Find A PhysicianHome  |  Library  |  PRIME  |  Newsroom  |  A-Z Guide  |  E-mail  |  Contact Us  |  Directions

Collaborative Study on the Genetics of Alcoholism

 

Reviewed COGA articles (SAGE articles are marked with ****)

2012

**** Agrawal, A., Freedman, N.D., Cheng, Y.C., Lin, P., Shaffer, J.R., Sun, Q., Taylor, K., Yaspan, B., Cole, J.W., Cornelis, M.C., Desensi, R.S., Fitzpatrick, A., Heiss, G., Kang, J.H., O'Connell, J., Bennett, S., Bookman, E., Bucholz, K.K., Caporaso, N., Crout, R., Dick, D.M., Edenberg, H.J., Goate, A., Hesselbrock, V., Kittner, S., Kramer, J., Nurnberger, J.I. Jr, Qi, L., Rice, J.P., Schuckit, M., van Dam, R.M., Boerwinkle, E., Hu, F., Levy, S., Marazita, M., Mitchell, B.D., Pasquale, L.R., and Bierut, L.J.; for the GENEVA Consortium (2012)
Measuring alcohol consumption for genetic meta-analyses of alcohol intake: opportunities and challenges.
American Journal of Clinical Nutrition 95:539-547. PMID: 22301922 (pdf file)


**** Agrawal, A., Wetherill, L., Bucholz, K.K., Kramer, J., Kuperman, S., Lynskey, M.T., Nurnberger, J.I. Jr, Schuckit, M., Tischfield, J.A., Edenberg, H.J., Foroud, T., and Bierut, L.J. (2012)
Genetic influences on craving for alcohol.
Addictive Behaviors xx:xxx-xxx. PMID: 22481050
(pdf file)


Bierut, L.J., Goate, A.M., Breslau, N., Johnson, E.O., Bertelsen, S., Fox, L., Agrawal, A., Bucholz, K.K., Grucza, R., Hesselbrock, V., Kramer, J., Kuperman, S., Nurnberger, J., Porjesz, B., Saccone, N.L., Schuckit, M., Tischfield, J., Wang, J.C., Foroud, T., Rice, J.P., and Edenberg, H.J. (2012)
ADH1B is associated with alcohol dependence and alcohol consumption in populations of European and African ancestry.
Molecular Psychiatry 17:445-450. PMCID: PMC3252425 (pdf file)

Chen, A.C., Rangaswamy, M., and Porjesz, B. (2012).
Endophenotyes in Psychiatric Genetics.
In: Nurnberger, J. and Berretini, W. (eds.), Principles of Psychiatric Genetics. Cambridge University Press, xxx-xxx.

Edwards, A.C., Aliev, F., Bierut, L.J., Bucholz, K.K., Edenberg, H., Hesselbrock, V., Kramer ,J., Kuperman, S., Nurnberger, J.I. Jr, Schuckit, M.A., Porjesz, B., and Dick, D.M. (2012)
Genome-wide association study on comorbid depressive syndrome and alcohol dependence.
Psychiatric Genetics 22(1):31-41. PMCID: PMC3241912 (pdf file)

