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Department of Neurology

Faculty Research Interests

Charles K. Abrams, M.D., Ph.D. (x1270)

Mechanisms of human central and periphral nervous system diseases associated with mutations in connexins (gap junction proteins); the roles of gap junctions in peripheral nerve regeneration and inherited peripheral neuropathy.

Brian J. Anziska, M.D. (x2502)

Comparison of neurology undergraduate education in different medical schools using parameters such as over-night calls, and examination modalities.

Yaacov Anziska, M.D. (x2734)

HIV and toxic neuropathies, peripheral nerve injuries.

Satyakam Bhagavati, M.D. (x2041)

Skeletal muscle generation from embryonic stem cells:
Isolation of skeletal muscle stem cells from murine embryonic stem cells, studying their in vitro differentiation and proliferation characteristics and their ability to generate physiologically normal skeletal muscle after transplantation into dystrophic mice.

Ivan Bodis-Wollner, M.D., D.Sc. (x2975)

Vision and visual cognition suffer in dopaminergic deficiency states, such as in Parkinson's Disease. Our research studies evaluate electrophysiological neural network properties of dopaminergic circuits mediating vision , saccadic eye movements and visual cognition. In addition we study retinal impairment in PD, using optical coherence tomography, an in vivo imaging technique of the retina.

Geetha Chari, M.D. (x2959)

Epilepsy clinical studies.

Roger Q. Cracco, MD (x1355)

Magnetic stimulation of nervous system.

Joan Cracco, M.D. (x2035)

Mechanisms of long term potentiation.

Howard Crystal, M.D. (x2748)

Cognitive changes in HIV, genetics of substance abuse in HIV; computational models of working and procedural memory.

Radha Giridharan, M.D. (x2042)

Stroke in sickle cell disease. Clinical research in pediatric neurology topics.

Arthur C. Grant, M.D., Ph.D. (x2959)

Effect of epilepsy on perception; Quantitative EEG; Plasticity and learning

Patricia Kavanagh, M.D. (718-403-9855)

Clinical movement disorders studies, including Parkinson's disease, dystonia, essential tremor, and atypical parkinsonism.

Steven R. Levine, M.D., FAHA, FAAN (x3188)

 

Paul J. Maccabee, M.D. (x2430)

Physical modelling, in-vitro studies of nerve excitation using neuromagnetic stimulation. Developing clinical methods to detect abnormalities in the cauda equina and also the entire neuroaxis.

Lisa Merlin, M.D. (x3957)

Hippocampal electrophysiology: examination of the role of metabotropic glutamate receptors in seizure production and epileptogenesis, with the aim to develop ways to prevent epilepsy in at-risk patients and suppress seizures in refractory patients.

Herman Moreno, M.D. (x4660)

1) Use of fMRI in mouse models of neurodegenerative disease such as Alzheimer's and Down syndrome to study brain metabolism, as an early marker of the disease.

2) Basic electrophysiology and single cell calcium signaling to study brain circuits abnormalities in neurodegenerative disease in multiple mouse models.

Arthur L. Rose, M.D. (x3209)

FRAGILE X SYNDROME -
a. Mode of action of FMRP in the central nervous system
b. The mechanism of "toxic" FMR1 mRNA activity in carriers.

Daniel M. Rosenbaum, M.D. (x5745)

The focus of the lab is to study the underlying mechanisms of ischemic cell death. By obtaining a better understanding of the events that occur at a molecular level, therapies aimed at reducing neuronal damage may be developed. Specifically, we are focusing on the role of apoptosis in neuronal ischemia. The laboratory utilizes both cerebral and retinal models.

Another area of focus is neural stem and progenitor cells. The adult mammalian brain contains neural stem and progenitor cells that can proliferate, self-renew, and generate all of the cellular elements of the brain including neurons. During the past few years techniques have been developed which make it possible to isolate and expand, from developing or even adult CNS tissue, cells with properties characteristic of early neural multipotent progenitor or stem cells. These techniques have opened interesting new possibilities for the use of cells for CNS transplantation, neural replacement, and brain repair. This project will bring the rapidly expanding area of progenitor cells to bear on the problems of stroke and cerebral ischemia.

tel: 718-221-5745

Todd Sacktor, M.D. (x3933)

Protein kinase C, PKMzeta, long-term potentiation, memory storage.

Helen Valsamis, M.D. (x2768)

Investigations on the prevention of post-traumatic epilepsy


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