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Henri Begleiter Neurodynamics Laboratory

Reviewed Articles of HBNL

2012 - 2011 - 2010 -

2009 - 2008 - 2007 - 2006 - 2005 - 2004 - 2003 - 2002 - 2001 - 2000 -

1999 - 1998 - 1997 - 1996 - 1995 - 1994 - 1993 - 1992 - 1991 - 1990 -

1989 - 1988 - 1987 - 1986 - 1985 - 1984 - 1983 - 1982 - 1981 - 1980 -

1979 - 1978-1976

Henri Begleiter's Publications before 1976

A complete list of all publications of the Henri Begleiter Neurodynamics Laboratory as a pdf file.

Publications in 2012

Kamarajan, C., Rangaswamy, M., Manz, N., Chorlian, D.B., Pandey, A.K., Roopesh, B.N., and Porjesz, B. (2012).
Topography, Power and Current Source Density of Theta Oscillations during Reward Processing as Markers for Alcohol Dependence.
Human Brain Mapping xx:xxx-xxx. (pdf file)

Pandey, A.K., Kamarajan, C., Tang, Y., Chorlian, D.B., Roopesh, B.N., Manz, N., Stimus, A. Rangaswamy, M., and Porjesz, B. (2012).
Neurocognitive Deficits in Male Alcoholics: An ERP/sLORETA Analysis of the N2 Component in an Equal Probability Go/NoGo Task.
Biological Psychiatry xx:xxx-xxx.

Pandey, A.K., Kamarajan, C., Rangaswamy, M., and Porjesz, B. (2012).
Event-Related Oscillations in Alcoholism Research: A Review.
Journal of Addiction Research & Therapy xx:xxx-xxx.

Pandey, A.K., Kamarajan, C., Tang, Y., Chorlian, D.B., Roopesh, B.N.,  Manz, N., Stimus, A., Rangaswamy, M.,  and Porjesz, B. (2012)

Neurocognitive Deficits in Male Alcoholics: An ERP/sLORETA Analysis of the N2 Component in an Equal Probability Go/NoGo Task .

Biological Psychiatry 89:170-182, (pdf file)

In Collaboration:

Bierut, L.J., Goate, A.M., Breslau, N., Johnson, E.O., Bertelsen, S., Fox, L., Agrawal, A., Bucholz, K.K., Grucza, R., Hesselbrock, V., Kramer, J., Kuperman, S., Nurnberger, J., Porjesz, B., Saccone, N.L., Schuckit, M., Tischfield, J., Wang, J.C., Foroud, T., Rice, J.P., and Edenberg, H.J. (2012)

ADH1B is associated with alcohol dependence and alcohol consumption in populations of European and African ancestry.

Molecular Psychiatry xx:xxx-xxx (accepted for publication)

Edwards, A.C., Aliev, F., Bierut, L.J., Bucholz, K.K., Edenberg, H., Hesselbrock, V., Kramer ,J., Kuperman, S., Nurnberger, J.I. Jr, Schuckit, M.A., Porjesz, B., and Dick, D.M. (2012)

Genome-wide association study on comorbid depressive syndrome and alcohol dependence.
Psychiatric Genetics 22:31-41. (pdf file)

Kapoor, M., Wang, J.C., Bertelsen, S., Bucholz, K., Budde, J.P., Hinrichs, A., Agrawal, A., Brooks, A., Chorlian, D.B., Dick, D., Hesselbrock, V., Foroud, T., Kramer, J., Kuperman, J., Manz, N., Nurnberger Jr, J., Porjesz, B., Rice, J.P., Tischfield, J., Xuei, X., Schuckit, M., Edenberg, H.J., Bierut, L.J., and Goate, A. (2012).
Variants located upstream of CHRNB4 on chromosome 15q25.1 are associated with age at onset of daily smoking and habitual smoking.
PLoS ONE xx:xxx-xxx (accepted for publication)

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Publications in 2011

In Collaboration:

Derringer, J., Krueger, R.F., Manz, N., Porjesz, B., Almasy, L., Bookman, E., Edenberg, H.J., Kramer, J.R., Tischfield, J.A., GENEVA consortium, and, Bierut, L.J. (2011).
Non-replication of an association of SGIP1 SNPs with alcohol dependence and theta EEG power.
Psychiatric Genetics 21:265-266. (pdf file and supplement)

Dick, D.M., Aliev, F., Krueger, R.F., Edwards, A., Agrawal, A., Lynskey, M., Lin, P., Schuckit, M., Hesselbrock, V., Nurnberger, J. Jr, Almasy, L., Porjesz, B., Edenberg, H.J., Bucholz, K., Kramer, J., Kuperman, S., and Bierut, L. (2011).
Genome-wide association study of conduct disorder symptomatology.
Molecular Psychiatry 16:800-808. (pdf file)

Lin, P., Hartz, S.M., Wang, J.C., Krueger, R.F., Foroud, T.M., Edenberg, H.J., Nurnberger, J.I. Jr, Brooks, A.I., Tischfield, J.A., Almasy, L., Webb, B.T., Hesselbrock, V.M., Porjesz, B., Goate, A.M., Bierut, L.J., and Rice, J.P. (2011).
Copy number variation accuracy in genome-wide association studies.
Human Heredity 71:141-147. (pdf file)

Zlojutro, M., Manz, N., Rangaswamy, M., Xuei, X.,  Flury-Wetherill, L., Koller, D., Bierut, L.J.,  Goate, A., Hesselbrock, V., Kuperman, S., Nurnberger Jr., J., Rice, J.P., Schuckit, M.A., Foroud, T., Edenberg, H.J., Porjesz, B., and Almasy, L. (2011).
Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 156:44-58. (pdf file)

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Publications in 2010

Chen, A.C., Manz, N., Tang, Y., Rangaswamy, M., Almasy, L., Kuperman, S., Nurnberger Jr., J. , O'Connor, S.J., Edenberg, H.J., Schuckit, M.A., Tischfield, J., Foroud, T., Bierut, L.J., Rohrbaugh, J., Rice, J.P., Goate, A., Hesselbrock, V., and Porjesz, B. (2010).
Single Nucleotide Polymorphisms in Corticotropin Releasing Hormone Receptor 1 Gene (CRHR1) Are Associated with Quantitative Traits of Event-Related Potential and Alcohol Dependence.
Alcoholism: Clinical and Experimental Research 34:988-996. (pdf file)

Kamarajan, C., Rangaswamy, M., Tang, Y., Chorlian, D.B., Pandey, A.K., Roopesh, B.N., Manz, N., Saunders, R., Stimus, A.T., and Porjesz, B. (2010).
Dysfunctional reward processing in male alcoholics: An ERP study during a gambling task.
Journal of Psychiatric Research 44:576-590. (pdf file)

Roopesh, B.N., Rangaswamy, M., Kamarajan, C., Chorlian, D.B., Pandey, A.K. and Porjesz, B. (2010).
Reduced Resource Optimization in Male Alcoholics: N400 in a Lexical Decision Paradigm .
Alcoholism: Clinical and Experimental Research 34:1904-1914. (pdf file)

In Collaboration:

Bauer, L., Dick, D., Bierut, L., Bucholz, K., Edenberg, H., Kuperman, S., Kramer, J., Nurnberger, J., O'Connor, S., Rice, J., Rohrbaugh, J., Schuckit, M., Tischfield, J., Porjesz, B. and Hesselbrock, V. (2010).
Obesity, smoking, and frontal brain dysfunction.
The American Journal on Addictions 19:391-400. (pdf file)

Bierut, L.J., Agrawal, A., Bucholz, K.K., Doheny, K.F., Laurie, C., Pugh, E., Fisher, S., Fox, L., Howells, W., Bertelsen, S., Hinrichs, A.L., Almasy, L., Breslau, N., Culverhouse, R.C., Dick, D.M., Edenberg, H.J., Foroud, T., Grucza, R.A., Hatsukami, D., Hesselbrock, V., Johnson, E.O., Kramer, J., Krueger, R.F., Kuperman, S., Lynskey, M., Mann, K., Neuman, R.J., Nöthen, M.M., Nurnberger, J.I. Jr, Porjesz, B., Ridinger, M., Saccone, N.L., Saccone, S.F., Schuckit, M.A., Tischfield, J.A., Wang, .J.C, Rietschel, M., Goate, A.M., Rice, J.P., as part of the Gene, Environment Association Studies (GENEVA) Consortium (2010).
A genome-wide association study of alcohol dependence.
Proceedings of the National Academy of Sciences of the United States of America 107:5082-5087. (pdf file and supplement)

Derringer, J., Krueger, R.F., Dick, D.M., Saccone, S., Grucza, R.A., Agrawal, A., Lin, P., Almasy, L., Edenberg, H.J., Foroud, T., Nurnberger, J.I. Jr, Hesselbrock, V.M., Kramer, J.R., Kuperman, S., Porjesz, B., Schuckit, M.A., Bierut, L.J.; Gene Environment Association Studies (GENEVA) Consortium (2010).
Predicting Sensation Seeking From Dopamine Genes: A Candidate-System Approach.
Psychological Science 21:1282-1290. (pdf file)

Dick, D.M., Aliev, F., Krueger, R.F., Edwards, A., Agrawal, A., Lynskey, M., Lin, P., Schuckit, M., Hesselbrock, V., Nurnberger, J. Jr, Almasy, L., Porjesz, B., Edenberg, H.J., Bucholz, K., Kramer, J., Kuperman, S., Bierut, L. (2010).
Genome-wide association study of conduct disorder symptomatology.
Molecular Psychiatry xxx:xxx-xxx. in press (pdf file)

