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Collaborative Study on the Genetics of Alcoholism

 

Reviewed COGA articles (SAGE articles are marked with ***)

 A complete list of a all COGA publications as a pdf-file (last change 2014-10-15).

 

1990
1991
1992
1993
1994
1995
1996
1997
1998
1999
1
0
1
0
6
16
13
13
20
18
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
15
15
19
16
16
24
34
25
22
17
2010
2011
2012
2013
2014
 
 
 
 
TOTAL
27
20
29
19
28
 
 
 
 
414

The downloadable pdf files are for you personal, scientific use only!

2014

Agrawal, A., Lynskey, M.T., Bucholz, K.K., Kapoor, M., Almasy, L., Dick, D.M., Edenberg, H.J., Foroud, T., Goate, A., Hancock, D.B., Hartz, S., Johnson, E.O., Hesselbrock, V., Kramer, J.R., Kuperman, S., Nurnberger Jr., J.I., Schuckit, M., and Bierut, L.J. (2014).
DSM-5 cannabis use disorder: A phenotypic and genomic perspective.
Drug and Alcohol Dependence 134(1):362-369. PMID: 24315570. PMCID: PMC3943464. (pdf file)


Aliev, F., Wetherill, L., Bierut, L., Bucholz, K.K., Edenberg, H.J., Foroud, T., and Dick, D.M. (2014).
Genes associated with alcohol-outcomes show enrichment of effects with broad externalizing and impulsivity phenotypes in an independent sample
Journal of Studies on Alcohol and Drugs xx(xx)xxx-xxx.

Chen, L.-S., Hung, R.J., Baker, T., Horton, A., Culverhouse, R., Saccone, N., Cheng, I., Deng, B., Han, Y., Hansen, H.M., Horsman, J., Kim, C. Lutz, S., Rosenberger, A., Aben, K.K., Breslau, N., Chang, S.-C., Dieffenbach, A.K., Dienemann, H., Frederiksen, B., Han, J., Hatsukami, D.K., Johnson, E.O., Pande, M., Wrensch, M.R., McLaughlin, J., Skaug, V., van der Heijden, H.F., Wamplfer, J., Wenzlaff, A., Woll, P., Zienolddiny, S., Bickeböller, H., Brenner, H., Duell, E.J., Haugen, A., Heinrich, J., Hokanson, J.E., Hunter, D., Kiemeney, L.A., Lazarus, P., Le Marchand, L., Liu, G., Mayordomo, J., Risch, A., Schwartz, A.G., Teare, D., Wu, X., Wiencke, J.K., Yang, P., Zhang, Z.-F., Spitz, M.R., Kraft, P., Amos, C.I., Bierut, L.J. (2014).
CHRNA5 Risk Variant Predicts Earlier Age at Lung Cancer Diagnosis and Delayed Smoking Cessation - A Meta-analysis.
Journal of the National Cancer Institute xx(xx)xxx-xxx.

Conner, K., Bossarte, R., Lu, N., Kaukeinen, K., Chan, G., Wyman, P., Tu, X., Goldston, D., Houston, R., Bucholz, K., and Hesselbrock, V. (2014).
Parent- and child psychopathology and suicide attempts among children of parents with alcohol use disorder.
Archives of Suicide Research 18(2):117-130. PMID: 24716789.
PMCID: PMC4059391. (pdf file)

Conner, K.R., Wyman, P., Goldston, D.B., Bossarte, R.M., Lu, N., Kaukeinen, K., Tu, X.M., Houston, R.J., Lamis, D.A., Chan, G., Bucholz, K.K., and Hesselbrock, V.M. (2014).
Two studies of connectedness to parents and suicidal thoughts and behavior in children and adolescents.
Journal of Clinical Child Adolescent Psychology xx(x):xxx-xxx.

Culverhouse, R.C., Johnson, E.O., Breslau, N., Hatsukami, D.K., Sadler, B., Brooks, A.I., Hesselbrock, V.M., Schuckit, M.A., Tischfield, J.A., Goate, A.M., Saccone, N.L., and Bierut, L.J. (2014).
Multiple distinct CHRNB3-CHRNA6 variants are genetic risk factors for nicotine dependence in African Americans and European Americans.
Addiction 109(5):814-822. PMID: 24401102. PMCID: PMC3984604. (pdf file)

Dick, D.M., Cho, S.B., Latendresse, S.J., Aliev, F., Nurnberger, Jr, J.I., Edenberg, H.J., Schuckit, M., Hesselbrock, V.M., Porjesz, B., Bucholz, K., Wang, J.-C., Goate, A., Kramer, J.R., and Kuperman, S. (2014).
Genetic influences on alcohol use across stages of development: GABRA2 and longitudinal trajectories of drunkenness from adolescence to young adulthood.
Addiction Biology xx(x):xxx-xxx. PMID: 23692184. (pdf file)


Edenberg, H.J. and Foroud, T. (2014).
Genetics of alcoholism.
In: Sullivan, E.V. and Pfefferbaum, A. (eds.), Handbook of Clinical Neurology, Volume 125 (3rd edition), Alcohol and the Nervous System.
Elsevier B.V., The Netherlands, ISBN-13: 978-0444626196
Handbook of Clinical Neurology 125C:561-571. PMID: 25307596.

*** Gelernter, J., Kranzler, H.R., Sherva, R., Almasy, L., Koesterer, R., Smith, A.H., Anton, R., Preuss, U.W., Ridinger, M., Rujescu, D., Wodarz, N., Zill, P., Zhao, H., and Farrer, L.A. (2014).
Genome-wide association study of alcohol dependence: significant findings in African- and European-Americans including novel risk loci.
Molecular Psychiatry 19(1):41-49. PMID: 24166409. (pdf file)

*** Gelernter, J., Kranzler, H.R., Sherva, R., Koesterer, R., Almasy, L., Zhao, H.Y., and Farrer, L.A. (2014).
Genome-Wide Association Study of Opioid Dependence: Multiple Associations Mapped to Calcium and Potassium Pathways
Biological Psychiatry, 76(1):66-74. PMID: 24143882. PMCID: PMC3992201. (pdf file)

Glass, J.E., Williams, E.C., and Bucholz K.K. (2014).
Psychiatric comorbidity and perceived alcohol stigma in a nationally representative sample of individuals with DSM-5 alcohol use disorder.
Alcoholism: Clinical and Experimental Research 38(6):1697-1705. PMID: 24848495. PMCID: PMC4059348. (pdf file)

Haller, G., Kapoor, M., Budde, J., Xuei, X., Edenberg, H., Nurnberger, J., Kramer, J., Brooks, A., Tischfield, J., Almasy, L., Agrawal, A., Bucholz, K., Rice, J., Saccone, N., Bierut, L., and Goate, A. (2014).
Rare missense variants in CHRNB3 and CHRNA3 are associated with risk of alcohol and cocaine dependence.
Human Molecular Genetics 23(3):810-819. PMID: 24057674. PMCID: PMC3888263.
(pdf file)

Hartz, S.M., Pato, C.N., Medeiros, H, Cavazos-Rehg, P., Sobell, J.L., Knowles, J.A., Bierut, L.J., Pato, M.T., and Genomic Psychiatry Cohort Consortium (2014).
Comorbidity of Severe Psychotic Disorders With Measures of Substance Use.
JAMA Psychiatry 71(3):248-254. PMID: 24382686. PMCID: PMC4060740. (pdf file)

Kapoor, M., Wang, J.-C., Wetherill, L., Le, N., Bertelsen, S., Hinrichs, A.L., Budde, J., Agrawal, A., Almasy, L., Bucholz, K., Dick, D.M., Harari, O., Xiaoling, X., Hesselbrock, V., Kramer, J., Nurnberger Jr, J.I., Rice, J., Schuckit, M., Tischfield, J., Porjesz, B., Edenberg, H.J., Bierut, L., Foroud, T., and Goate, A. (2014).
Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.
Drug and Alcohol Dependence 142:56-62. PMID: 24962325 (pdf file)

McClintick, J.N., Brooks, A.I., Deng, L., Liang, L., Wang, J.C., Kapoor, M., Xuei, X., Foroud, T., Tischfield, J.A., and Edenberg, H.J. (2014).
Ethanol treatment of lymphoblastoid cell lines from alcoholics and non-alcoholics causes many subtle changes in gene expression
Alcohol 48(6):603-610. PMID: 25129674. (pdf file)

McCutcheon, V.V., Kramer, J.R., Edenberg, H.J., Nurnberger, J.I., Kuperman, S., Schuckit, M.A., Heath, A.C., and Bucholz, K.K. (2014).
Social Contexts of Remission from DSM-5 Alcohol Use Disorder in a High-Risk Sample.
Alcoholism: Clinical and Experimental Research 38(7):2015-2023. PMID: 24942361. PMCID: PMC4107016. (pdf file)

Olfson, E., Edenberg, H.J., Nurnberger, J. Jr, Agrawal, A., Bucholz, K.K., Almasy, L.A., Chorlian, D., Dick, D.M., Hesselbrock, V.M., Kramer, J.R., Kuperman, S., Porjesz, B., Schuckit, M.A., Tischfield, J.A., Wang, J.C., Wetherill, L., Foroud, T.M., Rice, J., Goate, A., and Bierut, L.J. (2014).
An ADH1B Variant and Peer Drinking in Progression to Adolescent Drinking Milestones: Evidence of a Gene-by-Environment Interaction.
Alcoholism: Clinical and Experimental Research xx(x):xxx-xxx. PMID: 25257461 (pdf file)


*** Perry, J.R.,Day, F., Elks,C.E., Sulem,P.,Thompson, D.J., Ferreira, T.,He, C., Chasman, D.I., Esko, T., Thorleifsson, G., Albrecht, E., Ang, W.Q., Corre, T., Cousminer, D.L., Feenstra, B., Franceschini, N., Ganna, A., Johnson, A.D., Kjellqvist, S., Lunetta, K.L., McMahon, G., Nolte, I.M., Paternoster, L., Porcu, E., Smith, A.V., Stolk, L., Teumer, A., Tšernikova, N., Tikkanen, E., Ulivi, S., Wagner, E.K., Amin, N., Bierut, L.J., Byrne, E.M., Hottenga, J.J., Koller, D.L., Mangino, M., Pers, T.H., Yerges-Armstrong, L.M., Hua Zhao, J., Andrulis, I.L., Anton-Culver, H., Atsma, F., Bandinelli, S., Beckmann, M.W., Benitez, J., Blomqvist, C., Bojesen, S.E., Bolla, M.K., Bonanni, B., Brauch, H., Brenner, H., Buring, J.E., Chang-Claude, J., Chanock, S., Chen, J., Chenevix-Trench, G., Collée, J.M., Couch, F.J., Couper, D., Coviello, A.D., Cox, A., Czene, K., D'adamo, A.P., Davey Smith, G., De Vivo, I., Demerath, E.W., Dennis, J., Devilee, P., Dieffenbach, A.K., Dunning, A.M., Eiriksdottir, G., Eriksson, J.G., Fasching, P.A., Ferrucci, L., Flesch-Janys, D., Flyger, H., Foroud, T., Franke, L., Garcia, M.E., García-Closas, M., Geller, F., de Geus, E.E., Giles, G.G., Gudbjartsson, D.F., Gudnason, V., Guénel, P., Guo, S., Hall, P., Hamann, U., Haring, R., Hartman, C.A., Heath, A.C., Hofman, A., Hooning, M.J. ,Hopper, J.L., Hu, F.B., Hunter, D.J., Karasik, D., Kiel, D.P., Knight, J.A., Kosma, V.M., Kutalik, Z., Lai, S., Lambrechts, D., Lindblom, A., Mägi, R., Magnusson, P.K., Mannermaa, A., Martin, N.G., Masson, G., McArdle, P.F., McArdle, W.L., Melbye, M., Michailidou, K., Mihailov, E., Milani, L., Milne, R.L., Nevanlinna, H., Neven, P., Nohr, E.A., Oldehinkel, A.J., Oostra, B.A., Palotie, A., Peacock, M., Pedersen, N.L., Peterlongo, P., Peto, J., Pharoah, P.D., Postma, D.S., Pouta, A., Pylkäs, K., Radice, P., Ring, S., Rivadeneira, F., Robino, A., Rose, L.M., Rudolph, A., Salomaa, V., Sanna, S., Schlessinger, D., Schmidt, M.K., Southey, M.C., Sovio, U., Stampfer, M.J., Stöckl, D., Storniolo, A.M., Timpson, N.J., Tyrer, J., Visser, J.A., Vollenweider, P., Völzke, H., Waeber, G., Waldenberger, M., Wallaschofski, H., Wang, Q., Willemsen, G., Winqvist, R., Wolffenbuttel, B.H., Wright, M.J.; Australian Ovarian Cancer Study; The GENICA Network; kConFab; The LifeLines Cohort Study; The InterAct Consortium; Early Growth Genetics (EGG) Consortium, Boomsma, D.I., Econs, M.J., Khaw, K.T., Loos, R.J., McCarthy, M.I., Montgomery, G.W., Rice, J.P., Streeten, E.A., Thorsteinsdottir, U., van Duijn, C.M., Alizadeh, B.Z., Bergmann, S., Boerwinkle, E., Boyd, H.A., Crisponi, L., Gasparini, P., Gieger, C., Harris, T.B., Ingelsson, E., Järvelin, M.R., Kraft, P., Lawlor, D., Metspalu, A., Pennell, C.E., Ridker, P.M., Snieder, H., Sørensen, T.I., Spector, T.D., Strachan, D.P., Uitterlinden, A.G., Wareham, N.J., Widen, E., Zygmunt, M., Murray, A., Easton, D.F., Stefansson, K., Murabito, J.M., and, Ong, KK. (2014).
Parent-of-origin specific allelic associations among 106 genomic loci for age at menarche.
Nature 514(7520):92-7. PMCID: PMC4185210 (pdf file)

*** Peterson, R.E., Maes, H.H., Lin, P., Kramer, J.R., Hesselbrock V.M., Bauer L.O., Nurnberger J.I., Edenberg, H.J., Dick, D.M., Webb, B.T. (2014).
On the association of common and rare genetic variation influencing body mass index: a combined SNP and CNV analysis.
BMC Genomics BMC Genomics 15(1):368. PMID: 24884913. PMCID: PMC4035084. (pdf file)

Rangaswamy, M. and Porjesz, B. (2014).
Understanding alcohol use disorders with neuroelectrophysiology.
In: Sullivan, E.V. and Pfefferbaum, A. (eds.), Handbook of Clinical Neurology, Volume 125 (3rd edition), Alcohol and the Nervous System.
Elsevier B.V., The Netherlands, ISBN-13: 978-0444626196
Handbook of Clinical Neurology 125C:383-414. PMID: 25307587.

*** Sadler, B., Haller, G., Agrawal, A., Culverhouse, R., Bucholz, K., Brooks, A., Tischfield, J., Johnson, E.O., Edenberg, H., Schuckit, M., Saccone, N., Bierut, L., and Goate, A. (2014).
Variants near CHRNB3-CHRNA6 are associated with DSM-5 cocaine use disorder: evidence for pleiotropy.
Scientific Reports 4:4497. PMID: 24675634. (pdf file)

Salvatore, J.E., Aliev, F., Bucholz, K., Agrawal, A., Hesselbrock, V., Hesselbrock, M., Bauer, L., Kuperman, S., Schuckit, M.A., Kramer, J., Edenberg, H.J., Foroud, T., and Dick, D.M. (2014).
Polygenic risk for externalizing disorders: Gene-by-development and gene-by-environment effects in adolescents and young adults.
Clinical Psychological Science xx(x):xxx-xxx. (pdf file)

Schuckit, M.A., Smith, T.L., Danko, G.P., Bucholz, K.K., Agrawal, A., Dick, D.M., Nurnberger, J.I., Kramer, J., Hesselbrock, M., Saunders, G., and Hesselbrock, V. (2014).
Predictors of subgroups based on maximum drinks per occasion over six years for 833 adolescents and young adults in COGA.
Journal of Studies on Alcohol and Drugs 75(1):24-34. PMID: 24411794. PMCID: PMC3893632. (pdf file)

*** van den Berg, S.M., de Moor, M.H., McGue, M., Pettersson, E., Terracciano, A., Verweij, K.J., Amin, N., Derringer, J., Esko, T., van Grootheest, G., Hansell, N.K., Huffman, J., Konte, B., Lahti, J., Luciano, M., Matteson, L.K., Viktorin, A., Wouda, J., Agrawal, A., Allik, J., Bierut, L., Broms, U., Campbell, H., Smith, G.D., Eriksson, J.G., Ferrucci, L., Franke, B., Fox, J.P., de Geus, E.J., Giegling, I., Gow, A.J., Grucza, R., Hartmann, A.M., Heath, A.C., Heikkilä, K., Iacono, W.G., Janzing, J., Jokela, M., Kiemeney, L., Lehtimäki, T., Madden, P.A., Magnusson, P.K., Northstone, K., Nutile, T., Ouwens, K.G., Palotie, A., Pattie, A., Pesonen, A.K., Polasek, O., Pulkkinen, L., Pulkki-Råback, L., Raitakari, O.T., Realo, A., Rose, R.J., Ruggiero, D., Seppälä, I., Slutske, W.S., Smyth, D.C., Sorice, R., Starr, J.M., Sutin, A.R., Tanaka, T., Verhagen, J., Vermeulen, S., Vuoksimaa, E., Widen, E., Willemsen, G., Wright, M.J., Zgaga, L., Rujescu, D., Metspalu, A., Wilson, J.F., Ciullo, M., Hayward, C., Rudan, I., Deary, I.J., Räikkönen, K., Arias Vasquez, A., Costa, P.T., Keltikangas-Järvinen, L., van Duijn, C.M., Penninx, B.W., Krueger, R.F., Evans, D.M., Kaprio, J., Pedersen, N.L., Martin, N.G., and Boomsma, D.I. (2014).
Harmonization of Neuroticism and Extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: an application of Item Response Theory.
Behavior Genetics 44(4):295-313. PMID: 24828478. PMCID: PMC4057636 (pdf file)

Wang, J.-C., Kapoor, M., and Goate, A.M. (2014).
Association of genes involved in calcium and potassium pathways with opioid dependence.
Biological Psychiatry 76(1):6-7 PMID: 24925890.

Comment on "Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways". [Biological Psychiatry. 2014]

Wetherill, L., Agrawal, A., Kapoor, M., Bertelsen, S., Bierut, L.J., Brooks, A., Dick, D., Hesselbrock, M., Hesselbrock ,V., Koller, D.L., Le, N., Nurnberger, J.I. Jr, Salvatore, J.E., Schuckit, M., Tischfield, J.A., Wang, J.C., Xuei, X., Edenberg, H.J., Porjesz, B., Bucholz, K., Goate, A.M., and Foroud, T. (2014).
Association of substance dependence phenotypes in the COGA sample.
Addiction Biololgy xx(x):xxx-xxx. PMID: 24832863. (pdf file)

Wetherill, L., Kapoor, M., Agrawal, A., Bucholz, K., Koller, D., E. Bertelsen, S.E., Nhug Le, N., Wang, J.-C., Almasy, L., Hesselbrock, V., Kramer, J., Nurnberger Jr, J.I., Schuckit, M., Tischfield, J.A., Xuei, X., Porjesz, B., Edenberg, H.J., M. Goate, A.M. and Foroud, T. (2014).
Family-based association analysis of alcohol dependence criteria and severity.
Alcoholism: Clinical and Experimental Research 38(2):354-366. PMID: 24015780. PMCID: PMC3946798. (pdf file)

Yan, J., Aliev, F., Webb, B.T., Kendler, K.S., Williamson, V.S., Edenberg, H.J., Agrawal, A., Kos, M.Z., Almasy, L., Nurnberger Jr, J.I., Schuckit, M.A., Kramer, J.R., Rice, J.P., Kuperman, S., Goate, A.M., Tischfield, J.A., Porjesz, B., and Dick, D.M. (2014).
Using genetic information from candidate gene and genome-wide association studies in risk prediction for alcohol dependence.
Addiction Biology 19(4):708-721. PMID: 23362995. PMCID: PMC3664249. (pdf file)


2013

*** Agrawal, A., Wetherill, L., Bucholz, K.K., Kramer, J., Kuperman, S., Lynskey, M.T., Nurnberger, J.I., Jr., Schuckit, M., Tischfield, J.A., Edenberg, H.J., Foroud, T., and Bierut, L.J. (2013).
Genetic influences on craving for alcohol.
Addictive Behaviors 38(2):1501-1508. PMID: 22481050.
(pdf file)

Chorlian, D.B., Rangaswamy, M., Manz, N., Wang, J.-C., Dick, D., Almasy, L., Bauer, L., Bucholz, K., Foroud, T., Hesselbrock, V., Kang, S., Kramer, J., Kuperman, S., Nurnberger Jr., J., Rice, J., Schuckit, M., Tischfield, J., Edenberg, H.J., Goate, A., Bierut, L., and Porjesz B. (2013).
Genetic and neurophysiological correlates of the age of onset of alcohol use disorders in adolescents and young adults.
Behavior Genetics 43(5):386-401. PMID: 23963516. (pdf file)

Culverhouse, R.C., Bowes, L., Breslau, N., Nurnberger, J.I. Jr, Burmeister, M., Fergusson, D.M., Munafò, M., Saccone, N.L., and Bierut, L.J. (2013)
Protocol for a collaborative meta-analysis of 5-HTTLPR, stress, and depression.
BMC Psychiatry 13(1):304. PMID: 24219410 (pdf file)

*** Davis, L.K., Yu, D., Keenan, C.L., Gamazon, E.R., Konkashbaev, A.I., Derks, E.M., Neale, B.M., Yang, J., Lee, S.H., Evans, P., Barr, C.L., Bellodi, L., Benarroch, F., Berrio, G.B., Bienvenu, O.J., Bloch, M.H., Blom, R.M., Bruun, R.D., Budman, C.L., Camarena, B., Campbell, D., Cappi, C., Cardona Silgado, J.C., Cath, D.C., Cavallini, M.C., Chavira, D.A., Chouinard, S., Conti, D.V., Cook, E.H., Coric, V., Cullen, B.A., Deforce, D., Delorme, R., Dion, Y., Edlund, C.K., Egberts, K., Falkai, P., Fernandez, T.V., Gallagher, P.J., Garrido, H., Geller, D., Girard, S.L., Grabe, H.J., Grados, M.A., Greenberg, B.D., Gross-Tsur, V., Haddad, S., Heiman, G.A., Hemmings, S.M., Hounie, A.G., Illmann, C., Jankovic, J., Jenike, M.A., Kennedy, J.L., King, R.A., Kremeyer, B., Kurlan, R., Lanzagorta, N., Leboyer, M., Leckman, J.F., Lennertz, L., Liu, C., Lochner, C., Lowe, T.L., Macciardi, F., McCracken, J.T., McGrath, L.M., Mesa Restrepo, S.C., Moessner, R., Morgan, J., Muller, H., Murphy, D.L., Naarden, A.L., Ochoa, W.C., Ophoff, R.A., Osiecki, L., Pakstis, A.J., Pato, M.T., Pato, C.N., Piacentini, J., Pittenger, C., Pollak, Y., Rauch, S.L., Renner, T.J., Reus, V.I., Richter, M.A., Riddle, M.A., Robertson, M.M., Romero, R., Rosàrio, M.C., Rosenberg, D., Rouleau, G.A., Ruhrmann, S., Ruiz-Linares, A., Sampaio, A.S., Samuels, J., Sandor, P., Sheppard, B., Singer, H.S., Smit, J.H., Stein, D.J., Strengman, E., Tischfield, J.A., Valencia Duarte, A.V., Vallada, H., Van Nieuwerburgh, F., Veenstra-Vanderweele, J., Walitza, S., Wang, Y., Wendland, J.R., Westenberg, H.G., Shugart, Y.Y., Miguel, E.C., McMahon, W., Wagner, M., Nicolini, H., Posthuma, D., Hanna, G.L., Heutink, P., Denys, D., Arnold, P.D., Oostra, B.A., Nestadt, G., Freimer, N.B., Pauls, D.L., Wray, N.R., Stewart, S.E., Mathews, C.A., Knowles, J.A., Cox, N.J., and Scharf, J.M. (2013).
Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture.
PLoS Genetics 9(10):e1003864. PMCID: PMC381203. (pdf file)

