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SUNY Downstate Health Sciences University

Henri Begleiter Neurodynamics Laboratory

Collaborative Study on the Genetics of Alcoholism Data Articles

Reviewed articles with supplied COGA data (SAGE articles are marked with ***)

A complete list of all publications with downloaded COGA data as a PDF-file (last change 2019-8-29)

 

Number of published articles with data requested from COGA:

 

1999

2006

2007

2008

2009

2010

2011

1

4

4

7

1

7

11

2012

2013

2014

2015

2016

2017

2018

16

23

21

21

10

10

4

2019

           

1

           

Sum

           

141

           

The downloadable PDF files are for you personal, scientific use only!

 

2019

Mintz CM, Hartz SM, Borodovsky JT, Bierut LJ, Grucza RA (2019). Changes in associations of prescription opioid use disorder and illegal behaviors among adults in the United States from 2002 to 20. Addiction (Abingdon, England). PMID: 31033084.

2018

Cabana-Dominguez J, Arenas C, Cormand B, Fernandez-Castillo N (2018) MiR-9, miR-153 and miR-124 are down-regulated by acute exposure to cocaine in a dopaminergic cell model and may contribute to cocaine dependence. Translational Psychiatry 8(1):173. PMID: 30166527.

Donvito G, Muldoon PP, Jackson KJ, Ahmad U, Zaveri NT, McIntosh JM, Chen X, Lichtman AH, Damaj MI (2018). Neuronal nicotinic acetylcholine receptors mediate (9) -THC dependence: Mouse and human studies. Addiction Biology [Epub ahead of print]. PMID: 30378732.

Pineda-Cirera L, Cabana-Dominguez J, Roncero C, Cozar M, Grau-Lopez L, Abad AC, Martinez-Luna N, Robles-Martinez M, Sanchez-Mora C, Ramos-Quiroga JA, Casas M, Ribases M, Fernandez-Castillo N, Cormand B (2018) Evaluation of previous substance dependence genome-wide significant findings in a Spanish sample. Drug and Alcohol Dependence, 187:358-362. PMID: 29715653. (PDF file)

Sulovari A, Liu Z, Zhu Z, Li D (2018) Genome-wide meta-analysis of copy number variations with alcohol dependence. The Pharmacogenomics Journal, 18(3):398-405. PMID: 28696413. (PDF file)

2017

Jensen KP, Smith AH, Herman AI, Farrer LA, Kranzler HR, Sofuoglu M, Gelernter J (2017). A protocadherin gene cluster regulatory variant is associated with nicotine withdrawal and the urge to smoke. Mol Psychiatry, 22(2):242-249. PMID: 27067016. PMC5390815. (PDF file)

Liu D, Zhang H (2018) Residuals and Diagnostics for Ordinal Regression Models: A Surrogate Approach. Journal of the American Statistical Association, 113(522):845-854. PMID: 30220754. (PDF file)

Martinez-Rivera A, Hao J, Tropea TF, Giordano TP, Kosovsky M, Rice RC, Lee A, Huganir RL, Striessnig J, Addy NA, Han S, Rajadhyaksha AM (2017). Enhancing VTA Cav1.3 L-type Ca(2+) channel activity promotes cocaine and mood-related behaviors via overlapping AMPA receptor mechanisms in the nucleus accumbens. Mol Psychiatry 22(12):1735-1745. PMID: 28194001.

Melroy-Greif WE, Simonson MA, Corley RP, Lutz SM, Hokanson JE, Ehringer MA (2017) Examination of the Involvement of Cholinergic-Associated Genes in Nicotine Behaviors in European and African Americans. Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco, 19(4):417-425. PMID: 27613895. (PDF file)

Polimanti R, Zhang H, Smith AH, Zhao H, Farrer LA, Kranzler HR, Gelernter J (2017). Genome-wide association study of body mass index in subjects with alcohol dependence. Addiction Biology, 22(2):535-549. PMID: 26458734.

Wang J, Talluri R, Shete S (2017). Selection of X-chromosome Inactivation Model. Cancer informatics, 16: [Epub]. PMID: 29308008.

Wang M, Huang J, Liu Y, Ma L, Potash JB, Han S (2017) COMBAT: A Combined Association Test for Genes Using Summary Statistics. Genetics, 207(3):883-891. PMID: 28878002. (PDF file)

Yang HC, Chen IC, Tsay YC, Li ZR, Chen CH, Hwu HG, Chen CH (2017) Using an Event-History with Risk-Free Model to Study the Genetics of Alcoholism. Scientific reports, 7(1):1975. PMID: 28512340. (PDF file)

Yang J, Li MD (2014) Association and interaction analyses of 5-HT3 receptor and serotonin transporter genes with alcohol, cocaine, and nicotine dependence using the SAGE data. Human genetics, 133(7):905-18. PMID: 24590108. (PDF file)

 Zollanvari A, Alterovitz G (2017) SNP by SNP by environment interaction network of alcoholism. BMC systems biology, 11(Suppl 3):19. PMID: 28361705. (PDF file)

2016

Bidwell LC, Palmer RH, Brick L, McGeary JE, Knopik VS (2016) Genome-wide single nucleotide polymorphism heritability of nicotine dependence as a multidimensional phenotype. Psychological medicine, 46(10):2059-69. PMID: 27052577. (PDF file)

Clarke TK, Smith AH, Gelernter J, Kranzler HR, Farrer LA, Hall LS, Fernandez-Pujals AM, MacIntyre DJ, Smith BH, Hocking LJ, Padmanabhan S, Hayward C, Thomson PA, Porteous DJ, Deary IJ, McIntosh AM (2016)Polygenic risk for alcohol dependence associates with alcohol consumption, cognitive function and social deprivation in a population-based cohort. Addiction biology, 21(2):469-80. PMID: 25865819. (PDF file)

Li M, Wei CS, Wen YL, Wang T, Lu Q (2016) Detecting Gene-Gene interactions associated with multiple complex traits with U-statistics. Current Genomics 17(5):403-415. (PDF file)

Melroy-Greif WE, Vadasz C, Kamens HM, McQueen MB, Corley RP, Stallings MC, Hopfer CJ, Krauter KS, Brown SA, Hewitt JK, Ehringer MA (2016) Test for association of common variants in GRM7 with alcohol consumption. Alcohol (Fayetteville, NY), 55:43-50. PMID: 27788777. (PDF file)

Owasu D, Pan Y, Xie C, Harirforoosh S, Wang KS (2016) Polymorphisms in PDLIM5 gene are associated with alcohol dependence, type 2 diabetes, and hypertension. Journal of Psychiatric Research 84:27-34. (PDF file)