**** Hartz, S., Short, S., Saccone, N., Culverhouse, R., Chen, L., Schwantes-An, T., Coon, H., Han, Y., Stephens, S., Sun, J., Chen, X., Ducci, F., Dueker, N., Franceschini, N., Frank, J., Geller, F., Guðbjartsson, D., Hansel, N., Jiang, C., Keskitalo-Vuokko, K., Liu, J., Lyytikäinen, L., Michel, M., Rawal, R., Rosenberger, A., Scheet, P., Shaffer, J., Teumer, A., Thompson, J., Vink, J., Vogelzangs, N., Wenzlaff, A., Wheeler, W., Xiangjun, X., Yang, B., Aggen, S., Balmforth, A., Baumeister, S., Beaty, T., Bennett, S., Bergen, A., Boyd, H., Broms, U., Campbell, H., Chatterjee, N., Chen, J., Cheng, Y., Cichon, S., Couper, D., Cucca, F., Dick, D., Foroud, T., Furberg, H., Giegling, I., Gu, F., Hall, A., Hällfors, J., Han, S., Hartmann, A., Hayward, C., Heikkilä, K., Hewitt, J., Hottenga, J., Jensen, M., Jousilahti, P., Kaakinen, M., Kittner, S., Konte, B., Korhonen, T., Landi, M., Laatikainen, T., Leppert, M., Levy, S., Mathias, R., McNeil, D., Medland, S., Montgomery, G., Muley, T., Murray, T., Nauck, M., North, K., Pergadia, M., Polasek, O., Ramos, E., Ripatti, S., Risch, A., Ruczinski, I., Rudan, I., Salomaa, V., Schlessinger, D., Styrkársdóttir, U., Terracciano, A., Uda, M., Willemsen, G., Wu, X., Abecasis, G., Barnes, K., Bickeböller, H., Boerwinkle, E., Boomsma, D., Caporaso, N., Duan, J., Edenberg, H., Francks, C., Gejman, P., Gelernter, J., Grabe, H., Hops, H., Jarvelin, M., Jorma, V., Kähönen, M., Kendler, K., Lehtimäki, T., Levinson, D., Marazita, M., Marchini, J., Melbye, M., Mitchell, B., Murray, J., Nöthen, M., Penninx, B., Raitakari, O., Rietschel, M., Rujescu, D., Samani, N., Sanders, A., Schwartz, A., Shete, S., Shi, J., Spitz, M., Stefansson, K., Swan, G., Thorgeirsson, T., Völzke, H., Wei, Q., Wichmann, H., Amos, C., Breslau, N., Cannon, D., Ehringer, M., Grucza, R., Hatsukami, D., Heath, A., Johnson, E., Kaprio, J., Madden, P., Martin, N., Stevens, V., Stitzel, J., Weiss, R., Kraft, P., & Bierut, L. (2012).
Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers.
Archives of General Psychiatry
xx:xxx-xxx (in press) (supplement)

Kamarajan, C., Rangaswamy, M., Manz, N., Chorlian, D.B., Pandey, A.K., Roopesh, B.N., and Porjesz, B. (2012).
Topography, Power and Current Source Density of Theta Oscillations during Reward Processing as Markers for Alcohol Dependence.
Human Brain Mapping xx:xxx-xxx. (pdf file)


Kang, S.J., Rangaswamy, M., Manz, N., Wang, J.-C., Wetherill, L., Hinrichs, T., Almasy, L., Brooks, A., Chorlian, D.B., Dick, D., Hesselbrock, V., Kramer, J., Kuperman, S., Nurnberger Jr, J., Rice, J., Schuckit, M., Tischfield, J., Bierut, L.J., Edenberg, H.J., Goate, A., Foroud, T., and Porjesz, B. (2012).
Family-based Genome-wide Association Study of Frontal Theta Oscillations Identifies Potassium Channel Gene KCNJ6.
Genes, Brain and Behavior xx:xxx-xxx. (pdf file)

Kapoor, M., Wang, J.C., Bertelsen, S., Bucholz, K., Budde, J.P., Hinrichs, A., Agrawal, A., Brooks, A., Chorlian, D.B., Dick, D., Hesselbrock, V., Foroud, T., Kramer, J., Kuperman, J., Manz, N., Nurnberger Jr, J., Porjesz, B., Rice, J.P., Tischfield, J., Xuei, X., Schuckit, M., Edenberg, H.J., Bierut, L.J., and Goate, A. (2012).
Variants located upstream of CHRNB4 on chromosome 15q25.1 are associated with age at onset of daily smoking and habitual smoking.
PLoS ONE 7(3):e33513. (pdf file)


**** Lin, P., Hartz, S.M. Wang, J.-W. Agrawal, A., Zhang, T.-X. McKenna, N., Bucholz, K., Brooks, A.I., Tischfield, J.A., Edenberg, H.J., Hesselbrock, V.M., Kramer, J.R., Kuperman, S., Schuckit, M.A., Goate, A.M., Bierut, L.J., Rice, J.P., and COGA Collaborators, COGEND Collaborators, GENEVA (2012).
Copy Number Variations in 6q14.1 and 5q13.2 are Associated with Alcohol Dependence.
Alcoholism: Clinical and Experimental Research xx(x):xxx-xxx.


