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Pediatric HIV/AIDS Cohort Study (PHACS)

The Pediatric HIV/AIDS Cohort Study (PHACS) network was established by NICHD in 2005 to address two critical pediatric HIV research questions: the long-term safety of fetal and infant exposure to prophylactic antiretroviral (ART) chemotherapy, and the effects of perinatally acquired HIV infection in adolescents. The goals of this network are to:

  • Create a body of data to understand more fully the effect of HIV on sexual maturation, pubertal development, and socialization of perinatally HIV-infected pre-adolescents and adolescents;
  • Acquire more definitive information regarding long-term safety of antiretroviral agents when used during pregnancy and in newborns;
  • Ensure a mechanism is in place to estimate the upper bounds of risk for children associated with the use of antiretrovirals in their HIV-infected pregnant mothers as recommended in the Public Health Service Guidelines to prevent perinatal HIV transmission; and
  • Ensure that the follow-up of these populations continues.

SUNY Downstate is one of 24 clinical sites across 13 states and Puerto Rico that were chosen to take part. Dr. Sheldon Landesman is the Principal Investigator. Enrollment of pregnant HIV+ women is currently open.

PHACS is located on the 4th floor of the Basic Sciences Building, Room 4-114.

For further information please contact:

Ava Dennie, PA
Study Coordinator
Phone: (718) 270-2966   
Fax: (718) 270-4137
email: ava.dennie@downstate.edu