Dick, D.M., Meyers, J., Aliev, F., Nurnberger, J. Jr, Kramer, J., Kuperman, S., Porjesz, B., Tischfield, J., Edenberg, H.J., Foroud, T., Schuckit, M., Goate, A., Hesselbrock, V., Bierut, L. (2010).
Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts.
Neuropsychiatric Genetics Part B: American Journal of Medical Genetics 153B:1179-1188. (pdf file)

Edenberg, H.J., Koller, D.L., Xuei, X., Wetherill, L., McClintick, J.N., Almasy, L., Bierut, L.J., Bucholz, K.K., Goate, A., Aliev, F., Dick, D., Hesselbrock, V., Hinrichs, A., Kramer, J., Kuperman, S., Nurnberger, J.I. Jr, Rice, J.P., Schuckit, M.A., Taylor, R., Todd Webb, B., Tischfield, J.A., Porjesz, B., and Foroud, T. (2010).
Genome-Wide Association Study of Alcohol Dependence Implicates a Region on Chromosome 11.
Alcoholism: Clinical and Experimental Research 34:840-852. (pdf file)

Kramer, J., Chan, G., Hesselbrock, V.M., Kuperman, S., Bucholz, K.K., Edenberg, H.J., Schuckit, M., Nurnberger Jr., J., Foroud, T., Dick, D.M., Bierut, L., and Porjesz, B. (2010).
A Principle Components Analysis of the abbreviated Desires for Alcohol Questionaire (DAQ).
Journal of Studies on Alcohol and Drugs 71:150-155. (pdf file)

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Publications in 2009

Chen, A., Tang, Y., Rangaswamy, M., Almasy, L., Kuperman, S., Nurnberger Jr.. J., O'Connor, S., Edenberg, H., Schuckit, M., Tischfield, J., Foroud, T., Bierut, L., Rohrbaugh, J., Bauer, L., Rice, J., Hesselbrock, V., Goate, A., and Porjesz, B. (2009).
Association of Single Nucleotide Polymorphisms in a Glutamate Receptor Gene (GRM8) with Theta Power of Event-Related Oscillations and Alcohol Dependence.
Neuropsychiatric Genetics Part B: American Journal of Medical Genetics 150B:359-368. (pdf file)

Chorlian, D.B., Rangaswamy, M., and Porjesz, B. (2009).
EEG Coherence: Topography and Frequency Structure.
Experimental Brain Research 198:59-83. (pdf file)

Kamarajan, C., Porjesz, B., Rangaswamy, M., Tang, Y., Chorlian, D.B., Padmanabhapillai, A., Saunders, R., Pandey, A.K., Roopesh, B.N., Manz, N., Stimus, A.T., and Begleiter, H. (2009).
Brain signatures of monetary loss and gain: Outcome-related potentials in a single outcome gambling task.
Behavioural Brain Research 197:62-76. (pdf file)

Roopesh, B.N., Rangaswamy, M., Kamarajan, C., Chorlian, D.B., Stimus, A.T., Bauer, L.O., Rohrbaugh, J. O'Connor, S.J., Kuperman, S., Schuckit, M., and Porjesz, B. (2009).
Priming Deficiency in Male Subjects at Risk for Alcoholism: The N4 During a Lexical Decision Task.
Alcoholism: Clinical and Experimental Research 33:2027-2036. (pdf file)

In Collaboration:

Wang, J.C., Grucza, R., Cruchaga, C., Hinrichs, A.L., Bertelsen, S., Budde, J.P., Fox, L., Goldstein, E., Reyes, O., Saccone, N., Saccone, S., Xuei, X., Bucholz, K., Kuperman, S., Nurnberger, J. Jr, Rice, J.P., Schuckit, M., Tischfield, J., Hesselbrock, V., Porjesz, B., Edenberg, H.J., Bierut, L.J., and Goate, A.M. (2009).
Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence.
Molecular Psychiatry 14:501-510. (pdf file)

Xuei X., Flury-Wetherill L., Dick D., Goate A., Tischfield J., Nurnberger J. Jr, Schuckit M., Kramer J., Kuperman S., Hesselbrock V., Porjesz B., Foroud T., and Edenberg H.J. (2009)
GABRR1 and GABRR2, encoding the GABA-A receptor subunits ▋ and ▌, are associated with alcohol dependence.
American Journal of Medical Genetics B: Neuropsychiatric Genetics 153B:418-427. (pdf file)

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Publications in 2008

Kamarajan, C., Rangaswamy, Chorlian, D. B., Manz, N., Tang, Y., Pandey, A. K., Roopesh, B. N., Stimus, A. T., and Porjesz, B. (2008).
Theta oscillations during the processing of monetary loss and gain: A perspective on gender and impulsivity.
Brain Research 1235:45:62. (pdf file)

Rangaswamy, M. and Porjesz, B. (2008).
Uncovering genes for cognitive (dys)function and predisposition for alcoholism spectrum disorders: A review of human brain oscillations as effective endophenotypes.
Brain Research 1235:153-171. (pdf file)

Rangaswamy, M. and Porjesz, B. (2008).
From Event-related Potential to Oscillations: Genetic Diathesis in Brain (Dys)Function and Alcohol Dependence.
Alcohol Research & Health 31:238-242. (pdf file)

In Collaboration:

Agrawal, A., Hinrichs, A.L., Dunn, G., Bertelsen, S., Dick, D.M., Saccone, S.F., Saccone, N.L., Grucza, R.A., Wang, J.C., Cloninger, C.R., Edenberg, H.J., Foroud, T., Hesselbrock, V., Kramer, J., Bucholz, K.K., Kuperman, S., Nurnberger, J.I. Jr, Porjesz, B., Schuckit, M.A., Goate, A.M., and Bierut., L.J. (2008).
Linkage scan for quantitative traits identifies new regions of interest for substance dependence in the Collaborative Study on the Genetics of Alcoholism (COGA) sample.
Drug and Alcohol Dependence 93:12-20. (pdf file)

Bierut, L.J., Stitzel, J.A., Wang, J.C., Hinrichs, A.L., Grucza, R.A., Xuei, X., Saccone, N.L., Saccone, S.F., Bertelsen, S., Fox, L., Horton, W.J., Breslau, N., Budde, J., Cloninger, C.R., Dick, D.M., Foroud, T., Hatsukami, D., Hesselbrock, V., Johnson, E.O., Kramer, J., Kuperman, S., Madden, P.A.F., Mayo, K., Nurnberger, J., Jr, Pomerleau, O., Porjesz, B., Reyes, O., Schuckit, M., Swan, G., Tischfield, J.A., Edenberg, H.J., Rice, J.P., and Goate, A.M. (2008).
Variants in Nicotinic Receptors and Risk for Nicotine Dependence.
American Journal of Psychiatry 165:1163-1171. (pdf file)

Dick, D.M., Aliev, F., Wang, J.C., Grucza, R.A., Schuckit, M., Kuperman, S., Kramer, J., Hinrichs, A., Bertelsen, S., Budde, J.P., Hesselbrock, V., Porjesz, B., Edenberg, H.J., Bierut, L.J., and Goate, A. (2008)
Using dimensional models of externalizing psychopathology to aid in gene identification.
Archives of General Psychiatry 65:310-318. (pdf file)

Dick, D.M., Aliev, F., Wang, J.C., Saccone, S., Hinrichs, A., Bertelsen, S., Budde, J., Saccone, N., Foroud, T., Nurnberger, J. Jr, Xuei, X., Conneally, P.M., Schuckit, M., Almasy, L., Crowe, R., Kuperman, S., Kramer, J., Tischfield, J.A., Hesselbrock, V., Edenberg, H.J., Porjesz, B., Rice, J.P., Bierut, L., and Goate, A. (2008).
A Systematic Single Nucleotide Polymorphism Screen to Fine-Map Alcohol Dependence Genes on Chromosome 7 Identifies Association With a Novel Susceptibility Gene ACN9.
Biological Psychiatry 63:1047-1053. (pdf file)

Edenberg, H.J., Xuei, X.L., Wetherill, L.F., Bierut, L., Bucholz, K., Dick, D.M., Hesselbrock, V., Kuperman, S., Porjesz, B., Schuckit, M.A., Tischfield, J.A., Almasy, L.A., Nurnberger, J.I., and Foroud, T. (2008).
Association of NFKB1, which encodes a subunit of the transcription factor NF-κB, with alcohol dependence.
Human Molecular Genetics 17:963-970. (pdf file)

Ghosh, S., Bierut, L.J., Porjesz, B., Edenberg, H.J., Dick, D., Goate, A., Hesselbrock, V., Nurnberger, J. Jr, Foroud, T., Kramer, J., Rice, J., and Begleiter, H.(2008).
A novel non-parametric regression reveals linkage on chromosome 4 for the number of externalizing symptoms in sib-pairs.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 147B:1301-1305. (pdf file)

