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Department of Otolaryngology - Research Report

Ongoing Research Projects

Research Report

In the year 2015-2016, Drs. Kollmar, Sundaram, Silverman, Stewart, and Alessi continued their work supported by an R21 from the NIDCD studying the restoration of recurrent laryngeal nerve function after injury in a rat model. Dr. Alessi presented their work on the effect of anesthesia on vocal fold motion and breathing patterns at the 2015 Annual Meeting of the American Academy of Otolaryngology – Head and Neck Surgery.  The team has also collaborated with Dr. Stewart, Dr. Arjomandi and Dr. Kaplowitz to study post-obstructive pulmonary edema as a cause of sudden death in seizures, also in the rat model.  Dr. Arjomandi presented this work at the 2016 meeting of the Association for Research in Otolaryngology.  Dr. Chernichenko received a New York State ECRIP Fellowship Award to study the role of Rho GTPases in perineural invasion in a zebrafish model and Dr. Kollmar is continuing his work studying the molecular genetics of otolith formation in the zebrafish.  Drs. Butts and Gitman were awarded the SUNY Downstate President's Health Disparities Grant studying epidemiological factors associated with orofacial clefting in New York City.  The 2015 recipients of the SUNY Downstate Department of Otolaryngology Dr. Frank E. Lucente Resident Research Grants, made possible by the generous donation of a former graduate of our program Dr. Dennis Lee, were Dr. Kaplowitz for his work on a novel tracheostomy tube in mice to study sudden death in seizures and Dr. Ho to study nationwide characteristics and outcomes of patients undergoing laryngeal cleft repair.

Dr. Rosenfeld served as Senior Advisor for Guidelines and Quality for AAO-HNS, and helped develop clinical practice guidelines on rhinoplasty, otitis media with effusion and neck masses in adults and a clinical consensus statement development manual.  Drs. Goldstein, Rosenfeld and Silverman are the lead investigators for a multi-institutional study validating the Clinical Assessment Score-15 (CAS-15) for pediatric sleep-disordered breathing.   Drs. Butts and Gitman presented their work on the epidemiologic factors associated with the prevalence of orofacial clefts in New York City at the 73rd meeting of the American Cleft Palate- Craniofacial Association.  Dr. Goldstein was awarded the Third Place Poster Award for her work on developmental delay in young children with sleep-disordered breathing at the annual meeting of the American Society of Pediatric Otolaryngology.  Drs. Kaplowitz and Floyd presented their research at the 11th Metropolitan NY Resident Research Day Symposium.

Drs. Sundaram and Goldstein were guest editors of a special issue of the International Journal of Head and Neck Surgery honoring Dr. Lucente.  Drs. Har-El, Sperling, Boruk, Bentsianov, Mor, Alessi, Kohli, Ferzli, Ho and Kaplowitz all contributed articles to this issue.  Notable publications include Dr. Abramowitz’, Dr. Thakkar’s and Dr. Rosenfeld’s Adverse Event Reporting for Proton Pump Inhibitor Therapy: An Overview of Systematic Reviews published in Otolaryngology Head and Neck Surgery, Dr. Goldstein's Developmental Delay in Young Children with Sleep-Disordered Breathing Before and After Tonsil and Adenoid Surgery published in the International Journal of Pediatric Otorhinolaryngology, Dr. Rosenfeld’s Clinical Consensus Statement Development Manual published in Otolaryngology Head and Neck Surgery, and Dr. Lewis’, Dr. Earley’s , Dr. Rosenfeld’s, and Dr. Silverman’s  Surgical Treatment for Adult Laryngotracheal Stenosis, a Systematic Review published in The Laryngoscope.

Research Projects

Richard M. Rosenfeld, MD, MPH

  1. AAO-HNS clinical practice guideline on adult sinusitis
  2. AAO-HNS clinical practice guideline on otitis media with effusion
  3. AAO-HNS clinical consensus statement on nasal septoplasty
  4. AAO-HNS clinical consensus statement development manual
  5. Multiple ongoing projects assisting otolaryngology residents with research design, systematic review, and data analysis

Boris Bentsianov, MD

  1. Voice outcomes for in office versus injection laryngoplasty, a systematic review.
  2. Dermatologic Manifestation of Streptococcal Infection: Tonsillectomy as a Treatment for Guttate Psoriasis

Sydney Butts, MD

  1. Perceptual Assessment of Velopharyngeal Dysfunction by Otolaryngology Residents.
  2. Epidemiological Factors Associated with Orofacial Clefting in New York City.

Natalya Chernichenkor, MD

  1. A novel xenograft zebrafish model to study the role of the Rho GTPases in perineural invasion

Nira Goldstein, MD

  1. Developmental delay in young children with sleep-disordered breathing before and after tonsil and adenoid surgery
  2. Prospective evaluation of angioedema: An extubation protocol.
  3. The impact of adenotonsillectomy on pediatric asthma
  4. Multi-Institutional Validation of the Clinical Assessment Score-15 (CAS-15) for Pediatric Sleep-Disordered Breathing
  5. Analysis of outcomes and complications from button batteries as foreign bodies in the ear, nose or throat
  6. Third branchial cleft cyst with mycobacterium infection
  7. The role of corticosteroids in pediatric acute sinusitis with orbital complications

Richard Kollmar, PhD

  1. Restoration of Recurrent-Laryngeal-Nerve Function after Injury in a Rat Model
  2. Laryngospasm during Seizures 
  3. A Novel Zebrafish Xenograft Model to Study the Role of Rho GTPases in Perineural Invasion 
  4. Molecular Genetics of Otolith Formation in the Zebrafish

Eli Gordin, MD

  1. Systematic review of the efficacy of functional rhinoplasty as measured by the NOSE score.


Abraham Shulman, MD

  1. Calpain Inhibitor drug development- multicenter study SUNYDMC/U Miami Department of Otolaryngology, Department of Otolaryngology, Wayne State  University
  2. Tympanic membrane displacement test- external determination intracranial pressure, Department of Otolaryngology, University of Miami
  3. TBI Investigation calpain Inhibitor ALA-1.0 animal model, SUNY TBI Group Noise induced tinnitus animal model - calpain Inhibitor ALA-1.0, Department of Otolaryngology, Wayne State

     4. Brain function and Tinnitus- Neurometrics, Department Psychiatry New York



Joshua Silverman, MD, PhD

  1. Systematic Review for Surgical Treatment of Adult and Adolescent Laryngotracheal Stenosis
  2. Systematic review for surgical treatment of pediatric laryngotracheal stenosis
  3. Asthma Outcomes after Adenotonsillectomy: A Systematic Review
  4. Restoration of Recurrent-Laryngeal-Nerve Function after Injury in a Rat Model
  5. Laryngospasm and apnea during seizures in a rat model
  6. Management of ACEI Angioedema: a tertiary care center's prospective experience
  7. Cervical Mature Teratoma Masquerading as a Thyroglossal Duct Cyst in an Adult with Thyroid Cancer
  8. Treatment of Laryngotracheal Stenosis: The Brooklyn Experience
  9. Multi-Institutional Validation of the Clinical Assessment Score-15 (CAS-15) for Pediatric Sleep-Disordered Breathing

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