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First-Year Medicine

Block 7: Gastrointestinal System & Intermediary Metabolism

The course currently has two major objectives:

  1. To learn the histology, biochemistry, and physiology of the gastrointestinal system and to be able to explain the pathways involved in intermediary metabolism.

    These studies will allow the students to integrate carbohydrate, lipid and protein metabolism. This knowledge of metabolism will lead them to appreciate the important roles of insulin, glucagon and allosteric regulators in normal physiological fed and fasted states. The students will then be prepared to apply their knowledge to disease states, such as diabetes.

    The major pathways involved in bioenergetics, and in carbohydrate, lipid, amino acid, and nucleotide metabolism are taught, with an emphasis on the nutritionally important aspects of these pathways.

    Many topics of clinical relevance are discussed relating to the gastrointestinal absorption of ions, water and nutrients.

    Two CBL cases have been designed to reinforce this material.

  2. To learn the anatomy and histology of the gastrointestinal tract and relate the structure of the function of the respective organs. The anatomy of the pelvis and perineum are covered in the same course because the close proximity of the structures encountered during dissection makes it a better educational experience to study them simultaneously.

This part of the curriculum is primarily conducted in the laboratory, but there are a number of lectures that complement the laboratories. There are also weekly laboratory review summary lectures.

The developmental anatomy of the urogenital tract complements the anatomy portion of the course.