Grucza, R.A., Wang, J.C., Stitzel, J.A., Hinrichs, A.L., Saccone, S.F., Saccone, N.L., Bucholz, K.K., Cloninger, C.R., Neuman, R.J., Budde, J.P., Fox, L., Bertelsen, S., Kramer, J., Hesselbrock, V., Tischfield, J., Nurnberger, J.I. Jr, Almasy, L., Porjesz, B., Kuperman, S., Schuckit, M.A., Edenberg, H.J., Rice, J.P., Goate, A.M., and Bierut, L.J. (2008).
A Risk Allele for Nicotine Dependence in CHRNA5 Is a Protective Allele for Cocaine Dependence.
Biological Psychiatry 64:922-929. (pdf file)

Kramer, J., Chan, G., Dick, D., Kuperman, S., Bucholz, K., Hesselbrock, V., Edenberg, H., Polgreen, L., Hesselbrock, V., Schuckit, M., Nurnberger Jr., J., Kapp, E., Porjesz, B., and Bierut, L. (2008)
Multiple-Domain Predictors of Problematic Alcohol Use in Young Adulthood.
Journal of Studies on Alcohol and Drugs 69:649-459. (pdf file)

Wetherill, L., Schuckit, M.A., Hesselbrock, V., Xuei, X., Liang, T., Dick, D.M., Kramer, J., Nurnberger Jr, J.I., Tischfield, J.A., Porjesz, B., Edenberg, H.J., and Foroud, T. (2008).
Neuropeptide Y Receptor Genes Are Associated With Alcohol Dependence, Alcohol Withdrawal Phenotypes, and Cocaine Dependence.
Alcoholism: Clinical and Experimental Rese arch 32:2031-2040. (pdf file)

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Publications in 2007

Chen, A.C.H., Porjesz, B., Rangaswamy, M., Kamarajan, C., Tang, Y., Jones, K.A., Chorlian, D.B., Stimus, A.T., and Begleiter H. (2007).
Reduced frontal lobe activity in subjects with high impulsivity and alcoholism.
Alcoholism: Clinical and Experimental Research 31:156-165. (pdf file)

Chorlian, D.B., Tang, Y., Rangaswamy, M., O'Connor, S.J., Rohrbaugh, J., Taylor, R., and Porjesz, B. (2007).
Heritability of EEG coherence in a large sib-pair population.
Biological Psychology 75:260-266. (pdf file)

Porjesz, B. and Li, T.K. (2007).
Impulsivity and addiction: a tribute to Henri Begleiter.
TheScientificWorldJOURNAL 7:131-141. (pdf file)

Porjesz, B. and Rangaswamy, M. (2007).
Neurophysiological endophenotypes, CNS disinhibition, and risk for alcohol dependence and related disorders.
TheScientificWorldJOURNAL 7:121-123. (pdf file)

Rangaswamy, M., Jones, K.A., Porjesz, B., Chorlian, D.B., Padmanabhapillai, A., Kamarajan, C. Kuperman, S., Rohrbaugh, J., O'Connor S., Bauer L.O., Schuckit, M., and Begleiter, H. (2007).
Delta and theta oscillations as risk markers in adolescent offspring of alcoholics.
International Journal of Psychophysiology 63:3-15. (pdf file).

Tang, Y., Chorlian, D.B., Rangaswamy, M., O'Connor S., Taylor, R., Rohrbaugh, J., Porjesz, B., and Begleiter, H. (2007).
Heritability of Bipolar EEG Spectra in a Large Sib-pair Population.
Behavior Genetics 37:302-313. (pdf file)

Tang, Y., Chorlian, D.B., Rangaswamy, M., Porjesz, B., Bauer, L., Kuperman, S., O'Connor, S., Schuckit, M., Stimus, A., and Begleiter, H. (2007).
Genetic influences on bipolar EEG power spectra.
International Journal of Psychophysiology 657:2-9. (pdf file)

In Collaboration:

Dick, D.M., Aliev, F., Kramer, J., Wang, J.C., Hinrichs, A., Bertelsen, S., Kuperman, S., Schuckit, M., Nurnberger, J., Edenberg, H.J., Porjesz, B., Begleiter, H., Hesselbrock, V., Goate, A., and Bierut, L. (2007).
Association of CHRM2 with IQ: Converging Evidence for a Gene Influencing Intelligence.
Behavior Genetics 37:265-272. (pdf file)

Dick, D.M., Wang, J.C., Plunkett, J., Aliev, F., Hinrichs, A., Bertelsen, S., Budde, J.P., Goldstein, E.L., Kaplan, D., Edenberg, H.J., Nurnberger, J. Jr, Hesselbrock, V., Schuckit, M., Kuperman, S., Tischfield, J., Porjesz, B., Begleiter, H., Bierut, L., and Goate, A. (2007).
Family-based association analyses of alcohol dependence phenotypes across DRD2 and neighboring gene ANKK1.
Alcoholism: Clinical and Experimental Research 31:1645-1653. (pdf file)

Foroud, T., Flury-Wetherill, L., Liang, T., Dick, D.M., Hesselbrock, V., Kramer, J., Nurnberger, Jr J.I., Schuckit, M., Carr, L., Porjesz, B., Xuei, X., and Edenberg, H.J. (2007).
Association of Alcohol Craving With α-Synuclein (SNCA).
Alcoholism: Clinical and Experimental Research 31:537-545. (pdf file)

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Publications in 2006

Begleiter, H. and Porjesz, B. (2006).
Genetics of human brain oscillations.
International Journal of Psychophysiology 60:162-171. (pdf file)

Chorlian, D.B., Porjesz, B., and Begleiter, H. (2006).
Amplitude modulation of gamma band oscillations at alpha frequency produced by photic driving.
International Journal of Psychophysiology 61:262-278. (pdf file)

Hayden, E.P., Wiegand, R.E., Meyer, E.T., Bauer, L.O., O'Connor, S.J., Nurnberger Jr., J.I., Chorlian, D.B., Porjesz, B., and Begleiter, H. (2006).
Patterns of Regional Brain Activity in Alcohol-Dependent Subjects.
Alcoholism: Clinical and Experimental Research 30:1986-1991. (pdf file)

Jones, K.A., Porjesz, B., Chorlian, D., Rangaswamy, M., Kamarajan, C., Padmanabhapillai, A., Stimus, A., and Begleiter, H. (2006)
S-transform time-frequency analysis of P300 reveals deficits in individuals diagnosed with alcoholism.
Clinical Neurophysiology 117:2128-2143. (pdf file)

Jones, K.A., Porjesz, B., Almasy, L., Bierut, L., Goate, A., Hinrichs, A., Rice, J.P., Rohrbaugh, J., Bauer, L.O., Crowe, R.R., Edenberg, H.J., Foroud, T., Hesselbrock, V., Kuperman, S., Nurnberger Jr, J., O'Connor, S.J., Schuckit, M.A., Tischfield, J.A., and Begleiter, H. (2006).
A Cholinergic Receptor Gene (CHRM2) Affects Event-related Oscillations.
Behavior Genetics 36:627-39. (pdf file)

Kamarajan, C., Porjesz, B., Jones, K., Chorlian, D., Padmanabhapillai, A., Rangaswamy, M., Stimus, A., and Begleiter, H. (2006).
Event-related oscillations in offspring of alcoholics: neurocognitive disinhibition as a risk for alcoholism.
Biological Psychiatry 59:625-634. (pdf file)

Padmanabhapillai, A., Porjesz, B., Ranganathan, M., Jones, K.A., Chorlian, D.B., Tang, Y., Kamarajan, C., Rangaswamy, M., Stimus, A., and Begleiter, H. (2006).
Suppression of early evoked gamma band response in male alcoholics during a visual oddball task.
International Journal of Psychophysiology 60:15-26. (pdf file)

Padmanabhapillai, A., Tang, Y., Ranganathan, M., Rangaswamy, M., Jones, K.A., Chorlian, D.B., Kamarajan, C., Stimus, A.T., Kuperman, S., Rohrbaugh, J., O'Connor, S.J., Bauer, L.O., Schuckit, M.A., Begleiter, H., and Porjesz, B. (2006).
Evoked gamma band response in male adolescent subjects at high risk for alcoholism during a visual oddball task .
International Journal of Psychophysiology 62:262-271. (pdf file)

In Collaboration:

Agrawal, A., Edenberg, H.J., Foroud, T., Bierut, L.J., Dunne, G., Hinrichs, A.L., Nurnberger, J.I., Crowe, R., Kuperman, S., Schuckit, M.A., Begleiter, H., Porjesz, B., and Dick, D.M. (2006).
Association of GABRA2 with Drug Dependence in the Collaborative Study of the Genetics of Alcoholism Sample.
Behavior Genetics 36:640-50. (pdf file)

Dick, D.M., Agrawal, A., Schuckit, M.A., Bierut, L., Hinrichs, A., Fox, L., Mullaney, J., Cloninger, C.R., Hesselbrock, V., Nurnberger, J.I., Jr., Almasy, L., Foroud, T., Porjesz, B., Edenberg, H., and Begleiter, H. (2006).
Marital status, alcohol dependence, and GABRA2: evidence for gene-environment correlation and interaction.
Journal of Studies on Alcohol 67:185-194. (pdf file)

Dick, D.M., Aliev, F., Bierut, L., Goate, A., Rice, J., Hinrichs, A., Bertelsen, S., Wang, J.C., Dunn, G., Kuperman, S., Schuckit, M., Nurnberger, J., Jr., Porjesz, B., Begleiter, H., Kramer, J., Hesselbrock, V. (2006).
Linkage analyses of IQ in the collaborative study on the genetics of alcoholism (COGA) sample.
Behavior Genetics 36:77-86. (pdf file)