Palmer RH, Nugent NR, Brick LA, Bidwell CL, McGeary JE, Keller MC, Knopik VS (2016) Evidence of Shared Genome-Wide Additive Genetic Effects on Interpersonal Trauma Exposure and Generalized Vulnerability to Drug Dependence in a Population of Substance Users. Journal of Traumatic Stress 29:197-204. PMID: 27214850. (PDF file)

Perry BL (2016) Gendering Genetics: Biological Contingencies in the Protective Effects of Social Integration for Men and Women. American Journal of Sociology 121:1655-1696. (PDF file)

***Sherva R, Wang Q, Kranzler H, Zhao H, Koesterer R, Herman A, Farrer LA, Gelernter J (2016) Genome-wide association study of cannabis dependence severity, novel risk variants, and shared genetic risks. JAMA Psychiatry 73(5):472-480. PMIC4974817. (PDF file)

Uddin M, Pellecchia G, Thiruvahindrapuram B, D'Abate L, Merico D, Chan A, Zarrei M, Tammimies K, Walker S, Gazzellone MJ, Nalpathamkalam T, Yuen RK, Devriendt K, Mathonnet G, Lemyre E, Nizard S, Shago M, Joseph-George Am, Noor A, Carter MT, Yoon G, Kannu P, Tihy F, Thorland EC, Marshall CR, Buchanan JA, Speevak M, Stavropoulos DJ, Scherer SW (2016) Indexing effects of copy number variation on genes involved in developmental delay. Scientific Reports 6:28663. PMID: 27363808. PMC4929460.

Zhao J, Zhang H (2016) Modeling Multiple Responses via Bootstrapping Margins with an Application to Genetic Association Testing. Statistics and its interface, 9(1):47-56. PMID: 26543519.

2015

de Leeuw C, Goudriaan A, Smit AB, Yu D, Mathews CA, Scharf JM, Verheijen MH, Posthuma D (2015)
Involvement of astrocyte metabolic coupling in Tourette syndrome pathogenesis.
European Journal of Human Genetics 23:1519-1522. PMID: 25735483. PMC4613465. (PDF file)

*** Derringer J, Corley RP, Haberstick BC, Young SE, Demmitt BA, Howrigan DP, Kirkpatrick RM, Iacono WG, McGue M, Keller MC, Brown S, Tapert S, Hopfer CJ, Stallings MC, Crowley TJ, Rhee SH, Krauter K, Hewitt JK, McQueen MB (2015)
Genome-Wide Association Study of Behavioral Disinhibition in a Selected Adolescent Sample.
Behavior Genetics 45(4):375-381. PMID: 25637581. (PDF file)

Gelernter J, Kranzler HR, Sherva R, Almasy L, Herman AI, Koesterer R, Zhao H, Farrer LA (2015) Genome-wide association study of nicotine dependence in American populations: identification of novel risk loci in both African-Americans and European-Americans. Biological psychiatry, 77(5):493-503. PMID: 25555482. (PDF file)

*** Li D, Zhao H, Kranzler HR, Li MD, Jensen KP, Zayats T, Farrer LA, Gelernter J (2015)
Genome-wide association study of copy number variations (CNVs) with opioid dependence.
Neuropsychopharmacology 40(4):1016-1026.PMID: 25345593. PMCID: PMC4330517 (PDF file)

*** Muldoon PP, Chen J, Harenza JL, Abdullah RA, Sim-Selley LJ, Cravatt BF, Miles MF, Chen X, Lichtman AH, Damaj MI (2015)
Inhibition of monoacylglycerol lipase reduces nicotine withdrawal.
British Journal of Pharmacology 172(3):869-882. PMID: 25258021. PMCID: PMC4301695 (PDF file)

*** Palmer RH, Brick L, Nugent NR, Bidwell LC, McGeary JE, Knopik VS, Keller MC (2015)
Examining the role of common genetic variants on alcohol, tobacco, cannabis and illicit drug dependence: genetics of vulnerability to drug dependence.
Addiction 110(3):530-537. PMID: 25424661. PMCID: PMC4329043 (PDF file)

*** Palmer RH, McGeary JE, Heath AC, Keller MC, Brick LA, Knopik VS (2015)
Shared Additive Genetic Influences on DSM-IV Criteria for Alcohol Dependence in Subjects of European Ancestry.
Addiction. PMID: 26211938. (PDF file)

Pan W, Chen YM, Wei P (2015)
Testing for polygenic effects in genome-wide association studies.
Genetic epidemiology 39:306-316. PMID: 25847094. PMC4406854. (PDF file)

Polimanti R, Yang C, Zhao H, Gelernter J (2015)
Dissecting ancestry genomic background in substance dependence genome-wide association studies.
Pharmacogenomics 16:1487-1498. PMID: 26267224. PMC4632979. (PDF file)

***Repunte-Canonigo V, Herman MA, Kawamura T, Kranzler HR, Sherva R, Gelernter J, Farrer LA, Roberto M, Sanna PP (2015)
Nf1 regulates alcohol dependence-associated excessive drinking and gamma-aminobutyric acid release in the central amygdala in mice and is associated with alcohol dependence in humans.
Biological Psychiatry 77:870-879. PMID: 25483400. PMC: 4428692. (PDF file)

Sadeh N, Wolf EJ, Logue MW, Lusk J, Hayes JP, McGlinchey RE, Milberg WP, Stone A, Schichman SA, Miller MW (2015)
Polygenic Risk for Externalizing Psychopathology and Executive Dysfunction in Trauma-Exposed Veterans.
Clinical Psychological Science. (PDF file)

***Suchankova P, Yan J, Schwandt ML, Stangl BL, Caparelli EC, Momenan R, Jerlhag E, Engel JA, Hodgkinson CA, Egli M, Lopez MF, Becker HC, Goldman D, Heilig M, Ramchandani VA, Leggio L (2015)
The glucagon-like peptide-1 receptor as a potential treatment target in alcohol use disorder: evidence from human genetic association studies and a mouse model of alcohol dependence.
Translational psychiatry 5:e583. PMID: 26080318. PMC4490279. (PDF file)

Sun J, Kranzler HR, Bi J (2015)
An Effective Method to Identify Heritable Components from Multivariate Phenotypes.
PloS one 10:e0144418. PMID: 26658140. PMC4678282. (PDF file)

Talluri R, Shete S (2015) Evaluating methods for modeling epistasis networks with application to head and neck cancer. Cancer informatics, 14(Suppl 2):17-23. PMID: 25733798. (PDF file)

***Wang KS, Zuo L, Pan Y, Xie C, Luo X (2015)
Genetic variants in the CPNE5 gene are associated with alcohol dependence and obesity in Caucasian populations.
Journal of psychiatric research 71:1-7. PMID: 26522866. (PDF file)

Xu K, Kranzler HR, Sherva R, Sartor CE, Almasy L, Koesterer R, Zhao H, Farrer LA, Gelernter J (2015) Genomewide Association Study for Maximum Number of Alcoholic Drinks in European Americans and African Americans. Alcoholism, Clinical and Experimental Research, 39(7):1137-47. PMID: 26036284. (PDF file)