Derringer, J., Krueger, R.F., Dick, D.M., Agrawal, A., Bucholz, K.K., Foroud, T., Grucza, R.A., Hesselbrock, M.N., Hesselbrock, V., Kramer, J., Nurnberger, J.I. Jr, Schuckit, M., Bierut, L.J., Iacono, W.G., and McGue, M. (2013).
Measurement invariance of DSM-IV alcohol, marijuana and cocaine dependence between community-sampled and clinically overselected studies.
Addiction 108(10)1767-1776. PMID: 23651171. (pdf file)

Dick, D.M., Aliev, F., Latendresse, S., Porjesz, B., Schuckit, M., Rangaswamy, M., Hesselbrock, V., Edenberg, H., Nurnberger, J., Agrawal, A., Bierut, L., Wang, J., Bucholz, K., Kuperman, S., and Kramer, J. (2013).
How Phenotype and Developmental Stage Affect the Genes We Find: GABRA2 and Impulsivity.
Twin Research and Human Genetics 16(3):661-669. PMID: 23561058. (pdf file)

Edenberg, H.J. and Foroud, T. (2013).
Genetics and alcoholism.
Nature Reviews Gastroenterology & Hepatology 10:487-494. PMID: 23712313. (pdf file)

*** Fernández-Rhodes, L., Demerath, E.W., Cousminer, D.L., Tao, R., Dreyfus, J.G., Esko, T., Smith, A.V., Gudnason, V., Harris, T.B., Launer, L., McArdle, P.F., Yerges-Armstrong, L.M., Elks, C.E., Strachan, D.P., Kutalik, Z., Vollenweider, P., Feenstra, B., Boyd, H.A., Metspalu, A., Mihailov, E., Broer, L., Zillikens, M.C., Oostra, B., van Duijn, C.M., Lunetta, K.L., Perry, J.R., Murray, A., Koller, D.L., Lai, D., Corre, T., Toniolo, D., Albrecht, E., Stöckl, D., Grallert, H., Gieger, C., Hayward, C., Polasek, O., Rudan, I., Wilson, J.F., He, C., Kraft, P., Hu, F.B., Hunter, D.J., Hottenga, J.J., Willemsen, G., Boomsma, D.I., Byrne, E.M., Martin, N.G., Montgomery, G.W., Warrington, N.M., Pennell, C.E., Stolk, L., Visser, J.A., Hofman, A., Uitterlinden, A.G., Rivadeneira, F., Lin, P., Fisher, S.L., Bierut, L.J., Crisponi, L., Porcu, E., Mangino, M., Zhai, G., Spector, T.D., Buring, J.E., Rose, L.M., Ridker, P.M., Poole, C., Hirschhorn, J.N., Murabito, J.M., Chasman, D.I., Widen, E., North, K.E., Ong, K.K., and Franceschini, N. (2013).
Association of adiposity genetic variants with menarche timing in 92,105 women of European descent.
American Journal of Epidemiology 178(3):451-460. PMID: 23558354. (pdf file)

Hashimoto, E., Riederer, P.F., Hesselbrock, V.M., Hesselbrock, M.N., Mann, K., Ukai, W., Sohma, H., Thibaut, F., Schuckit, M.A., and Saito, T. (2013)
Consensus paper of the WFSBP task force on biological markers: Biological markers for alcoholism.
The World Journal of Biological Psychiatry 14(8):549-564. PMID: 24236956 (pdf file)

Hesselbrock, M.N., Hesselbrock, V.M., and Chartier, K.G. (2013).
Genetics of alcohol dependence and social work research: do they mix?
Social Work in Public Health 28(3-4):178-193. PMID: 23731413. (pdf file)

Johnson, E.O., Hancock, D.B., Levy, J.L., Gaddis, N.C., Saccone, N.L., Bierut, L.J., and Page, G.P. (2013)
Imputation across genotyping arrays for genome-wide association studies: assessment of bias and a correction strategy.
Human Genetics 132(5):509-522. PMID: 23334152. (pdf file)

Kapoor, M., Wang, J.C., Wetherill, L., Le, N., Bertelsen, S., Hinrichs, A.L., Budde, J., Agrawal, A., Bucholz, K., Dick, D., Harari, O., Hesselbrock, V., Kramer, J., Nurnberger, J.I. Jr, Rice, J., Saccone, N., Schuckit, M., Tischfield, J., Porjesz, B., Edenberg, H.J., Bierut, L., Foroud, T., and Goate, A. (2013)
Meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.
Human Genetics 132(10):1141-1151. PMID: 23743675 (pdf file)

*** Kos, M.Z., Yan, J., Dick, D.M., Agrawal, A., Bucholz, K.K., Rice, J.P., Johnson, E.O., Schuckit, M., Kuperman, S., Kramer, J., Goate, A.M., Tischfield, J.A., Foroud, T., Nurnberger, J.I., Jr., Hesselbrock, V., Porjesz, B., Bierut, L.J., Edenberg, H.J., and Almasy, L. (2013).
Common biological networks underlie genetic risk for alcoholism in African- and European-American populations.
Genes, Brain and Behavior 12(5):532-542. PMID: 23607416. (pdf-file)

Kuperman, S., Chan, G., Kramer, J.R., Wetherill, L., Bucholz, K.K., Dick, D., Hesselbrock, V., Porjesz, B., Rangaswamy, M., and Schuckit, M. (2013).
A model to determine the likely age of an adolescent's first drink of alcohol.
Pediatrics 131(2):242-248. PMID: 23296431. (pdf file)

McClintick, J.N., Xuei, X., Tischfield, J.A., Goate, A., Foroud, T., Wetherill, L., Ehringer, M.A., and Edenberg, H.J. (2013)
Stress-response pathways are altered in the hippocampus of chronic alcoholics.
Alcohol 47(7):505-515 PMID: 23981442. PMCID: PMC3836826. (pdf file)

Perry, B.L., Pescosolido, B.A., Bucholz, K., Edenberg, H., Kramer, J., Kuperman, S., Schuckit, M.A., and Nurnberger, J.I. Jr. (2013).
Gender-Specific Gene-Environment Interaction in Alcohol Dependence: The Impact of Daily Life Events and GABRA2.
Behavior Genetics 43(5) 402-414. PMID: 23974430. (pdf file)

*** Scharf, J.M., Yu, D., Mathews, C.A., Neale, B.M., Stewart, S.E., Fagerness, J.A., Evans, P., Gamazon, E., Edlund, C.K., Service, S.K., Tikhomirov, A., Osiecki, L., Illmann, C., Pluzhnikov, A., Konkashbaev, A., Davis, L.K., Han, B., Crane, J., Moorjani, P., Crenshaw, A.T., Parkin, M.A., Reus, V.I., Lowe, T.L., Rangel-Lugo, M., Chouinard, S., Dion, Y., Girard, S., Cath, D.C., Smit, J.H., King, R.A., Fernandez, T.V., Leckman, J.F., Kidd, K.K., Kidd, J.R., Pakstis, A.J., State, M.W., Herrera, L.D., Romero, R., Fournier, E., Sandor, P., Barr, C.L., Phan, N., Gross-Tsur, V., Benarroch, F., Pollak, Y., Budman, C.L., Bruun, R.D., Erenberg, G., Naarden, A.L., Lee, P.C., Weiss, N., Kremeyer, B., Berrío, G.B., Campbell, D.D., Cardona Silgado, J.C., Ochoa, W.C., Mesa Restrepo, S.C., Muller, H., Valencia Duarte, A.V., Lyon, G.J., Leppert, M., Morgan, J., Weiss, R., Grados, M.A., Anderson, K., Davarya, S., Singer, H., Walkup, J., Jankovic, J., Tischfield, J.A., Heiman, G.A., Gilbert, D.L., Hoekstra, P.J., Robertson, M.M., Kurlan, R., Liu, C., Gibbs, J.R., Singleton, A.; North American Brain Expression Consortium, Hardy, J.; UK Human Brain Expression Database, Strengman, E., Ophoff, R.A., Wagner, M., Moessner, R., Mirel, D.B., Posthuma, D., Sabatti, C., Eskin, E., Conti, D.V., Knowles, J.A., Ruiz-Linares, A., Rouleau, G.A., Purcell, S., Heutink, P., Oostra, B.A., McMahon, W.M., Freimer, N.B., Cox, N.J., and Pauls, D.L. (2013).
Genome-wide association study of Tourette’s syndrome.
Molecular Psychiatry 18(6):721-728. PMID: 22889924. PMCID: PMC3605224. (pdf file)

Wang, J.-C., Foroud, T., Hinrichs, A.L., Le, N. X. H., Bertelsen, S., Budde, J. P., Harari, O., Koller, D.L., Wetherill, L., Agrawal, A., Almasy, L., Brooks, A. I., Bucholz, K., Dick, K., Hesselbrock, V., Johnson, E.O., Kang, S., Kapoor, M., Kramer, J., Kuperman, S., Madden, P. A. F., Manz, N., Martin, N. G., McClintick, J. N., Montgomery, G. W., Nurnberger, J.I., Jr., Rangaswamy, M., Rice, J., Schuckit, M., Tischfield, J. A., Whitfield, J. B., Xuei, X., Porjesz, B., Heath, A. C., Edenberg, H. .J., Bierut, L.J., and Goate, A. M. (2013).
A genome wide association study of alcohol dependence symptom counts in extended pedigrees identifies C15orf53.
Molecular Psychiatry 18(11):1218-1224. PMID: 23089632. (pdf file)

Wang, J.-C., Spiegel, N., Bertelsen, S., Le, N., McKenna, N., Budde, J.P., Harari, O., Kapoor, M., Brooks, A., Hancock, D., Tischfield, J., Foroud, T., Bierut, L.J., Steinbach, J.H., Edenberg, H.J., Traynor, B.J., and Goate, A.M. (2013)
Cis-regulatory variants affect CHRNA5 mRNA expression in populations of African andEuropean ancestry.
PLoS One 8(11):e80204. PMID: 24303001. (pdf file)

Zhang ,Z., Wang, J.-C., Howells, W., Lin, P., Agrawal, A., Edenberg, H.J., Tischfield, J.A., Schuckit, M.A., Bierut, L.J., Goate, A., and Rice, J.P. (2013).
Dosage Transmission Disequilibrium Test (dTDT) for Linkage and Association Detection.
PLoS One 8(5): e63526. PMID: 23691058. (pdf file)


2012

Agrawal, A. and Bierut, L.J. (2012).
Identifying genetic variation for alcohol dependence.
Alcohol Research and Health 34(3):274-281.
(pdf file)

** Agrawal, A., Freedman, N.D., Cheng, Y.C., Lin, P., Shaffer, J.R., Sun, Q., Taylor, K., Yaspan, B., Cole, J.W., Cornelis, M.C., Desensi, R.S., Fitzpatrick, A., Heiss, G., Kang, J.H., O'Connell, J., Bennett, S., Bookman, E., Bucholz, K.K., Caporaso, N., Crout, R., Dick, D.M., Edenberg, H.J., Goate, A., Hesselbrock, V., Kittner, S., Kramer, J., Nurnberger, J.I. Jr, Qi, L., Rice, J.P., Schuckit, M., van Dam, R.M., Boerwinkle, E., Hu, F., Levy, S., Marazita, M., Mitchell, B.D., Pasquale, L.R., and Bierut, L.J.; for the GENEVA Consortium (2012).
Measuring alcohol consumption for genetic meta-analyses of alcohol intake: Opportunities and challenges.
American Journal of Clinical Nutrition 95(3):539-547. PMCID: PMC3278237, PMID: 22301922. (pdf file)


Bierut, L.J., Goate, A.M., Breslau, N., Johnson, E.O., Bertelsen, S., Fox, L., Agrawal, A., Bucholz, K.K., Grucza, R., Hesselbrock, V., Kramer, J., Kuperman, S., Nurnberger, J., Porjesz, B., Saccone, N.L., Schuckit, M., Tischfield, J., Wang, J.C., Foroud, T., Rice, J.P., and Edenberg, H.J. (2012).
ADH1B is associated with alcohol dependence and alcohol consumption in populations of European and African ancestry.
Molecular Psychiatry 17(4):445-450. PMCID: PMC3252425. (pdf file)

Chen, A.C., Rangaswamy, M., and Porjesz, B. (2012).
Endophenotyes in psychiatric genetics.
In: Nurnberger, J.I., Jr. and Berretini, W.H. (eds.), Principles of Psychiatric Genetics.

Cambridge University Press, pp 347-362. (pdf file)

*** Chen, L.S., Baker, T.B., Piper, M.E., Breslau, N., Cannon, D.S., Doheny, K.F., Gogarten, S.M., Johnson, E.O., Saccone, N.L., Wang, J.C., Weiss, R.B., Goate, A.M., and Bierut, L.J. (2012)
Interplay of genetic risk factors (CHRNA5-CHRNA3-CHRNB4) and cessation treatments in smoking cessation success.
American Journal of Psychiatry 169(7):735-742. PMID: 22648373 (pdf file)

*** Chen, L.S., Saccone, N.L., Culverhouse, R.C., Bracci, P.M., Chen, C.H., Dueker, N., Han, Y., Huang, H., Jin, G., Kohno, T., Ma, J.Z., Przybeck, T.R., Sanders, A.R., Smith, J.A., Sung, Y.J., Wenzlaff, A.S., Wu, C., Yoon, D., Chen, Y.T., Cheng, Y.C., Cho, Y.S., David, S.P., Duan, J., Eaton, C.B., Furberg, H., Goate, A.M., Gu, D., Hansen, H.M., Hartz, S., Hu, Z., Kim, Y.J., Kittner, S.J., Levinson, D.F., Mosley, T.H., Payne, T.J., Rao, D.C., Rice, J.P., Rice, T.K., Schwantes-An, T.H., Shete, S.S., Shi, J., Spitz, M.R., Sun, Y.V., Tsai, F.J., Wang, J.C., Wrensch, M.R., Xian, H., Gejman, P.V., He, J., Hunt, S.C., Kardia, S.L., Li, M.D., Lin, D., Mitchell, B.D., Park, T., Schwartz, A.G., Shen, H., Wiencke, J.K., Wu, J.Y., Yokota, J., Amos, C.I., and Bierut, L.J. (2012)
Smoking and genetic risk variation across populations of European, Asian, and African-American ancestry - a meta-analysis of chromosome 15q25.
Genetic Epidemiology 2012; 36(4):340-351. PMCID: PMC3387741. (pdf file)


*** de Moor, M.H., Costa, P.T., Terracciano, A., Krueger, R.F., de Geus, E.J., Toshiko, T., Penninx, B.W., Esko, T., Madden, P.A., Derringer, J., Amin, N., Willemsen, G., Hottenga, J.J., Distel, M.A., Uda, M., Sanna, S., Spinhoven, P., Hartman, C.A., Sullivan, P., Realo, A., Allik, J., Heath, A.C., Pergadia, M.L., Agrawal, A., Lin, P., Grucza, R., Nutile, T., Ciullo, M., Rujescu, D., Giegling, I., Konte, B., Widen, E., Cousminer, D.L., Eriksson, J.G., Palotie, A., Peltonen, L., Luciano, M., Tenesa, A., Davies, G., Lopez, L.M., Hansell, N.K., Medland, S.E., Ferrucci, L., Schlessinger, D., Montgomery, G.W., Wright, M.J., Aulchenko, Y.S., Janssens, A.C., Oostra, B.A., Metspalu, A., Abecasis, G.R., Deary, I.J., Räikkönen, K., Bierut, L.J., Martin, N.G., van Duijn, C.M., Boomsma, D.I. (2012).

Meta-analysis of genome-wide association studies for personality.
Molecular Psychiatry 17(3):337-349, PMID: 21173776. (pdf file)


*** Derringer, J., Krueger, R.F., Dick, D.M., Aliev, F., Grucza, R.A., Saccone, S., Agrawal, A., Edenberg, H.J., Goate, A.M., Hesselbrock, V.M., Kramer, J.R., Lin, P., Neuman, R.J., Nurnberger, J.I., Jr., Rice, J.P., Tischfield, J.A.; GENEVA consortium, and Bierut, L.J. (2012).
The aggregate effect of dopamine genes on dependence symptoms among cocaine users: Cross-validation of a candidate system scoring approach.
Behavior Genetics 42(4):626-35. PMCID: PMC3416038. (pdf file)

Edenberg, H.J. (2012).
Alcoholism.
In: Nurnberger, J.I, Jr. and Berretini, W.H. (eds.), Principles of Psychiatric Genetics.

Cambridge University Press, pp 279-286. (pdf file)


Edenberg, H.J. (2012).
Genes contributing to the development of alcoholism: An overview.
Alcohol Research 34(3):336-338. PMID: 23134049. (pdf file)


Edwards, A.C., Aliev, F., Bierut, L.J., Bucholz, K.K., Edenberg, H., Hesselbrock, V., Kramer ,J., Kuperman, S., Nurnberger, J.I. Jr, Schuckit, M.A., Porjesz, B., and Dick, D.M. (2012).
Genome-wide association study on comorbid depressive syndrome and alcohol dependence.
Psychiatric Genetics 22(1):31-41. PMCID: PMC3241912. (pdf file)


Harari, O., Wang, J.C., Bucholz, K., Edenberg, H.J., Heath, A., Martin, N.G., Pergadia, M.L., Montgomery, G., Schrage, A., Bierut, L.J., Madden, P.F., and Goate, A.M. (2012).
Pathway analysis of smoking quantity in multiple GWAS identifies cholinergic and sensory pathways.
PLoS One 7(12):e50913. (pdf file)

*** Hartz, S., Short, S., Saccone, N., Culverhouse, R., Chen, L., Schwantes-An, T., Coon, H., Han, Y., Stephens, S., Sun, J., Chen, X., Ducci, F., Dueker, N., Franceschini, N., Frank, J., Geller, F., Guðbjartsson, D., Hansel, N., Jiang, C., Keskitalo-Vuokko, K., Liu, J., Lyytikäinen, L., Michel, M., Rawal, R., Rosenberger, A., Scheet, P., Shaffer, J., Teumer, A., Thompson, J., Vink, J., Vogelzangs, N., Wenzlaff, A., Wheeler, W., Xiangjun, X., Yang, B., Aggen, S., Balmforth, A., Baumeister, S., Beaty, T., Bennett, S., Bergen, A., Boyd, H., Broms, U., Campbell, H., Chatterjee, N., Chen, J., Cheng, Y., Cichon, S., Couper, D., Cucca, F., Dick, D., Foroud, T., Furberg, H., Giegling, I., Gu, F., Hall, A., Hällfors, J., Han, S., Hartmann, A., Hayward, C., Heikkilä, K., Hewitt, J., Hottenga, J., Jensen, M., Jousilahti, P., Kaakinen, M., Kittner, S., Konte, B., Korhonen, T., Landi, M., Laatikainen, T., Leppert, M., Levy, S., Mathias, R., McNeil, D., Medland, S., Montgomery, G., Muley, T., Murray, T., Nauck, M., North, K., Pergadia, M., Polasek, O., Ramos, E., Ripatti, S., Risch, A., Ruczinski, I., Rudan, I., Salomaa, V., Schlessinger, D., Styrkársdóttir, U., Terracciano, A., Uda, M., Willemsen, G., Wu, X., Abecasis, G., Barnes, K., Bickeböller, H., Boerwinkle, E., Boomsma, D., Caporaso, N., Duan, J., Edenberg, H., Francks, C., Gejman, P., Gelernter, J., Grabe, H., Hops, H., Jarvelin, M., Jorma, V., Kähönen, M., Kendler, K., Lehtimäki, T., Levinson, D., Marazita, M., Marchini, J., Melbye, M., Mitchell, B., Murray, J., Nöthen, M., Penninx, B., Raitakari, O., Rietschel, M., Rujescu, D., Samani, N., Sanders, A., Schwartz, A., Shete, S., Shi, J., Spitz, M., Stefansson, K., Swan, G., Thorgeirsson, T., Völzke, H., Wei, Q., Wichmann, H., Amos, C., Breslau, N., Cannon, D., Ehringer, M., Grucza, R., Hatsukami, D., Heath, A., Johnson, E., Kaprio, J., Madden, P., Martin, N., Stevens, V., Stitzel, J., Weiss, R., Kraft, P., and Bierut, L. (2012).
Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers.
Archives of General Psychiatry
69(8):854-860, PMID: 22868939. (pdf file) (supplement)

Hurley, T.D. and Edenberg, H.J. (2012).
Genes encoding enzymes involved in ethanol metabolism.
Alcohol Research 34(3):339-344. PMID: 23134050. (pdf file)

Kamarajan, C., Rangaswamy, M., Manz, N., Chorlian, D.B., Pandey, A.K., Roopesh, B.N., and Porjesz, B. (2012).
Topography, power and current source density of theta oscillations during reward processing as markers for alcohol dependence.
Human Brain Mapping 33(5):1019-1039. PMID: 21520344. (pdf file)


Kang, S.J., Rangaswamy, M., Manz, N., Wang, J.-C., Wetherill, L., Hinrichs, T., Almasy, L., Brooks, A., Chorlian, D.B., Dick, D., Hesselbrock, V., Kramer, J., Kuperman, S., Nurnberger Jr, J., Rice, J., Schuckit, M., Tischfield, J., Bierut, L.J., Edenberg, H.J., Goate, A., Foroud, T., and Porjesz, B. (2012).
Family-based genome-wide association study of frontal theta oscillations identifies potassium channel gene KCNJ6.
Genes, Brain and Behavior 11(6):712-719. PMID: 22554406. (pdf file and supplement)

Kapoor, M., Wang, J.C., Bertelsen, S., Bucholz, K., Budde, J.P., Hinrichs, A., Agrawal, A., Brooks, A., Chorlian, D.B., Dick, D., Hesselbrock, V., Foroud, T., Kramer, J., Kuperman, J., Manz, N., Nurnberger, J., Jr., Porjesz, B., Rice, J.P., Tischfield, J., Xuei, X., Schuckit, M., Edenberg, H.J., Bierut, L.J., and Goate, A. (2012).
Variants located upstream of CHRNB4 on chromosome 15q25.1 are associated with age at onset of daily smoking and habitual smoking.
PLoS ONE 7(3):e33513. PMCID: PMC3306405. (pdf file)

*** Laurie, C.C., Laurie, C.A., Rice, K., Doheny, K.F., Zelnick, L.R., McHugh, C.P., Ling, H., Hetrick, K.N., Pugh, E.W., Amos, C., Wei, Q., Wang, L.E., Lee, J.E., Barnes, K.C., Hansel, N.N., Mathias, R., Daley, D., Beaty, T.H., Scott, A.F., Ruczinski, I., Scharpf, R.B., Bierut, L.J., Hartz, S.M., Landi, M.T., Freedman, N.D., Goldin, L.R., Ginsburg, D., Li, J., Desch, K.C., Strom, S.S., Blot, W.J., Signorello, L.B., Ingles, S.A., Chanock, S.J., Berndt, S.I., Le Marchand, L., Henderson, B.E., Monroe, K.R., Heit, J.A., de Andrade, M., Armasu, S.M., Regnier, C., Lowe, W.L., Hayes, M.G., Marazita, M.L., Feingold, E., Murray, J.C., Melbye, M., Feenstra, B., Kang, J.H., Wiggs, J.L., Jarvik, G.P., McDavid, A.N., Seshan, V.E., Mirel, D.B., Crenshaw, A., Sharopova, N., Wise, A., Shen, J., Crosslin, D.R., Levine, D.M., Zheng, X., Udren, J.I., Bennett, S., Nelson, S.C., Gogarten, S.M., Conomos, M.P., Heagerty, P., Manolio, T., Pasquale, L.R., Haiman, C.A., Caporaso, N., and Weir, B.S. (2012).
Detectable clonal mosaicism from birth to old age and its relationship to cancer.
Nature Genetics 44(6):642-50. PMCID: PMC3366033 (pdf file)

*** Lin, P., Hartz, S.M. Wang, J.-W. Agrawal, A., Zhang, T.-X. McKenna, N., Bucholz, K., Brooks, A.I., Tischfield, J.A., Edenberg, H.J., Hesselbrock, V.M., Kramer, J.R., Kuperman, S., Schuckit, M.A., Goate, A.M., Bierut, L.J., Rice, J.P., COGA Collaborators, COGEND Collaborators, and GENEVA (2012).
Copy number variations in 6q14.1 and 5q13.2 are associated with alcohol dependence.
Alcoholism: Clinical and Experimental Research 36(9):1512-1518. PMCID: PMC3436997. (pdf file)


*** Luciano, M., Lopez, L.M., de Moor, M.H., Harris, S.E., Davies, G., Nutile, T., Krueger, R.F., Esko, T., Schlessinger, D., Toshiko, T., Derringer, J.L., Realo, A., Hansell, N.K., Pergadia, M.L., Pesonen, A.K., Sanna, S., Terracciano, A., Madden, P.A., Penninx, B., Spinhoven, P., Hartman, C.A., Oostra, B.A., Janssens, A.C., Eriksson, J.G., Starr, J.M., Cannas, A., Ferrucci, L., Metspalu, A., Wright, M.J., Heath, A.C., van Duijn, C.M., Bierut, L.J., Raikkonen, K., Martin, N.G., Ciullo, M., Rujescu, D., Boomsma, D.I., and Deary, I.J. (2012).
Longevity candidate genes and their association with personality traits in the elderly.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 159B(2):192-200. PMID: 22213687. (pdf file)

*** Olfson, E. and Bierut, L.J. (2012).
Convergence of genome-wide association and candidate gene studies for alcoholism.