**** Luciano M, Lopez LM, de Moor MH, Harris SE, Davies G, Nutile T, Krueger RF, Esko T, Schlessinger D, Toshiko T, Derringer JL, Realo A, Hansell NK, Pergadia ML, Pesonen AK, Sanna S, Terracciano A, Madden PA, Penninx B, et al (2012).
Longevity candidate genes and their association with personality traits in the elderly.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
159B(2):192-200. PMID: 22213687. (pdf file)

**** Middeldorp, C.M., de Moor, M.H.M., McGrath, L.M., Gordon, S.D., Blackwood, D.H., Costa, P.T., Terracciano, A.., Krueger, R.F., de Geus, E.J.C., Nyholt, D.R., Tanaka, T., Esko, T., Madden, P.A.F., Derringer, J., Amin, N., Willemsen, G., Hottenga, J.-J., Distel, M.A., Uda, M., Sanna, S., Spinhoven, P., Hartman, C.A., Ripke, S., Sullivan, P.F., Realo, A., Allik, J., Heath, A.C., Pergadia, M.L., Agrawal, A., Lin, P., Grucza, R.A., Widen, E., Cousminer, D.L., Eriksson, J.G., Palotie, A., Barnett, J.H., Lee, P.H., Luciano, M., Tenesa, A., Davies, G., Lopez, L.M., Hansell, N.K., Medland, S.E., Ferrucci, L., Schlessinger, D., Montgomery, G.W., Wright, M.J., Aulchenko, Y.S., Janssens, A.C.J.W., Oostra, B.A., Metspalu, A., Abecasis, G.R., Deary, J., Räikkönen, K., Bierut, L.J., Martin, N.G., Wray, N.R., van Duijn, C.M., Smoller, J.W, Penninx, B.W.J.H, and Boomsma D.I. (2012).
The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data.
Translational Psychiatry
xx:xxx-xxx (pdf file and supplement figures 1A, 1B, 1C and Legend)

Pandey, A.K., Kamarajan, C., Rangaswamy, M., and Porjesz, B. (2012).
Event-Related Oscillations in Alcoholism Research: A Review.
Journal of Addiction Research & Therapy xx:xxx-xxx. (accepted for publication)

Pandey, A.K., Kamarajan, C., Tang, Y., Chorlian, D.B., Roopesh, B.N.,  Manz, N., Stimus, A., Rangaswamy, M.,  and Porjesz, B. (2012)

Neurocognitive Deficits in Male Alcoholics: An ERP/sLORETA Analysis of the N2 Component in an Equal Probability Go/NoGo Task .

Biological Psychiatry 89:170-182. PMCID: PMC3245806 (pdf file)

 

**** Rice, J.P., Hartz, S., Agrawal, A., Almasy, L., Bennett, S., Breslau, N., Bucholz, K.K., Doheny, K.F., Edenberg, H.J., Goate, A.M., Hesselbrock, V., Howells, W.B., Johnson, E.O., Kramer, J., Krueger, R.F., Kuperman, S., Laurie, C., Manolio, T.A., Neuman, R.J., Nurnberger Jr, J.I., Porjesz,B., Pugh, E., Ramos, E.M., Saccone, N., Saccone, S., Schuckit,M., and Bierut, L.J., as part of the GENEVA Consortium (2012)

CHRNB3 is more strongly associated with FTND-based nicotine dependence than cigarettes per day: phenotype definition changes GWAS results.

Addiction xx:xxx-xxx.


2011

Agrawal, A., Freedman, N.D., and Bierut, L.J. (2011)
Genome-wide association studies of alcohol intake--a promising cocktail?
American Journal of  Clinical Nutrition,
93(4):681-683. PMCID: PMC3057543. (pdf file)

**** Agrawal, A., Lynskey, M.T., Hinrichs, A., Grucza, R., Saccone, S.F., Krueger, R., Neuman, R., Howells, W., Fisher, S., Fox, L., Cloninger, R., Dick, D.M., Doheny, K.F., Edenberg, H.J., Goate, A.M., Hesselbrock, V., Johnson, E., Kramer, J., Kuperman, S., Nurnberger, J.I. Jr, Pugh, E., Schuckit, M., Tischfield, J., The GENEVA Consortium, Rice, J.P., Bucholz,, K.K., and Bierut, L.J. (2011)
A genome-wide association study of DSM-IV cannabis dependence.
Addiction Biology,
16(3):514-518. PMCID: PMC3117436.