*** Yu D, Mathews CA, Scharf JM, Neale BM, Davis LK, Gamazon ER, Derks EM, Evans P, Edlund CK, Crane J, Fagerness JA, Osiecki L, Gallagher P, Gerber G, Haddad S, Illmann C, McGrath LM, Mayerfeld C, Arepalli S, Barlassina C, Barr CL, Bellodi L, Benarroch F, Berrió GB, Bienvenu OJ, Black DW, Bloch MH, Brentani H, Bruun RD, Budman CL, Camarena B, Campbell DD, Cappi C, Silgado JC, Cavallini MC, Chavira DA, Chouinard S, Cook EH, Cookson MR, Coric V, Cullen B, Cusi D, Delorme R, Denys D, Dion Y, Eapen V, Egberts K, Falkai P, Fernandez T, Fournier E, Garrido H, Geller D, Gilbert DL, Girard SL, Grabe HJ, Grados MA, Greenberg BD, Gross-Tsur V, Grünblatt E, Hardy J, Heiman GA, Hemmings SM, Herrera LD, Hezel DM, Hoekstra PJ, Jankovic J, Kennedy JL, King RA, Konkashbaev AI, Kremeyer B, Kurlan R, Lanzagorta N, Leboyer M, Leckman JF, Lennertz L, Liu C, Lochner C, Lowe TL, Lupoli S, Macciardi F, Maier W, Manunta P, Marconi M, McCracken JT, Mesa Restrepo SC, Moessner R, Moorjani P, Morgan J, Muller H, Murphy DL, Naarden AL, Nurmi E, Ochoa WC, Ophoff RA, Pakstis AJ, Pato MT, Pato CN, Piacentini J, Pittenger C, Pollak Y, Rauch SL, Renner T, Reus VI, Richter MA, Riddle MA, Robertson MM, Romero R, Rosário MC, Rosenberg D, Ruhrmann S, Sabatti C, Salvi E, Sampaio AS, Samuels J, Sandor P, Service SK, Sheppard B, Singer HS, Smit JH, Stein DJ, Strengman E, Tischfield JA, Turiel M, Valencia Duarte AV, Vallada H, Veenstra-VanderWeele J, Walitza S, Wang Y, Weale M, Weiss R, Wendland JR, Westenberg HG, Shugart YY, Hounie AG, Miguel EC, Nicolini H, Wagner M, Ruiz-Linares A, Cath DC, McMahon W, Posthuma D, Oostra BA, Nestadt G, Rouleau GA, Purcell S, Jenike MA, Heutink P, Hanna GL, Conti DV, Arnold PD, Freimer NB, Stewart SE, Knowles JA, Cox NJ, Pauls DL. (2015)
Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette’s syndrome and OCD.
American Journal of Psychiatry 172(1):82-93. PMCID: PMC4282594 (PDF file)

*** Zhao J, and Zhang H (2016)
Modeling Multiple Responses via Bootstrapping Margins with an Application to Genetic Association Testing.
Statistics and its interface 9:47-56. PMID: 26543519. PMCID: PMC4629876. (PDF file)

*** Zuo L, Tan Y, Zhang X, Wang X, Krystal J, Tabakoff B, Zhong C, Luo X (2015)
A New Genomewide Association Meta-Analysis of Alcohol Dependence.
Alcoholism, Clinical and Experimental Research 39(8):1388-1395. PMID: 26173551. (PDF file)

*** Zuo L, Zhang CK, Sayward FG, Cheung KH, Wang K, Krystal JH, Zhao H, Luo X (2015)
Gene-based and pathway-based genome-wide association study of alcohol dependence.
Shanghai Arch Psychiatry 27(2):111-118. PMID: 26120261. (PDF file)

Zuo L, Saba L, Lin X, Tan Y, Wang K, Krystal JH, Tabakoff B, Luo X (2015)
Significant association between rare IPO11-HTR1A variants and attention deficit hyperactivity disorder in Caucasians.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 168:544-556. PMID: 26079129. PMC4851708. (PDF file)

2014

*** Cao, J., Liu, X., Han, S., Zhang, C.K., Liu, Z., and Li, D. (2014).
Association of the HTR2A gene with alcohol and heroin abuse.
Human Genetics 133(3):357-365. PMID: 24178752. (PDF file)

*** Chen, G.B., Liu, N., Klimentidis, Y.C., Zhu, X., Zhi, D., Wang, X., and Lou, X.Y. (2014)
A unified GMDR method for detecting gene-gene interactions in family and unrelated samples with application to nicotine dependence.
Human Genetics 133(2):139-150. PMCID: PMC3947150 (PDF file)

Fenz, Z. (2014).
A generalized quasi-likelihood scoring approach for simultaneously testing the genetic association of multiple traits.
Journal of the Royal Statistical Society: Series C (Applied Statistics) 63(3):483-498. (PDF file)

Gelernter J, Kranzler HR, Sherva R, Almasy L, Koesterer R, Smith AH, Anton R, Preuss UW, Ridinger M, Rujescu D, Wodarz N, Zill P, Zhao H, Farrer LA (2014) Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci. Mol Psychiatry, 19(1):41-9. PMID: 24166409. (PDF file)

Gelernter J, Kranzler HR, Sherva R, Koesterer R, Almasy L, Zhao H, Farrer LA (2014) Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways. Biological psychiatry, 76(1):66-74. PMID: 24143882. (PDF file)

Gelernter J, Sherva R, Koesterer R, Almasy L, Zhao H, Kranzler HR, Farrer L (2014) Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene. Mol Psychiatry, 19(6):717-23. PMID: 23958962. (PDF file)


Hsieh, T.-J., Chang, S.-H., and Tai, J.J. (2014).
A family-based robust multivariate association test using maximum statistic.
Annals of Human Genetics 78(2):117-128. PMID: 24571230. (PDF file)

*** Jiang, Y., Li, N., and Zhang, H.P. (2014)
Identifying Genetic Variants for Addiction via Propensity Score Adjusted Generalized Kendall's Tau.
Journal of the American Statistical Association, 109(507):905-930. PMID: 25382885. PMCID: PMC4219655. (PDF file)

*** Li, D., Sulovari, A., Cheng, C., Zhao, H., Kranzler, H.R., and Gelernter, J. (2014)
Association of gamma-aminobutyric acid A receptor a2 gene (GABRA2) with alcohol use disorder.
Neuropsychopharmacology 39(4):907-918. PMID: 24136292. PMCID: PMC3924525 (PDF file)

*** Li, M., Gardiner, J.C., Breslau, N., Anthony, J.C., and Lu, Q. (2014)
A non-parametric approach for detecting gene-gene interactions associated with age-at-onset.
BMC Genetics 15:79. PMCID: PMC4087128 (PDF file)

