris D-A, Ginzler EM, et al. Mycophenolate mofetil and intravenous cyclophosphamide are similar as induction therapy for class V lupus nephritis. Kidney Int 2010; 77:152-160
  • Dooley AM, Jayne D, Ginzler EM, et al. Mycophenolate versus azathioprine as maintenance therapy for lupus nephritis. New Engl J Med 2011; 365:1886-1895
  • Ginzler EM, Wax S, Rajeswaran A, et al. Atacicept in combination with MMF and corticosteroids in lupus nephritis: results of a prematurely terminated trial. Arthritis Res & Ther 2012; 14:R33.
  • Ginzler EM, Wallace DJ, Merrill JT, et al. Disease control and safety of belimumab plus standard therapy over 7 years in patients with systemic lupus erythematosus. J Rheumatol 2014; 41:300-309.

  • Volumes Edited:
  • Rheumatic Disease Clinics of North America. Systemic Lupus Erythematosus, Volume 36, February 2010. Ginzler EM, ed.
  • Rheumatic Disease Clinics of North America. Systemic Lupus Erythematosus, Volume 40, August 2014, Ginzler EM and Dooley MA, eds.