**** Bennett SN, Caporaso N, Fitzpatrick AL, Agrawal A, Barnes K, Boyd HA, Cornelis MC, Hansel NN, Heiss G, Heit JA, Kang JH, Kittner SJ, Kraft P, Lowe W, Marazita ML, Monroe KR, Pasquale LR, Ramos EM, van Dam RM, et al (2011).
Phenotype harmonization and cross-study collaboration in GWAS consortia: the GENEVA experience.
Genet Epidemiol,
35(3):159-173. PMCID: PMC3055921.

Bierut, L.J. (2011).
Genetic Vulnerability and Susceptibility to Substance Dependence.
NEURON 69:618-627. PMCID: PMC3095110 (pdf file)

**** Derringer J, Krueger RF, Manz N, Porjesz B, Almasy L, Bookman E, Edenberg HJ, Kramer JR, Tischfield JA, Bierut LJ (2011).
Nonreplication of an association of SGIP1 SNPs with alcohol dependence and resting theta EEG power.
Psychiatric Genetics, 21(5):265-266. PMCID: PMC3139721. (pdf file and supplement)

Dick, D.M. (2011)
Gene-environment interaction in psychological traits and disorders.
Annual review of clinical psychology, 7:383-409. PMID: 21219196. (pdf file)

**** Dick, D.M., Aliev, F., Krueger, R.F., Edwards, A., Agrawal, A., Lynskey, M., Lin, P., Schuckit, M., Hesselbrock, V., Nurnberger, J. Jr, Almasy, L., Porjesz, B., Edenberg, H.J., Bucholz, K., Kramer, J., Kuperman, S., and Bierut, L. as part of the SAGE and GENEVA Consortia (2011).
Genome-wide association study of conduct disorder symptomatology.
Molecular Psychiatry 16:800-808. PMID: 20585324, NIHMSID: 264833 (pdf file)

Dick, D.M., Meyers, J.L., Latendresse, S.J., Creemers, H.E., Lansford, J.E., Pettit, G.S., Bates, J.E., Dodge, K.A., Budde, J., Goate, A., Buitelaar, J.K., Ormel, J., Verhulst, F.C., and Huizink, A.C. (2011)
CHRM2, parental monitoring, and adolescent externalizing behavior: evidence for gene-environment interaction.
Psychol Sciences
22(4):481-489. PMID: 21441226.

Edenberg, H. (2011)
Common and Rare Variants in Alcohol Dependence.
Biological Psychiatry 70(6):498-499. PMID: 21864733 (pdf file)

**** Hartz SM, Johnson EO, Saccone NL, Hatsukami D, Breslau N, Bierut LJ (2011).
Inclusion of African Americans in genetic studies: what is the barrier?
American Journal of Epidemiology
174(3):336-344. PMCID: PMC3202157.

Hinrichs, A., Culverhouse, R., and Suarez, B. (2011)
Linkage analysis merging replicate phenotypes: an application to three quantitative phenotypes in two African samples.
BMC Proceedings
5(Suppl 9):S81. (pdf file)

Johnson, C., Drgon, T., Walther, D., and Uhl, G.R. (2011)
Genomic regions identified by overlapping clusters of nominally-positive SNPs from genome-wide studies of alcohol and illegal substance dependence.
PLoS One 6(7):e19210. PMCID: PMC3144872. (pdf file)

Latendresse, S.J., Bates, J.E., Goodnight, J.A., Lansford, J.E., Budde, J.P., Goate, A., Dodge, K.A., Pettit, G.S., and Dick, D.M. (2011)
Differential susceptibility to adolescent externalizing trajectories: examining the interplay between CHRM2 and peer group antisocial behavior.
Child development 82(6):1797-814. PMCID: PMC3218245.