Alcoholism: Clinical and Experimental Research 36(12):2086-2094. PMCID: PMC352108 (pdf file)

Pandey, A.K., Kamarajan, C., Rangaswamy, M., and Porjesz, B. (2012).
Event-related oscillations in alcoholism research: A review.
Journal of Addiction Research & Therapy S7:1-13. PMID: 24273686. (pdf file)

Pandey, A.K., Kamarajan, C., Tang, Y., Chorlian, D.B., Roopesh, B.N.,  Manz, N., Stimus, A., Rangaswamy, M.,  and Porjesz, B. (2012).

Neurocognitive deficits in male alcoholics: An ERP/sLORETA analysis of the N2 component in an equal probability Go/NoGo task .

Biological Psychology 89(1):170-182. PMID: 22024409. PMCID: PMC3245806. (pdf file)

*** Rice, J.P., Hartz, S., Agrawal, A., Almasy, L., Bennett, S., Breslau, N., Bucholz, K.K., Doheny, K.F., Edenberg, H.J., Goate, A.M., Hesselbrock, V., Howells, W.B., Johnson, E.O., Kramer, J., Krueger, R.F., Kuperman, S., Laurie, C., Manolio, T.A., Neuman, R.J., Nurnberger, J.I., Jr., Porjesz, B., Pugh, E., Ramos, E.M., Saccone, N., Saccone, S., Schuckit, M., and Bierut, L.J., as part of the GENEVA Consortium (2012).

CHRNB3 is more strongly associated with Fagerström Test for Cigarette Dependence-based nicotine dependence than cigarettes per day: Phenotype definition changes genome-wide association studies results.

Addiction 107(11):2019-2028. PMID: 22524403. (pdf file)

Schuckit, M.A., Smith, T.L., Trim, R.S., Kuperman, S., Kramer, J., Hesselbrock, V., Bucholz, K.K., Nurnberger, J.I., Jr., Hesselbrock, M., and Saunders, G. (2012).

Sex differences in how a low sensitivity to alcohol relates to later heavy drinking.

Drug and Alcohol Review 31(7):871-880. PMID: 22708705. (pdf file)

*** Spitz, M.R., Amos, C.I., Bierut, L.J., and Caporaso, N.E. (2012).
Cotinine conundrum – a step forward but questions remain. (Editorial).
Journal of the National Cancer Institute 104(10):720-2. PMCID: PMC3352835. (pdf file)

Wang, J.-C., Kapoor, M., and Goate, A.M. (2012).
The genetics of substance dependence.
Annual Review of Genomics and Human Genetics 13:241-261. PMCID: PMC3474605 (pdf file)

Zhao, Z., Guo, A.-Y., van den Oord, E.J.C.G, Aliev, F., Jia, P., Edenberg, H.J., Riley, B.P., Dick, D.M., Bettinger, J.C., Davies, A.G., Grotewiel, M.S., Schuckit, M.A., Agrawal, A., Kramer, J., Nurnberger, J.I., Kendler, K.S., Webb, B.T., and Miles, M.F. (2012).
Multi-species data integration and gene ranking enrich significant results in an alcoholism genome-wide association study.
BMC Genomics 13(Suppl 8):S16. (pdf file)

2011

Agrawal, A., Freedman, N.D., and Bierut, L.J. (2011).
Genome-wide association studies of alcohol intake - a promising cocktail?
American Journal of  Clinical Nutrition
93(4):681-683. PMCID: PMC3057543. (pdf file)

*** Agrawal, A., Lynskey, M.T., Hinrichs, A., Grucza, R., Saccone, S.F., Krueger, R., Neuman, R., Howells, W., Fisher, S., Fox, L., Cloninger, R., Dick, D.M., Doheny, K.F., Edenberg, H.J., Goate, A.M., Hesselbrock, V., Johnson, E., Kramer, J., Kuperman, S., Nurnberger, J.I., Jr., Pugh, E., Schuckit, M., Tischfield, J., The GENEVA Consortium, Rice, J.P., Bucholz,, K.K., and Bierut, L.J. (2011)
A genome-wide association study of DSM-IV cannabis dependence.
Addiction Biology
16(3):514-518. PMCID: PMC3117436.

*** Bennett, S.N., Caporaso, N., Fitzpatrick, A.L., Agrawal, A., Barnes, K., Boyd, H.A., Cornelis, M.C., Hansel, N.N., Heiss, G., Heit, J.A., Kang, J.H., Kittner, S.J., Kraft, P., Lowe, W., Marazita, M.L., Monroe, K.R., Pasquale, L.R., Ramos, E.M., van Dam, R.M., Udren, J., and Williams, K.; GENEVA Consortium (2011).
Phenotype harmonization and cross-study collaboration in GWAS consortia: The GENEVA experience.
Genetic Epidemiology 35(3):159-173. PMCID: PMC3055921.

Bierut, L.J. (2011).
Genetic vulnerability and susceptibility to substance dependence.
NEURON 69(4):618-627. PMCID: PMC3095110. (pdf file)

*** Derringer, J., Krueger, R.F., Manz, N., Porjesz, B., Almasy, L., Bookman, E., Edenberg, H.J., Kramer, J.R., Tischfield, J.A., and Bierut, L.J. (2011).
Nonreplication of an association of SGIP1 SNPs with alcohol dependence and resting theta EEG power.
Psychiatric Genetics 21(5):265-266. PMCID: PMC3139721. (pdf file and supplement)

Dick, D.M. (2011).
Gene-environment interaction in psychological traits and disorders.
Annual review of clinical psychology 7:383-409. PMID: 21219196. (pdf file)

*** Dick, D.M., Aliev, F., Krueger, R.F., Edwards, A., Agrawal, A., Lynskey, M., Lin, P., Schuckit, M., Hesselbrock, V., Nurnberger, J. Jr, Almasy, L., Porjesz, B., Edenberg, H.J., Bucholz, K., Kramer, J., Kuperman, S., and Bierut, L. as part of the SAGE and GENEVA Consortia (2011).
Genome-wide association study of conduct disorder symptomatology.
Molecular Psychiatry 16(8):800-808. PMID: 20585324, NIHMSID: 264833. (pdf file)

Dick, D.M., Meyers, J.L., Latendresse, S.J., Creemers, H.E., Lansford, J.E., Pettit, G.S., Bates, J.E., Dodge, K.A., Budde, J., Goate, A., Buitelaar, J.K., Ormel, J., Verhulst, F.C., and Huizink, A.C. (2011).
CHRM2, parental monitoring, and adolescent externalizing behavior: evidence for gene-environment interaction.
Psychological Sciences
22(4):481-489. PMID: 21441226.

Edenberg, H. (2011).
Common and rare variants in alcohol dependence.
Biological Psychiatry 70(6):498-499. PMID: 21864733. (pdf file)

*** Hartz SM, Johnson EO, Saccone NL, Hatsukami D, Breslau N, Bierut LJ (2011).
Inclusion of African Americans in genetic studies: what is the barrier?
American Journal of Epidemiology 174(3):336-44. PMCID: PMC3202157. (pdf file)


Hinrichs, A., Culverhouse, R., and Suarez, B. (2011).
Linkage analysis merging replicate phenotypes: An application to three quantitative phenotypes in two African samples.
BMC Proceedings
5(Suppl 9):S81. (pdf file)

Johnson C, Drgon T, Walther D, Uhl GR (2011).
Genomic regions identified by overlapping clusters of nominally-positive SNPs from genome-wide studies of alcohol and illegal substance dependence.
PLoS ONE 6(7):e19210. PMCID: PMC3144872. (pdf file)

Latendresse, S.J., Bates, J.E., Goodnight, J.A., Lansford, J.E., Budde, J.P., Goate, A., Dodge, K.A., Pettit, G.S., and Dick, D.M. (2011).
Differential susceptibility to adolescent externalizing trajectories: Examining the interplay between CHRM2 and peer group antisocial behavior.
Child development 82(6):1797-814. PMCID: PMC3218245.

*** Lin, P., Hartz, S.M., Wang, J.C., Krueger, R.F., Foroud, T.M., Edenberg, H.J., Nurnberger, J.I., Jr., Brooks, A.I., Tischfield, J.A., Almasy, L., Webb, B.T., Hesselbrock, V.M., Porjesz, B., Goate, A.M., Bierut, L.J., Rice, J.P.,COGA Collaborators, COGEND Collaborators, and GENEVA (2011).
Copy number variation accuracy in genome-wide association studies.
Human Heredity 71(3):141-147. PMID: 21778733 (pdf file)

Maher, B.S., Vladimirov, V.I., Latendresse, S.J., Thiselton, D.L., McNamee, R., Kang, M., Bigdeli, T.B., Chen, X., Riley, B.P., Hettema, J.M., Chilcoat, H., Heidbreder, C., Muglia, P., Murrelle, E.L., Dick, D.M., Aliev, F., Agrawal, A., Edenberg, H.J., Kramer, J., Nurnberger, J., Tischfield, J.A,. Devlin, B., Ferrell, R.E., Kirillova, G.P., Tarter, R.E., Kendler, K.S., and Vanyukov, M.M. (2011).
The AVPR1A gene and substance use disorders: association, replication, and functional evidence.
Biological Psychiatry 70(6):519-527. PMID: 21514569. (pdf file)

McCutcheon, V.V., Agrawal, A., Heath, A.C., Edenberg, H.J., Hesselbrock, V.M., Schuckit, M.A., Kramer, J.R., and Bucholz, K.K. (2011).
Functioning of alcohol use disorder criteria among men and women with arrests for driving under the influence of alcohol.
Alcoholism: Clinical and Experimental Research
35(11):1985-1993. PMCID: PMC3166544. (pdf file)

*** Middeldorp, C.M., de Moor, M.H.M., McGrath, L.M., Gordon, S.D., Blackwood, D.H., Costa, P.T., Terracciano, A.., Krueger, R.F., de Geus, E.J.C., Nyholt, D.R., Tanaka, T., Esko, T., Madden, P.A.F., Derringer, J., Amin, N., Willemsen, G., Hottenga, J.-J., Distel, M.A., Uda, M., Sanna, S., Spinhoven, P., Hartman, C.A., Ripke, S., Sullivan, P.F., Realo, A., Allik, J., Heath, A.C., Pergadia, M.L., Agrawal, A., Lin, P., Grucza, R.A., Widen, E., Cousminer, D.L., Eriksson, J.G., Palotie, A., Barnett, J.H., Lee, P.H., Luciano, M., Tenesa, A., Davies, G., Lopez, L.M., Hansell, N.K., Medland, S.E., Ferrucci, L., Schlessinger, D., Montgomery, G.W., Wright, M.J., Aulchenko, Y.S., Janssens, A.C.J.W., Oostra, B.A., Metspalu, A., Abecasis, G.R., Deary, J., Räikkönen, K., Bierut, L.J., Martin, N.G., Wray, N.R., van Duijn, C.M., Smoller, J.W, Penninx, B.W.J.H, and Boomsma D.I. (2012).
The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data.
Translational Psychiatry
1:e50. PMCID: PMC3309491. (pdf file and supplement figures 1A, 1B, 1C and Legend)

Schuckit, M.A., Smith, T.L., Trim, R.S., Allen, R.C., Fukukura, T., Knight, E.E., Cesario, E.M., and Kreikebaum, S.A. (2011).
A prospective evaluation of how a low level of response to alcohol predicts later heavy drinking and alcohol problems.
American Journal of Drug Alcohol Abuse
37(6):479-86. PMID: 21797810.

Schumann, G., Coin, L.J., Lourdusamy, A., Charoen, P., Berger, K.H., Stacey, D., Desrivières, S., Aliev, F.A., Khan, A.A., Amin, N., Aulchenko, Y.S., Bakalkin, G., Bakker, S.J., Balkau, B., Beulens, J.W., Bilbao, A., de Boer, R.A., Beury, D., Bots, M.L., Breetvelt, E.J., Cauchi, S., Cavalcanti-Proença, C., Chambers, J.C., Clarke, T.K., Dahmen, N., de Geus, E.J., Dick, D., Ducci, F., Easton, A., Edenberg, H.J., Esk, T., Fernández-Medarde, A., Foroud, T., Freimer, N.B., Girault, J.A., Grobbee, D.E., Guarrera, S., Gudbjartsson, D.F., Hartikainen, A.L., Heath, A.C., Hesselbrock, V., Hofman, A., Hottenga, J.J., Isohanni, M.K., Kaprio, J., Khaw, K.T., Kuehnel, B., Laitinen, J., Lobbens, S., Luan, J., Mangino, M., Maroteaux, M., Matullo, G., McCarthy, M.I., Mueller, C., Navis, G., Numans, M.E., Núñez, A., Nyholt, D.R., Onland-Moret, C.N., Oostra, B.A., O'Reilly, P.F., Palkovits, M., Penninx, B.W., Polidoro, S., Pouta, A., Prokopenko, I., Ricceri, F., Santos, E., Smit, J.H., Soranzo, N., Song, K., Sovio, U., Stumvoll, M., Surakk, I., Thorgeirsson, T.E., Thorsteinsdottir, U., Troakes, C., Tyrfingsson, T., Tönjes, A., Uiterwaal, C.S., Uitterlinden, A.G., van der Harst, P., van der Schouw, Y.T., Staehlin, O., Vogelzangs, N., Vollenweider, P., Waeber, G., Wareham, N.J., Waterworth, D.M., Whitfield, J.B., Wichmann, E.H., Willemsen, G., Witteman, J.C., Yuan, X., Zhai, G., Zhao, J.H., Zhang, W., Martin, N.G., Metspalu, A., Doering, A., Scott, J., Spector, T.D., Loos, R.J., Boomsma, D.I., Mooser, V., Peltonen, L., Stefansson, K., van Duijn, C.M., Vineis, P., Sommer, W.H., Kooner, J.S., Spanagel, R., Heberlein, U.A., Jarvelin, M.R., and Elliott, P. (2011).
Genome-wide associations and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption.
Proceeding of the National Academy of Sciences USA 108(17):7119-7124. PMID: 3084048. (pdf file and supplement)

Zlojutro, M., Manz, N., Rangaswamy, M., Xuei, X.,  Flury-Wetherill, L., Koller, D., Bierut, L.J.,  Goate, A., Hesselbrock, V., Kuperman, S., Nurnberger, J., Jr., Rice, J.P., Schuckit, M.A., Foroud, T., Edenberg, H.J., Porjesz, B., and Almasy, L. (2011).
Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 156B(1):44-58. PMCID: PMC3139811, PMID: 21184583. (pdf file)

2010

*** Anney, R., Klei, L., Pinto, D., Regan, R., Conroy, J., Magalhaes, T.R., Correia, C., Abrahams, B.S., Sykes, N., Pagnamenta, A.T., Almeida, J., Bacchelli, E., Bailey, A.J., Baird, G., Battaglia, A., Berney, T., Bolshakova, N., Bolte, S., Bolton, P.F., Bourgeron, T., Brennan, S., Brian, J., Carson, A.R., Casallo, G., Casey, J., Chu, S.H., Cochrane, L., Corsello, C., Crawford, E.L., Crossett, A., Dawson, G., de Jonge, M., Delorme, R., Drmic, I., Duketis, E., Duque, F., Estes, A., Farrar, P., Fernandez, B.A., Folstein, S.E., Fombonne, E., Freitag, C.M., Gilbert, J., Gillberg, C., Glessner, J.T., Goldberg, J., Green, J., Guter, S.J., Hakonarson, H., Heron, E.A., Hill, M., Holt, R., Howe, J.L., Hughes, G., Hus, V., Igliozzi, R., Kim, C., Klauck, S.M., Kolevzon, A., Korvatska, O., Kustanovich, V., Lajonchere, C.M., Lamb, J.A., Laskawiec, M., Leboyer, M., Le Couteur, A., Leventhal, B.L., Lionel, A.C., Liu, X.Q., Lord, C., Lotspeich, L., Lund, S.C., Maestrini, E., Mahoney, W., Mantoulan, C., Marshall, C.R., McConachie, H., McDougle, C.J., McGrath, J., McMahon, W.M., Melhem, N.M., Merikangas, A., Migita, O., Minshew, N.J., Mirza, G.K., Munson, J., Nelson, S.F., Noakes, C., Noor, A., Nygren, G., Oliveira, G., Papanikolaou, K., Parr, J.R., Parrini, B., Paton, T., Pickles, A., Piven, J., Osey, D.J., Poustka, A., Poustka, F., Prasad, A., Ragoussis, J., Renshaw, K., Rickaby, J., Roberts, W., Roeder, K., Roge, B., Rutter, M.L., Bierut, L.J., Rice, J.P., Salt, J., Sansom, K., Sato, D., Segurado, R., Senman, L., Shah, N., Sheffield, V.C., Soorya, L., Sousa, I., Stoppioni, V., Strawbridge, C., Tancredi, R., Tansey, K., Thiruvahindrapduram, B., Thompson, A.P., Thomson, S., Tryfon, A., Tsiantis, J., Van Engeland, H., Vincent, J.B., Volkmar, F., Wallace, S., Wang, K., Wang, Z.Z., Wassink, T.H., Wing, K., Wittemeyer, K., Wood, S., Yaspan, B.L., Zurawiecki, D., Zwaigenbaum, L., Betancur, C., Buxbaum, J.D., Cantor, R.M., Cook, E.H., Coon, H., Cuccaro, M.L., Gallagher, L., Geschwind, D.H., Gill, M., Haines, J.L., Miller, J., Monaco, A.P., Nurnberger, J.I., Paterson, A.D., Pericak-Vance, M.A., Schellenberg, G.D., Scherer, S.W., Sutcliffe, J.S., Szatmari, P., Vicente, A.M., Vieland, V.J., Wijsman, E.M., Devlin, B., Ennis, S., and Hallmayer, J. (2010).
A genome-wide scan for common alleles affecting risk for autism.
Human Molecular Genetics 19(20):4072-4082. PMCID: PMC2947401. (pdf file)

Bauer, L., Dick, D., Bierut, L., Bucholz, K., Edenberg, H., Kuperman, S., Kramer, J., Nurnberger, J., O'Connor, S., Rice, J., Rohrbaugh, J., Schuckit, M., Tischfield, J., Porjesz, B. and Hesselbrock, V. (2010).
Obesity, smoking, and frontal brain dysfunction.
The American Journal on Addictions 19(5):391-400. PMCID: PMC2924769. (pdf file)

*** Bierut, L.J., Agrawal, A., Bucholz, K.K., Doheny, K.F., Laurie, C., Pugh, E., Fisher, S., Fox, L., Howells, W., Bertelsen, S., Hinrichs, A.L., Almasy, L., Breslau, N., Culverhouse, R.C., Dick, D.M., Edenberg, H.J., Foroud, T., Grucza, R.A., Hatsukami, D., Hesselbrock, V., Johnson, E.O., Kramer, J., Krueger, R.F., Kuperman, S., Lynskey, M., Mann, K., Neuman, R.J., Nöthen, M.M., Nurnberger, J.I. Jr, Porjesz, B., Ridinger, M., Saccone, N.L., Saccone, S.F., Schuckit, M.A., Tischfield, J.A., Wang, .J.C, Rietschel, M., Goate, A.M., and Rice, J.P., as part of the Gene, Environment Association Studies (GENEVA) Consortium (2010).
A genome-wide association study of alcohol dependence.
Proceedings of the National Academy of Sciences of the United States of America 107(11):5082-5087. PMCID: PMC2841942. (pdf file and supplement)

Cavazos-Rehg, P.A. Spitznagel, E.L., Bucholz, K.K., Nurnberger, J., Jr., Edenberg, H.J., Kramer, J.R., Kuperman, S., Hesselbrock, V., and Bierut, L.J. (2010).
Predictors of sexual debut at age 16 or younger.