Dick, D.M., Jones, K., Saccone, N., Hinrichs, A., Wang, J.C., Goate, A., Bierut, L., Almasy, L., Schuckit, M., Hesselbrock, V., Tischfield, J., Foroud, T., Edenberg, H., Porjesz, B., and Begleiter, H. (2006).
Endophenotypes successfully lead to gene identification: results from the collaborative study on the genetics of alcoholism.
Behavior Genetics 36:112-126. (pdf file)

Dick, D.M., Bierut, L., Hinrichs, A., Fox, L., Bucholz, K.K., Kramer, J., Kuperman, S., Hesselbrock, V., Schuckit, M., Almasy, L., Tischfield, J., Porjesz, B., Begleiter, H., Nurnberger, J., Jr., Xuei, X., Edenberg, H.J., and Foroud, T. (2006).
The Role of GABRA2 in Risk for Conduct Disorder and Alcohol and Drug Dependence across Developmental Stages.
Behavior Genetics 36:577-590. (pdf file)

Edenberg, H.J., Xuei, X., Chen, H.J., Tian, H., Wetherill, L.F., Dick, D.M., Almasy, L., Bierut, L., Bucholz, K.K., Goate, A., Hesselbrock, V., Kuperman, S., Nurnberger, J., Porjesz, B., Rice, J., Schuckit, M., Tischfield, J., Begleiter, H., and Foroud, T. (2006).
Association of alcohol dehydrogenase genes with alcohol dependence: a comprehensive analysis.
Human Molecular Genetics 15:1539-1549. (pdf file)

Hinrichs, A.L., Wang, J.C., Bufe, B., Kwon, J.M., Budde, J., Allen, R., Bertelsen, S., Evans, W., Dick, D., Rice, J., Foroud, T., Nurnberger, J., Tischfield, J.A., Kuperman, S., Crowe, R., Hesselbrock, V., Schuckit, M., Almasy, L., Porjesz, B., Edenberg, H.J., Begleiter, H., Meyerhof, W., Bierut, L.J., and Goate, A.M. (2006).
Functional variant in a bitter-taste receptor (hTAS2R16) influences risk of alcohol dependence.
American Journal of Human Genetics 78:103-111. (pdf file)

Volkow, N.D., Wang, G.-J., Begleiter, H., Porjesz, B., Fowler, J.S., Telang, F., Wong, C., Ma, Y., Logan, J.,Goldstein, R., Alexoff, B., Thanos, P.K. (2006).
High Levels of Dopamine D2 Receptors.
Archives of General Psychiatry 63:999-1006. (pdf file)

Xuei, X., Dick, D., Flury-Wetherill, L., Tian, H.-J., Agrawal, A., Bierut, L., Goate, A., Bucholz, K., Schuckit, M., Nurnberger, Jr J.I., Tischfield, J., Kuperman, S., Porjesz, B., Begleiter, H., Foroud, T., and Edenberg, H.J. (2006).
Association of the κ-opioid system with alcohol dependence.
Molecular Psychiatry 11:1016-1024. (pdf file)

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Publications in 2005

Kamarajan, C., Porjesz, B., Jones, K.A., Choi, K., Chorlian, D.B., Padmanabhapillai, A., Rangaswamy, M., Stimus, A.T., and Begleiter, H. (2005).
Alcoholism is a disinhibitory disorder: neurophysiological evidence from a Go/No-Go task.
Biological Psychology 69:353-373. (pdf file)

Kamarajan, C., Porjesz, B., Jones, K.A., Chorlian, D.B., Padmanabhapillai, A., Rangaswamy, M., Stimus, A.T., and Begleiter, H. (2005).
Spatial-anatomical mapping of NoGo-P3 in the offspring of alcoholics: evidence of cognitive and neural disinhibition as a risk for alcoholism.
Clinical Neurophysiology 116:1049-1061. (pdf file)

Porjesz, B., Rangaswamy, M., Kamarajan, C., Jones, K.A., Padmanabhapillai, A., and Begleiter, H. (2005).
The utility of neurophysiological markers in the study of alcoholism.
Clinical Neurophysiology 116:993-1018. (pdf file)

In Collaboration:

Corbett, J., Saccone, N.L., Foroud, T., Goate, A., Edenberg, H., Nurnberger, J., Porjesz, B., Begleiter, H., Reich, T., and Rice, J.P. (2005).
A sex-adjusted and age-adjusted genome screen for nested alcohol dependence diagnoses.
Psychiatric Genetics 15:25-30. (pdf file)

Culverhouse, R., Bucholz, K.K., Crowe, R.R., Hesselbrock, V., Nurnberger, J., Jr., Porjesz, B., Schuckit, M.A., Reich, T., Bierut, L.J. (2005).
Long-term Stability of Alcohol and Other Substance Dependence Diagnoses and Habitual Smoking: an evaluation after 5 years.
Archives of General Psychiatry 62:753-760. (pdf file)

Edenberg, H.J., Bierut, L.J., Boyce, P., Cao, M., Cawley, S., Chiles, R., Doheny, K.F., Hansen, M., Hinrichs, T., Jones, K., Kelleher, M., Kennedy, G.C., Liu, G., Marcus, G., McBride, C., Murray, S.S., Oliphant, A., Pettengill, J., Porjesz, B., Pugh, E.W., Rice, J.P., Rubano, T., Shannon, S., Steeke, R., Tischfield, J.A., Tsai, Y.Y., Zhang, C., and Begleiter, H. (2005).
Description of the data from the Collaborative Study on the Genetics of Alcoholism (COGA) and single-nucleotide polymorphism genotyping for Genetic Analysis Workshop 14.
BMC Genetics 6(Supplement 1):S2. (pdf file)

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Publications in 2004

Jones, K.A., Porjesz, B., Almasy, L., Bierut, L., Goate, A., Wang, J.C., Dick, D.M., Hinrichs, A., Kwon, J., Rice, J.P., Rohrbaugh, J., Stock, H., Wu, W., Bauer, L.O., Chorlian, D.B., Crowe, R.R., Edenberg, H.J., Foroud, T., Hesselbrock, V., Kuperman, S., Nurnberger Jr, J., O'Connor, S.J., Schuckit, M.A., Stimus, A.T., Tischfield, J.A., Reich, T., and Begleiter, H. (2004).
Linkage and linkage disequilibrium of evoked EEG oscillations with CHRM2 receptor gene polymorphisms: implications for human brain dynamics and cognition.
International Journal of Psychophysiology 53:75-90. (pdf file)

Kamarajan, C., Porjesz, B., Jones, K.A., Choi, K., Chorlian, D.B., Padmanabhapillai, A., Rangaswamy, M., Stimus, A.T., and Begleiter, H. (2004).
The role of brain oscillations as functional correlates of cognitive systems: a study of frontal inhibitory control in alcoholism.
International Journal of Psychophysiology 51:155-180. (pdf file)

Rangaswamy, M., Porjesz, B., Ardekani, B.A., Choi, S.J., Tanabe, J.L., Lim, K.O., and Begleiter, H. (2004).
A functional MRI study of visual oddball: evidence for frontoparietal dysfunction in subjects at risk for alcoholism.
Neuroimage 21:329-339. (pdf file)

Rangaswamy, M., Porjesz, B., Chorlian, D.B., Wang, K., Jones, K.A., Kuperman, S., Rohrbaugh, J., O'Connor, S.J., Bauer, L.O., Reich, T., and Begleiter, H. (2004).
Resting EEG in offspring of male alcoholics: beta frequencies.
International Journal of Psychophysiology 51:239-251. (pdf file)

In Collaboration:

Bierut, L.J., Rice, J.P., Goate, A., Hinrichs, A.L., Saccone, N.L., Foroud, T., Edenberg, H.J., Cloninger, C.R., Begleiter, H., Conneally, P.M., Crowe, R.R., Hesselbrock, V., Li, T.K., Nurnberger, J.I., Jr., Porjesz, B., Schuckit, M.A., and Reich, T. (2004).
A genomic scan for habitual smoking in families of alcoholics: Common and specific genetic factors in substance dependence.
American Journal of Medical Genetics 124A:19-27. (pdf file)

Dick, D.M., Edenberg, H.J., Xuei, X., Goate, A., Kuperman, S., Schuckit, M., Crowe, R., Smith, T.L., Porjesz, B., Begleiter, H., and Foroud, T. (2004).
Association of GABRG3 with alcohol dependence.
Alcoholism: Clinical and Experimental Research 28:4-9. (pdf file)

Dick, D.M., Li, T.K., Edenberg, H.J., Hesselbrock, V., Kramer, J., Kuperman, S., Porjesz, B., Bucholz, K., Goate, A., Nurnberger, J., and Foroud, T. (2004).
A genome-wide screen for genes influencing conduct disorder.
Molecular Psychiatry 9:81-86. (pdf file)

Edenberg, H.J., Dick, D.M., Xuei, X., Tian, H., Almasy, L., Bauer, L.O., Crowe, R.R., Goate, A., Hesselbrock, V., Jones, K., Kwon, J., Li, T.K., Nurnberger, J.I., Jr., O'Connor, S.J., Reich, T., Rice, J., Schuckit, M.A., Porjesz, B., Foroud, T., and Begleiter, H. (2004).
Variations in GABRA2, encoding the alpha 2 subunit of the GABAA receptor, are associated with alcohol dependence and with brain oscillations.
American Journal of Human Genetics 74:705-714. (pdf file)