**** Lin, P., Hartz, S.M., Wang, J.C., Krueger, R.F., Foroud, T.M., Edenberg, H.J., Nurnberger, J.I. Jr, Brooks, A.I., Tischfield, J.A., Almasy, L., Webb, B.T., Hesselbrock, V.M., Porjesz, B., Goate, A.M., Bierut, L.J., Rice, J.P.,COGA Collaborators, COGEND Collaborators, and GENEVA (2011).
Copy number variation accuracy in genome-wide association studies.
Human Heredity 71(3):141-147. PMID: 21778733 (pdf file)

Maher, B.S., Vladimirov, V.I., Latendresse, S.J., Thiselton, D.L., McNamee, R., Kang, M., Bigdeli, T.B., Chen, X., Riley, B.P., Hettema, J.M., Chilcoat, H., Heidbreder, C., Muglia, P., Murrelle, E.L., Dick, D.M., Aliev, F., Agrawal, A., Edenberg, H.J., Kramer, J., Nurnberger, J., Tischfield, J.A,. Devlin, B., Ferrell, R.E., Kirillova, G.P., Tarter, R.E., Kendler, K.S., and Vanyukov, M.M. (2011).
The AVPR1A gene and substance use disorders: association, replication, and functional evidence.
Biological Psychiatry 70(6):519-527. PMID: 21514459 (pdf file)

McCutcheon, V.V., Agrawal, A., Heath, A.C., Edenberg, H.J., Hesselbrock, V.M., Schuckit, M.A., Kramer, J.R., and Bucholz, K.K. (2011).
Functioning of alcohol use disorder criteria among men and women with arrests for driving under the influence of alcohol.
Alcoholism: Clinical and Experimental Research,
35(11):1985-1993. PMCID: PMC3166544. (pdf file)

Schuckit, M.A., Smith, T.L., Trim, R.S., Allen, R.C., Fukukura, T., Knight, E.E., Cesario, E.M., and Kreikebaum, S.A. (2011).
A prospective evaluation of how a low level of response to alcohol predicts later heavy drinking and alcohol problems.
American Journal of Drug Alcohol Abuse,
37(6):479-86. PMID: 21797810.

Schumann, G., Coin, L.J., Lourdusamy, A., Charoen, P., Berger, K.H., Stacey, D., Desrivières, S., Aliev, F.A., Khan, A.A., Amin, N., Aulchenko, Y.S., Bakalkin, G., Bakker, S.J., Balkau, B., Beulens, J.W., Bilbao, A., de Boer, R.A., Beury, D., Bots, M.L., Breetvelt, E.J., Cauchi, S., Cavalcanti-Proença, C., Chambers, J.C., Clarke, T.K., Dahmen, N., de Geus, E.J., Dick, D., Ducci, F., Easton, A., Edenberg, H.J., Esk, T., Fernández-Medarde, A., Foroud, T., Freimer, N.B., Girault, J.A., Grobbee, D.E., Guarrera, S., Gudbjartsson, D.F., Hartikainen, A.L., Heath, A.C., Hesselbrock, V., Hofman, A., Hottenga, J.J., Isohanni, M.K., Kaprio, J., Khaw, K.T., Kuehnel, B., Laitinen, J., Lobbens, S., Luan, J., Mangino, M., Maroteaux, M., Matullo, G., McCarthy, M.I., Mueller, C., Navis, G., Numans, M.E., Núñez, A., Nyholt, D.R., Onland-Moret, C.N., Oostra, B.A., O'Reilly, P.F., Palkovits, M., Penninx, B.W., Polidoro, S., Pouta, A., Prokopenko, I., Ricceri, F., Santos, E., Smit, J.H., Soranzo, N., Song, K., Sovio, U., Stumvoll, M., Surakk, I., Thorgeirsson, T.E., Thorsteinsdottir, U., Troakes, C., Tyrfingsson, T., Tönjes, A., Uiterwaal, C.S., Uitterlinden, A.G., van der Harst, P., van der Schouw, Y.T., Staehlin, O., Vogelzangs, N., Vollenweider, P., Waeber, G., Wareham, N.J., Waterworth, D.M., Whitfield, J.B., Wichmann, E.H., Willemsen, G., Witteman, J.C., Yuan, X., Zhai, G., Zhao, J.H., Zhang, W., Martin, N.G., Metspalu, A., Doering, A., Scott, J., Spector, T.D., Loos, R.J., Boomsma, D.I., Mooser, V., Peltonen, L., Stefansson, K., van Duijn, C.M., Vineis, P., Sommer, W.H., Kooner, J.S., Spanagel, R., Heberlein, U.A., Jarvelin, M.R., and Elliott, P. (2011)
Genome-wide associations and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption.
Proceeding of the National Academy of Sciences USA 108(17):7119-7124. PMID: 3084048 (pdf file and supplement)

