Research10/21/2025 02:00:00 AMThis year marks the 25th anniversary of a discovery that changed the course of medicine and represents an enduring chapter in Downstate’s history, when Downstate’s Robert F. Furchgott, Ph.D., UCLA’s Louis J. Ignarro, Ph.D., and University of Texas’s Ferid Murad, Ph.D., received the Nobel Prize in Physiology or Medicine for demonstrating that nitric oxide (NO) is a signaling molecule in the cardiovascular system. Their work revealed that NO regulates blood pressure, circulation, immune defense, and nervous system signaling, thereby fundamentally redefining our understanding of cardiovascular health.Office of the President/var/staging/oucampus/suny-downstate/downstate/about/office-of-the-president/presidents-bulletin/2025/10-21/07-molecule-discovery-that-changed-medicine.xmlResearchRobert F. FurchgottResearch