Archives of Sexual Behavior 39(3):664-673. PMCID: PMC2855761, PMID: 18846417. (pdf file)

Chen, A.C., Manz, N., Tang, Y., Rangaswamy, M., Almasy, L., Kuperman, S., Nurnberger, J., Jr., O'Connor, S.J., Edenberg, H.J., Schuckit, M.A., Tischfield, J., Foroud, T., Bierut, L.J., Rohrbaugh, J., Rice, J.P., Goate, A., Hesselbrock, V., and Porjesz, B. (2010).
Single nucleotide polymorphisms in corticotropin releasing hormone receptor 1 gene (CRHR1) are associated with quantitative traits of event-related potential and alcohol dependence.
Alcoholism: Clinical and Experimental Research 34(6):988-996. PMCID: PMC 2878886, PMID: 20374216. (pdf file)

*** Cornelis, M.C., Agrawal, A., Cole, J.W., Hansel, N.N., Barnes, K.C., Beaty, T.H., Bennett, S.N., Bierut, L.J., Boerwinkle, E., Doheny, K.F., Feenstra, B., Feingold, E., Fornage, M., Haiman, C.A., Harris, E.L., Hayes, M.G., Heit, J.A., Hu, F.B., Kang, J.H., Laurie, C.C., Ling, H., Manolio, T.A., Marazita, M.L., Mathias, R.A., Mirel, D.B., Paschall, J., Pasquale, L.R., Pugh, E.W., Rice, J.P., Udren, J., van Dam, R.M., Wang, X., Wiggs, J.L., Williams, K., and Yu, K.; GENEVA Consortium (2010).
The Gene, Environment Association Studies consortium (GENEVA): Maximizing the knowledge obtained from GWAS by collaboration across studies of multiple conditions.
Genetic Epidemiology, 34(4):364-372. PMCID: PMC2860056. (pdf file)

*** Derringer, J., Krueger, R.F., Dick, D.M., Saccone, S., Grucza, R.A., Agrawal, A., Lin, P., Almasy, L., Edenberg, H.J., Foroud, T., Nurnberger, J.I., Jr., Hesselbrock, V.M., Kramer, J.R., Kuperman, S., Porjesz, B., Schuckit, M.A., and Bierut, L.J.; Gene Environment Association Studies (GENEVA) Consortium (2010).
Predicting sensation seeking from dopamine genes: A candidate-system approach.
Psychological Science 21(9):1282-1290. PMCID: PMC3031097. (pdf file)

Dick, D.M., Meyers, J., Aliev, F., Nurnberger, J., Jr., Kramer, J., Kuperman, S., Porjesz, B., Tischfield, J., Edenberg, H.J., Foroud, T., Schuckit, M., Goate, A., Hesselbrock, V., and Bierut, L. (2010).
Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts.
Neuropsychiatric Genetics Part B: American Journal of Medical Genetics 153B(6):1179-1188. PMID: 20468071. (pdf file)

Dick, D.M., Smith, G., Olausson, P., Mitchell, S.H., Leeman, R.F., O'Malley, S.S., and Sher, K. (2010).
Understanding the construct of impulsivity and its relationship to alcohol use disorders.
Addiction Biology 15(2):217-226. PMCID: PMC2895996 (pdf file)

Edenberg, H.J., Koller, D.L., Xuei, X., Wetherill, L., McClintick, J.N., Almasy, L., Bierut, L.J., Bucholz, K.K., Goate, A., Aliev, F., Dick, D., Hesselbrock, V., Hinrichs, A., Kramer, J., Kuperman, S., Nurnberger, J.I., Jr., Rice, J.P., Schuckit, M.A., Taylor, R., Todd Webb, B., Tischfield, J.A., Porjesz, B., and Foroud, T. (2010).
Genome-wide association study of alcohol dependence implicates a region on chromosome 11.
Alcoholism: Clinical and Experimental Research 34(5):840-852. PMCID: PMC2884073. (pdf file)

*** Elks, C.E., Perry, J.R., Sulem, P., Chasman, D.I., Franceschini, N., He, C., Lunetta, K.L., Visser, J.A., Byrne, E.M., Cousminer, D.L., Gudbjartsson, D.F., Esko, T., Feenstra, B., Hottenga, J.J., Koller, D.L., Kutalik, Z., Lin, P., Mangino, M., Marongiu, M., McArdle, P.F., Smith, A.V., Stolk, L., van Wingerden, S.H., Zhao, J.H., Albrecht, E., Corre, T., Ingelsson, E., Hayward, C., Magnusson, P.K., Smith, E.N., Ulivi, S., Warrington, N.M., Zgaga, L., Alavere, H., Amin, N., Aspelund, T., Bandinelli, S., Barroso, I., Berenson, G.S., Bergmann, S., Blackburn, H., Boerwinkle, E., Buring, J.E., Busonero, F., Campbell, H., Chanock, S.J., Chen, W., Cornelis, M.C., Couper, D., Coviello, A.D., d'Adamo, P., de Faire, U., de Geus, E.J., Deloukas, P., Döring, A., Smith, G.D., Easton, D.F., Eiriksdottir, G., Emilsson, V., Eriksson, J., Ferrucci, L., Folsom, A.R., Foroud, T., Garcia, M., Gasparini, P., Geller, F., Gieger, C.; GIANT Consortium, Gudnason, V., Hall, P., Hankinson, S.E., Ferreli, L., Heath, A.C., Hernandez, D.G., Hofman, A., Hu, F.B., Illig, T., Järvelin, M.R., Johnson, A.D., Karasik, D., Khaw, K.T., Kiel, D.P., Kilpeläinen, T.O., Kolcic, I., Kraft, P., Launer, L.J., Laven, J.S., Li, S., Liu, J., Levy, D., Martin, N.G., McArdle, W.L., Melbye, M., Mooser, V., Murray, J.C., Murray, S.S., Nalls, M.A., Navarro, P., Nelis, M., Ness, A.R., Northstone, K., Oostra, B.A., Peacock, M., Palmer, L.J., Palotie, A., Paré, G., Parker, A.N., Pedersen, N.L., Peltonen, L., Pennell, C.E., Pharoah, P., Polasek, O., Plump, A.S., Pouta, A., Porcu, E., Rafnar, T., Rice, J.P., Ring, S.M., Rivadeneira, F., Rudan, I., Sala, C., Salomaa, V., Sanna, S., Schlessinger, D., Schork, N.J., Scuteri, A., Segrè, A.V., Shuldiner, A.R., Soranzo, N., Sovio, U., Srinivasan, S.R., Strachan, D.P., Tammesoo, M.L., Tikkanen, E., Toniolo, D., Tsui, K., Tryggvadottir, L., Tyrer, J., Uda, M., van Dam, R.M., van Meurs, J.B., Vollenweider, P., Waeber, G., Wareham, N.J., Waterworth, D.M., Weedon, M.N., Wichmann, H.E., Willemsen, G., Wilson, J.F., Wright, A.F., Young, L., Zhai, G., Zhuang, W.V., Bierut, L.J., Boomsma, D.I., Boyd, H.A., Crisponi, L., Demerath, E.W., van Duijn, C.M., Econs, M.J., Harris, T.B., Hunter, D.J., Loos, R.J., Metspalu, A., Montgomery, G.W., Ridker, P.M., Spector, T.D., Streeten, E.A., Stefansson, K., Thorsteinsdottir, U., Uitterlinden, A.G., Widen, E., Murabito, J.M., Ong, K.K., and Murray, A. (2010).
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.
Nature Genetics 42(12):1077-1085. PMCID: PMC3140055. (pdf file and supplemantary pdf files and excel file)

Foroud, T., Edenberg, H.J., and Crabbe, J.C. (2010).
Genetic research: Who is at risk for alcoholism?
Alcohol Research & Health 33(1 and 2):64-75. (pdf file)

Grucza, R.A., Krueger, R.F., Racette, S.B., Norberg, K.E., Hipp, P.R., and Bierut, L.J. (2010).
The emerging link between alcoholism risk and obesity in the United States.
Archives of Genetic Psychiatry
67(12):1301-1308. PMCID: PMC3110764. (pdf file)

Hartz, S.M. and Bierut, L.J. (2010).
Genetics of addictions.
Journal of Laboratory and Clinical Medicine 30(4):847-864. PMCID: PMC3047506. (pdf file)

Jonson-Reid, M., Presnall, N., Drake, B., Fox, L., Bierut, L., Reich, W., Kane, P., Todd, R.D., and Constantino, J.N. (2010).
Effects of child maltreatment and inherited liability on antisocial development: an official records study.
Journal of the American Academy of Child and Adolescent Psychiatry 49(4):321-32. PMCID: PMC2878182. (pdf file)

Kalsi, G., Kuo, P.H., Aliev, F., Alexander, J., McMichael, O., Patterson, D.G., Walsh, D., Zhao, Z., Schuckit, M., Nurnberger, J., Jr., Edenberg, H., Kramer, J., Hesselbrock, V., Tischfield, J.A., Vladimirov, V., Prescott, C.A., Dick, D.M., Kendler, K.S., and Riley, B.P. (2010).
A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.
Human Molecular Genetics
19(12):2497-506. PMCID: PMC2876884. (pdf file)

Kamarajan, C., Rangaswamy, M., Tang, Y., Chorlian, D.B., Pandey, A.K., Roopesh, B.N., Manz, N., Saunders, R., Stimus, A.T., and Porjesz, B. (2010).
Dysfunctional reward processing in male alcoholics: An ERP study during a gambling task.
Journal of Psychiatric Research 44(9):576-590. PMCID: PMC2878886. (pdf file)

Kramer, J., Chan, G., Hesselbrock, V.M., Kuperman, S., Bucholz, K.K., Edenberg, H.J., Schuckit, M., Nurnberger, J., Jr., Foroud, T., Dick, D.M., Bierut, L., and Porjesz, B. (2010).
A principle components analysis of the abbreviated desires for alcohol questionnaire (DAQ).
Journal of Studies on Alcohol and Drugs 71(1):150-155. PMCID: PMC2815057. (pdf file)

*** Laurie, C.C., Doheny, K.F., Mirel, D.B., Pugh, E.W., Bierut, L.J., Bhangale, T., Boehm, F., Caporaso, N.E., Cornelis, M.C., Edenberg, H.J., Gabriel, S.B., Harris, E.L., Hu, F.B., Jacobs, K.B., Kraft, P., Landi, M.T., Lumley, T., Manolio, T.A., McHugh, C., Painter, I., Paschall, J., Rice, J.P., Rice, K.M., Zheng, X., Weir, B.S., and GENEVA Investigators. (2010).
Quality control and quality assurance in genotypic data for genome-wide association studies.
Genetic Epidemiology 34(6):591-602. PMCID: PMC3061487. (pdf file)

*** Lin, P., Hartz, S.M., Zhang, Z., Saccone, S.F., Wang, J., Tischfield, J.A., Edenberg, H.J., Kramer, J.R., M. Goate, A., Bierut, L.J., Rice, J.P., COGA Collaborators, COGEND Collaborators, and GENEVA (2010).
A new statistic to evaluate imputation reliability.
PLoS ONE 5(3):e9697. PMCID: PMC2837741. (pdf file)

Meyers, J.L. and Dick, D.M. (2010).

Genetic and environmental risk factors for youth adolescent onset substance use disorders.

Child and Adolescent Psychiatric Clinics of North America 19(3):465-477. PMCID: PMC20682215.

*** Noor, A., Whibley A, Marshall CR, Gianakopoulos PJ, Piton A, Carson AR, Orlic-Milacic M, Lionel AC, Sato D, Pinto D, Drmic I, Noakes C, Senman L, Zhang X, Mo R, Gauthier J, Crosbie J, Pagnamenta AT, Munson J, Estes AM, Fiebig A, Franke A, Schreiber S, Stewart AF, Roberts R, McPherson R, Guter SJ, Cook EH, Jr., Dawson G, Schellenberg GD, Battaglia A, Maestrini E, Jeng L, Hutchison T, Rajcan-Separovic E, Chudley AE, Lewis SM, Liu X, Holden JJ, Fernandez B, Zwaigenbaum L, Bryson SE, Roberts W, Szatmari P, Gallagher L, Stratton MR, Gecz J, Brady AF, Schwartz CE, Schachar RJ, Monaco AP, Rouleau GA, Hui CC, Lucy Raymond F, Scherer SW, Vincent JB (2010).
Disruption at the PTCHD1 Locus on Xp22.11 in Autism spectrum disorder and intellectual disability.
Science Translational Medicine 2(49):49ra68. PMCID: PMC2987731. (pdf file)

*** Pinto, D., Pagnamenta, A.T., Klei, L., Anney, R., Merico, D., Regan, R., Conroy, J., Magalhaes, T.R., Correia, C., Abrahams, B.S., Almeida, J., Bacchelli, E., Bader, G.D., Bailey, A.J., Baird, G., Battaglia, A., Berney, T., Bolshakova, N., Bölte, S., Bolton, P.F., Bourgeron, T., Brennan, S., Brian, J., Bryson, S.E., Carson, A.R., Casallo, G., Casey, J., Chung, B.H., Cochrane, L., Corsello, C., Crawford, E.L., Crossett, A., Cytrynbaum, C., Dawson, G., de Jonge, M., Delorme, R., Drmic, I., Duketis, E., Duque, F., Estes, A., Farrar, P., Fernandez, B.A., Folstein, S.E., Fombonne, E., Freitag, C.M., Gilbert, J., Gillberg, C., Glessner, J.T., Goldberg, J., Green, A., Green, J., Guter, S.J., Hakonarson, H., Heron, E.A., Hill, M., Holt, R., Howe, J.L., Hughes, G., Hus, V., Igliozzi, R., Kim, C., Klauck, S.M., Kolevzon, A., Korvatska, O., Kustanovich, V., Lajonchere, C.M., Lamb, J.A., Laskawiec, M., Leboyer, M., Le Couteur, A., Leventhal, B.L., Lionel, A.C., Liu, X.Q., Lord, C., Lotspeich, L., Lund, S.C., Maestrini, E., Mahoney, W., Mantoulan, C., Marshall, C.R., McConachie, H., McDougle, C.J., McGrath, J., McMahon, W.M., Merikangas, A., Migita, O., Minshew, N.J., Mirza, G.K., Munson, J., Nelson, S.F., Noakes, C., Noor, A., Nygren, G., Oliveira, G., Papanikolaou, K., Parr, J.R., Parrini, B., Paton, T., Pickles, A., Pilorge, M., Piven, J., Ponting, C.P., Posey, D.J., Poustka, A., Poustka, F., Prasad, A., Ragoussis, J., Renshaw, K., Rickaby, J., Roberts, W., Roeder, K., Roge, B., Rutter, M.L., Bierut, L.J., Rice, J.P., Salt, J., Sansom, K., Sato, D., Segurado, R., Sequeira, A.F., Senman, L., Shah, N., Sheffield, V.C., Soorya, L., Sousa, I., Stein, O., Sykes, N., Stoppioni, V., Strawbridge, C., Tancredi, R., Tansey, K., Thiruvahindrapduram, B., Thompson, A.P., Thomson, S., Tryfon, A., Tsiantis, J., Van Engeland, H., Vincent, J.B., Volkmar, F., Wallace, S., Wang, K., Wang, Z., Wassink, T.H., Webber, C., Weksberg, R., Wing, K., Wittemeyer, K., Wood, S., Wu, J., Yaspan, B.L., Zurawiecki, D., Zwaigenbaum, L., Buxbaum, J.D., Cantor, R.M., Cook, E.H., Coon, H., Cuccaro, M.L., Devlin, B., Ennis, S., Gallagher, L., Geschwind, D.H., Gill, M., Haines, J.L., Hallmayer, J., Miller, J., Monaco, A.P., Nurnberger, J.I., Jr., Paterson, A.D., Pericak-Vance, M.A., Schellenberg, G.D., Szatmari, P., Vicente, A.M., Vieland, V.J., Wijsman, E.M., Scherer, S.W., Sutcliffe, J.S., and Betancur, C. (2010).
Functional impact of global rare copy number variation in autism spectrum disorders.
Nature 466(7304):368-372. PMCID: PMC3021798.

Saccone, S.F., Bolze, R., Thomas, P., Quan, J., Mehta, G., Deelman, E., Tischfield, J.A., and Rice, J.P. (2010).
SPOT: a web-based tool for using biological databases to prioritize SNPs after a genome-wide association study.
Nucleic acids research, 38(Web Server issue):W201-9. PMCID: PMC2896195. (pdf file)

*** Saccone NL, Culverhouse RC, Schwantes-An TH, Cannon DS, Chen X, Cichon S, Giegling I, Han S, Han Y, Keskitalo-Vuokko K, Kong X, Landi MT, Ma JZ, Short SE, Stephens SH, Stevens VL, Sun L, Wang Y, Wenzlaff AS, Aggen SH, Breslau N, Broderick P, Chatterjee N, Chen J, Heath AC, Heliovaara M, Hoft NR, Hunter DJ, Jensen MK, Martin NG, Montgomery GW, Niu T, Payne TJ, Peltonen L, Pergadia ML, Rice JP, Sherva R, Spitz MR, Sun J, Wang JC, Weiss RB, Wheeler W, Witt SH, Yang BZ, Caporaso NE, Ehringer MA, Eisen T, Gapstur SM, Gelernter J, Houlston R, Kaprio J, Kendler KS, Kraft P, Leppert MF, Li MD, Madden PA, Nothen MM, Pillai S, Rietschel M, Rujescu D, Schwartz A, Amos CI, Bierut LJ (2010).
Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.
PLoS Genetics 6(8)e1001053. PMCID: PMC2916847. (pdf file)

*** Thornton T, McPeek MS (2010).
ROADTRIPS: case-control association testing with partially or completely unknown population and pedigree structure.
American Journal of Human Genetics 86(2):172-84. PMCID: PMC2820184. (pdf file)

Xuei, X., Flury-Wetherill, L., Dick, D., Goate, A., Tischfield, J., Nurnberger, J., Jr., Schuckit, M., Kramer, J., Kuperman, S., Hesselbrock, V., Porjesz, B., Foroud, T., and Edenberg, H.J. (2010).
GABRR1 and GABRR2, encoding the GABA-A receptor subunits r1 and r2, are associated with alcohol dependence.
American Journal of Medical Genetics B: Neuropsychiatric Genetics 153B(2):418-427. PMCID: PMC2829340. (pdf file)

2009

Agrawal, A., Wetherill, L., Dick, D.M., Xuei, X., Hinrichs, A.L., Hesselbrock, V., Kramer, J.,Nurnberger, J.I., Jr., Schuckit, M.A., Bierut., L.J., Edenberg, H.J., and Foroud, T. (2009).
Evidence for association between polymorphisms in the cannabinoid receptor 1 (CNR1) gene and cannabis dependence.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 150B(5):736-740. PMID: 19536785, PMCID: PMC2703788. (pdf file)

Cavazos-Rehg, P.A., Spitznagel, E.L., Schootman, M., Strickland, J.R., Afful, S.E., Cottler, L.B., and Bierut, L.J. (2010).

Risky sexual behaviours and sexually transmitted diseases: A comparison study of cocaine-dependent individuals in treatment versus a community-matched sample.

AIDS Patient Care and STDs 23(9):727-734. PMCID: PMC2804246. (pdf file)

Chen, A., Tang, Y., Rangaswamy, M., Almasy, L., Kuperman, S., Nurnberger, J., Jr., O'Connor, S., Edenberg, H., Schuckit, M., Tischfield, J., Foroud, T., Bierut, L., Rohrbaugh, J., Bauer, L., Rice, J., Hesselbrock, V., Goate, A., and Porjesz, B. (2009).
Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event-related oscillations and alcohol dependence.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 150B(3):359-368. PMCID:PMC2660384. (pdf file)

Chorlian, D.B., Rangaswamy, M., and Porjesz, B. (2009).
EEG coherence: Topography and frequency structure.
Experimental Brain Research 198(1):59-83. PMID: 19626316. (pdf file)

Grucza, R., Norberg, K., and Bierut, L. (2009).
Binge drinking among youth and young adults in the United States: 1979-2006.
Journal of American Academy of Child and Adolescent Psychiatry 48(7):692-702. PMID: 19465879, PMCID: PMC2862553. (pdf file)

Hurley, J., Ballard, C., and Edenberg, H. (2009).

Altering the relative abundance of GABA A receptor subunits changes GABA- and ethanol-responses in Xenopus oocytes.

Alcoholism: Clinical and Experimental Research 33(6):1089-1096. PMID: 19382902. (pdf file)

Kamarajan, C., Porjesz, B., Rangaswamy, M., Tang, Y., Chorlian, D.B., Padmanabhapillai, A., Saunders, R., Pandey, A.K., Roopesh, B.N., Manz, N., Stimus, A.T., and Begleiter, H. (2009).
Brain signatures of monetary loss and gain: Outcome-related potentials in a single outcome gambling task.
Behavioral Brain Research 197(1):62-76. PMCID: PMC2645043. (pdf file)

Kramer, J., Chan, G., Kuperman, S., Bucholz, K., Edenberg, H., Schuckit, M., Polgreen, L., Kapp, E., Hesselbrock, V., Nurnberger, J., Jr., and Bierut, L. (2009).
A comparison of diagnoses obtained from in-person and telephone interviews, using the semi-structured assessment for the genetics of alcoholism (SSAGA).
Journal of Studies on Alcohol and Drugs 70(4):623-627. PMCID: PMC2696302. (pdf file)

Lester, H.A., Xiao, C., Srinivasan, R., Son, C.D., Miwa, J., Pantoja, R., Banghart, M.R., Dougherty, D.A., Goate, A.M., and Wang, J.C. (2009).
Nicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry. Implications for drug discovery.
American Association of Pharmaceutical Scientists Journal 11(1):167-177. PMCID: PMC2664890 (pdf file)

McCutcheon, V., Heath, A., Edenberg, H., Grucza, R., Hesselbrock, V., Kramer, J., Bierut, L., and Bucholz, K. (2009).
Alcohol criteria endorsement and psychiatric and drug use disorders among DUI offenders: Greater severity among women and multiple offenders.
Addictive Behaviors 34(5):432-439. PMID: 19167170, PMCID: PMC2855219. (pdf file)

Norberg, K.E., Bierut, L.J., and Grucza, R.A. (2009).
Long-term effects of minimum drinking age laws on past-year alcohol and drug use disorders.
Alcoholism: Clinical and Experimental Research
33(12):2180-2190. PMCID: PMC3018854. (pdf file)

Roopesh, B.N., Rangaswamy, M., Kamarajan, C., Chorlian, D.B., Stimus, A.T., Bauer, L.O., Rohrbaugh, J. O'Connor, S.J., Kuperman, S., Schuckit, M., and Porjesz, B. (2009).
Priming deficiency in male subjects at risk for alcoholism: The N4 during a lexical decision task.
Alcoholism: Clinical and Experimental Research 33(12):2027-2036. PMID: 19764939, PMCID: PMC2924769. (pdf file)

Schuckit, M.A. (2009).

Alcohol-use disorders.

Lancet 373(9662):492-501. PMID: 19168210. (pdf file)

Schuckit, M.A., Smith, T.L., Danko, G.P., Trim, R., Bucholz, K.K., Edenberg, H.J., Hesselbrock, V., Kramer, J.J., and Dick, D.M. (2009).

An evaluation of the full level of response to alcohol model of heavy drinking and problems in COGA offspring.

Journal of Studies on Alcohol and Drugs 70(3):436-445. PMCID: PMC2670749. (pdf file)

Schuckit, M.A., Smith, T.L., Trim, R., Fukukura, T., and Allen, R. (2009)

The overlap in predicting alcohol outcome for two measures of the level of response to alcohol.

