Cells of the anterior pituitary display the typical features of protein secreting cells (abundant RER, Golgi and secretory vesicles). Two types of cells can be distinguished: cells with small granules are basophils; cells with large granules are acidophils. Note that the granules in the pituitary cells, unlike the cells of the exocrine pancreas, are not polarized to one area of the cell. The granules of endocrine cells are released on all sides of the cells.