Lobach I, Fan R, Manga P (2014) Genotype-based association models of complex diseases to detect gene-gene and gene-environment interactions. Statistics and Its Interface, 7(1):51-60. PMID: 26191336. (PDF file)

*** McGrath LM, Yu D, Marshall C, Davis LK, Thiruvahindrapuram B, Li B, Cappi C, Gerber G, Wolf A, Schroeder FA, Osiecki L, O'Dushlaine C, Kirby A, Illmann C, Haddad S, Gallagher P, Fagerness JA, Barr CL, Bellodi L, Benarroch F, Bienvenu OJ, Black DW, Bloch MH, Bruun RD, Budman CL, Camarena B, Cath DC, Cavallini MC, Chouinard S, Coric V, Cullen B, Delorme R, Denys D, Derks EM, Dion Y, Rosário MC, Eapen V, Evans P, Falkai P, Fernandez TV, Garrido H, Geller D, Grabe HJ, Grados MA, Greenberg BD, Gross-Tsur V, Grünblatt E, Heiman GA, Hemmings SM, Herrera LD, Hounie AG, Jankovic J, Kennedy JL, King RA, Kurlan R, Lanzagorta N, Leboyer M, Leckman JF, Lennertz L, Lochner C, Lowe TL, Lyon GJ, Macciardi F, Maier W, McCracken JT, McMahon W, Murphy DL, Naarden AL, Neale BM, Nurmi E, Pakstis AJ, Pato MT, Pato CN, Piacentini J, Pittenger C, Pollak Y, Reus VI, Richter MA, Riddle M, Robertson MM, Rosenberg D, Rouleau GA, Ruhrmann S, Sampaio AS, Samuels J, Sandor P, Sheppard B, Singer HS, Smit JH, Stein DJ, Tischfield JA, Vallada H, Veenstra-VanderWeele J, Walitza S, Wang Y, Wendland JR, Shugart YY, Miguel EC, Nicolini H, Oostra BA, Moessner R, Wagner M, Ruiz-Linares A, Heutink P, Nestadt G, Freimer N, Petryshen T, Posthuma D, Jenike MA, Cox NJ, Hanna GL, Brentani H, Scherer SW, Arnold PD, Stewart SE, Mathews CA, Knowles JA, Cook EH, Pauls DL, Wang K, and Scharf JM. (2014)
Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study.
Journal of the American Academy of Child & Adolescent Psychiatry 53(8):910-9. PMCID: PMC4218748 (PDF file)

Muldoon PP, Jackson KJ, Perez E, Harenza JL, Molas S, Rais B, Anwar H, Zaveri NT, Maldonado R, Maskos U, McIntosh JM, Dierssen M, Miles MF, Chen X, De Biasi M, Damaj MI (2014) The alpha3beta4* nicotinic ACh receptor subtype mediates physical dependence to morphine: mouse and human studies. British journal of pharmacology, 171(16):3845-57. PMID: 24750073. (PDF file)


*** Song, C. and Zhang, H. (2014)
TARV: tree-based analysis of rare variants identifying risk modifying variants in CTNNA2 and CNTNAP2 for alcohol addiction.
Genetic Epidemiology 38(6):552-559. PMID: 25041903. PMCID: PMC4154634 (PDF file)

*** Taylor, A. and Wang, K.S. (2014)
Association between DPYSL2 gene polymorphisms and alcohol dependence in Caucasian samples.
Journal of Neural Transmission 121(1):105-111. PMID: 23846846. (PDF file)

*** Wang, S.D., van der Vaart, A., Xu, Q., Seneviratne, C., Pomerleau, O.F., Pomerleau, C.S., Payne, T.J., Ma, J.Z., and Li, M.D. (2014).
Significant associations of CHRNA2 and CHRNA6 with nicotine dependence in European American and African American populations.
Human Genetics 133(5):575-586. PMID: 24253422. PMCID: PMC3988215 (PDF file)

*** Wang, J., Yu, R., adn Shete, S. (2014)
X-chromosome genetic association test accounting for X-inactivation, skewed X-inactivation, and escape from X-inactivation.
Genetic Epidemiololgy 38(6):483-93. PMCID: PMC4127090 (PDF file)

Yang, J. and Li, M.D. (2014) Association and interaction analysis of 5-HT3 receptor and serotonin transporter genes with alcohol, cocaine, and nicotine dependence using the SAGE data. Human Genetics 133(7):905-918. PMID: 24590108, PMCID: PMC4055533 (PDF file)

*** Yuan, H. and Dougherty, J.D. (2014) Investigation of Maternal Genotype Effects in Autism by Genome-Wide Association. Autism Research 7(2):245:253 PMID: 24574247. PMCID: PMC3989385 (PDF file)

Zuo L, Lu L, Tan Y, Pan X, Cai Y, Wang X, Hong J, Zhong C, Wang F, Zhang XY, Vanderlinden LA, Tabakoff B, Luo X (2014) Genome-wide association discoveries of alcohol dependence. The American Journal on Addictions, 23(6):526-39. PMID: 25278008. (PDF file)

*** Zuo, L., Wang, K., Wang, G., Pan, X., Zhang, X., Zhang, H., and Luo, X. (2014) Common PTP4A1-PHF3-EYS variants are specific for alcohol dependence. American Journal on Addictions 23(4):411-414. PMID: 24961364. PMCID: PMC4111256 (PDF file)

2013

*** Belsky, D.W., Moffitt, T.E., Baker, T.B., Biddle, A.K., Evans, J.P., Harrington, H., Houts, R., Meier, M., Sugden, K., Williams, B., Poulton, R., and Caspi, A. (2013) Polygenic risk and the developmental progression to heavy, persistent smoking and nicotine dependence: evidence from a 4-decade longitudinal study. JAMA Psychiatry 70(5):534-542 PMID: 23536134 (PDF file)

*** Blaine, S., Claus, E., Harlaar, N., and Hutchison, K. (2013) TACR1 genotypes predict fMRI response to alcohol cues and level of alcohol dependence. Alcoholism: Clinical and Experimental Research 37(Suppl 1):E125-130. PMID: 23078527 (PDF-file)

*** Cui WY, Wang S, Yang J, Yi SG, Yoon D, Kim YJ, Payne TJ, Ma JZ, Park T, Li MD. (2013). Significant association of CHRNB3 variants with nicotine dependence in multiple ethnic populations. Molecular Psychiatry 18:1149-1151 PMID: 23319001 (PDF file)