Zlojutro, M., Manz, N., Rangaswamy, M., Xuei, X.,  Flury-Wetherill, L., Koller, D., Bierut, L.J.,  Goate, A., Hesselbrock, V., Kuperman, S., Nurnberger Jr., J., Rice, J.P., Schuckit, M.A., Foroud, T., Edenberg, H.J., Porjesz, B., and Almasy, L. (2011).
Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 156B(1):44-58. PMCID: PMC3139811, PMID: 21184583 (pdf file)

2010

**** Anney R, Klei L, Pinto D, Regan R, Conroy J, Magalhaes TR, Correia C, Abrahams BS, Sykes N, Pagnamenta AT, Almeida J, Bacchelli E, Bailey AJ, Baird G, Battaglia A, Berney T, Bolshakova N, Bolte S, Bolton PF, Bourgeron T, Brennan S, Brian J, Carson AR, Casallo G, Casey J, Chu SH, Cochrane L, Corsello C, Crawford EL, Crossett A, Dawson G, de Jonge M, Delorme R, Drmic I, Duketis E, Duque F, Estes A, Farrar P, Fernandez BA, Folstein SE, Fombonne E, Freitag CM, Gilbert J, Gillberg C, Glessner JT, Goldberg J, Green J, Guter SJ, Hakonarson H, Heron EA, Hill M, Holt R, Howe JL, Hughes G, Hus V, Igliozzi R, Kim C, Klauck SM, Kolevzon A, Korvatska O, Kustanovich V, Lajonchere CM, Lamb JA, Laskawiec M, Leboyer M, Le Couteur A, Leventhal BL, Lionel AC, Liu XQ, Lord C, Lotspeich L, Lund SC, Maestrini E, Mahoney W, Mantoulan C, Marshall CR, McConachie H, McDougle CJ, McGrath J, McMahon WM, Melhem NM, Merikangas A, Migita O, Minshew NJ, Mirza GK, Munson J, Nelson SF, Noakes C, Noor A, Nygren G, Oliveira G, Papanikolaou K, Parr JR, Parrini B, Paton T, Pickles A, Piven J, Osey DJ, Poustka A, Poustka F, Prasad A, Ragoussis J, Renshaw K, Rickaby J, Roberts W, Roeder K, Roge B, Rutter ML, Bierut LJ, Rice JP, Salt J, Sansom K, Sato D, Segurado R, Senman L, Shah N, Sheffield VC, Soorya L, Sousa I, Stoppioni V, Strawbridge C, Tancredi R, Tansey K, Thiruvahindrapduram B, Thompson AP, Thomson S, Tryfon A, Tsiantis J, Van Engeland H, Vincent JB, Volkmar F, Wallace S, Wang K, Wang ZZ, Wassink TH, Wing K, Wittemeyer K, Wood S, Yaspan BL, Zurawiecki D, Zwaigenbaum L, Betancur C, Buxbaum JD, Cantor RM, Cook EH, Coon H, Cuccaro ML, Gallagher L, Geschwind DH, Gill M, Haines JL, Miller J, Monaco AP, Nurnberger JI, Paterson AD, Pericak-Vance MA, Schellenberg GD, Scherer SW, Sutcliffe JS, Szatmari P, Vicente AM, Vieland VJ, Wijsman EM, Devlin B, Ennis S, Hallmayer J (2010).
A genome-wide scan for common alleles affecting risk for autism.
Human Molecular Genetics, 19(20):4072-4082. PMCID: PMC2947401. (pdf file)