Alcoholism: Clinical and Experimental Research 33(3):563-569. PMCID: PMC2651993, NIHMSID: 84626. (pdf file)

Wang, J.C., Cruchaga, C., Saccone, N.L., Bertelsen, S., Liu, P., Budde, J.P., Duan, W., Fox, L., Grucza, R.A., Kern, J., Mayo, K., Reyes, O., Rice, J., Saccone, S.F., Spiegel, N., Steinbach, J.H., Stitzel, J.A., Anderson, M.W., You, M., Stevens, V.L., Bierut, L.J., and Goate, A.M.; COGEND collaborators, and GELCC collaborators (2009).
Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.
Human Molecular Genetics 18(16):3125-3135. PMCID: PMC2714722. (pdf file)

Wang, J.C., Grucza, R., Cruchaga, C., Hinrichs, A.L., Bertelsen, S., Budde, J.P., Fox, L., Goldstein, E., Reyes, O., Saccone, N., Saccone, S., Xuei, X., Bucholz, K., Kuperman, S., Nurnberger, J., Jr., Rice, J.P., Schuckit, M., Tischfield, J., Hesselbrock, V., Porjesz, B., Edenberg, H.J., Bierut, L.J., and Goate, A.M. (2009).
Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence.
Molecular Psychiatry 14(5):501-510. PMID: 18414406. (pdf file)

2008

Agrawal, A., Hinrichs, A.L., Dunn, G., Bertelsen, S., Dick, D.M., Saccone, S.F., Saccone, N.L., Grucza, R.A., Wang, J.C., Cloninger, C.R., Edenberg, H.J., Foroud, T., Hesselbrock, V., Kramer, J., Bucholz, K.K., Kuperman, S., Nurnberger, J.I., Jr, Porjesz, B., Schuckit, M.A., Goate, A.M., and Bierut., L.J. (2008).
Linkage scan for quantitative traits identifies new regions of interest for substance dependence in the Collaborative Study on the Genetics of Alcoholism (COGA) sample.
Drug and Alcohol Dependence 93(1-2):12-20. PMCID: PMC2266629. (pdf file)

Bierut, L.J., Stitzel, J.A., Wang, J.C., Hinrichs, A.L., Grucza, R.A., Xuei, X., Saccone, N.L., Saccone, S.F., Bertelsen, S., Fox, L., Horton, W.J., Breslau, N., Budde, J., Cloninger, C.R., Dick, D.M., Foroud, T., Hatsukami, D., Hesselbrock, V., Johnson, E.O., Kramer, J., Kuperman, S., Madden, P.A.F., Mayo, K., Nurnberger, J., Jr, Pomerleau, O., Porjesz, B., Reyes, O., Schuckit, M., Swan, G., Tischfield, J.A., Edenberg, H.J., Rice, J.P., and Goate, A.M. (2008).
Variants in nicotinic receptors and risk for nicotine dependence.
American Journal of Psychiatry 165(9):1163-1171. PMCID: PMC2574742. (pdf file)

Dick, D. and Agrawal, A. (2008).

The genetics of alcohol and other drug dependence.

Alcohol Resarch & Health 31(2):111-118.

Dick, D.M., Aliev, F., Wang, J.C., Grucza, R.A., Schuckit, M., Kuperman, S., Kramer, J., Hinrichs, A., Bertelsen, S., Budde, J.P., Hesselbrock, V., Porjesz, B., Edenberg, H.J., Bierut, L.J., and Goate, A. (2008)
Using dimensional models of externalizing psychopathology to aid in gene identification.
Archives of General Psychiatry 65(3):310-318. PMID: 18316677. (pdf file)

Dick, D.M., Aliev, F., Wang, J.C., Saccone, S., Hinrichs, A., Bertelsen, S., Budde, J., Saccone, N., Foroud, T., Nurnberger, J., Jr., Xuei, X., Conneally, P.M., Schuckit, M., Almasy, L., Crowe, R., Kuperman, S., Kramer, J., Tischfield, J.A., Hesselbrock, V., Edenberg, H.J., Porjesz, B., Rice, J.P., Bierut, L., and Goate, A. (2008).
A systematic single nucleotide polymorphism screen to fine-map alcohol dependence genes on chromosome 7 identifies association with a novel susceptibility gene ACN9.
Biological Psychiatry 63(11):1047-1053. PMID: 18163977. (pdf file)

Edenberg, H.J., Wang, J., Tian, H., Pochareddy, S., Xuei, X., Wetherill, L., Goate, A., Hinrichs, T., Kuperman, S., Nurnberger, J.I., Jr., Schuckit, M., Tischfield, J.A., and Foroud, T. (2008).
A regulatory variation in OPRK1, the gene encoding the k-opioid receptor, is associated with alcohol dependence.
Human Molecular Genetics 17(12):1783-1789. PMCID: PMC2405904 , PMID: 18319328. (pdf file)

Edenberg, H.J., Xuei, X.L., Wetherill, L.F., Bierut, L., Bucholz, K., Dick, D.M., Hesselbrock, V., Kuperman, S., Porjesz, B., Schuckit, M.A., Tischfield, J.A., Almasy, L.A., Nurnberger, J.I., and Foroud, T. (2008).
Association of NFKB1, which encodes a subunit of the transcription factor NF-κB, with alcohol dependence.
Human Molecular Genetics 17(7):963-970. PMID: 18079108. (pdf file)

Foroud, T., Flury-Wetherill, L., Kramer, J., Tischfield, J., Nurnberger, J., Jr., Schuckit, M., Xuei, X., and Edenberg, H. (2008).
The tachykinin receptor 3 (Tacr3) is associated with alcohol and cocaine dependence.
Alcoholism: Clinical and Experimental Research 32(6):1023-1030. PMCID: PMC2430628, PMID: 18422838. (pdf file)

Ghosh, S., Bierut, L.J., Porjesz, B., Edenberg, H.J., Dick, D., Goate, A., Hesselbrock, V., Nurnberger, J. Jr, Foroud, T., Kramer, J., Rice, J., and Begleiter, H. (2008).
A novel non-parametric regression reveals linkage on chromosome 4 for the number of externalizing symptoms in sib-pairs.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 147B:1301-1305. PMCID: PMC2879266. (pdf file)

Grucza, R., Bucholz, K., Rice, J., and Bierut, L. (2008).

Secular trends in the lifetime prevalence of alcohol dependence in the United States: A re-evaluation.

Alcoholism: Clinical and Experimental Research 32(5):763-770. PMCID: PMC2443101, PMID: 18336633. (pdf file)

Grucza, R., Norberg, K., Bucholz, K., and Bierut, L. (2008).
Correspondence between secular changes in alcohol dependence and age of drinking onset among women in the United States.
Alcoholism: Clinical and Experimental Research 32(8):1493-1501. PMCID: PMC2661151, PMID: 18564104. (pdf file)

Grucza, R.A., Wang, J.C., Stitzel, J.A., Hinrichs, A.L., Saccone, S.F., Saccone, N.L., Bucholz, K.K., Cloninger, C.R., Neuman, R.J., Budde, J.P., Fox, L., Bertelsen, S., Kramer, J., Hesselbrock, V., Tischfield, J., Nurnberger, J.I., Jr., Almasy, L., Porjesz, B., Kuperman, S., Schuckit, M.A., Edenberg, H.J., Rice, J.P., Goate, A.M., and Bierut, L.J. (2008).
A risk allele for nicotine dependence in CHRNA5 is a protective allele for cocaine dependence.
Biological Psychiatry 64(11):922-929. PMCID: PMC2582594. (pdf file)

Kramer, J., Chan, G., Dick, D., Kuperman, S., Bucholz, K., Hesselbrock, V., Edenberg, H., Polgreen, L., Hesselbrock, V., Schuckit, M., Nurnberger, J., Jr., Kapp, E., Porjesz, B., and Bierut, L. (2008).
Multiple-domain predictors of problematic alcohol use in young adulthood.
Journal of Studies on Alcohol and Drugs 69(5):649-459. PMCID: PMC2575389. (pdf file)

Mayfield, R.D., Harris, R.A., and Schuckit, M.A. (2008).
Genetic factors influencing alcohol dependence.
British Journal of Pharmacology 154(2):275-287. PMCID: PMC2442454. (pdf file)

Pescosolido, B.A., Perry, B.L., Long, J.S., Martin, J.K., Nurnberger, J.I., Jr., and Hesselbrock, V. (2008).
Under the influence of genetics: How transdisciplinarity leads us to rethink social pathways to illness.
American Journal of Sociology 114 (Suppl):S171-201. PMID: 19569404. (pdf file)

Rangaswamy, M. and Porjesz, B. (2008).
From event-related potential to oscillations: Genetic diathesis in brain (dys)function and alcohol dependence.
Alcohol Research & Health 31(3):238-242. (pdf file)


Rangaswamy, M. and Porjesz, B. (2008).
Uncovering genes for cognitive (dys)function and predisposition for alcoholism spectrum disorders: A review of human brain oscillations as effective endophenotypes.
Brain Research 1235:153-171. PMCID: PMC2814598. (pdf file)

Saccone, S.F., Saccone, N.L., Swan, G.E., Madden, P.A., Goate, A.M., Rice, J.P., and Bierut, L.J. (2008).
Systematic biological prioritization after a genome-wide association study: An application to nicotine dependence.
Bioinformatics 24(16):1805-11. PMCID: PMC2610477. (pdf file)

Schuckit, M., Danko, G., Smith, T., Bierut, L., Bucholz, K., Edenberg, H., Hesselbrock, V., Kramer, J., Nurnberger, J., Jr., Allen, R., Kreikebaum, S., and Hinga, B. (2008).

The prognostic implications of DSM-IV abuse criteria in drinking adolescents.

Drug and Alcohol Dependence 97(1-2):94-104. PMCID: PMC2581466.

Schuckit, M., Smith, T., Hesselbrock, V., Bucholz, K., Bierut, L., Edenberg, H., Kramer, J., Longacre, E., Fukukura, T., Kalmijn, J., Danko, G., and Trim, R. (2008).
Clinical implications of tolerance to alcohol in nondependent young drinkers.
American Journal of Drug and Alcohol Abuse 34(2):133-149. PMID: 18293230.

Wetherill, L., Schuckit, M.A., Hesselbrock, V., Xuei, X., Liang, T., Dick, D.M., Kramer, J., Nurnberger, J.I., Jr., Tischfield, J.A., Porjesz, B., Edenberg, H.J., and Foroud, T. (2008).
Neuropeptide y receptor genes are associated with alcohol dependence, alcohol withdrawal phenotypes, and cocaine dependence.
Alcoholism: Clinical and Experimental Research 32(12):2031-2040. PMCID: PMC2650441. (pdf file)

Xuei, X., Flury-Wetherill, L., Almasy, L., Bierut, L., Tischfield, J., Schuckit, M., Nurnberger, J., Jr., Foroud, T., and Edenberg, H. (2008).
Association analysis of genes encoding the nociceptin receptor (OPRL1) and its endogeneous ligand (PNOC) with alcohol or illicit drug dependence.
Addiction Biology 13(1):80-87. PMID: 17910740.

2007

Cavazos-Regh, P.A., Spitznagel, E.L., Bucholz, K.K., Norberg, K., Reich, W., Nurnberger, J., Jr., Hesselbrock, V., Kramer, J., Kuperman, S., Bierut, L.J. (2007).
The relationship between alcohol problems and dependence, conduct problems and diagnosis, and number of sex partners in a sample of young adults.
Alcoholism: Clinical and Experimental Research 31(12):2046-2052.

Chen, C.T., Wang, J.C., and Cohen, B.A. (2007)
The strength of selection on ultraconserved elements in the human genome.
American Journal of Human Genetics 80:692-704. PMID: 17357075, PMCID: PMC1852725 (pdf file)

Chorlian, D.B., Tang, Y., Rangaswamy, M., O'Connor, S.J., Rohrbaugh, J., Taylor, R., and Porjesz, B. (2007).
Heritability of EEG coherence in a large sib-pair population.
Biological Psychology 75:260-266. (pdf file)

Connor, K., Hesselbrock, V., Meldrum, S., Schuckit, M., Bucholz, K., Gamble, S., Wines, J., and Kramer, J. (2007).
Transitions to, and predictors of, suicidal ideation, plans and unplanned- and planned suicide attempts among 3729 men and women with alcohol dependence.
Journal of Studies on Alcohol and Drugs 68(5):654-662. (pdf file)

Dick, D. (2007).
Identification of genes influencing a spectrum of externalizing psychopathology.
Current Directions in Psychological Science 16(6):331-335.

Dick, D., Agrawal, A., Wang, J., Hinrichs, A., Bertelsen, S., Bucholz, K., Schuckit, M., Kramer, J., Edenberg, H., Nurnberger, J., Jr., Tischfield, J., Goate, A., and Bierut, L. (2007).
Alcohol dependence with comorbid drug dependence: Genetic and phenotypic associations suggest a more severe form of the disorder with stronger genetic contribution to risk.

Addiction 102:1131-1139. (pdf file)

Dick, D.M., Aliev, F., Kramer, J., Wang, J.C., Hinrichs, A., Bertelsen, S., Kuperman, S., Schuckit, M., Nurnberger, J., Edenberg, H.J., Porjesz, B., Begleiter, H., Hesselbrock, V., Goate, A., and Bierut, L. (2007).
Association of CHRM2 with IQ: Converging evidence for a gene influencing intelligence.
Behavior Genetics 37:265-272. (pdf file)

Dick, D., Aliev, F., Wang, J., Saccone, S., Hinrichs, A., Bertelsen, S., Budde, J., Saccone, N., Foroud, T., Nurnberger, J., Jr.. Xuei, X., Conneally, P., Schuckit, M., Almasy, L., Crowe, R., Kuperman, S., Kramer, J., Tischfield, J., Hesselbrock, V., Edenberg, H., Porjesz, B., Rice, J., Bierut, L., and Goate, A. (2007).
A systematic SNP screen to fine-map alcohol dependence genes on chromosome 7 identifies association with a novel susceptibility gene ACN9.
Biological Psychiatry 63(11):1047-1053. PMID: 18163977. (pdf file)

Dick, D., Plunkett, J., Hamlin, D., Nurnberger, J., Jr., Kuperman, S., Schuckit, M., Hesselbrock, V., Edenberg, H., and Bierut, L. (2007).
Association analyses of the serotonin transporter gene with lifetime depression and alcohol dependence in the Collaborative Study on the Genetics of Alcoholism (COGA) sample.
Psychiatric Genetics 17(1):35-38.

Dick, D.M., Wang, J.C., Plunkett, J., Aliev, F., Hinrichs, A., Bertelsen, S., Budde, J.P., Goldstein, E.L., Kaplan, D., Edenberg, H.J., Nurnberger, J. Jr, Hesselbrock, V., Schuckit, M., Kuperman, S., Tischfield, J., Porjesz, B., Begleiter, H., Bierut, L., and Goate, A. (2007).
Family-based association analyses of alcohol dependence phenotypes across DRD2 and neighboring gene ANKK1.
Alcoholism: Clinical and Experimental Research 31:1645-1653. (pdf file)

Foroud, T., Flury-Wetherill, L., Dick, D., Hesselbrock, V., Nurnberger, J., Jr., Kramer, J., Tischfield, J., Schuckit, M., Bierut, L., Xuei, X., and Edenberg, H. (2007).
Lack of association of alcohol dependence and habitual smoking with catechol-O-methyltransferase (COMT).
Alcoholism: Clinical and Experimental Research 31(11):1773-1779. (pdf file)

Foroud, T., Flury-Wetherill, L., Liang, T., Dick, D.M., Hesselbrock, V., Kramer, J., Nurnberger, J.I., Jr., Schuckit, M., Carr, L., Porjesz, B., Xuei, X., and Edenberg, H.J. (2007).
Association of alcohol craving with α-synuclein (SNCA).
Alcoholism: Clinical and Experimental Research 31:537-545. (pdf file)

Helzer, J.E., Bucholz, K.K., and Gossop, M. (2007)
A dimensional option for the diagnosis of substance dependence in DSM-V.
International Journal of Methods in Psychiatric Research 16(Suppl 1):S24-33. PMID: 17623392 (pdf file)

Hesselbrock, V. and Hesselbrock, M. (2007).
Are there empirically supported and clinically useful subtypes of alcohol dependence?
In: Schuckit, M.A., Sirovatka, P. and Regier, D.A. (eds.). Diagnostic issues in substance use disorders.
American Psychiatric Association, 2007, pp 171-182.

Nurnberger, J.I., Jr. and Bierut, L.J. (2007).
Seeking the connections: Alcoholism and our genes.
Scientific American 296(4):46-53.

Nurnberger, J., Jr., Kuperman, S., Flury-Wetherill, L., and Meyer, E. (2007).
Genetics of comorbid mood disorder and alcohol dependence.
Journal of Dual Diagnosis: Research and Practice in Substance Abuse Comorbidity 3(2):31-46.

Porjesz, B. and Li, T.-K. (2007).
Impulsivity and addiction: A tribute to Henri Begleiter.
The Scientific World Journal 7:131-141. (pdf file)

Porjesz, B. and Rangaswamy, M. (2007).
Neurophysiological endophenotypes, CNS disinhibition, and risk for alcohol dependence and related disorders.
The Scientific World Journal 7:121-123. (pdf file)

Rangaswamy, M., Jones, K.A., Porjesz, B., Chorlian, D.B., Padmanabhapillai, A., Kamarajan, C. Kuperman, S., Rohrbaugh, J., O'Connor S., Bauer L.O., Schuckit, M., and Begleiter, H. (2007).
Delta and theta oscillations as risk markers in adolescent offspring of alcoholics.
International Journal of Psychophysiology 63:3-15. (pdf file)

Schuckit, M., Smith, T., Danko, G., Pierson, J., Hesselbrock, V., Bucholz, K., Kramer, J., Kuperman, S., Dietiker, C., Brandon, R., and Chan, G. (2006).
The ability of the self-rating of the effects of alcohol (SRE) scale to predict alcohol-related outcomes five years later.
Journal of Studies on Alcohol and Drugs 68(3):371-378. (pdf file) PMID: 17446976

Schuckit, M., Smith, T., Danko, G., Pierson, J., Trim, R., Nurnberger, J., Jr., Kramer, J., Kuperman, S., Bierut, L., and Hesselbrock, V. (2007).
A comparison of factors associated with substance-induced versus independent depressions.
Journal of Studies on Alcohol and Drugs 68:805-812. (pdf file)

Tang, Y., Chorlian, D.B., Rangaswamy, M., O'Connor S., Taylor, R., Rohrbaugh, J., Porjesz, B., and Begleiter, H. (2007).
Heritability of bipolar EEG spectra in a large sib-pair population.
Behavior Genetics 37:302-313. (pdf file)

Tang, Y., Chorlian, D.B., Rangaswamy, M., Porjesz, B., Bauer, L., Kuperman, S., O'Connor, S., Schuckit, M., Stimus, A., and Begleiter, H. (2007).
Genetic influences on bipolar EEG power spectra.
International Journal of Psychophysiology 657:2-9. (pdf file)

Wang, J., Hinrichs, A., Bertelsen, S., Stock, H., Budde, J., Dick, D., Bucholz, K., Rice, J., Saccone, N., Edenberg, H., Hesselbrock, V., Kuperman, S., Schuckit, M., Bierut, L., and Goate, A. (2007).
Functional variants in TAS2R38 and TAS2R16 influence alcohol consumption in high-risk families of African American origin.
Alcoholism: Clinical and Experimental Research 31:209-215. (pdf file)

Xuei, X., Flury-Wetherill, L., Bierut, L., Dick, D., Nurnberger, J., Jr., Foroud, T., and Edenberg, H. (2007).
The opioid system and alcohol and drug dependence: Family-based association study.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 144B:877-884. (pdf file)

2006

Agrawal, A., Edenberg, H.J., Foroud, T., Bierut, L.J., Dunne, G., Hinrichs, A.L., Nurnberger, J.I., Crowe, R., Kuperman, S., Schuckit, M.A., Begleiter, H., Porjesz, B., and Dick, D.M. (2006).
Association of GABRA2 with drug dependence in the Collaborative Study of the Genetics of Alcoholism sample.
Behavior Genetics 36:640-50. (pdf file)

Begleiter, H. and Porjesz, B. (2006).
Genetics of human brain oscillations.
International Journal of Psychophysiology 60:162-171. (pdf file)

Bucholz, K., Nurnberger, J., Jr., Kramer, J., Hesselbrock, V., Schuckit, M., and Bierut, L. (2006).
Comparison of Psychiatric Diagnoses From Interview with Those From Best-estimate Procedures.
Journal of Studies on Alcohol and Drugs 67(1):157-168. (pdf file)

Connor, K., Hesselbrock, V., Schuckit, M., Hirsch, J., Knox, K., Meldrum, S., Bucholz, K., Kramer, J., Kuperman, S., Preuss, U., and Soyka, M. (2006).
Precontemplated and impulsive suicide attempts among individuals with alcohol dependence.
Journal of Studies on Alcohol and Drugs 67(1):95-101. (pdf file)

Dick, D.M., Agrawal, A., Schuckit, M.A., Bierut, L., Hinrichs, A., Fox, L., Mullaney, J., Cloninger, C.R., Hesselbrock, V., Nurnberger, J.I., Jr., Almasy, L., Foroud, T., Porjesz, B., Edenberg, H., and Begleiter, H. (2006).
Marital status, alcohol dependence, and GABRA2: Evidence for gene-environment correlation and interaction.
Journal of Studies on Alcohol 67:185-194. (pdf file)

Dick, D.M., Aliev, F., Bierut, L., Goate, A., Rice, J., Hinrichs, A., Bertelsen, S., Wang, J.C., Dunn, G., Kuperman, S., Schuckit, M., Nurnberger, J., Jr., Porjesz, B., Begleiter, H., Kramer, J., and Hesselbrock, V. (2006).
Linkage analyses of IQ in the Collaborative Study on the Genetics of Alcoholism (COGA) sample.
Behavior Genetics 36:77-86. (pdf file)

Dick, D. and Bierut, L. (2006).
The genetics of alcohol dependence.
Current Psychiatry Reports 8:151-157.

Dick, D.M., Bierut, L., Hinrichs, A., Fox, L., Bucholz, K.K., Kramer, J., Kuperman, S., Hesselbrock, V., Schuckit, M., Almasy, L., Tischfield, J., Porjesz, B., Begleiter, H., Nurnberger, J., Jr., Xuei, X., Edenberg, H.J., and Foroud, T. (2006).
The role of GABRA2 in risk for conduct disorder and alcohol and drug dependence across developmental stages.
Behavior Genetics 36:577-590. (pdf file)

Dick, D.M., Jones, K., Saccone, N., Hinrichs, A., Wang, J.C., Goate, A., Bierut, L., Almasy, L., Schuckit, M., Hesselbrock, V., Tischfield, J., Foroud, T., Edenberg, H., Porjesz, B., and Begleiter, H. (2006).
Endophenotypes successfully lead to gene identification: Results from the Collaborative Study on the Genetics of Alcoholism.
Behavior Genetics 36:112-126. (pdf file)

Dick, D., Plunkett, J., Flury, L., Xuei, X., Goate, A., Hesselbrock, V., Schuckit, M., Crowe, R., Edenberg, H., and Foroud, T. (2006).
Association between GABRA1 and drinking behaviors in the Collaborative Study on the Genetics of Alcoholism sample.
Alcoholism: Clinical and Experimental Research 30(7):1101-1110. (pdf file)

Duncan, A., Neuman, R., Kramer, J., Kuperman, S., Hesselbrock, V., and Bucholz, K. (2006).
Lifetime psychiatric comorbidity of alcohol dependence and bulimia nervosa in women.
Drug and Alcohol Dependence 84:122-132. (pdf file)

Edenberg, H. and Foroud, T. (2006).
The genetics of alcoholism: Identifying specific genes through family studies.
Addiction Biology 11(3-4):386-396.