Nurnberger, J.I., Jr., Wiegand, R., Bucholz, K., O'Connor, S., Meyer, E.T., Reich, T., Rice, J., Schuckit, M., King, L., Petti, T., Bierut, L., Hinrichs, A.L., Kuperman, S., Hesselbrock, V., Porjesz, B. (2004).
A family study of alcohol dependence: coaggregation of multiple disorders in relatives of alcohol-dependent probands.
Archives of General Psychiatry 61:1246-56. (pdf file)

Wang, J.C., Hinrichs, A.L., Stock, H., Budde, J., Allen, R., Bertelsen, S., Kwon, J.M., Wu, W., Dick, D.M., Rice, J., Jones, K., Nurnberger, J.I., Jr., Tischfield, J., Porjesz, B., Edenberg, H.J., Hesselbrock, V., Crowe, R., Schuckit, M., Begleiter, H., Reich, T., Goate, A.M., and Bierut, L.J. (2004).
Evidence of common and specific genetic effects: association of the muscarinic acetylcholine receptor M2 (CHRM2) gene with alcohol dependence and major depressive syndrome.
Human Molecular Genetics 13:1903-1911. (pdf file)

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Publications in 2003

Chorlian, D.B., Porjesz, B., and Begleiter, H. (2003).
Determination of human EEG alpha entrainment ERD/ERS using the continuous complex wavelet transform.
Proceedings of SPIE 5102:145-55. (pdf file)

Porjesz, B. and Begleiter, H. (2003).
Alcoholism and human electrophysiology.
Alcohol Research & Health 27:153-160. (pdf file)

Rangaswamy, M., Porjesz, B., Chorlian, D.B., Choi, K., Jones, K.A., Wang, K., Rohrbaugh, J., O'Connor, S., Kuperman, S., Reich, T., and Begleiter, H. (2003).
Theta power in the EEG of alcoholics.
Alcoholism: Clinical and Experimental Research 27:607-615. (pdf file)

Suresh, S., Porjesz, B., Chorlian, D.B., Choi, K., Jones, K.A., Wang, K., Stimus, A., and Begleiter, H. (2003).
Auditory P3 in Female Alcoholics.
Alcoholism: Clinical and Experimental Research 27:1064-1074. (pdf file)

In Collaboration:

Ghosh, S., Begleiter, H., Porjesz, B., Chorlian, D.B., Edenberg, H.J., Foroud, T., Goate, A., and Reich, T. (2003).
Linkage Mapping of Beta 2 EEG Waves via Non-Parametric Regression.
American Journal of Medical Genetics 118B:66-71. (pdf file)

Song, J., Koller, D.L., Foroud, T., Carr, K., Zhao, J., Rice, J., Nurnberger, J.I., Jr., Begleiter, H., Porjesz, B., Smith, T.L., Schuckit, M.A., and Edenberg, H.J. (2003).
Association of GABAA receptors and alcohol dependence and the effects of genetic imprinting.
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics 117B:39-45. (pdf file)

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Publications in 2002

Cohen, H.L., Ji, J., Chorlian, D.B., Begleiter, H., and Porjesz, B. (2002).
Alcohol-related ERP changes recorded from different modalities: a topographic analysis.
Alcoholism: Clinical and Experimental Research 26:303-317. (pdf file)

Jones, K., Begleiter, H., Porjesz, B., Wang, K., and Chorlian, D. (2002).
Complexity measures of event related potential surface Laplacian data calculated using the wavelet packet transform.
Brain Topography 14:333-344. (pdf file)

Porjesz, B., Almasy, L., Edenberg, H.J., Wang, K., Chorlian, D.B., Foroud, T., Goate, A., Rice, J.P., O'Connor, S.J., Rohrbaugh, J., Kuperman, S., Bauer, L.O., Crowe, R.R., Schuckit, M.A., Hesselbrock, V., Conneally, P.M., Tischfield, J.A., Li, T.K., Reich, T., and Begleiter, H. (2002).
Linkage disequilibrium between the beta frequency of the human EEG and a GABAA receptor gene locus.
Proceedings of the National Academy of Sciences of the United States of America 99:3729-3733. (pdf file)

Porjesz, B., Begleiter, H., Wang, K., Almasy, L., Chorlian, D.B., Stimus, A.T., Kuperman, S., O'Connor, S.J., Rohrbaugh, J., Bauer, L.O., Edenberg, H.J., Goate, A., Rice, J.P., and Reich, T. (2002).
Linkage and linkage disequilibrium mapping of ERP and EEG phenotypes.
Biological Psychology 61:229-248. (pdf file)

Rangaswamy, M., Porjesz, B., Chorlian, D.B., Wang, K., Jones, K.A., Bauer, L.O., Rohrbaugh, J., O'Connor, S.J., Kuperman, S., Reich, T., and Begleiter, H. (2002).
Beta power in the EEG of alcoholics.
Biological Psychiatry 52:831-842. (pdf file)

In Collaboration:

Ardekani, B.A., Choi, S.J., Hossein-Zadeh, G.A., Porjesz, B., Tanabe, J.L., Lim, K.O., Bilder, R., Helpern, J.A., and Begleiter, H. (2002).
Functional magnetic resonance imaging of brain activity in the visual oddball task.
Cognitive Brain Research 14:347-356. (pdf file)

Bierut, L.J., Saccone, N.L., Rice, J.P., Goate, A., Foroud, T., Edenberg, H., Almasy, L., Conneally, P.M., Crowe, R., Hesselbrock, V., Li, T.K., Nurnberger, J., Jr., Porjesz, B., Schuckit, M.A., Tischfield, J., Begleiter, H., and Reich, T. (2002).
Defining alcohol-related phenotypes in humans. The Collaborative Study on the Genetics of Alcoholism.
Alcohol Research & Health 26:208-213. (pdf file)

Dick, D.M., Nurnberger, J., Jr., Edenberg, H.J., Goate, A., Crowe, R., Rice, J., Bucholz, K.K., Kramer, J., Schuckit, M.A., Smith, T.L., Porjesz, B., Begleiter, H., Hesselbrock, V., and Foroud, T. (2002).
Suggestive linkage on chromosome 1 for a quantitative alcohol-related phenotype.
Alcoholism: Clinical and Experimental Research 26:1453-1460. (pdf file)

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Publications in 2001

Hada, M., Porjesz, B., Chorlian, D.B., Begleiter, H., and Polich, J. (2001).
Auditory P3a deficits in male subjects at high risk for alcoholism.
Biological Psychiatry 49:726-738. (pdf file)

Prabhu, V.R., Porjesz, B., Chorlian, D.B., Wang, K., Stimus, A., and Begleiter, H. (2001).
Visual P3 in female alcoholics.
Alcoholism: Clinical and Experimental Research 25:531-539. (pdf file)

Wang, K., Begleiter, H., and Porjesz, B. (2001).
Warp-averaging event-related potentials.
Clinical Neurophysiology 112:1917-1924. (pdf file)

Zhang, X.L., Cohen, H.L., Porjesz, B., and Begleiter, H. (2001).
Mismatch negativity in subjects at high risk for alcoholism.
Alcoholism: Clinical and Experimental Research 25:330-337. (pdf file)

In Collaboration:

Almasy, L., Porjesz, B., Blangero, J., Goate, A., Edenberg, H.J., Chorlian, D.B., Kuperman, S., O'Connor, S.J., Rohrbaugh, J., Bauer, L.O., Foroud, T., Rice, J.P., Reich, T., and Begleiter, H. (2001).
Genetics of event-related brain potentials in response to a semantic priming paradigm in families with a history of alcoholism.
American Journal of Human Genetics 68:128-135. (pdf file)

Hesselbrock, V., Begleiter, H., Porjesz, B., O'Connor, S., and Bauer, L. (2001).
P300 event-related potential amplitude as an endophenotype of alcoholism-evidence from the collaborative study on the genetics of alcoholism.
Journal of Biomedical Science 8:77-82. (pdf file)

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Publications in 2000

Begleiter, H. and Porjesz, B. (2000).
What is inherited in the predisposition to alcoholism: New model or more muddle?.
Alcoholism: Clinical and Experimental Research 24:246-250. (pdf file)

Hada, M., Porjesz, B., Begleiter, H., and Polich, J. (2000).
Auditory P3a assessment of male alcoholics.
Biological Psychiatry 48:276-286. (pdf file)

Wang, K., Begleiter, H., and Porjesz, B. (2000).
Trilinear modeling of event-related potentials.
Brain Topography 12:263-271. (pdf file)

In Collaboration:

Anokhin, A.P., Vedeniapin, A.B., Sirevaag, E.J., Bauer, L.O., O'Connor, S.J., Kuperman, S., Porjesz, B., Reich, T., Begleiter, H., Polich, J., and Rohrbaugh, J.W. (2000).
The P300 brain potential is reduced in smokers.
Psychopharmacology 149:409-413. (pdf file)

Bierut, L.J., Rice, J.P., Edenberg, H.J., Goate, A., Foroud, T., Cloninger, C.R., Begleiter, H., Conneally, P.M., Crowe, R.R., Hesselbrock, V., Li, T.K., Nurnberger, J.I., Jr., Porjesz, B., Schuckit, M.A., and Reich, T. (2000).
Family-based study of the association of the dopamine D2 receptor gene (DRD2) with habitual smoking.
American Journal of Medical Genetics 90:299-302. (pdf file)