*** Davis, L.K., Yu, D., Keenan, C.L., Gamazon, E.R., Konkashbaev, A.I., Derks, E.M., Neale, B.M., Yang, J., Lee, S.H., Evans, P., Barr, C.L., Bellodi, L., Benarroch, F., Berrio, G.B., Bienvenu, O.J., Bloch, M.H., Blom, R.M., Bruun, R.D., Budman, C.L., Camarena, B., Campbell, D., Cappi, C., Cardona Silgado, J.C., Cath, D.C., Cavallini, M.C., Chavira, D.A., Chouinard, S., Conti, D.V., Cook, E.H., Coric, V., Cullen, B.A., Deforce, D., Delorme, R., Dion, Y., Edlund, C.K., Egberts, K., Falkai, P., Fernandez, T.V., Gallagher, P.J., Garrido, H., Geller, D., Girard, S.L., Grabe, H.J., Grados, M.A., Greenberg, B.D., Gross-Tsur, V., Haddad, S., Heiman, G.A., Hemmings, S.M., Hounie, A.G., Illmann, C., Jankovic, J., Jenike, M.A., Kennedy, J.L., King, R.A., Kremeyer, B., Kurlan, R., Lanzagorta, N., Leboyer, M., Leckman, J.F., Lennertz, L., Liu, C., Lochner, C., Lowe, T.L., Macciardi, F., McCracken, J.T., McGrath, L.M., Mesa Restrepo, S.C., Moessner, R., Morgan, J., Muller, H., Murphy, D.L., Naarden, A.L., Ochoa, W.C., Ophoff, R.A., Osiecki, L., Pakstis, A.J., Pato, M.T., Pato, C.N., Piacentini, J., Pittenger, C., Pollak, Y., Rauch, S.L., Renner, T.J., Reus, V.I., Richter, M.A., Riddle, M.A., Robertson, M.M., Romero, R., Rosàrio, M.C., Rosenberg, D., Rouleau, G.A., Ruhrmann, S., Ruiz-Linares, A., Sampaio, A.S., Samuels, J., Sandor, P., Sheppard, B., Singer, H.S., Smit, J.H., Stein, D.J., Strengman, E., Tischfield, J.A., Valencia Duarte, A.V., Vallada, H., Van Nieuwerburgh, F., Veenstra-Vanderweele, J., Walitza, S., Wang, Y., Wendland, J.R., Westenberg, H.G., Shugart, Y.Y., Miguel, E.C., McMahon, W., Wagner, M., Nicolini, H., Posthuma, D., Hanna, G.L., Heutink, P., Denys, D., Arnold, P.D., Oostra, B.A., Nestadt, G., Freimer, N.B., Pauls, D.L., Wray, N.R., Stewart, S.E., Mathews, C.A., Knowles, J.A., Cox, N.J., and Scharf, J.M. (2013). Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture. PLoS Genetics 9(10):e1003864. PMCID: PMC381203.

*** Du, M., Prescott, J., Cornelis, M.C., Hankinson, S.E., Giovannucci, E., Kraft, P., and De Vivo, I. (2013) Genetic predisposition to higher body mass index or type 2 diabetes and leukocyte telomere length in the Nurses' Health Study. PLoS One 8(2):e52240. PMID: 23424613 (PDF file)

*** Guo, X., Liu, Z., Wang, X., and Zhang, H. (2013) Genetic association test for multiple traits at gene level. Genetic Epidemiology 37(1):122-129. PMID: 23032486 (PDF file)

Han, S., Yang, B.-Z., Kranzler, H.R., Liu, X., Zhao, H., Farrer, L.A., Boerwinkle, E., Potash, J.B., and Gelernter, J. (2013) Integrating GWASs and human protein interaction networks identifies a gene subnetwork underlying alcohol dependence. The American Journal of Human Genetics 93(6):1027-1034. PMID: 24268660 (PDF file)

*** Liu, Z., Guo, X., Jiang, Y., and Zhang, H. (2013) NCK2 Is significantly associated with opiates addiction in african-origin men. The Scientific World Journal 2013:748979. PMID: 23533358 (PDF file)

Lopes, A.M., Aston, K.I., Thompson, E., Carvalho, F., Gonçalves, J., Huang, N., Matthiesen, R., Noordam, M.J., Quintela, I., Ramu, A., Seabra, C., Wilfert, A.B., Dai, J., Downie, J.M., Fernandes, S., Guo, X., Sha, J., Amorim, A., Barros, A., Carracedo, A., Hu, Z., Hurles, M.E., Moskovtsev, S., Ober, C., Paduch, D.A., Schiffman, J.D., Schlegel, P.N., Sousa, M., Carrell, D.T., and Conrad, D.F. (2013) Human spermatogenic failure purges deleterious mutation load from the autosomes and both sex chromosomes, including the gene DMRT1. PLoS Genetics 9(3):e1003349. PMID: 23555275. PMCID: PMC3605256 (PDF file)

*** Pan, Y., Pan, Y., Luo, X., Liu, X., Wu, L.Y., Zhang, Q., Wang, L., Wang, W., Zuo, L., and Wang, K.S. (2013) Genome-wide association studies of maximum number of drinks. Journal of Psychiatric Research 47(11):1717-1724. PMID: 23953852 (PDF file)

*** Pan, Y., Wang, K.-S., Wang, L., and Wu, L.Y. (2013) Common variants in HLA-DRA gene are associated with alcohol dependence in two caucasian samples.
Journal of Molecular Neuroscience 49(3):574-581. PMID: 22890421 (PDF file)

*** Ray, L.A., Sehl, M., Bujarski, S., Hutchison, K., Blaine, S., and Enoch, M.A. (2013) The CRHR1 gene, trauma exposure, and alcoholism risk: a test of G × E effects. Genes, Brain and Behavior 12(4):361-369. PMID: 23473364 (PDF file)

Scharf JM, Yu D, Mathews CA, Neale BM, Stewart SE, Fagerness JA, Evans P, Gamazon E, Edlund CK, Service SK, Tikhomirov A, Osiecki L, Illmann C, Pluzhnikov A, Konkashbaev A, Davis LK, Han B, Crane J, Moorjani P, Crenshaw AT, Parkin MA, Reus VI, Lowe TL, Rangel-Lugo M, Chouinard S, Dion Y, Girard S, Cath DC, Smit JH, King RA, Fernandez TV, Leckman JF, Kidd KK, Kidd JR, Pakstis AJ, State MW, Herrera LD, Romero R, Fournier E, Sandor P, Barr CL, Phan N, Gross-Tsur V, Benarroch F, Pollak Y, Budman CL, Bruun RD, Erenberg G, Naarden AL, Lee PC, Weiss N, Kremeyer B, Berrio GB, Campbell DD, Cardona Silgado JC, Ochoa WC, Mesa Restrepo SC, Muller H, Valencia Duarte AV, Lyon GJ, Leppert M, Morgan J, Weiss R, Grados MA, Anderson K, Davarya S, Singer H, Walkup J, Jankovic J, Tischfield JA, Heiman GA, Gilbert DL, Hoekstra PJ, Robertson MM, Kurlan R, Liu C, Gibbs JR, Singleton A, Hardy J, Strengman E, Ophoff RA, Wagner M, Moessner R, Mirel DB, Posthuma D, Sabatti C, Eskin E, Conti DV, Knowles JA, Ruiz-Linares A, Rouleau GA, Purcell S, Heutink P, Oostra BA, McMahon WM, Freimer NB, Cox NJ, Pauls DL (2013) Genome-wide association study of Tourette's syndrome. Mol Psychiatry, 18(6):721-8. PMID: 22889924. (PDF file)