Edenberg, H.J., Xuei, X., Chen, H.J., Tian, H., Wetherill, L.F., Dick, D.M., Almasy, L., Bierut, L., Bucholz, K.K., Goate, A., Hesselbrock, V., Kuperman, S., Nurnberger, J., Porjesz, B., Rice, J., Schuckit, M., Tischfield, J., Begleiter, H., and Foroud, T. (2006).
Association of alcohol dehydrogenase genes with alcohol dependence: A comprehensive analysis.
Human Molecular Genetics 15:1539-1549. (pdf file)

Fisher, S., Bucholz, K., Reich, W., Fox, L., Kuperman, S., Kramer, J., Hesselbrock, V., Dick, D., Nurnberger, J.I., Jr., Edenberg, H., and Bierut, L. (2006).
Teenagers are right – parents don't know much: An analysis of adolescent-parent agreement on reports of adolescent substance use, abuse and dependence.
Alcoholism: Clinical and Experimental Research 30(19):1699-1710. (pdf file)

Gogineni, A., King, S., Jackson, K., Kramer, J., Bucholz, K., Chan, G., Iacono, W., Kuperman, S., Larkins, J., Longabaugh, R., McGue, M., Polgreen, L., Sher, K., Stout, R., Strong, D., and Woolard, R. (2006).
Female offspring of alcoholic individuals: Recent findings on alcoholism and psychopathology risks.
Alcoholism: Clinical and Experimental Research 30(2):377-387. (pdf file)

Grucza, R. and Bierut, L. (2006).
Cigarette smoking and the risk for alcohol use disorders among adolescent drinkers.
Alcoholism: Clinical and Experimental Research 30(12):2046-2054. PMID: 17117970.

Grucza, R. and Bierut, L. (2006).
Co-occurring risk factors for alcohol dependence and habitual smoking: Update on findings from the Collaborative Study on the Genetics of Alcoholism.
Alcohol Research & Health 29(3):172-178. PMID: 17373405. (pdf file)

Grucza, R., Cloninger, C.R., Bucholz, K., Constantino, J., Schuckit, M., Dick, D., and Bierut, L. (2006).
Novelty seeking as a moderator of familial risk for alcohol dependence.
Alcoholism: Clinical and Experimental Research 30(7):1176-1183. (pdf file)

Hayden, E.P., Wiegand, R.E., Meyer, E.T., Bauer, L.O., O'Connor, S.J., Nurnberger, J.I., Jr., Chorlian, D.B., Porjesz, B., and Begleiter, H. (2006).
Patterns of regional brain activity in alcohol-dependent subjects.
Alcoholism: Clinical and Experimental Research 30(12):1986-1991. (pdf file)

Helzer, J.E., Bucholz, K.K., Bierut, L.J., Regier, D.A., Schuckit, M.A., and Guth, S.E. (2006).
Should DSM-V include dimensional diagnostic criteria for alcohol use disorders?
Alcoholism: Clinical and Experimental Research 30(2):303-10. PMID: 16441279 (pdf file)

Hesselbrock, V. and Hesselbrock, M. (2006).
Are there empirically supported and clinically useful subtypes of alcohol dependence?
Addiction 101(Suppl 1):97-103. (pdf file)

Hesselbrock, V. and Hesselbrock, M. (2006).
Developmental perspectives on the risk for developing substance abuse problems.
In: Miller, W.R. & Carroll, K.M. (eds.), Rethinking substance abuse: What the science shows and what we should do about it.
Guilford Press, New York, 2006, pp. 97-114.

Hinrichs, A.L., Wang, J.C., Bufe, B., Kwon, J.M., Budde, J., Allen, R., Bertelsen, S., Evans, W., Dick, D., Rice, J., Foroud, T., Nurnberger, J., Tischfield, J.A., Kuperman, S., Crowe, R., Hesselbrock, V., Schuckit, M., Almasy, L., Porjesz, B., Edenberg, H.J., Begleiter, H., Meyerhof, W., Bierut, L.J., and Goate, A.M. (2006).
Functional variant in a bitter-taste receptor (hTAS2R16) influences risk of alcohol dependence.
American Journal of Human Genetics 78:103-111. (pdf file)

Johnson, C., Drgon, T., Liu, Q., Walther, D., Edenberg, H., Rice, J., Foroud, T., and Uhl, G. (2006).
Pooled association genome scanning for alcohol dependence using 104,268 SNPs: Validation and use to identify alcoholism vulnerability loci in unrelated individuals from the Collaborative Study on the Genetics of Alcoholism.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 141(8):844-853. (pdf file)

Jones, K.A., Porjesz, B., Chorlian, D., Rangaswamy, M., Kamarajan, C., Padmanabhapillai, A., Stimus, A., and Begleiter, H. (2006).
S-transform time-frequency analysis of P300 reveals deficits in individuals diagnosed with alcoholism.
Clinical Neurophysiology 117:2128-2143. (pdf file)

Jones, K.A., Porjesz, B., Almasy, L., Bierut, L., Goate, A., Hinrichs, A., Rice, J.P., Rohrbaugh, J., Bauer, L.O., Crowe, R.R., Edenberg, H.J., Foroud, T., Hesselbrock, V., Kuperman, S., Nurnberger, J., Jr., O'Connor, S.J., Schuckit, M.A., Tischfield, J.A., and Begleiter, H. (2006).
A cholinergic receptor gene (CHRM2) affects event-related oscillations.
Behavior Genetics 36:627-39. (pdf file)

Kamarajan, C., Porjesz, B., Jones, K., Chorlian, D., Padmanabhapillai, A., Rangaswamy, M., Stimus, A., and Begleiter, H. (2006).
Event-related oscillations in offspring of alcoholics: Neurocognitive disinhibition as a risk for alcoholism.
Biological Psychiatry 59:625-634. (pdf file)

Ohannessian, C., Hesselbrock, V., Ruddy, K., Kramer, J., Kuperman, S., Bucholz, K., and Schuckit, M. (2006).
The effects of parental substance use on adolescent psychological adjustment: A micro-level approach.
The Prevention Researcher 13(4):7-9.

Padmanabhapillai, A., Porjesz, B., Ranganathan, M., Jones, K.A., Chorlian, D.B., Tang, Y., Kamarajan, C., Rangaswamy, M., Stimus, A., and Begleiter, H. (2006).
Suppression of early evoked gamma band response in male alcoholics during a visual oddball task.
International Journal of Psychophysiology 60:15-26. (pdf file)

Padmanabhapillai, A., Tang, Y., Ranganathan, M., Rangaswamy, M., Jones, K.A., Chorlian, D.B., Kamarajan, C., Stimus, A.T., Kuperman, S., Rohrbaugh, J., O'Connor, S.J., Bauer, L.O., Schuckit, M.A., Begleiter, H., and Porjesz, B. (2006).
Evoked gamma band response in male adolescent subjects at high risk for alcoholism during a visual oddball task .
International Journal of Psychophysiology 62:262-271. (pdf file)

Schuckit, M., Windle, M., Smith, T., Hesselbrock, V., Ohannessian, C., Averna, S., Bauer, L., Kramer, J., Bucholz, K., and Sher, K. (2006).
Searching for the full picture: Structural equation modeling in alcohol research.
Alcoholism: Clinical and Experimental Research 30(2):194-202. (pdf file)

Volkow, N.D., Wang, G.-J., Begleiter, H., Porjesz, B., Fowler, J.S., Telang, F., Wong, C., Ma, Y., Logan, J.,Goldstein, R., Alexoff, B., and Thanos, P.K. (2006).
High levels of dopamine D2 receptors.
Archives of General Psychiatry 63:999-1006. (pdf file)

Wang, K., Porjesz, B., Jones, K., and Begleiter, H. (2006).
Genetic linkage and linkage disequilibrium analysis.
In: Chow, S.-C. (ed.), Encyclopedia of Biopharmaceutical Statistics
Taylor and Francis, New York, pp 1-12.

Xuei, X., Dick, D., Flury-Wetherill, L., Tian, H.-J., Agrawal, A., Bierut, L., Goate, A., Bucholz, K., Schuckit, M., Nurnberger, J.I., Jr., Tischfield, J., Kuperman, S., Porjesz, B., Begleiter, H., Foroud, T., and Edenberg, H.J. (2006).
Association of the κ-opioid system with alcohol dependence.
Molecular Psychiatry 11:1016-1024. (pdf file)

2005

Bailey-Wilson, J.E., Almasy, L., de Andrade, M., Bailey, J., Bickeböller, H., Cordell, H.J., Daw, E.W., Goldin, L., Goode, E.L., Gray-McGuire, C., Hening, W., Jarvik, G., Maher, B.S., Mendell, N., Paterson, A.D., Rice, J., Satten, G., Suarez, B., Vieland, V., Wilcox, M., Zhang. H., Ziegler, A., and MacCluer, J.W. (2005).
Genetic Analysis Workshop 14: Mirosatellite and single-nucleotide polymorphism marker loci for genome-wide scans.
BMC Genetics 6(Supplement 1):S1. (pdf file)

Ceballos, N., Houston, R., Smith, N., Bauer, L., and Taylor, R. (2005).
N400 as an index of semantic expectancies: Differential effects of alcohol and cocaine dependence.
Progress in Neuro-psychopharmacology & Biological Psychiatry 29:936-432. (pdf file)

Corbett, J., Saccone, N.L., Foroud, T., Goate, A., Edenberg, H., Nurnberger, J., Porjesz, B., Begleiter, H., Reich, T., and Rice, J.P. (2005).
A sex-adjusted and age-adjusted genome screen for nested alcohol dependence diagnoses.
Psychiatric Genetics 15:25-30. (pdf file)

Culverhouse, R., Bucholz, K.K., Crowe, R.R., Hesselbrock, V., Nurnberger, J., Jr., Porjesz, B., Schuckit, M.A., Reich, T., and Bierut, L.J. (2005).
Long-term stability of alcohol and other substance dependence diagnoses and habitual smoking: An evaluation after 5 years.
Archives of General Psychiatry 62:753-760. (pdf file)

Dick, D., Edenberg, H., Xuei, X., Goate, A., Hesselbrock, V., Schuckit, M., Crowe, R., and Foroud, T. (2005).
No association of the GABAA receptor genes on chromosome 5 with alcoholism in the Collaborative Study on the Genetics of Alcoholism sample.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 132(1):24-28. (pdf file)

Duncan, A.E., Neuman, R.J., Kramer, J., Kuperman, S., Hesselbrock, V., Reich, T., and Bucholz, K.K. (2005).
Are there subgroups of bulimia nervosa based on comorbid psychiatric disorders?
International Journal of Eating Disorders 37:19-25. (pdf file)

Dunn, G., Hinrichs, A., Bertelsen, S., Jin, C., Kauwe, J., Suarez, B., and Bierut, L. (2005).
Microsatellites versus single-nucleotide polymorphisms in linkage analysis for quantitative and qualitative measures.
BMC Genetics 6 (Suppl 1):S122. (pdf file)

Edenberg, H.J., Bierut, L.J., Boyce, P., Cao, M., Cawley, S., Chiles, R., Doheny, K.F., Hansen, M., Hinrichs, T., Jones, K., Kelleher, M., Kennedy, G.C., Liu, G., Marcus, G., McBride, C., Murray, S.S., Oliphant, A., Pettengill, J., Porjesz, B., Pugh, E.W., Rice, J.P., Rubano, T., Shannon, S., Steeke, R., Tischfield, J.A., Tsai, Y.Y., Zhang, C., and Begleiter, H. (2005).
Description of the data from the Collaborative Study on the Genetics of Alcoholism (COGA) and single-nucleotide polymorphism genotyping for Genetic Analysis Workshop 14.
BMC Genetics 6 (Supplement 1):S2. (pdf file)

Eng, M., Schuckit, M., and Smith, T. (2005).
The level of response to alcohol in daughters of alcoholics and controls.
Drug and Alcohol Dependence 79:83-93. (pdf file)

Hesselbrock, V., Higuchi, S., and Soyka, M. (2005).
Recent developments in the genetics of alcohol-related phenotypes.
Alcoholism: Clinical and Experimental Research 29(7):1321-1324. (pdf file)

Hinrichs, A., Bertelsen, S., Bierut, L., Dunn, G., Jin, C., Kauwe, J., and Suarez, B. (2005).
Multipoint identity-by-descent computations for single-point polymorphism and microsatellite maps.
BMC Genetics 6 (Suppl 1):S34. (pdf file)

Hinrichs, A. and Suarez, B. (2005).
Genotyping errors, pedigree errors, and missing data.
Genetic Epidemiology 29 (Suppl 1):S120-S124. (pdf file)

Kamarajan, C., Porjesz, B., Jones, K.A., Choi, K., Chorlian, D.B., Padmanabhapillai, A., Rangaswamy, M., Stimus, A.T., and Begleiter, H. (2005).
Alcoholism is a disinhibitory disorder: Neurophysiological evidence from a Go/No-Go task.
Biological Psychology 69:353-373. (pdf file)

Kamarajan, C., Porjesz, B., Jones, K.A., Chorlian, D.B., Padmanabhapillai, A., Rangaswamy, M., Stimus, A.T., and Begleiter, H. (2005).
Spatial-anatomical mapping of NoGo-P3 in the offspring of alcoholics: Evidence of cognitive and neural disinhibition as a risk for alcoholism.
Clinical Neurophysiology 116:1049-1061. (pdf file)

Kauwe, J., Bertelsen, S., Bierut, L., Dunn, G., Hinrichs, A., Jin, C., and Suarez, B. (2005).
The efficacy of short tandem repeat polymorphisms versus single-nucleotide polymorphisms for resolving population structure.
BMC Genetics 6 (Suppl 1):S84. (pdf file)

Kuperman, S., Chan, G., Kramer, J., Bierut, L., Bucholz, K., Fox, L., Hesselbrock, V., Nurnberger, J., Jr., Reich, T., Reich, W., and Schuckit, M. (2005).
Relationship of age of first drink to child behavioral problems and family psychopathology.
Alcoholism: Clinical and Experimental Research 29(10):1869-1876. (pdf file)

Ohannessian, C., Hesselbrock, V., Kramer, J., Kuperman, S., Bucholz, K., Schuckit, M., and Nurnberger, J., Jr. (2005).
The relationship between parental psychopatholgoy and adolescent psychopathology: An examination of gender patterns.
Journal of Emotional and Behavioral Disorders 13(2):67-76.

Porjesz, B., Rangaswamy, M., Kamarajan, C., Jones, K.A., Padmanabhapillai, A., and Begleiter, H. (2005).
The utility of neurophysiological markers in the study of alcoholism.
Clinical Neurophysiology 116:993-1018. (pdf file)

Rice, J. and Saccone, S. (2005).
Alcoholism and related traits: A summary of Group 13 contributions (GAW).
Genetic Epidemiology 29 (Suppl 1):S96-S102. (pdf file)

Saccone, S., Saccone, N., Neuman, R., and Rice, J. (2005).
Genetic analysis of the maximum drinks phenotype.
BMC Genetics 6 (Suppl 1):S124. (pdf file)

Schuckit, M.A., Smith, T.L., Danko, G., Anderson, K., Brown, S., Kuperman, S., Kramer, J., Hesselbrock, V., and Bucholz, K. (2005).
Evaluation of a level of response to alcohol based structural equation model in adolescents.
Journal of Studies on Alcohol and Drugs 66:174-184. (pdf file)

Schuckit, M.A., Smith, T.L., Danko, G., Kramer, J., Godinez, K., , Bucholz, K., Nurnberger, J., Jr., and Hesselbrock, V. (2005).
Prospective evaluation of the four DSM-IV criteria for alcohol abuse in a larger population.
American Journal of Psychiatry 162(2):350-360. (pdf file)

Schuckit, M.A., Smith, T.L., Danko, G., Kuperman, S., Bierut, L.J., and Hesselbrock, V. (2005).
Correlations among first-degree relatives for responses on the self-rating of the effects of alcohol (SRE) questionnaire in teenagers.
Journal of Studies on Alcohol and Drugs 66: 62-65. (pdf file)

Suarez, B., Taylor, C., Bertelsen, S., Bierut, L., Dunn, G., Jin, C., Kauwe, J., Paterson, A., and Hinrichs, A. (2005).
An analysis of identical single-nucleotide polymorphisms genotyped by two different platforms.
BMC Genetics 6 (Suppl 1):S152. (pdf file)

2004

Bierut, L.J., Rice, J.P., Goate, A., Hinrichs, A.L., Saccone, N.L., Foroud, T., Edenberg, H.J., Cloninger, C.R., Begleiter, H., Conneally, P.M., Crowe, R.R., Hesselbrock, V., Li, T.K., Nurnberger, J.I., Jr., Porjesz, B., Schuckit, M.A., and Reich, T. (2004).
A genomic scan for habitual smoking in families of alcoholics: Common and specific genetic factors in substance dependence.
American Journal of Medical Genetics 124A:19-27. (pdf file)

Dick, D.M., Edenberg, H.J., Xuei, X., Goate, A., Kuperman, S., Schuckit, M., Crowe, R., Smith, T.L., Porjesz, B., Begleiter, H., and Foroud, T. (2004).
Association of GABRG3 with alcohol dependence.
Alcoholism: Clinical and Experimental Research 28:4-9. (pdf file)

Dick, D.M., Li, T.K., Edenberg, H.J., Hesselbrock, V., Kramer, J., Kuperman, S., Porjesz, B., Bucholz, K., Goate, A., Nurnberger, J., and Foroud, T. (2004).
A genome-wide screen for genes influencing conduct disorder.
Molecular Psychiatry 9:81-86. (pdf file)

Edenberg, H.J., Dick, D.M., Xuei, X., Tian, H., Almasy, L., Bauer, L.O., Crowe, R.R., Goate, A., Hesselbrock, V., Jones, K., Kwon, J., Li, T.K., Nurnberger, J.I., Jr., O'Connor, S.J., Reich, T., Rice, J., Schuckit, M.A., Porjesz, B., Foroud, T., and Begleiter, H. (2004).
Variations in GABRA2, encoding the alpha 2 subunit of the GABAA receptor, are associated with alcohol dependence and with brain oscillations.
American Journal of Human Genetics 74:705-714. (pdf file)

Hesselbrock, V., Dick, D., Hesselbrock, M., Foroud, T., Schuckit, M., Edenberg, H., Bucholz, K., Kramer, J., Reich, T., Goate, A., Bierut, L., Rice, J., and Nurnberger, J.I., Jr. (2004).
The search for genetic risk factors associated with suicidal behavior.
Alcoholism: Clinical and Experimental Research 28(5):70S-76S.

Jones, K.A., Porjesz, B., Almasy, L., Bierut, L., Goate, A., Wang, J.C., Dick, D.M., Hinrichs, A., Kwon, J., Rice, J.P., Rohrbaugh, J., Stock, H., Wu, W., Bauer, L.O., Chorlian, D.B., Crowe, R.R., Edenberg, H.J., Foroud, T., Hesselbrock, V., Kuperman, S., Nurnberger Jr, J., O'Connor, S.J., Schuckit, M.A., Stimus, A.T., Tischfield, J.A., Reich, T., and Begleiter, H. (2004).
Linkage and linkage disequilibrium of evoked EEG oscillations with CHRM2 receptor gene polymorphisms: implications for human brain dynamics and cognition.
International Journal of Psychophysiology 53:75-90. (pdf file)

Kamarajan, C., Porjesz, B., Jones, K.A., Choi, K., Chorlian, D.B., Padmanabhapillai, A., Rangaswamy, M., Stimus, A.T., and Begleiter, H. (2004).
The role of brain oscillations as functional correlates of cognitive systems: A study of frontal inhibitory control in alcoholism.
International Journal of Psychophysiology 51:155-180. (pdf file)

Nurnberger, J.I., Jr., Wiegand, R., Bucholz, K., O'Connor, S., Meyer, E.T., Reich, T., Rice, J., Schuckit, M., King, L., Petti, T., Bierut, L., Hinrichs, A.L., Kuperman, S., Hesselbrock, V., and Porjesz, B. (2004).
A family study of alcohol dependence: Coaggregation of multiple disorders in relatives of alcohol-dependent probands.
Archives of General Psychiatry 61:1246-56. (pdf file)

Ohannessian, C., Hesselbrock, V., Kramer, J., Bucholz, K., Schuckit, M., Kuperman, S., and Nurnberger, J., Jr. (2004).

Parental substance use consequences and adolescent psychopathology.

Journal of Studies on Alcohol and Drugs 65(6):725-730. (pdf file)

Ohannessian, C., Hesselbrock, V., Kramer, J., Kuperman, S., Bucholz, K., Schuckit, M., and Nurnberger, J., Jr. (2004).
The relationship between parental alcoholism and adolescent psychopathology: A systematic examination of parental comorbid psychopathology.
Journal of Abnormal Child Psychology 32(5):519-533. (pdf file)

Polich, J. and Ochoa, C.J. (2004).
Alcoholism risk, tobacco smoking, and P300 event-related potential.
Clinical Neurophysiology 115:1374-1383. (pdf file)

Porjesz, B., Jones, K., and Begleiter, H. (2004).
The genetics of oscillations in the human brain.
In: Hallett, M., Phillips II, L.H., Schomer, D.L., Massey, J.M. (Eds.), Advances in Clinical Neurophysiology (Supplements to Clinical Neurophysiology, Volume 57).
Elsevier, B.V., The Netherlands, pp 437-445. (pdf file)

Rangaswamy, M., Porjesz, B., Ardekani, B.A., Choi, S.J., Tanabe, J.L., Lim, K.O., and Begleiter, H. (2004).
A functional MRI study of visual oddball: Evidence for frontoparietal dysfunction in subjects at risk for alcoholism.
Neuroimage 21:329-339. (pdf file)

Rangaswamy, M., Porjesz, B., Chorlian, D.B., Wang, K., Jones, K.A., Kuperman, S., Rohrbaugh, J., O'Connor, S.J., Bauer, L.O., Reich, T., and Begleiter, H. (2004).
Resting EEG in offspring of male alcoholics: Beta frequencies.
International Journal of Psychophysiology 51:239-251. (pdf file)

Stassen, H.H., Begleiter, H., Beirut, L., Culverhouse, R., Hinrichs, T., Porjesz, B., Rice, J., Scharfetter, C., and Reich, T. (2004).
Oligogenic approaches to the predisposition of alcohol dependence. A genome-wide search on 255 families.
Neurology, Psychiatry and Brain Research 11: 13-22. (pdf file)

Wang, J.C., Hinrichs, A.L., Stock, H., Budde, J., Allen, R., Bertelsen, S., Kwon, J.M., Wu, W., Dick, D.M., Rice, J., Jones, K., Nurnberger, J.I., Jr., Tischfield, J., Porjesz, B., Edenberg, H.J., Hesselbrock, V., Crowe, R., Schuckit, M., Begleiter, H., Reich, T., Goate, A.M., and Bierut, L.J. (2004).
Evidence of common and specific genetic effects: association of the muscarinic acetylcholine receptor M2 (CHRM2) gene with alcohol dependence and major depressive syndrome.
Human Molecular Genetics 13:1903-1911. (pdf file)

2003

Almasy, L. (2003).
Quantitative risk factors as indices of alcoholism susceptibility.
Annals of Medicine 35:337-343. (pdf file)

Chorlian, D.B., Porjesz, B., and Begleiter, H. (2003).
Determination of human EEG alpha entrainment ERD/ERS using the continuous complex wavelet transform.
Proceedings of SPIE 5102:145-55. (pdf file)

Dick, D.M. and Foroud, T. (2003).
Candidate genes for alcohol dependence: A review of genetic evidence from human studies.
Alcoholism: Clinical and Experimental Research 27(5):868-879. (pdf file)

Foroud, T. and Nurnberger, J., Jr. (2003).