Costa, L., Bauer, L., Kuperman, S., Porjesz, B., O'Connor, S., Hesselbrock, V., Rohrbaugh, J., and Begleiter, H. (2000).
Frontal P300 decrements, alcohol dependence, and antisocial personality disorder.
Biological Psychiatry 47:1064-1071. (pdf file)

Foroud, T., Edenberg, H.J., Goate, A., Rice, J., Flury, L., Koller, D.L., Bierut, L.J., Conneally, P.M., Nurnberger, J.I., Bucholz, K.K., Li, T.K., Hesselbrock, V., Crowe, R., Schuckit, M., Porjesz, B., Begleiter, H., and Reich, T. (2000).
Alcoholism susceptibility loci: confirmation studies in a replicate sample and further mapping.
Alcoholism: Clinical and Experimental Research 24:933-945. (pdf file)

Saccone, N.L., Kwon, J.M., Corbett, J., Goate, A., Rochberg, N., Edenberg, H.J., Foroud, T., Li, T.K., Begleiter, H., Reich, T., and Rice, J.P. (2000).
A genome screen of maximum number of drinks as an alcoholism phenotype.
American Journal of Medical Genetics 96:632-637. (pdf file)

Taber, K.H., Hurley, R.A., Abi-Dargham, A., and Porjesz (2000).
Cortical Inhibition in Alcohol Dependence.
Journal of Neuropsychiatry and Clinical Neurosciences 12:173 - 176. (pdf file)

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Publications in 1999

Begleiter, H. and Porjesz, B. (1999).
What is inherited in the predisposition toward alcoholism? A proposed model.
Alcoholism: Clinical and Experimental Research 23:1125-1135. (pdf file)

Begleiter, H., Reich, T., Nurnberger, J., Jr., Li, T.K., Conneally, P.M., Edenberg, H., Crowe, R., Kuperman, S., Schuckit, M., Bloom, F., Hesselbrock, V., Porjesz, B., Cloninger, C.R., Rice, J., and Goate, A. (1999).
Description of the Genetic Analysis Workshop 11 Collaborative Study on the Genetics of Alcoholism.
Genetic Epidemiology 17 (Suppl 1):S25-S30. (pdf file)

Holguin, S.R., Porjesz, B., Chorlian, D.B., Polich, J., and Begleiter, H. (1999).
Visual P3a in male subjects at high risk for alcoholism.
Biological Psychiatry 46:281-291. (pdf file)

Holguin, S.R., Porjesz, B., Chorlian, D.B., Polich, J., and Begleiter, H. (1999).
Visual P3a in male alcoholics and controls.
Alcoholism: Clinical and Experimental Research 23:582-591. (pdf file)

Ji, J., Porjesz, B., and Begleiter, H. (1999).
Event-related potential index of semantic mnemonic dysfunction in abstinent alcoholics.
Biological Psychiatry 45:494-507. (pdf file)

Ji, J., Porjesz, B., Begleiter, H., and Chorlian, D. (1999).
P300: the similarities and differences in the scalp distribution of visual and auditory modality.
Brain Topography 11:315-327. (pdf file)

Wang, K. and Begleiter, H. (1999).
Local polynomial estimate of surface Laplacian.
Brain Topography 12:19-29. (pdf file)

In Collaboration:

Almasy, L., Porjesz, B., Blangero, J., Chorlian, D.B., O'Connor, S.J., Kuperman, S., Rohrbaugh, J., Bauer, L.O., Reich, T., Polich, J., and Begleiter, H. (1999).
Heritability of event-related brain potentials in families with a history of alcoholism.
American Journal of Medical Genetics 88:383-390. (pdf file)

Neuman, R.J., Todd, R.D., Heath, A.C., Reich, W., Hudziak, J.J., Bucholz, K.K., Madden, P.A., Begleiter, H., Porjesz, B., Kuperman, S., Hesselbrock, V., and Reich, T. (1999).
Evaluation of ADHD typology in three contrasting samples: a latent class approach.
Journal of the American Academy of Child and Adolescent Psychiatry 38:25-33. (pdf file)

Stassen, H.H., Begleiter, H., Porjesz, B., Rice, J., Scharfetter, C., and Reich, T. (1999).
Structural decomposition of genetic diversity in families with alcoholism.
Genetic Epidemiology 17 Suppl 1:S325-330. (pdf file)

Williams, J.T., Begleiter, H., Porjesz, B., Edenberg, H.J., Foroud, T., Reich, T., Goate, A., Van Eerdewegh, P., Almasy, L., and Blangero, J. (1999).
Joint multipoint linkage analysis of multivariate qualitative and quantitative traits. II. Alcoholism and event-related potentials.
American Journal of Human Genetics 65:1148-1160. (pdf file)

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Publications in 1998

Begleiter, H., Porjesz, B., Reich, T., Edenberg, H.J., Goate, A., Blangero, J., Almasy, L., Foroud, T., Van Eerdewegh, P., Polich, J., Rohrbaugh, J., Kuperman, S., Bauer, L.O., O'Connor, S.J., Chorlian, D.B., Li, T.K., Conneally, P.M., Hesselbrock, V., Rice, J.P., Schuckit, M.A., Cloninger, R., Nurnberger, J., Jr., Crowe, R., and Bloom, F.E. (1998).
Quantitative trait loci analysis of human event-related brain potentials: P3 voltage.
Electroencephalography and Clinical Neurophysiology 108:244-250. (pdf file)

Cohen, H.L., Porjesz, B., Stimus, A.T., and Begleiter, H. (1998).
Effects of ethanol on temporal recovery of auditory-evoked potentials in individuals at risk for alcoholism.
Alcoholism: Clinical and Experimental Research 22:945-953. (pdf file)

Ji, J., Porjesz, B., and Begleiter, H. (1998).
ERP components in category matching tasks.
Electroencephalography and Clinical Neurophysiology 108:380-389. (pdf file)

Ji, J., Porjesz, B., Chorlian, D., and Begleiter, H. (1998).
Event-related potentials during digit recognition tasks.
Brain Research Cognitive Brain Research 7:179-190. (pdf file)

Porjesz, B. and Begleiter, H. (1998).
Genetic basis of event-related potentials and their relationship to alcoholism and alcohol use.
Journal of Clinical Neurophysiology 15:44-57. (pdf file)

Porjesz, B., Begleiter, H., Reich, T., Van Eerdewegh, P., Edenberg, H.J., Foroud, T., Goate, A., Litke, A., Chorlian, D.B., Stimus, A., Rice, J., Blangero, J., Almasy, L., Sorbell, J., Bauer, L.O., Kuperman, S., O'Connor, S.J., and Rohrbaugh, J. (1998).
Amplitude of visual P3 event-related potential as a phenotypic marker for a predisposition to alcoholism: preliminary results from the COGA Project. Collaborative Study on the Genetics of Alcoholism.
Alcoholism: Clinical and Experimental Research 22:1317-1323. (pdf file)

Wang, K., Begleiter, H., and Porjesz, B. (1998).
Spatial enhancement of event-related potentials using multiresolution analysis.
Brain Topography 10:191-200. (pdf file)

Wang, K., Begleiter, H., and Porjesz, B. (1998).
Analysis of repeated measurements in curves (brain potentials).
Proceedings of the Section of Statistics in Epidemiology of the American Statistical Association 122-127. (pdf file)

In Collaboration:

Bierut, L.J., Dinwiddie, S.H., Begleiter, H., Crowe, R.R., Hesselbrock, V., Nurnberger, J.I., Jr., Porjesz, B., Schuckit, M.A., and Reich, T. (1998).
Familial transmission of substance dependence: alcohol, marijuana, cocaine, and habitual smoking: a report from the Collaborative Study on the Genetics of Alcoholism.
Archives of General Psychiatry 55:982-988. (pdf file)

Cloniger, C.R., Van Eerdewegh, P., Goate, A., Edenberg, H.J., Blangero, J., Hesselbrock, V., Reich, T., Nurnberger, J.I., Schuckit, M., Porjesz, B., Crowe, R., Rice, J.P., Foroud, T., Przybeck, T.R., Almasy, L., Buchholz, K., Wu, W., Shears, S., Carr, K., Crose, C., Willig, C., Zhou, J., Tischfield, J.A., Li, T.-K., Conneally, P.M., and Begleiter, H. (1998).
Anxiety Proneness linked to epistatic loci in genome scan of human personality traits.
American Journal of Medical Genetics 81:313-317. (pdf file)

Edenberg, H.J., Foroud, T., Koller, D.L., Goate, A., Rice, J., Van Eerdewegh, P., Reich, T., Cloninger, C.R., Nurnberger, J.I., Jr., Kowalczuk, M., Wu, B., Li, T.K., Conneally, P.M., Tischfield, J.A., Wu, W., Shears, S., Crowe, R., Hesselbrock, V., Schuckit, M., Porjesz, B., and Begleiter, H. (1998).
A family-based analysis of the association of the dopamine D2 receptor (DRD2) with alcoholism.
Alcoholism: Clinical and Experimental Research 22:505-512. (pdf file)

Edenberg, H.J., Foroud, T., Koller, D.L., Goate, A., Rice, J., Van Eerdewegh, P., Reich, T., Cloninger, C.R., Nurnberger, J.I., Jr., Kowalczuk, M., Wu, B., Li, T.K., Conneally, P.M., Tischfield, J.A., Wu, W., Shears, S., Crowe, R., Hesselbrock, V., Schuckit, M., Porjesz, B., and Begleiter, H. (1998).
Letter to the editor, Science, in response to previously published letter to the editor by Dr. Ernest Noble, re: A family-based analysis of the association of the dopamine D2 receptor (DRD2) with alcoholism.
Science 282:1265. (pdf file)