*** Stewart SE, Yu D, Scharf JM, Neale BM, Fagerness JA, Mathews CA, Arnold PD, Evans PD, Gamazon ER, Davis LK, Osiecki L, McGrath L, Haddad S, Crane J, Hezel D, Illman C, Mayerfeld C, Konkashbaev A, Liu C, Pluzhnikov A, Tikhomirov A, Edlund CK, Rauch SL, Moessner R, Falkai P, Maier W, Ruhrmann S, Grabe HJ, Lennertz L, Wagner M, Bellodi L, Cavallini MC, Richter MA, Cook EH Jr, Kennedy JL, Rosenberg D, Stein DJ, Hemmings SM, Lochner C, Azzam A, Chavira DA, Fournier E, Garrido H, Sheppard B, Umaña P, Murphy DL, Wendland JR, Veenstra-VanderWeele J, Denys D, Blom R, Deforce D, Van Nieuwerburgh F, Westenberg HG, Walitza S, Egberts K, Renner T, Miguel EC, Cappi C, Hounie AG, Conceição do Rosário M, Sampaio AS, Vallada H, Nicolini H, Lanzagorta N, Camarena B, Delorme R, Leboyer M, Pato CN, Pato MT, Voyiaziakis E, Heutink P, Cath DC, Posthuma D, Smit JH, Samuels J, Bienvenu OJ, Cullen B, Fyer AJ, Grados MA, Greenberg BD, McCracken JT, Riddle MA, Wang Y, Coric V, Leckman JF, Bloch M, Pittenger C, Eapen V, Black DW, Ophoff RA, Strengman E, Cusi D, Turiel M, Frau F, Macciardi F, Gibbs JR, Cookson MR, Singleton A; North American Brain Expression Consortium, Hardy J; UK Brain Expression Database, Crenshaw AT, Parkin MA, Mirel DB, Conti DV, Purcell S, Nestadt G, Hanna GL, Jenike MA, Knowles JA, Cox N, and Pauls DL. (2013) Genome-wide association study of obsessive-compulsive disorder. Molecular Psychiatry 18(7):788-798. PMCID: PMC4218751 (PDF file)

*** Wang, L., Liu, X., Luo, X., Zeng, M., Zuo, L., and Wang, K.-S. (2013) Genetic Variants in the Fat Mass- and Obesity-Associated (FTO) Gene are Associated with Alcohol Dependence. Journal of Molecular Neuroscience 51(2):416-424. PMID: 23771786 (PDF file)

*** Wen, Y, Schaid, D.J., and Lu, Q. (2013) A bivariate Mann-Whitney approach for unraveling genetic variants and interactions contributing to comorbidity. Genetic Epidemiology 37(3):248-255. PMID: 23334941. (PDF file)

*** Zuo, L.J., Saba, L., Wang, K.S., Zhang, X.Y., Krystal, J.H., Tabakoff, B., and Luo, X.G. (2013) Exome-Wide Association Study of Replicable Nonsynonymous Variants Conferring Risk for Alcohol Dependence. Journal of Studies on Alcohol and Drugs 74(4):622-625. PMID: 23739027. (PDF file)

*** Zuo, L., Wang, K., Zhang, X.Y., Krystal, J.H., Li, C.S., Zhang, F., Zhang, H., and Luo, X. (2013) NKAIN1-SERINC2 is a functional, replicable and genome-wide significant risk gene region specific for alcohol dependence in subjects of European descent. Drug and Alcohol Dependence 129(3):254-264. PMID: 23455491 (PDF file)

*** Zuo, L., Wang, K.S., Zhang, X.Y., Li, C.S., Zhang, F., Wang, X., Chen, W., Gao, G., Zhang, H., Krystal, J.H., and Luo, X. (2013) Rare SERINC2 variants are specific for alcohol dependence in individuals of European descent. Pharmacogenetics and Genomics 23(8):395-402. PMID: 23778322 (PDF file)

*** Zuo, L., Wang, K., Zhang, X., Pan, X., Wang, G., Krystal, J.H., Zhang, H., and Luo, X. (2013) Sex chromosome-wide association analysis suggested male-specific risk genes for alcohol dependence. Psychiatric Genetics 23(6):233-238 PMID: 23907288 (PDF file)

*** Zuo, L., Wang, K., Zhang, X.Y., Pan, X., Wang, G., Tan, Y., Zhong, C., Krystal, J.H., State, M., Zhang, H., and Luo, X. (2013) Association between common alcohol dehydrogenase gene (ADH) variants and schizophrenia and autism. Human Genetics 132(7):735-743 PMID: 23468174 (PDF file)

*** Zuo, L., Zhang, H., Malison, R.T., Li, C.S., Zhang, X.Y., Wang, F., Lu, L., Lu, L., Wang, X., Krystal, J.H., Zhang, F., Deng, H.W., and Luo, X. (2013) Rare ADH variant constellations are specific for alcohol dependence. Alcohol and Alcoholism 48(1):9-14. PMID: 23019235 (PDF file)

*** Zuo, L., Zhang, X.Y., Wang, F., Li, C.S., Lu, L., Ye, L., Zhang, H., Krystal, J.H., Deng, H.W., and Luo X. (2013) Genome-wide significant association signals in IPO11-HTR1A region specific for alcohol and nicotine dependence. Alcoholism: Clinical and Experimental Research 37(5):730-739 PMID: 23216389 (PDF file)

2012

Fang, Y.H. and Chiu, Y.F. (2012).
SVM-based generalized multifactor dimensionality reduction approaches for detecting gene-gene interactions in family studies.
Genetic Epidemiology 36(2):88-98. PMID: 2285147.

*** Frank, J., Cichon, S., Treutlein, J., Ridinger, M., Mattheisen, M., Hoffmann, P., Herms, S., Wodarz, N., Soyka, M., Zill, P., Maier, W., Mössner, R., Gaebel, W., Dahmen, N., Scherbaum, N., Schmäl, C., Steffens, M., Lucae, S., Ising, M., Müller-Myhsok, B., Nöthen, M.M., Mann, K., Kiefer, F., and Rietschel M. (2012).
Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster.
Addiction Biology 17(1):171-180. PMCID: PMC3245349

*** Guo, X., Liu, Z., Wang, X., and Zhang, H. (2012).
Large scale association analysis for drug addiction: results from SNP to gene.
ScientificWorldJournal 2012:939584. PMCID: PMC3543790

*** Han, S., Yang, B.Z., Kranzler, H.R., Oslin, D., Anton, R., Farrer, L.A., and Gelernter, J. (2012).
Linkage analysis followed by association show NRG1 associated with cannabis dependence in African Americans.
Biological Psychiatry 72(8):637-644.

