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Faculty Research in the Department of Pathology

Core Facilities

 

Virginia M Anderson, MD, Morphologic alterations in pediatric and perinatal disease including the placenta
in HIV disease, congenital malformations especially congenital heart disease.

Juan Marcos Alarcon, PhD, Molecular and cellular mechanisms underlying the interaction between distinct forms of synaptic plasticity in the CA1 area of the rodent hippocampus: consequences at synaptic, dendritic and neuron-wide level and impact on the hippocampal network.

Constantine Axiotis, MD The expression of the multidrug resistance gene (MDR-P-glycoprotein) in human
tumors; and the molecular pathology of breast cancer.

Randall L. Barbour, PhD, Optical tomographic imaging methods for the evaluation of tissue function.

Helen G. Durkin, PhD, Immune responses in HIV-1 disease. Regulation of allergic/IgE responses in humans and rodents. Neural regulation of immune responses.

Susan RS Gottesman, MD/PhD, Studying the changes in the immune system during normal aging in mice. Study
the characteristics of lymphoid malignancies using patient material

Alejandro Iván Hernández, PhD, Understanding the molecular mechanisms regulating long-term synaptic plasticity and the alterations of those mechanisms associated with neurodegenerative disorders and drug addiction.

Joan Howanitz, MD, Clinical chemistry including hemoglobinopathies; critical results for sodium and
cardiac marker utilization.

Peter Howanitz, MD, Quality of care; chemical pathology.

Jenny Libien, MD/PhD, Function of retinoids (vitamin A and its analogues) and retinoid transport proteins (RBP, TTR) in the central nervous system. The birth and survival of new neurons in the adult dentate gyrus in neurodegenerative diseases.

Josef Michl, MD, Study of cells in host defense against infections and tumors. Carcinogenesis in the exocrine pancreas in in vitro and in vivo models to identify disease-specific molecules and develop early diagnostic and effective therapeutic tools using cellular, molecular, biochemical and immunological approaches.

Suzanne S. Mirra, MD, Neuropathology of Alzheimer's disease and overlap with other neurodegenerative disorders and cerebrovascular disease.

Maja Nowakowski, PhD, Immune system-pathogen interactions. Effects of viral infection on macrophage physiology and immune functions. Systemic and local lung immunity in HIV-1 disease, tuberculosis and chronic inflammatory lung diseases. Regulation of nitric oxide generation by human macrophages and other cell types.

Matthew R. Pincus, MD/PhD, Oncogenesis, oncoprotein structure, mitogenic signal transduction, design of anti-cancer agents.

Martin J Salwen, MD, Define outer limits of laboratory test analyses. Develop programs for interpretive analysis of clinical laboratory data using rule-based logic and pattern analysis. Programs have incorporated modules for instruction in testing strategies for differential evaluation of patients. Programs have been developed for Erythocytosis. Strategies for rapid bacterial identification in sepsis.

Charles Shao, MD, The pathogenesis of neurodegenerative diseases, especially Alzheimer’s Disease (AD) the most common form of memory disorders.