Edenberg, H.J., Reynolds, J., Koller, D.L., Begleiter, H., Bucholz, K.K., Conneally, P.M., Crowe, R., Goate, A., Hesselbrock, V., Li, T.K., Nurnberger, J.I., Jr., Porjesz, B., Reich, T., Rice, J.P., Schuckit, M., Tischfield, J.A., and Foroud, T. (1998).
A family-based analysis of whether the functional promoter alleles of the serotonin transporter gene HTT affect the risk for alcohol dependence.
Alcoholism: Clinical and Experimental Research 22:1080-1085. (pdf file)

Foroud, T., Bucholz, K.K., Edenberg, H.J., Goate, A., Neuman, R.J., Porjesz, B., Koller, D.L., Rice, J., Reich, T., Bierut, L.J., Cloninger, C.R., Nurnberger, J.I., Jr., Li, T.K., Conneally, P.M., Tischfield, J.A., Crowe, R., Hesselbrock, V., Schuckit, M., and Begleiter, H. (1998).
Linkage of an alcoholism-related severity phenotype to chromosome 16.
Alcoholism: Clinical and Experimental Research 22:2035-2042. (pdf file)

Reich, T., Edenberg, H.J., Goate, A., Williams, J.T., Rice, J.P., Van Eerdewegh, P., Foroud, T., Hesselbrock, V., Schuckit, M.A., Bucholz, K., Porjesz, B., Li, T.K., Conneally, P.M., Nurnberger, J.I., Jr., Tischfield, J.A., Crowe, R.R., Cloninger, C.R., Wu, W., Shears, S., Carr, K., Crose, C., Willig, C., and Begleiter, H. (1998).
Genome-wide search for genes affecting the risk for alcohol dependence.
American Journal of Medical Genetics 81:207-215. (pdf file)

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Publications in 1997

Cohen, H.L., Porjesz, B., Begleiter, H., and Wang, W. (1997).
Neurophysiological correlates of response production and inhibition in alcoholics.
Alcoholism: Clinical and Experimental Research 21:1398-1406. (pdf file)

Cohen, H.L., Porjesz, B., Begleiter, H., and Wang, W. (1997).
Neuroelectric correlates of response production and inhibition in individuals at risk to develop alcoholism.
Biological Psychiatry 42:57-67. (pdf file)

Porjesz, B. and Begleiter, H. (1997).
Event-related potentials in COA's.
Alcohol Health and Research World 21:236-240. (pdf file)

Zhang, X.L., Begleiter, H., and Porjesz, B. (1997).
Do chronic alcoholics have intact implicit memory? An ERP study.
Electroencephalography and Clinical Neurophysiology 103:457-473. (pdf file)

Zhang, X.L., Begleiter, H., Porjesz, B., and Litke, A. (1997).
Electrophysiological evidence of memory impairment in alcoholic patients.
Biological Psychiatry 42:1157-1171. (pdf file)

Zhang, X.L., Begleiter, H., Porjesz, B., and Litke, A. (1997).
Reflection of working memory: ERP mnemonic effects.
Electroencephalography and Clinical Neurophysiology 104:546-554. (pdf file)

Zhang, X.L., Begleiter, H., Porjesz, B., and Litke, A. (1997).
Visual object priming differs from visual word priming: an ERP study.
Electroencephalography and Clinical Neurophysiology 102:200-215. (pdf file)

Zhang, X.L., Begleiter, H., and Porjesz, B. (1997).
Is working memory intact in alcoholics? An ERP study.
Psychiatry Research 75:75-89. (pdf file)

In Collaboration:

Koziol, J., Alexander, J., Bauer, L.O., Kuperman, S., Morzorati, O Connor, S.J., Porjesz, B., Stewart, P., and Begleiter, H. (1997).
A graphical technique for displaying correlation matrices.
The American Statistician 51:301-304. (pdf file)

Polich, J., Alexander, J., Kuperman, S., Morzorati, S., O'Connor, S.J., Porjesz, B., Rohrbaugh, J., and Begleiter, H. (1997).
P300 topography of amplitude/latency correlations.
Brain Topography 9:275-282. (pdf file)

Rohrbaugh, J.W., Dunham, D.N., Stewart, P.A., Bauer, L.O., Kuperman, S., O'Connor, S.J., Porjesz, B., and Begleiter, H. (1997).
Slow brain potentials in a visual-spatial memory task: topographic distribution and inter-laboratory consistency.
International Journal of Psychophysiology 25:111-122. (pdf file)

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Publications in 1996

Begleiter, H. (1996).
The Collaborative Study on the Genetics of Alcoholism: Overview
Alcohol Health & Research World 19:228-236. (pdf file)

Begleiter, H. (1996).
A genomic survey of alcohol dependence and related phenotypes: Results from the collaborative study on the genetics of alcoholism (COGA).
Alcoholism: Clinical and Experimental Research 20:133A-137A. (pdf file)

Begleiter, H. and Kissin, B. (eds.) (1996).
Alcohol and Alcoholism, Vol. 2, The Pharmacology of Alcohol and Alcohol Dependence. Oxford University Press, New York.

Cohen, H.L., Porjesz, B., and Begleiter, H. (1996).
Temporal recovery of auditory evoked potentials in individuals at risk for alcoholism.
Alcohol 13:333-339. (pdf file)

Porjesz, B. and Begleiter, H. (1996).
The Collaborative Study on the Genetics of Alcoholism: Neurophysiological component
Alcohol Health & Research World 19:228-236. (pdf file)

Ramachandran, G., Porjesz, B., Begleiter, H., and Litke, A. (1996).
A simple auditory oddball task in young adult males at high risk for alcoholism.
Alcoholism: Clinical and Experimental Research 20:9-15. (pdf file)

In Collaboration:

Alexander, J.E., Bauer, L.O., Kuperman, S., Rohrbaugh, J., Morzorati, S., O'Connor, S.J., Porjesz, B., Begleiter, H., and Polich, J. (1996).
Hemispheric differences for P300 amplitude from an auditory oddball task.
International Journal of Psychophysiology 21:189-196. (pdf file)

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Publications in 1995

Begleiter, H. and Kissin, B., (eds.) (1995).
Alcohol and Alcoholism, Vol. 1, The Genetics of Alcoholism. Oxford University Press, New York.

Begleiter, H., Porjesz, B., and Wang, W. (1995).
Event-related brain potentials differentiate priming and recognition to familiar and unfamiliar faces.
Electroencephalography and Clinical Neurophysiology 94:41-49. (pdf file)

Begleiter, H., Reich, T., Hesselbrock, V.M., Porjesz, B., Li, T.K., Schuckit, M.A., Edenberg, H.J., and Rice, J.P. (1995).
The Collaborative Study on the Genetics of Alcoholism.
Alcohol Health & Research World 19:228-236. (pdf file)

Chorlian, D.B., Porjesz, B., and Cohen, H.L. (1995).
Measuring electrical activity of the brain: ERP mapping in alcohol research.
Alcohol Health & Research World 19:315-320. (pdf file)

Cohen, H.L., Wang, W., Porjesz, B., and Begleiter, H. (1995).
Auditory P300 in young alcoholics: regional response characteristics.
Alcoholism: Clinical and Experimental Research 19:469-475. (pdf file)

Porjesz, B., and Begleiter, H. (1995).
Event-related potentials and cognitive function in alcoholism.
Alcohol Health and Research World 19:108-112. (pdf file)

Zhang, X.L., Begleiter, H., Porjesz, B., Wang, W., and Litke, A. (1995).
Event related potentials during object recognition tasks.
Brain Research Bulletin 38:531-538. (pdf file)

In Collaboration:

Alexander, J.E., Porjesz, B., Bauer, L.O., Kuperman, S., Morzorati, S., O'Connor, S.J., Rohrbaugh, J., Begleiter, H., and Polich, J. (1995).
P300 hemispheric amplitude asymmetries from a visual oddball task.
Psychophysiology 32:467-475. (pdf file)

Kuperman, S., Porjesz, B., Arndt, S., Bauer, L., Begleiter, H., Cizadlo, T., O'Connor, S., and Rohrbaugh, J. (1995).
Multi-center N400 ERP consistency using a primed and unprimed word paradigm.
Electroencephalography and Clinical Neurophysiology 94:462-470. (pdf file)

Rice, J.P., Reich, T., Bucholz, K.K., Neuman, R.J., Fishman, R., Rochberg, N., Hesselbrock, V.M., Nurnberger, J.I., Jr., Schuckit, M.A., and Begleiter, H. (1995).
Comparison of direct interview and family history diagnoses of alcohol dependence.
Alcoholism: Clinical and Experimental Research 19:1018-1023. (pdf file)

Volkow, N.D., Wang, G.J., Begleiter, H., Hitzemann, R., Pappas, N., Burr, G., Pascani, K., Wong, C., Fowler, J.S., and Wolf, A.P. (1995).
Regional brain metabolic response to Lorazepam in subjects at risk for alcoholism.
Alcoholism: Clinical and Experimental Research 19:510-516. (pdf file)