Genetics of addictive disorders.

In: Soares, J. and Gershon, S. (eds.), The Handbook of Medical Psychiatry, Series Volume 20.

Marcel Dekker, Inc., New York.

Ghosh, S., Begleiter, H., Porjesz, B., Chorlian, D.B., Edenberg, H.J., Foroud, T., Goate, A., and Reich, T. (2003).
Linkage mapping of beta 2 EEG waves via non-parametric regression.
American Journal of Medical Genetics 118B:66-71. (pdf file)

Hesselbrock, M.N., Hesselbrock, V.M., Segal, B., Schuckit, M.A., and Bucholz, K. (2003).
Ethnicity and psychiatric co-morbidity among alcohol dependent persons who receive inpatient treatment: African Americans, Alaska Natives & Caucasians and Hispanics.
Alcoholism: Clinical and Experimental Research 27(8): 1368-1373. (pdf file)

Hesselbrock, V.M., Hesselbrock, M.N., and Segal, B. (2003).
Alcohol dependence among Alaskan Natives and their health care utilization.
Alcoholism: Clinical and Experimental Research 27(8): 1353-1355. (pdf file)

Porjesz, B. and Begleiter, H. (2003).
Alcoholism and human electrophysiology.
Alcohol Research & Health 27:153-160. (pdf file)

Preuss, U.W., Schuckit, M.A., Smith, T.L., Danko, G.P., Bucholz, K.K., Hesselbrock, M.N., Hesselbrock, V., and Kramer, J.R. (2003).
Predictors and correlates of suicide attempts over 5 years in 1,237 alcohol-dependent men and women.
American Journal of Psychiatry 160:56-63. (pdf file)

Rangaswamy, M., Porjesz, B., Chorlian, D.B., Choi, K., Jones, K.A., Wang, K., Rohrbaugh, J., O'Connor, S., Kuperman, S., Reich, T., and Begleiter, H. (2003).
Theta power in the EEG of alcoholics.
Alcoholism: Clinical and Experimental Research 27:607-615. (pdf file)

Rice, J.P., Neuman, R.J., Saccone, N.L., Corbett, J., Rochberg, N., Hesselbrock, V., Bucholz, K.K., McGuffin, P., and Reich, T. (2003).
Age and birth cohort effects on rates of alcohol dependence.
Alcoholism: Clinical and Experimental Research 27(1):93-99. (pdf file)

Rice, J.P., Saccone, N.L., Foroud, T., Edenberg, H.J., Nurnberger, J,I,, Jr., Goate, A., Crowe, R.R., Hesselbrock, V., Schuckit, M., Porjesz, B., Reich, T., and Begleiter, H. (2003).
Alcoholism: The USA Collaborative Study on the Genetics of Alcoholism (COGA).
In: Cooper, D.N. (ed.), Encyclopedia of the Human Genome.
Macmillian Publishers Ltd., Nature Publishing Group.

Schuckit, M., Danko, G., Smith, T., Hesselbrock, V., Kramer, J., and Bucholz, K. (2003).
A five-year prospective evaluation of DSM-IV alcohol dependence with and without a physiological component.
Alcoholism: Clinical and Experimental Research 27:818-825.

Song, J., Koller, D.L., Foroud, T., Carr, K., Zhao, J., Rice, J., Nurnberger, J.I., Jr., Begleiter, H., Porjesz, B., Smith, T.L., Schuckit, M.A., and Edenberg, H.J. (2003).
Association of GABAA receptors and alcohol dependence and the effects of genetic imprinting.
American Journal of Medical Genetics, Part B, Neuropsychiatric Genetics 117B:39-45. (pdf file)

Suresh, S., Porjesz, B., Chorlian, D.B., Choi, K., Jones, K.A., Wang, K., Stimus, A., and Begleiter, H. (2003).
Auditory P3 in Female Alcoholics.
Alcoholism: Clinical and Experimental Research 27:1064-1074. (pdf file)

Wilhelmsen, K.C., Schuckit, M., Smith, T.L., Lee, J.V., Segall, S.K., Feiler, H.S., and Kalmijn, J. (2003).
A search for genes related to a low-level response to alcohol as established by an alcohol challenge.
Alcoholism: Clinical and Experimental Research 27(7):1041-1047. (pdf file)

2002

Ardekani, B.A., Choi, S.J., Hossein-Zadeh, G.A., Porjesz, B., Tanabe, J.L., Lim, K.O., Bilder, R., Helpern, J.A., and Begleiter, H. (2002).
Functional magnetic resonance imaging of brain activity in the visual oddball task.
Cognitive Brain Research 14:347-356. (pdf file)

Bierut, L.J., Saccone, N.L., Rice, J.P., Goate, A., Foroud, T., Edenberg, H., Almasy, L., Conneally, P.M., Crowe, R., Hesselbrock, V., Li, T.-K., Nurnberger, J., Jr., Porjesz, B., Schuckit, M.A., Tischfield, J., Begleiter, H., and Reich, T. (2002).
Defining alcohol-related phenotypes in humans. The Collaborative Study on the Genetics of Alcoholism.
Alcohol Research & Health 26:208-213. (pdf file)

Cohen, H.L., Ji, J., Chorlian, D.B., Begleiter, H., and Porjesz, B. (2002).
Alcohol-related ERP changes recorded from different modalities: A topographic analysis.
Alcoholism: Clinical and Experimental Research 26:303-317. (pdf file)

Dick, D.M. and Foroud, T. (2002).
Genetic strategies to detect genes involved in alcoholism and alcohol-related traits.
Alcohol Research & Health 26(3):172-180.

Dick, D.M., Nurnberger, J., Jr., Edenberg, H.J., Goate, A., Crowe, R., Rice, J., Bucholz, K.K., Kramer, J., Schuckit, M.A., Smith, T.L., Porjesz, B., Begleiter, H., Hesselbrock, V., and Foroud, T. (2002).
Suggestive linkage on chromosome 1 for a quantitative alcohol-related phenotype.
Alcoholism: Clinical and Experimental Research 26:1453-1460. (pdf file)

Edenberg, H.J. (2002).
The Collaborative Study on the Genetics of Alcoholism: An update.
Alcohol Research & Health 26(3):214-218.

Foroud, T., Berrettini, W.H. (2002).
Addictive Disorders.
In: Principles and Practice of Medical Genetics, Editors: Rimoin, D.L., Connor, J.M., Pyeritz, R.E. and Korf, B.R.

Churchill Livingstone, 4th Ed. London: Harcourt Brace, pp 2949-2971.

Hesselbrock, V. and Mitsuru, K. (2002).
COGA.
Bunshi-Seishin Igaku Journal of Molecular Psychiatry 2:1.

Jones, K., Begleiter, H., Porjesz, B., Wang, K., and Chorlian, D. (2002).
Complexity measures of event related potential surface Laplacian data calculated using the wavelet packet transform.
Brain Topography 14:333-344. (pdf file)

Nurnberger, J.I., Jr., Foroud, T., Flury, L., Meyer, E.T., and Wiegand, R. (2002).
Is there a genetic relationship between alcoholism and depression?
Alcohol Research & Health 26(3):233-240.

Porjesz, B., Almasy, L., Edenberg, H.J., Wang, K., Chorlian, D.B., Foroud, T., Goate, A., Rice, J.P., O'Connor, S.J., Rohrbaugh, J., Kuperman, S., Bauer, L.O., Crowe, R.R., Schuckit, M.A., Hesselbrock, V., Conneally, P.M., Tischfield, J.A., Li, T.-K., Reich, T., and Begleiter, H. (2002).
Linkage disequilibrium between the beta frequency of the human EEG and a GABAA receptor gene locus.
Proceedings of the National Academy of Sciences of the United States of America 99:3729-3733. (pdf file)

Porjesz, B., Begleiter, H., Wang, K., Almasy, L., Chorlian, D.B., Stimus, A.T., Kuperman, S., O'Connor, S.J., Rohrbaugh, J., Bauer, L.O., Edenberg, H.J., Goate, A., Rice, J.P., and Reich, T. (2002).
Linkage and linkage disequilibrium mapping of ERP and EEG phenotypes.
Biological Psychology 61:229-248. (pdf file)

Preuss, U.W., Schuckit, M.A., Smith, T.L., Danko, G.P., Buckman, K., Bierut, L., Bucholz, K.K., Hesselbrock, M.N., Hesselbrock, V.M., and Reich, T. (2002).
Comparison of 3190 alcohol-dependent individuals with and without suicide attempts.
Alcoholism: Clinical and Experimental Research 26(4):471-477.

Preuss, U.W., Schuckit, M.A., Smith, T.L., Danko, G.P., Dasher, A.C., Hesselbrock, M.N., Hesselbrock, V.M., and Nurnberger, J.I., Jr. (2002).
A comparison of alcohol-induced and independent depression in alcoholics with histories of suicide attempts.
Journal of Studies on Alcoholism 63:498-502.

Rangaswamy, M., Porjesz, B., Chorlian, D.B., Wang, K., Jones, K.A., Bauer, L.O., Rohrbaugh, J., O'Connor, S.J., Kuperman, S., Reich, T., and Begleiter, H. (2002).
Beta power in the EEG of alcoholics.
Biological Psychiatry 52:831-842. (pdf file)

Saccone, N.L., Rice, J.P., Rochberg, N., Williams, J.T., Goate, A., Reich, T., Edenberg, H.J., Foroud, T., Nurnberger, J.I., Jr., Bierut, L.J., Crowe, R., and Li, T.-K. (2002).
Linkage for platelet monomine oxidase (MAO) activity: Results from a replication sample.
Alcoholism: Clinical and Experimental Research 26(5):603-609. (pdf file)

Schuckit, M.A., Danko, G.P., Smith, T.L., and Buckman, K.R. (2002).
The five-year predictive validity of each of the seven DSM-IV items for alcohol dependence among alcoholics.
Alcoholism: Clinical and Experimental Research 26(7):980-987. (pdf file)

Schuckit, M.A., Smith, T.L., Danko, G.P., Reich, T., Bucholz, K.K., and Bierut, L.J. (2002).
Similarities in the clinical characteristics related to alcohol dependence in two populations.
American Journal of Addictions 11:1-9.

Schuckit, M.A., Smith, T.L., Kramer, J., Danko, G., and Volpe, F.R. (2002).
The prevalence and clinical course of sedative-hypnotic abuse and dependence in a large cohort.
American Journal of Drug and Alcohol Abuse 28(1):73-90.

2001

Almasy, L., Porjesz, B., Blangero, J., Goate, A., Edenberg, H.J., Chorlian, D.B., Kuperman, S., O'Connor, S.J., Rohrbaugh, J., Bauer, L.O., Foroud, T., Rice, J.P., Reich, T., and Begleiter, H. (2001).
Genetics of event-related brain potentials in response to a semantic priming paradigm in families with a history of alcoholism.
American Journal of Human Genetics 68:128-135. (pdf file)

Daw, E.W., Rice, J.P., Anthenelli, R.M., Schuckit, M.A., Tipp, J., Saccone, N.L., Reich, T., Nurnberger, J.I., Jr., and Li, T.-K. (2001).
A bootstrapped commingling analysis of platelet monoamine oxidase activity levels corrected of cigarette smoking.
Psychiatric Genetics 11(4):177-185.

Dick, D., Nurnberger, J., Jr., Edenberg, H., Goate, A., Crowe, R., Rice, J., Hesselbrock, V., and Foroud, T. (2001).
Suggestive linkage on chromosomes 1 and 15 for a protective alcohol-related phenotype.
American Journal of Human Genetics 69(4) Suppl:530 (#2042).

Hada, M., Porjesz, B., Chorlian, D.B., Begleiter, H., and Polich, J. (2001).
Auditory P3a deficits in male subjects at high risk for alcoholism.
Biological Psychiatry 49:726-738. (pdf file)

Hesselbrock, V., Begleiter, H., Porjesz, B., O'Connor, S., and Bauer, L. (2001).
P300 event-related potential amplitude as an endophenotype of alcoholism-evidence from the collaborative study on the genetics of alcoholism.
Journal of Biomedical Science 8:77-82. (pdf file)

Hesselbrock, V.M., Foroud, T., Edenberg, H., Nurnberger, J.I., Jr., Reich, T., and Rice, J.P. (2001).
Genetics and alcoholism: The COGA project.
In: Alcohol in Health and Disease, Editors: Agaarwal, D.P. and Seitz, H.K.
Marcel Dekker, Inc., New York, pp 103-124.

Kuperman, S., Schlosser, S.S., Kramer, J.R., Bucholz, K., Hesselbrock, V., Reich, T., and Reich, W. (2001).
Developmental sequence from disruptive behavior diagnosis to adolescent alcohol dependence.
American Journal of Psychiatry 158:2022-2026.

Kuperman, S., Schlosser, S.S., Kramer, J.R., Bucholz, K., Hesselbrock, V., Reich, T., and Reich, W. (2001).
Risk domains associated with an adolescent alcohol dependence diagnosis.
Addiction 96:629-636. (pdf file)

Nurnberger, J.I., Jr., Foroud, T., Flury, L., Su, J., Meyer, E.T., Hu, K., Crowe, R., Edenberg, H., Goate, A., Bierut, L., Reich, T., Schuckit, M., and Reich, W. (2001).
Evidence for a locus on chromosome 1 that influences vulnerability to alcoholism and affective disorder.
American Journal of Psychiatry 158:718-724. (pdf file)

Prabhu, V.R., Porjesz, B., Chorlian, D.B., Wang, K., Stimus, A., and Begleiter, H. (2001).
Visual P3 in female alcoholics.
Alcoholism: Clinical and Experimental Research 25:531-539. (pdf file)

Schuckit, M., Danko, G.P., Raimo, E.B., Smith, T.L., Eng, M.Y., Carpenter, K.K.T., and Hesselbrock, V.M. (2001).
A preliminary evaluation of the potential usefulness of the diagnoses of polysubstance dependence.
Journal of Studies on Alcoholism 62:54-61.

Schuckit, M.A., Edenberg, H.J., Kalmijn, J., Flury, L., Smith, T.L., Reich, T., Bierut, L., Goate, A., and Foroud, T. (2001).
A genome-wide search for genes that relate to a low level of response to alcohol.
Alcoholism: Clinical and Experimental Research 25(3):323-329. (pdf file)

Schuckit, M.A., Smith, T.L., Danko, G.P., Bucholz, K.K., Reich, T., and Bierut, L. (2001).
Five-year clinical course associated with DSM-IV alcohol abuse or dependence in a large group of men and women.
American Journal of Psychiatry 158(7):1084-1090. (pdf file)

Vedeniapin, A.B., Anokhin, A.P., Sirevaag, E., Rohrbaugh, J.W., and Cloninger, C.R. (2001).
Visual P300 and the self-directed scale of the temperament and character inventory.
Psychiatry Research 101:145-156.

Wang, K., Begleiter, H., and Porjesz, B. (2001).
Warp-averaging event-related potentials.
Clinical Neurophysiology 112:1917-1924. (pdf file)

Zhang, X.L., Cohen, H.L., Porjesz, B., and Begleiter, H. (2001).
Mismatch negativity in subjects at high risk for alcoholism.
Alcoholism: Clinical and Experimental Research 25:330-337. (pdf file)

2000

Anokhin, A.P., Vedeniapin, A.B., Sirevaag, E.J., Bauer, L.O., O'Connor, S.J., Kuperman, S., Porjesz, B., Reich, T., Begleiter, H., Polich, J., and Rohrbaugh, J.W. (2000).
The P300 brain potential is reduced in smokers.
Psychopharmacology 149:409-413. (pdf file)

Begleiter, H. and Porjesz, B. (2000).
What is inherited in the predisposition to alcoholism: New model or more muddle?.
Alcoholism: Clinical and Experimental Research 24:246-250. (pdf file)

Bierut, L.J., Rice, J.P., Edenberg, H.J., Goate, A., Foroud, T., Cloninger, C.R., Begleiter, H., Conneally, P.M., Crowe, R.R., Hesselbrock, V., Li, T.K., Nurnberger, J.I., Jr., Porjesz, B., Schuckit, M.A., and Reich, T. (2000).
Family-based study of the association of the dopamine D2 receptor gene (DRD2) with habitual smoking.
American Journal of Medical Genetics 90:299-302. (pdf file)

Bierut, L.J., Schuckit, M.A., Hesselbrock, V., Reich, T. (2000).
Co-occurring risk factors for alcohol dependence and habitual smoking. Results from the Collaborative Study on the Genetics of Alcoholism.
Alcohol Health & Research World 24(4):233-241.

Bucholz, K., Hesselbrock, V., Heath, A., Kramer, J., and Schuckit, M. (2000).
A latent class analysis of antisocial personality disorder symptom data from a multi-centre family study of alcoholism.
Addiction 95(4):553-567. (pdf file)

Costa, L., Bauer, L., Kuperman, S., Porjesz, B., O'Connor, S., Hesselbrock, V., Rohrbaugh, J., and Begleiter, H. (2000).
Frontal P300 decrements, alcohol dependence, and antisocial personality disorder.
Biological Psychiatry 47:1064-1071. (pdf file)

Daeppen, J.B., Smith, T., Danko, G., Gordon, L., Landi, N., Nurnberger, J.I., Jr., Bucholz, K., Raimo, E., and Schuckit, M. (2000).
Clinical correlates of cigarette smoking and nicotine dependence in alcohol dependent men and women.
Alcohol 35(2):171-175.

Foroud, T., Edenberg, H.J., Goate, A., Rice, J., Flury, L., Koller, D.L., Bierut, L.J., Conneally, P.M., Nurnberger, J.I., Bucholz, K.K., Li, T.-K., Hesselbrock, V., Crowe, R., Schuckit, M., Porjesz, B., Begleiter, H., and Reich, T. (2000).
Alcoholism susceptibility loci: Confirmation studies in a replicate sample and further mapping.
Alcoholism: Clinical and Experimental Research 24:933-945. (pdf file)

Hada, M., Porjesz, B., Begleiter, H., and Polich, J. (2000).
Auditory P3a assessment of male alcoholics.
Biological Psychiatry 48:276-286. (pdf file)

Hesselbrock, V., Hesselbrock, M., Bucholz, K., Schuckit, M., Begleiter, H., Porjesz, B., Nurnberger, J., Jr., and Reich, T. (2000).
A five cluster phenotype of alcohol dependence.
Alcoholism: Clinical and Experimental Research 24(5):163A.

McClintick, J. and Edenberg, H.J. (2000).
BlastReport: A Perl script to facilitate the use of sequence databases for mapping and clustering.
Biotechniques 29(6):1272-1276.

Raimo, E.B., Smith, T.L., Danko, G.P., Bucholz, K.K., and Schuckit, M.A. (2000).
Clinical characteristics and family histories of alcoholics with stimulant dependence.
Journal of Studies on Alcoholism 61:728-735.

Saccone, N.L., Kwon, J.M., Corbett, J., Goate, A., Rochberg, N., Edenberg, H.J., Foroud, T., Li, T.-K., Begleiter, H., Reich, T., and Rice, J.P. (2000).
A genome screen of maximum number of drinks as an alcoholism phenotype.
American Journal of Medical Genetics 96:632-637. (pdf file)

Schuckit, M.A., Smith, T.L., Kalmijn, J., Tsuang, J., Hesselbrock, V., and Bucholz, K.K. (2000).
Response to alcohol in daughters of alcoholics: A pilot study and a comparison with sons of alcoholics.
Alcohol 35(3):242-248.

Wang, K., Begleiter, H., and Porjesz, B. (2000).
Trilinear modeling of event-related potentials.
Brain Topography 12:263-271. (pdf file)

1999

Almasy, L. and Borecki, I.B. (1999)
Exploring genetic analysis of complex traits through the paradigm of alcohol dependence: summary of GAW11 contributions.
Genetic Epidemiololgy 17(Suppl. 1):S1-24. PMID: 10597406

Almasy, L., Porjesz, B., Blangero, J., Chorlian, D.B., O'Connor, S.J., Kuperman, S., Rohrbaugh, J., Bauer, L.O., Reich, T., Polich, J., and Begleiter, H. (1999).
Heritability of event-related brain potentials in families with a history of alcoholism.
American Journal of Medical Genetics 88:383-390. (pdf file)

Begleiter, H. and Porjesz, B. (1999).
What is inherited in the predisposition toward alcoholism? A proposed model.
Alcoholism: Clinical and Experimental Research 23:1125-1135. (pdf file)

Begleiter, H., Reich, T., Nurnberger, J., Jr., Li, T.-K., Conneally, P.M., Edenberg, H., Crowe, R., Kuperman, S., Schuckit, M., Bloom, F., Hesselbrock, V., Porjesz, B., Cloninger, C.R., Rice, J., and Goate, A. (1999).
Description of the genetic analysis workshop 11 Collaborative Study on the Genetics of Alcoholism.
Genetic Epidemiology 17 (Supplement 1):S25-S30. (pdf file)

Foroud, T. and Li, T.-K. (1999).
Genetics of alcoholism: A review of recent studies in human and animal models.
The American Journal on Addictions 8:261-278.

Hesselbrock, M., Easton, C., Bucholz, K., Schuckit, M., Hesselbrock, V.A. (1999).
Validity study of the SSAGA - a comparison with the SCAN.
Addiction 94(9):1361-1370. (pdf file)

Holguin, S.R., Porjesz, B., Chorlian, D.B., Polich, J., and Begleiter, H. (1999).
Visual P3a in male subjects at high risk for alcoholism.
Biological Psychiatry 46:281-291. (pdf file)

Holguin, S.R., Porjesz, B., Chorlian, D.B., Polich, J., and Begleiter, H. (1999).
Visual P3a in male alcoholics and controls.
Alcoholism: Clinical and Experimental Research 23:582-591. (pdf file)

Kuperman, S., Schlosser, S., Lidral, J., and Reich, W. (1999).
Relationship of child psychopathology to parental alcoholism and ASPD.
Journal of the American Academy of Child and Adolescent Psychiatry 38(6):686-692. PMID: 10361786 (pdf file)

Neuman, R.J., Todd, R.D., Heath, A.C., Reich, W., Hudziak, J.J., Bucholz, K.K., Madden, P.A., Begleiter, H., Porjesz, B., Kuperman, S., Hesselbrock, V., and Reich, T. (1999).
Evaluation of ADHD typology in three contrasting samples: A latent class approach.
Journal of the American Academy of Child and Adolescent Psychiatry 38:25-33. (pdf file)

Polich, J. and Bloom, F. (1999).
P300, alcoholism inheritability, and stimulus modality.
Alcohol 17:149-156. (pdf file)

Raimo, E.B., Daeppen, J.B., Smith, T.L., Danko, G.P., and Schuckit, M.A. (1999).
Clinical characteristics of alcoholism in alcohol-dependent subjects with and without history of alcohol treatment.
Alcoholism: Clinical and Experimental Research 23(10):1605-1613.

