Current Topics in Ophthalmology
—Investigations of chronobiology and ocular disease, in collaboration with the University of California at San Diego. This work, supported by the National Institutes of Health, involves extensive investigations in the area of sleep, with emphasis on diurnal changes in ocular blood flow during sleep and the role of light deprivation and depression.
—Also in collaboration with Indiana University, investigations describing ocular blood flow in individuals with glaucoma, diabetes, age-related macular degeneration and other ocular diseases. These studies have detected blood flow abnormalities that have not been described previously.
—Investigations in collaboration with Columbia University are focusing on effective interventions to increase treatment compliance among individuals who screen positive for glaucoma.
—Mutational analysis in patients with X-linked retinitis pigmentosa and Lebers congenital amauosis are being performed in collaboration with Dr. Anand Swaroop of the University of Michigan. This ongoing study is an effort to understand the molecular genetics of retinal degenerations.
