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Howard Crystal, MD

Howard Crystal, MD
Professor of Neurology and Pathology


Dr. Crystal obtained his MD from the University of Pennsylvania Medical School in 1976.

Research Participation:
Howard Crystal is a professor of Neurology and Pathology and came to Downstate from the Albert Einstein College of Medicine in 2000. Most of his research at Einstein was on clinicopathological studies of cognitive changes in normal aging and dementia.

Current Research:
For the past year, he has been collaborating with other WIHS investigators in preparing studies of cognitive and behavioral changes in HIV. His RO-1, "Substance Abuse in HIV: Genetics and Disease Progression" in response to a recent RFA on psychiatric co-morbidity in HIV, will be funded. The genetic component is being done in collaboration with the Kreek Laboratory at Rockefeller University. He is also collaborating with Cliff Smith at Rush (as well as Jennifer Manly at Columbia University and Eileen Martin at the University of Iowa) on Neuropsychological and Structural Imaging studies of the effects of aging on cognition in women with HIV.

Current Research Support:
National Institute of Allergy and Infectious Diseases (NIAID) through a subcontract with Georgetown University

Substudy to the WIHS: Cognitive Function and Brain Structure in Women with HIV: Effects of age, illicit drug use, and Hepatitis C. The major aim of this pilot study is to explore the relationship between neurologic function, drug use and viral infections.
Role: Principal Investigator

National Institute on Mental Health (NIMH) and the National Institute on Drug Abuse (NIDA)

Substance Abuse in HIV: Genetics and Course (R01 MH076537-01). This is a collaboration with WIHS investigators and Dr. Mary Jeanne Kreek and her colleagues in the Laboratory of The Biology of Substance Abuse at Rockefeller University.
Role: Principal Investigator


SUNY Downstate Medical Center
450 Clarkson Avenue
MSC 25
Brooklyn, NY 11203
Phone: 718-270-6388
Fax: 718-270-8173