Reich, T., Hinrichs, A., Culverhouse, R., and Bierut, L. (1999).
Psychiatric genetics '99 - genetic studies of alcoholism and substance dependence.
The American Journal of Human Genetics 65:599-605.

Saccone, N.L., Rice, J.P., Rochberg, N., Goate, A., Reich, T., Shears, S., Wu, W., Nurnberger, J.I., Jr., Foroud, T., Edenberg, H.J., and Li, T.-K. (1999).
A genome screen for platelet monoamine oxidase (MAO) activity.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 88:517-521.

Schuckit, M. (1999).
New findings in the genetics of alcoholism.
The Journal of the American Medical Association 281(20):1875-1876.

Schuckit, M.A., Daeppen, J.-B., Danko, G.P., Tripp, M.L., Smith, T.L., Li, T.-K., Hesselbrock, V.M., and Bucholz, K.K. (1999).
Clinical implications for four drugs of the DSM-IV distinction between substance dependence with and without a physiological component.
The American Journal of Psychiatry 156(1):41-49. (pdf file)

Stassen, H.H., Begleiter, H., Porjesz, B., Rice, J., Scharfetter, C., and Reich, T. (1999).
Structural decomposition of genetic diversity in families with alcoholism.
Genetic Epidemiology 17 (Supplement 1):S325-330. (pdf file)

Williams, J.T., Begleiter, H., Porjesz, B., Edenberg, H.J., Foroud, T., Reich, T., Goate, A., Van Eerdewegh, P., Almasy, L., and Blangero, J. (1999).
Joint multipoint linkage analysis of multivariate qualitative and quantitative traits. II. Alcoholism and event-related potentials.
American Journal of Human Genetics 65:1148-1160. (pdf file)

1998

Almasy, L., Williams, J., Porjesz, B., Reich, T., Blangero, J., and Begleiter, H. (1998).
Pleiotropic genetic influences on event-related brain potentials and alcoholism.
American Journal of Medical Genetics 81:495-496.

Anokhin, A. and Rohrbaugh, J. (1998).
Frontal EEG asymmetry in families.
Psychophysiology (Supplement) 35:517.

Anthenelli, R.M., Tipp, J., Li, T.-K., Magnes, L., Schuckit, M.A., Rice, J., Daw, W., and Nurnberger, J., Jr. (1998).
Platelet monoamine oxidase activity in subgroups of alcoholics and controls: Results from the Collaborative Study on the Genetics of Alcoholism.
Alcoholism: Clinical and Experimental Research 22(3):598-604.

Begleiter, H., Porjesz, B., Reich, T., Edenberg, H.J., Goate, A., Blangero, J., Almasy, L., Foroud, T., Van Eerdewegh, P., Polich, J., Rohrbaugh, J., Kuperman, S., Bauer, L.O., O'Connor, S.J., Chorlian, D.B., Li, T.K., Conneally, P.M., Hesselbrock, V., Rice, J.P., Schuckit, M.A., Cloninger, R., Nurnberger, J., Jr., Crowe, R., and Bloom, F.E. (1998).
Quantitative trait loci analysis of human event-related brain potentials: P3 voltage.
Electroencephalography and Clinical Neurophysiology 108:244-250. (pdf file)

Bierut, L.J., Dinwiddie, S.H., Begleiter, H., Crowe, R.R., Hesselbrock, V., Nurnberger, J.I., Jr., Porjesz, B., Schuckit, M.A., and Reich, T. (1998).
Familial transmission of substance dependence: Alcohol, marijuana, cocaine, and habitual smoking: A report from the Collaborative Study on the Genetics of Alcoholism.
Archives of General Psychiatry 55:982-988. (pdf file)

Blangero, J. (1998).
Quantitative trait locus mapping methods for complex phenotypes: The state-of-the-science.
American Journal of Medical Genetics 81:461.

Cloniger, C.R., Van Eerdewegh, P., Goate, A., Edenberg, H.J., Blangero, J., Hesselbrock, V., Reich, T., Nurnberger, J.I., Schuckit, M., Porjesz, B., Crowe, R., Rice, J.P., Foroud, T., Przybeck, T.R., Almasy, L., Buchholz, K., Wu, W., Shears, S., Carr, K., Crose, C., Willig, C., Zhou, J., Tischfield, J.A., Li, T.-K., Conneally, P.M., and Begleiter, H. (1998).
Anxiety proneness linked to epistatic loci in genome scan of human personality traits.
American Journal of Medical Genetics 81:313-317. (pdf file)

Edenberg, H.J., Foroud, T., Koller, D.L., Goate, A., Rice, J., Van Eerdewegh, P., Reich, T., Cloninger, C.R., Nurnberger, J.I., Jr., Kowalczuk, M., Wu, B., Li, T.K., Conneally, P.M., Tischfield, J.A., Wu, W., Shears, S., Crowe, R., Hesselbrock, V., Schuckit, M., Porjesz, B., and Begleiter, H. (1998).
A family-based analysis of the association of the dopamine D2 receptor (DRD2) with alcoholism.
Alcoholism: Clinical and Experimental Research 22:505-512. (pdf file)

Edenberg, H.J., Foroud, T., Koller, D.L., Goate, A., Rice, J., Van Eerdewegh, P., Reich, T., Cloninger, C.R., Nurnberger, J.I., Jr., Kowalczuk, M., Wu, B., Li, T.K., Conneally, P.M., Tischfield, J.A., Wu, W., Shears, S., Crowe, R., Hesselbrock, V., Schuckit, M., Porjesz, B., and Begleiter, H. (1998).
Letter to the editor, Science, in response to previously published letter to the editor by Dr. Ernest Noble, re: A family-based analysis of the association of the dopamine D2 receptor (DRD2) with alcoholism.
Science 282:1265. (pdf file)

Edenberg, H., Reich, T., Foroud, T., Goate, A., Rice, J., and Begleiter, H. (1998).
Genes affecting alcohol dependence and related phenotypes: A genomic survey by the Collaborative Study on the Genetics of Alcoholism (COGA).
Miami Nature Biology Short Reports 9:71-72.

Edenberg, H. and Reynolds, J. (1998).
Improved method for detecting the long and short promoter alleles of the serotonin transporter gene HTT (SLC6A4).
Psychiatric Genetics 8:193-195.

Edenberg, H.J., Reynolds, J., Koller, D.L., Begleiter, H., Bucholz, K.K., Conneally, P.M., Crowe, R., Goate, A., Hesselbrock, V., Li, T.K., Nurnberger, J.I., Jr., Porjesz, B., Reich, T., Rice, J.P., Schuckit, M., Tischfield, J.A., and Foroud, T. (1998).
A family-based analysis of whether the functional promoter alleles of the serotonin transporter gene HTT affect the risk for alcohol dependence.
Alcoholism: Clinical and Experimental Research 22:1080-1085. (pdf file)

Foroud, T., Bucholz, K.K., Edenberg, H.J., Goate, A., Neuman, R.J., Porjesz, B., Koller, D.L., Rice, J., Reich, T., Bierut, L.J., Cloninger, C.R., Nurnberger, J.I., Jr., Li, T.K., Conneally, P.M., Tischfield, J.A., Crowe, R., Hesselbrock, V., Schuckit, M., and Begleiter, H. (1998).
Linkage of an alcoholism-related severity phenotype to chromosome 16.
Alcoholism: Clinical and Experimental Research 22:2035-2042. (pdf file)

Goate, A. and Edenberg, H. (1998).
The genetics of alcoholism.
In: Current Opinion in Genetics and Development (Eds. Davies, K. and Willard, H.) 8:282-286.

Porjesz, B. and Begleiter, H. (1998).
Genetic basis of event-related potentials and their relationship to alcoholism and alcohol use.
Journal of Clinical Neurophysiology 15:44-57. (pdf file)

Porjesz, B., Begleiter, H., Reich, T., Van Eerdewegh, P., Edenberg, H.J., Foroud, T., Goate, A., Litke, A., Chorlian, D.B., Stimus, A., Rice, J., Blangero, J., Almasy, L., Sorbell, J., Bauer, L.O., Kuperman, S., O'Connor, S.J., and Rohrbaugh, J. (1998).
Amplitude of visual P3 event-related potential as a phenotypic marker for a predisposition to alcoholism: Preliminary results from the COGA Project. Collaborative Study on the Genetics of Alcoholism.
Alcoholism: Clinical and Experimental Research 22:1317-1323. (pdf file)

Reich, T., Edenberg, H.J., Goate, A., Williams, J.T., Rice, J.P., Van Eerdewegh, P., Foroud, T., Hesselbrock, V., Schuckit, M.A., Bucholz, K., Porjesz, B., Li, T.K., Conneally, P.M., Nurnberger, J.I., Jr., Tischfield, J.A., Crowe, R.R., Cloninger, C.R., Wu, W., Shears, S., Carr, K., Crose, C., Willig, C., and Begleiter, H. (1998).
Genome-wide search for genes affecting the risk for alcohol dependence.
American Journal of Medical Genetics 81:207-215. (pdf file)

Schuckit, M., Daeppen, J.-B., Tipp, J., Hesselbrock, M., and Bucholz, K. (1998).
The clinical course of alcohol-related problems in alcohol dependent and nonalcohol dependent drinking women and men.
Journal of Studies on Alcohol and Drugs 59:581-590.

Schuckit, M., Smith, T., Daeppen, J.-B., Eng, M., Li, T.-K., Hesselbrock, V., Nurnberger, J., Jr., and Bucholz, K. (1998).
The clinical relevance of the distinction between alcohol dependence with and without a physiological component.
American Journal of Psychiatry 155(6):733-740. (pdf file)

Vedeniapin, A.B., Anokhin, A., Sirevaag, E., Rohrbaugh, J., and Cloninger, C. (1998).
Personality differences between smoking and non-smoking alcoholics.
Alcoholism: Clinical and Experimental Research 22:37A.

1997

Alexander, J.E. and Polich, J. (1997)
Handedness and P300 from Auditory Stimuli.
Brain and Cognition 1997; 35:259-270. PMID: 9356165 (pdf file)

Anokhin, A., Vedeniapin, A., and Sirevaag, E. (1997).
Frontal EEG asymmetry in depression and alcoholism: Effects of comorbidity and evidence for genetic influences.
Behavioral Genetics 27(6):583.

Blangero, J., Almasy, L., Williams, J., Porjesz, B., Reich, T., and Begleiter, H. (1997).
Incorporating quantitative traits in genomic scans of psychiatric diseases: Alcoholism and event-related potentials.
American Journal of Medical Genetics 74:602.

Crowe, R., Kramer, J., Hesselbrock, V., Manos, G., and Bucholz, K. (1997).
The utility of the "Brief MAST" and the "CAGE" in identifying alcohol problems: Results from a National high-risk and low-risk sample.
American Medical Association Archives of Family Medicine 6:477-483.

Dinwiddie, S. (1997).
Characteristics of injection drug users derived from a large family study of alcoholism.
Comprehensive Psychiatry 38(4):218-229.

Koziol, J.A., Alexander, J.E., Bauer, L.O., Kuperman, S., Morzorati, S., O’Connor, S.J., Rohrbaugh, J., Porjesz, B., Begleiter, H., and Polich, J. (1997).
A graphical technique for displaying correlation matrices.
The American Statistician 51:301-304. (pdf file)

Polich, J., Alexander, J., Kuperman, S., Morzorati, S., O'Connor, S.J., Porjesz, B., Rohrbaugh, J., and Begleiter, H. (1997).
P300 topography of amplitude/latency correlations.
Brain Topography 9:275-282. (pdf file)

Porjesz, B. and Begleiter, H. (1997).
Event-related potentials in COA's.
Alcohol Health and Research World 21:236-240. (pdf file)

Rohrbaugh, J.W., Dunham, D.N., Stewart, P.A., Bauer, L.O., Kuperman, S., O'Connor, S.J., Porjesz, B., and Begleiter, H. (1997).
Slow brain potentials in a visual-spatial memory task: Topographic distribution and inter-laboratory consistency.
International Journal of Psychophysiology 25:111-122. (pdf file)

Schuckit, M., Tipp, J., Bergman, M., Nurnberger, J., Jr., Reich, W., Hesselbrock, V., and Smith, T.A. (1997).
Comparison of induced and independent major depressive disorder in 2,945 alcoholics.
American Journal of Psychiatry 154(7):948-957.

Schuckit, M., Tipp, J., Bucholz, K., Nurnberger, J., Jr., Hesselbrock, V., Crowe, R., and Kramer, J. (1997).
The lifetime rates of three major mood disorders and four major anxiety disorders in alcoholics and controls.
Addiction 92(10):1289-1304. (pdf file)

Schuckit, M., Tipp, J., Smith, T., and Bucholz, K. (1997).
Periods of abstinence following the onset of alcohol dependence in 1,853 men and women.
Journal of Studies on Alcohol and Drugs 58:581-589.

Schuckit, M., Smith, T., and Tipp, J. (1997).
The self-rating of the effects of alcohol (SRE) form as a retrospective measure of the risk for alcoholism.
Addiction 92(8):979-988. (pdf file)

1996

Alexander, J.E., Bauer, L.O., Kuperman, S., Rohrbaugh, J., Morzorati, S., O'Connor, S.J., Porjesz, B., Begleiter, H., and Polich, J. (1996).
Hemispheric differences for P300 amplitude from an auditory oddball task.
International Journal of Psychophysiology 21:189-196. (pdf file)

Begleiter, H. (1996).
Genetics of alcoholics - an international perspective (symposium summary).
Alcoholism: Clinical and Experimental Research 20(8):78A-81A.

Bucholz, K., Heath, A., Reich, T., Hesselbrock, V., Kramer, J., Nurnberger, J., Jr., and Schuckit, M. (1996).
Can we subtype alcoholism? A latent class analysis of data from relatives of alcoholics in a multi-center family study of alcoholism.
Alcoholism: Clinical and Experimental Research 20(8):1462-1471.

Easton, C. and Bauer, L. (1996).
Neuropsychological correlates of urine toxicology results.
Progress in Neuropsychopharmacology & Biological Psychiatry 20:969-982. (pdf file)

Hesselbrock, V., Schuckit, M., Bierut, L., Nurnberger, J., Jr., and Bucholz, K. (1996).
Female alcoholism: New perspectives-findings from the COGA study (symposium summary).
Alcoholism: Clinical and Experimental Research Supplement 20(8):168A-171A. (pdf file)

Porjesz, B., Begleiter, H., Litke, A., Bauer, L.O., Kuperman, S., O’Connor, S.J., and Rohrbaugh, J. (1996).
Visual P3 as a potential phenotypic marker for alcoholism: Evidence from the COGA national project.
In: Ogura, C., Koga, Y., Shimokochi, M. (eds.), Recent Advances in Event-Related Brain Potential Research.
Elsevier Science, The Netherlands, 539-549.

Quaid, K., Dinwiddie, S., Conneally, P., and Nurnberger, J., Jr. (1996).
Issues in genetic testing for susceptibility to alcoholism: Lessons from Alzheimer's disease and Huntington's disease.
Alcoholism 20(8):1430-1437.

Reich, T.A., Begleiter, H., Edenberg, H.J., and Cloninger, C.R. (1996).
Genomic survey of alcohol dependence and related phenotypes: results from the Collaborative Study on the Genetics of Alcoholism (COGA).
Alcoholism: Clinical and Experimental Research Supplement 20(8):133A-137A. (pdf file)

Samar, V.J., Begleiter, H., Chapa, J.O., Raghuveer, M.R., Orlando, M., and Chorlian, D. (1996).
Matched Meyer neural wavelets for clinical and experimental analysis of auditory and visual evoked potentials.
In: Ramponi, G., Sicuranza, G.L., Carrato, S., and Marsi, S. (eds.), Signal Processing VIII, theories and applications; Proceedings of EUSIPCO-96, Vol. 1.
LINT Edition, Trieste, 387-390.

Schuckit, M., Tipp, J., Anthenelli, R., Bucholz, K., Hesselbrock, V., and Nurnberger, J., Jr. (1996).
Anorexia nervosa and Bulimia nervosa in alcohol-dependent men and women and their relatives.
American Journal of Psychiatry 153(1):74-82.

Schuckit, M., Tipp, J., Smith, T., Wiesbeck, G., and Kalmijn, J. (1996).
The relationship between self-rating of the effects (SRE) of alcohol and alcohol challenge results in 98 young men.
Journal of Studies on Alcohol and Drugs 58:397-404.

Schuckit, M., Tsuang, J., Anthenelli, R., Tipp, J., and Nurnberger, J., Jr. (1996).
Alcohol challenges in young men from alcoholic pedigrees and control families: A report from the COGA Project.
Journal of Studies on Alcohol and Drugs 57:368-377.

Wiesbeck, G., Schuckit, M., Kalmijn, J., Tipp, J., Bucholz, K., and Smith, T. (1996).
An evaluation of the history of marijuana withdrawal syndrome in a large population.
Addiction 91(10):1469-1478. (pdf file)

1995

Alexander, J.E. and Polich, J. (1995).
P300 differences between sinistrals and dextrals.
Cognitive Brain Research 2:277-280. PMID: 8580741 (pdf file)


Alexander, J.E., Porjesz, B., Bauer, L.O., Kuperman, S., Morzorati, S., O'Connor, S.J., Rohrbaugh, J., Begleiter, H., and Polich, J. (1995).
P300 hemispheric amplitude asymmetries from a visual oddball task.
Psychophysiology 32:467-475. (pdf file)

Begleiter, H. (1995).
The Collaborative Study on the Genetics of Alcoholism: Overview
Alcohol Health & Research World 19:228-236. (pdf file)

Begleiter, H., Reich, T., Hesselbrock, V.M., Porjesz, B., Li, T.K., Schuckit, M.A., Edenberg, H.J., and Rice, J.P. (1995).
The Collaborative Study on the Genetics of Alcoholism.
Alcohol Health & Research World 19:228-236. (pdf file)

Bucholz, K., Hesselbrock, V., Shayka, J., Nurnberger, J., Jr., Schuckit, M., Schmidt, I., Reich, T. (1995).
Reliability of individual diagnostic criterion items for psychoactive substance dependence and the impact on diagnosis.
Journal of Studies on Alcohol and Drugs 56:500-505.

Edenberg, H., Foroud, T., Goate, A., and Rice, J. (1995).
Microsatellite allele frequencies and heterozygosites in a large set of Caucasian, non-Hispanics in the United States.
The American Journal of Human Genetics Supplement 57:323A.

Koller, D.L., Foroud, T., Conneally, P.M., Reed, T., Edenberg, H.J., and Li, T.-K. (1995).
Linkage analysis of the MNS and esterase d chromosomal regions with alcohol dependence.
The American Journal of Human Genetics Supplement 57:324A.

Kuperman, S., Porjesz, B., Arndt, S., Bauer, L., Begleiter, H., Cizadlo, T., O'Connor, S., and Rohrbaugh, J. (1995).
Multi-center N400 ERP consistency using a primed and unprimed word paradigm.
Electroencephalography and Clinical Neurophysiology 94:462-470. (pdf file)

Porjesz, B. and Begleiter, H. (1995).
Overview: Neurophysiological component of the COGA National Project.
Alcohol Health & Research World 19(3):228-236.

Porjesz, B. and Begleiter, H. (1995).
The Collaborative Study on the Genetics of Alcoholism: Neurophysiological component
Alcohol Health & Research World 19:228-236. (pdf file)

Rice, J., Neuman, R., Hoshaw, S., Daw, E.W., and Gu, C. (1995).
TDT with covariates and genomic screens with MOD scores: Their behavior on simulated data.
Genetic Epidemiology 12:659-664. (pdf file)

Rice, J.P., Reich, T., Bucholz, K.K., Neuman, R.J., Fishman, R., Rochberg, N., Hesselbrock, V.M., Nurnberger, J.I., Jr., Schuckit, M.A., and Begleiter, H. (1995).
Comparison of direct interview and family history diagnoses of alcohol dependence.
Alcoholism: Clinical and Experimental Research 19:1018-1023. (pdf file)

Schuckit, M., Anthenelli, R., Bucholz, K., Hesselbrock, V., and Tipp, J. (1995).
The time course of development of alcohol-related problems in men and women.
Journal of Studies on Alcohol and Drugs 56:218-225.

Schuckit, M., Hesselbrock, V., Tipp, J., Nurnberger, J., Jr., Anthenelli, R., and Crowe, R. (1995).
Prevalence of major anxiety disorder in relatives of alcohol dependent men and women.
Journal of Studies on Alcohol and Drugs 56:309-317.

Schuckit, M., Tipp, J., Reich, T., Hesselbrock, V., and Bucholz, K. (1995).
The histories of withdrawal convulsions and delirium tremors in 1,648 alcohol dependent subjects.
Addiction 90:1335-1347. (pdf file)

Schuckit, M., Tipp, J., Smith, T., Shapiro, E., Hesselbrock, V., Bucholz, K., Reich, T., and Nurnberger, J., Jr. (1995).
An evaluation of type A and B alcoholics.
Addiction 90:1189-1203. (pdf file)

1994

Alexander, J.E., Polich, J., Bloom, F.E., Bauer, L.O., Kuperman, S., Rohrbaugh, J., Morzorati, S., O'Connor, S.J., Porjesz, B., and Begleiter, H. (1994).
P300 from an auditory oddball task: Inter-laboratory consistency.
International Journal of Psychophysiology 17:35-46. (pdf file)

Bucholz, K., Cadoret, R., Cloninger, C.R., Dinwiddie, S.H., Hesselbrock, V., Nurnberger, J., Jr., Reich, T., Schmidt, I., and Schuckit, M.A. (1994).
New semi-structured psychiatric interview for use in genetic linkage studies: A report on the reliability of the SSAGA.
Journal of Studies on Alcohol and Drugs 55:149-158.

Cohen, H.L., Wang, W., Porjesz, B., Bauer, L., Kuperman, S., O'Connor, S.J., Rohrbaugh, J., and Begleiter, H. (1994).
Visual P300: An interlaboratory consistency study.
Alcohol 11:583-587. (pdf file)

Schuckit, M. and Hesselbrock, V. (1994).
Alcohol dependence and anxiety disorders: What is the relationship.
The American Journal of Psychiatry 151:1723-1734. (pdf file)

Schuckit, M., Hesselbrock, V., Tipp, J., Anthenelli, R., Bucholz, K., and Radziminski, S. (1994).
A comparison of DSM-III-R, and ICD-10 substance use disorders diagnoses in 1922 men and women subjects in the COGA study.
Addiction 89:1629-1638. (pdf file)

Schuckit, M., Tipp, J., and Kelner, E. (1994).
Are daughters of alcoholics more likely to marry alcoholics?
The American Journal of Drug and Alcohol Abuse 20(2):237-245. (pdf file)

1992

Twitchell, G.R., Hertzog, C.A., Klein, J.L., and Schuckit, M.A. (1992).
Anatomy of a follow-up.
British Journal of Alcohol 87:1327-1333.

1990

Rice, J. (1990).
The use of computer simulation in genetic linkage studies.
Alcohol Health & Research World 14(3):253-257. (pdf file)