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Publications in 1994

Cohen, H.L., Wang, W., Porjesz, B., Bauer, L., Kuperman, S., O'Connor, S.J., Rohrbaugh, J., and Begleiter, H. (1994).
Visual P300: an interlaboratory consistency study.
Alcohol 11:583-587. (pdf file)

Hertz, S., Porjesz, B., Begleiter, H., and Chorlian, D. (1994).
Event-related potentials to faces: the effects of priming and recognition.
Electroencephalography and Clinical Neurophysiology 92:342-351. (pdf file)

Wang, W., Begleiter, H., and Porjesz, B. (1994).
Surface energy, its density and distance: new measures with application to human cerebral potentials.
Brain Topography 6:193-202. (pdf file)

Wang, W., Begleiter, H., and Porjesz, B. (1994).
Multivariate composite estimators: new ways to track signals with application to human cerebral potentials.
Brain Topography 7:9-15. (pdf file)

Wang, W., Begleiter, H., and Porjesz, B. (1994).
Localization of multiple dipole sources of human cerebral potential based on scd and a model selection criterion.
Proceedings of the Section of Statistics in Epidemiology of the American Statistical Association 217-222. (pdf file)

In Collaboration:

Alexander, J.E., Polich, J., Bloom, F.E., Bauer, L.O., Kuperman, S., Rohrbaugh, J., Morzorati, S., O'Connor, S.J., Porjesz, B., and Begleiter, H. (1994).
P300 from an auditory oddball task: inter-laboratory consistency.
International Journal of Psychophysiology 17:35-46. (pdf file)

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Publications in 1993

Begleiter, H., Porjesz, B., and Wang, W. (1993).
A neurophysiologic correlate of visual short-term memory in humans.
Electroencephalography and Clinical Neurophysiology 87:46-53. (pdf file)

Cohen, H.L., Porjesz, B., and Begleiter, H. (1993).
Ethanol-induced alterations in electroencephalographic activity in adult males.
Neuropsychopharmacology 8:365-370. (pdf file)

Cohen, H.L., Porjesz, B., and Begleiter, H. (1993).
The effects of ethanol on EEG activity in males at risk for alcoholism.
Electroencephalography and Clinical Neurophysiology 86:368-376. (pdf file)

Realmuto, G., Begleiter, H., Odencrantz, J., and Porjesz, B. (1993).
Event-related potential evidence of dysfunction in automatic processing in abstinent alcoholics.
Biological Psychiatry 33:594-601. (pdf file)

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Publications in 1992

Zaninelli, R.M., Porjesz, B., and Begleiter, H. (1992).
The Tridimensional Personality Questionnaire in males at high and low risk for alcoholism.
Alcoholism: Clinical and Experimental Research 16:68-70. (pdf file)

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Publications in 1991

Cohen, H.L., Porjesz, B., and Begleiter, H. (1991).
EEG characteristics in males at risk for alcoholism.
Alcoholism: Clinical and Experimental Research 15:858-861. (pdf file)

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Publications in 1990

Begleiter, H. and Porjesz, B. (1990).
Event-related potentials in populations at risk for alcoholism.
Electroencephalography and Clinical Neurophysiology Supplement 41:177-182. (pdf file)

Begleiter, H. and Porjesz, B. (1990).
Neuroelectric processes in individuals at risk for alcoholism.
Alcohol and Alcoholism 25:251-256. (pdf file)

Porjesz, B. and Begleiter, H. (1990).
Event-related potentials in individuals at risk for alcoholism.
Alcohol 7:465-469. (pdf file)

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Publications in 1988

Begleiter, H. and Porjesz, B. (1988).
Potential biological markers in individuals at high risk for developing alcoholism.
Alcoholism: Clinical and Experimental Research 12:488-493. (pdf file)

Rawlings, R.R., Eckardt, M.J., and Begleiter, H. (1988).
Multivariate spectral methods for the analysis of event-related brain potentials.
Computers and Biomedical Research 21:117-128. (pdf file)

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Publications in 1987

Begleiter, H., Porjesz, B., and Bihari, B. (1987).
Auditory brainstem potentials in sons of alcoholic fathers.
Alcoholism: Clinical and Experimental Research 11:477-480. (pdf file)

Begleiter, H., Porjesz, B., Rawlings, R., and Eckardt, M. (1987).
Auditory recovery function and P3 in boys at high risk for alcoholism.
Alcohol 4:315-321. (pdf file)

Brecher, M., Porjesz, B., and Begleiter, H. (1987).
Late positive component amplitude in schizophrenics and alcoholics in two different paradigms.
Biological Psychiatry 22:848-856. (pdf file)

Brecher, M., Porjesz, B., and Begleiter, H. (1987).
The N2 component of the event-related potential in schizophrenic patients.
Electroencephalography and Clinical Neurophysiology 66:369-375. (pdf file)

Porjesz, B., Begleiter, H., Bihari, B., and Kissin, B. (1987).
Event-related brain potentials to high incentive stimuli in abstinent alcoholics.
Alcohol 4:283-287. (pdf file)

Porjesz, B., Begleiter, H., Bihari, B., and Kissin, B. (1987).
The N2 component of the event-related brain potential in abstinent alcoholics.
Electroencephalography and Clinical Neurophysiology 66:121-131. (pdf file)

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Publications in 1986

Rawlings, R.R., Rohrbaugh, J.W., Begleiter, H., and Eckardt, M. (1986).
Spectral methods for principal components analysis of event-related brain potentials. (pdf file)
Computers and Biomedical Research 19:497-507.

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Publications in 1985

Begleiter, H. (1985).
Evoked brain potentials in children of alcoholics. Early Identification of Alcohol Abuse.
NIAAA Research Monograph #15/16, August.

Brecher, M. and Begleiter, H. (1985).
Brain stem auditory evoked potentials in unmedicated schizophrenic patients.
Biological Psychiatry 20:199-202. (pdf file)

Porjesz, B. and Begleiter, H. (1985).
The use of event-related potentials in the study of alcoholism: implications for the study of drugs of abuse.
NIDA Research Monograph 62:77-99. (pdf file)

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Publications in 1984

Begleiter, H., Porjesz, B., Bihari, B., and Kissin, B. (1984).
Event-related potentials in boys at risk for alcoholism.
Science 225:1493-1496. (pdf file)

Rawlings, R.R., Eckardt, M.J., and Begleiter, H. (1984).
Multivariate time series discrimination in the spectral domain.
Computers and Biomedical Research 17:352-361. (pdf file)

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Publications in 1983

Begleiter, H., Porjesz, B., Chou, C.L., and Aunon, J.I. (1983).
P3 and stimulus incentive value.
Psychophysiology 20:95-101. (pdf file)

Brecher, M. and Begleiter, H. (1983).
Event-related potentials to high incentive stimuli in unmedicated schizophrenic patients.
Biological Psychiatry 18:661-674. (pdf file)

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Publications in 1982

Porjesz, B. and Begleiter, H. (1982).
Evoked brain potential deficits in alcoholism and aging.
Alcoholism: Clinical and Experimental Research 6:53-63. (pdf file)

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Publications in 1981

Begleiter, H. (1981).
Brain dysfunction and alcoholism: problems and prospects.
Alcoholism: Clinical and Experimental Research 5:264-266. (pdf file)

Begleiter, H., Porjesz, B., and Chou, C.L. (1981).
Auditory brainstem potentials in chronic alcoholics.
Science 211:1064-1066. (pdf file)

Begleiter, H., Porjesz, B., and Tenner, M. (1981).
Ereignisbezogene Hirnpotentiale und Computer-Tomographie bei chronischen Alkoholikern.
Wiener Zeitschrift für Suchtforschung 2:3-6. (pdf file)

Porjesz, B. and Begleiter, H. (1981).
Human evoked brain potentials and alcohol.
Alcoholism: Clinical and Experimental Research 5:304-317. (pdf file)

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Publications in 1980

Begleiter, H., Porjesz, B., and Tenner, M. (1980).
Neuroradiological and neurophysiological evidence of brain deficits in chronic alcoholics.
Acta Psychiatrica Scandinavica Supplementum 286:3-13. (pdf file)

Porjesz, B., Begleiter, H., and Samuelly, I. (1980).
Cognitive deficits in chronic alcoholics and elderly subjects assessed by evoked brain potentials.
Acta Psychiatrica Scandinavica Supplementum 286:15-29. (pdf file)

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Publications in 1979

Begleiter, H. and Porjesz, B. (1979).
Persistence of a "subacute withdrawal syndrome" following chronic ethanol intake.
Drug and Alcohol Dependence 4:353-357. (pdf file)

Denoble, V.J. and Begleiter, H. (1979).
Impairment of acquisition of a DRL schedule following prolonged ethanol consumption.
Pharmacology, Biochemistry and Behavior 10:393-396. (pdf file)

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Publications between 1976 and 1978

Denoble, V.J. and Begleiter, H. (1978).
Alcohol self-administration in monkeys (Macaca Radiata): the effects of prior alcohol exposure.
Pharmacology, Biochemistry and Behavior 8:391-397. (pdf file)

DeNoble, V. and Begleiter, H. (1977).
Changes in fixed-ratio performance and blood alcohol levels in monkeys.
Psychopharmacology 55:213-216. (pdf file)

Denoble, V. and Begleiter, H. (1976).
Response suppression on a mixed schedule of reinforcement during alcohol withdrawal.
Pharmacology, Biochemistry and Behavior 5:227-229. (pdf file)

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