*** Jackson, K.J., Sanjakdar, S.S., Chen, X., and Damaj, M.I. (2012).
Nicotine reward and affective nicotine withdrawal signs are attenuated in calcium/calmodulin-dependent protein kinase IV knockout mice.
PLoS One 7(11):e51154. PMID: 23226481. (PDF file)

*** Karpyak, V.M., Geske, J.R., Colby, C.L., Mrazek, D.A., and Biernacka, J.M. (2012)
Genetic variability in the NMDA-dependent AMPA trafficking cascade is associated with alcohol dependence.
Addiction Biology 17(4):798-806. PMCID: PMC3197973 (PDF file)

Listgarten, J., Lippert, C., Kadie, C.M., Davidson, R.I., Eskin, E., and Heckerman, D. (2012).
Improved linear mixed models for genome-wide association studies.
Nature Methods 9: 525-526.

*** Shirley, M.D., Baugher, J.D., Stevens, E.L., Tang, Z., Gerry, N., Beiswanger, C.M., Berlin, D.S., and Pevsner, J. (2012).
Chromosomal variation in lymphoblastoid cell lines.
Human Mutation 33(7):1075-1086. PMCID: PMC3370055

Thornton, T., Zhang, Q., Cai, X., Ober, C., and McPeek, M.S. (2012).
XM: Association testing on the X chromosome in case-control samples with related individuals.
Genetic Epidemiology 36(5):438-450.

*** Wang, K.S., Liu, X., Aragam, N., Mullersman, J.E., Jian, X., Pan, Y., and Liu, Y. (2012).
Polymorphisms in ABLIM1 are associated with personality traits and alcohol dependence.
Journal of Molecular Neuroscience 46(2):265-271.

*** Wang, K.S., Liu, X., Zhang, Q., Wu, L.Y., and Zeng, M. (2012).
Genome-wide association study identifies 5q21 and 9p24.1 (KDM4C) loci associated with alcohol withdrawal symptoms.
Journal of Neural Transmission 119(4):425-433.

*** Wang, K.S., Liu, X., Zhang, Q., and Zeng, M. (2012).
ANAPC1 and SLCO3A1 are associated with nicotine dependence: Meta-analysis of genome-wide association studies.
Drug Alcohol Depend124(3):325-332.

*** Wang, K.S., Liu, X., Zheng, S., Zeng, M., Pan, Y., and Callahan, K. (2012).
A novel locus for body mass index on 5p15.2: A meta-analysis of two genome-wide association studies.
Gene 500(1):80-84.

Zhu, W., Jiang, Y., and Zhang, H. (2012).
Nonparametric covariate-adjusted association tests based on the generalized Kendall’s Tau.
Journal of the American Statistical Association 107(497):1-11.

*** Zuo, L., Gelernter, J., Zhang, C.K., Zhao, H., Lu, L., Kranzler, H.R., Malison, R.T., Li, C.S., Wang, F., Zhang, X.Y., Deng, H.W., Krystal, J.H., Zhang, F., sand Luo, X. (2012).
Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q.
Neuropsychopharmacology 37(2):557-566. PMCID: PMC3242317

*** Zuo, L., Zhang, F., Zhang, H., Zhang, X.Y., Wang, F., Li, C.S., Lu, L., Hong, J., Lu, L., Krystal, J.H., Deng, H.W., and Luo X. (2012).
Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence.

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 159B(4):437-444. PMCID: PMC3405545

2011

*** Chen, X., Cho, K., Singer, B.H., and Zhang, H. (2011).
The nuclear transcription factor PKNOX2 is a candidate gene for substance dependence in European-origin women.
PLoS One 6(1):e16002.

*** Drgon, T., Johnson, C.A., Nino, M., Drgonova, J., Walther, D.M., and Uhl, G.R. (2011).
“Replicated” genome wide association for dependence on illegal substances: genomic regions identified by overlapping clusters of nominally positive SNPs.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 156:125-138.

Feng, Z., Wong, W., Gao, X., and Schenkel, F. (2011).
Generalized genetic association study with samples of related individuals.
Annals of Applied Statistics 5(3):2019-2030.

Jian, X.Q., Wang, K.S., Wu, T.J., Hillhouse, J.J., and Mullersman, J.E. (2011).
Association of ADAM10 and CAMK2A polymorphisms with conduct disorder: Evidence from family-based studies.
Journal of Abnormal Child Psychology 39(6):773-82.

*** Johnson, C., Drgon, T., Walther, D., and Uhl, G.R. (2011).
Genomic regions identified by overlapping clusters of nominally-positive SNPs from genome-wide studies of alcohol and illegal substance dependence.
PLoS One 6(7):e19210. PMCID: PMC3144872. (PDF file)

Lippert, C., Listgarten, J., Liu, Y., Kadie, C.M., Davidson, R.I., and Heckerman, D. (2011).
FaST linear mixed models for genome-wide association studies.
Nature Methods 8(10):833-835.

Pan, Y., Wang, K.S., and Aragam, N. (2011).
NTM and NR3C2 polymorphisms influencing intelligence: family-based association studies.
Progress in Neuro-Psychopharmacology & Biological Psychiatry 35(1):154-160.

Wang, K.S., Liu, X., Aragam, N., Jian, X., Mullersman, J.E., Liu, Y., and Pan, Y. (2011).
Family-based association analysis of alcohol dependence in the COGA sample and replication in the Australian twin-family study.
Journal of Neural Transmission 118(9): 1293-1299.

Wang, K.S., Liu, X., Zhang, Q., Pan, Y., Aragam, N., and Zeng, M. (2011).
A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.
Journal of Psychiatric Research 45(11):1419-1425.

Wang, Z. (2011).
Direct assessment of multiple testing correction in case-control association studies with related individuals.
Genetic Epidemiology 35(1):70-79.

Zuo, L., Zhang, C.K., Wang, F., Li, C.S., Zhao, H., Lu, L., Zhang, X.Y., Lu, L., Zhang, H., Zhang, F., Krystal, J.H., and Luo, X. (2011).
A novel, functional and replicable risk gene region for alcohol dependence identified by genome-wide association study.
PLoS One 6(11):e26726. PMCID: PMC3210123

2010

Chiu, Y.-F., Chiou, J.-M., Liang, K.-Y., and Lee, C.-Y. (2010).
Incorporation of covariates in simultaneous localization of two linked loci using affected relative pairs.
BMC Genetics 11:67. (PDF file)

Diao, G., and Lin, D.Y. (2010).
Variance-components methods for linkage and association analysis of ordinal traits in general pedigrees.
Genetic Epidemiology 34(3):232-7. PMID: 19918762 (PDF file)

*** Drgon, T., Zhang, P.-W., Johnson, C., Walther, D., Hess, J., Nino, M., and Uhl, G.R. (2010).
Genome wide association for addiction: replicated results and comparisons of two analytic approaches.
PLoS One 5(1):e8832. PMCID: PMC2809089. (PDF file)

Han, S., Gelernter, J., Luo, X., and Yang, B.Z. (2010).
Meta-analysis of 15 genome-wide linkage scans of smoking behavior.
Biological Psychiatry 67(1):12-19. PMID: 19819424 (PDF file)

*** Noor, A., Whibley, A., Marshall, C.R., Gianakopoulos, P.J., Piton, A., Carson, A.R., Orlic-Milacic, M., Lionel, A.C., Sato, D., Pinto, D., Drmic, I., Noakes, C., Senman, L., Zhang, X., Mo, R., Gauthier, J., Crosbie, J., Pagnamenta, A.T., Munson, J., Estes, A.M., Fiebig, A., Franke, A., Schreiber, S., Stewart, A.F., Roberts, R., McPherson, R., Guter, S.J., Cook, E.H., Jr., Dawson, G., Schellenberg, G.D., Battaglia, A., Maestrini, E.; Autism Genome Project Consortium, Jeng, L., Hutchison, T., Rajcan-Separovic, E., Chudley, A.E., Lewis, S.M., Liu, X., Holden, J.J., Fernandez, B., Zwaigenbaum, L., Bryson, S.E., Roberts, W., Szatmari, P., Gallagher, L., Stratton, M.R., Gecz, J., Brady, A.F., Schwartz, C.E., Schachar, R.J., Monaco, A.P., Rouleau, G.A., Hui, C.C., Lucy Raymond, F., Scherer, S.W., and Vincent, J.B. (2010).
Disruption at the PTCHD1 locus on Xp22.11 in autism spectrum disorder and intellectual disability.
Science Translational Medicine 2(49):49ra68. PMCID: PMC2987731. (PDF file)

***Thornton, T. and McPeek, M.S. (2010).
ROADTRIPS: Case-control association testing with partially or completely unknown population and pedigree structure.
American Journal of Human Genetics 86(2):172-84. PMCID: PMC2820184. (PDF file)

Zhang, H., Liu, C.-T., and Wang, X. (2010).
An association test for multiple traits based on the generalized Kendall’s Tau.
Journal of the American Statistical Association 105(490):473-481.PMID: 20711441 (PDF file)

2009

Wang, Z. and McPeek, M.S. (2009).
An incomplete-data quasi-likelihood approach to haplotype-based genetic association studies on related individuals.
Journal of the American Statistical Association 104(487):1251-1260. PMID: 20428335 (PDF file)

2008

Feng, R. and Zhang, H. (2008).
A score test for linkage analysis of ordinal traits based on IBD sharing.
Biostatistics 9(1):114-127.

Feng, R. and Zhang, H. (2008).
A genomic imprinting test for ordinal traits in pedigree data.
Genetic Epidemiology 32(2):132-142.

Ishiguro, H., Gong, J.P., Hall, F.S., Arinami, T., and Uhl, G.R. (2008).
Association of PTPRB gene polymorphism with drug addiction.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 147B(7):1167-1172.

Jacobson, K.C., Beseler, C.L., Lasky-Su, J., Faraone, S.V., Glatt, S.J., Kremen, W.S., Lyons, M.J., and Tsuang, M.T. (2008).
Ordered subsets linkage analysis of antisocial behavior in substance use disorder among participants in the Collaborative Study on the Genetics of Alcoholism.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 147B(7):1258-1269.

Jonasdottir, G., Becker, T., Humphreys, K., and Palmgren, J. (2008).
Testing association in the presence of linkage using the GRE and multiple markers.
Genetic Epidemiology 32(5):425-433.

Kim, Y., Duggal, P., Gillanders, E.M., Kim, H., andBailey-Wilson, J.E. (2008).
Examining the effect of linkage disequilibrium between markers on the Type I error rate and power of nonparametric multipoint linkage analysis of two-generation and multigenerational pedigrees in the presence of missing genotype data.
Genetic Epidemiology 32(1):41-51. PMCID: PMC2216429

Yang, H.C., Hsieh, H.Y., and Fann, C.S. (2008).
Kernel-based association test.
Genetics 179(2):1057-1068. PMCID: PMC2429859 (PDF file)

2007

Dietter,. J., Mattheisen, M., Fürst, R., Rüschendorf, F., Wienker, T.F., and Strauch, K. (2007).
Linkage analysis using sex-specific recombination fractions with GENEHUNTER-MODSCORE
Bioinformatics 23(1):64-70.

Ducci, F., Enoch, M.A., Funt, S., Virkkunen, M., Albaugh, B., and Goldman, D. (2007).
Increased anxiety and other similarities in temperament of alcoholics with and without antisocial personality disorder across three diverse populations.
Alcohol 41(1):3-12.

Ishiguro, H., Walther, D., Arinami, T., and Uhl, G.R. (2007).
Variation in a bicarbonate co-transporter gene family member SLC4A7 is associated with propensity to addictions: a study using fine-mapping and three samples.
Addiction 102(8):1320-1325.

Thornton, T. and McPeek, M.S. (2007).
Case-control association test with related individuals: A more powerful quasi-likelihood Score test.
American Journal of Human Genetics 81(2):321-337. PMCID: PMC1950805 (PDF file)

2006

Diao, G. and Lin, D.Y. (2006).
Improving the power of association tests for quantitative traits in family studies.
Genetic Epidemiology 30:301-313.

Diao,. G. and Lin, D.Y. (2006).
Semiparametic variance-component models for linkage and association analyses of censored trait data.
Genetic Epidemiology 30:570-581.

Wang, X., Ye, Y., and Zhang, H. (2006).
Family-based association tests for ordinal traits adjusting for covariates.
Genetic Epidemiology 30(8):728-736.

Zhang, H., Wang, X., and Ye, Y. (2006).
Detection of genes for ordinal traits in nuclear families and a unified approach for association studies.
Genetics 172(1):693-699. (PDF file)

1999

Sheffield, L.J., Knauert, M.P., Pakstis, A.J., Zhao, H., and Kidd, K.K. (1999)
Analyses of the COGA data set in one ethnic group with examinations of alternative definitions of alcoholism
Genetic Epidemiology 17(Suppl 1):S319-324. PMID: 10597456



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