Bauer, L., Dick, D., Bierut, L., Bucholz, K., Edenberg, H., Kuperman, S., Kramer, J., Nurnberger, J., O'Connor, S., Rice, J., Rohrbaugh, J., Schuckit, M., Tischfield, J., Porjesz, B. and Hesselbrock, V. (2010).
Obesity, smoking, and frontal brain dysfunction.
The American Journal on Addictions 19:391-400. PMCID: PMC2924769 (pdf file)

**** Bierut, L.J., Agrawal, A., Bucholz, K.K., Doheny, K.F., Laurie, C., Pugh, E., Fisher, S., Fox, L., Howells, W., Bertelsen, S., Hinrichs, A.L., Almasy, L., Breslau, N., Culverhouse, R.C., Dick, D.M., Edenberg, H.J., Foroud, T., Grucza, R.A., Hatsukami, D., Hesselbrock, V., Johnson, E.O., Kramer, J., Krueger, R.F., Kuperman, S., Lynskey, M., Mann, K., Neuman, R.J., Nöthen, M.M., Nurnberger, J.I. Jr, Porjesz, B., Ridinger, M., Saccone, N.L., Saccone, S.F., Schuckit, M.A., Tischfield, J.A., Wang, .J.C, Rietschel, M., Goate, A.M., and Rice, J.P., as part of the Gene, Environment Association Studies (GENEVA) Consortium (2010).
A genome-wide association study of alcohol dependence.
Proceedings of the National Academy of Sciences of the United States of America 107:5082-5087. PMCID: PMC2841942 (pdf file and supplement)

Cavazos-Rehg, P.A. Spitznagel, E.L., Bucholz, K.K., Nurnberger Jr., J., Edenberg, H.J., Kramer, J.R., Kuperman, S., Hesselbrock, V., and Bierut, L.J. (2010).

Predictors of Sexual Debut at Age 16 or Younger.

Archives of Sexual Behavior 39:664-673. PMCID: PMC2855761, PMID: 18846417 (pdf file)

Chen, A.C., Manz, N., Tang, Y., Rangaswamy, M., Almasy, L., Kuperman, S., Nurnberger Jr., J. , O'Connor, S.J., Edenberg, H.J., Schuckit, M.A., Tischfield, J., Foroud, T., Bierut, L.J., Rohrbaugh, J., Rice, J.P., Goate, A., Hesselbrock, V., and Porjesz, B. (2010).

Single Nucleotide Polymorphisms in Corticotropin Releasing Hormone Receptor 1 Gene (CRHR1) Are Associated with Quantitative Traits of Event-Related Potential and Alcohol Dependence.

Alcoholism: Clinical and Experimental Research 34:988-996. PMCID: PMC 2878886, PMID: 20374216 (pdf file)

**** Cornelis, M.C., Agrawal, A., Cole, J.W., Hansel, N.N., Barnes, K.C., Beaty, T.H., Bennett, S.N., Bierut, L.J., Boerwinkle, E., Doheny, K.F., Feenstra, B., Feingold, E., Fornage, M., Haiman, C.A., Harris, E.L., Hayes, M.G., Heit, J.A., Hu, F.B., Kang, J.H., et al (2010). The Gene, Environment Association Studies consortium (GENEVA): maximizing the knowledge obtained from GWAS by collaboration across studies of multiple conditions.
Genetic Epidemiology,
34(4):364-372. PMCID: PMC2860056 (pdf file)

**** de Moor MH, Costa PT, Terracciano A, Krueger RF, de Geus EJ, Toshiko T, Penninx BW, Esko T, Madden PA, Derringer J, Amin N, Willemsen G, Hottenga JJ, Distel MA, Uda M, Sanna S, Spinhoven P, Hartman CA, Sullivan P, et al (2010). Meta-analysis of genome-wide association studies for personality.
Mol Psychiatry. PMID: 21173776.

**** Derringer, J., Krueger, R.F., Dick, D.M., Saccone, S., Grucza, R.A., Agrawal, A., Lin, P., Almasy, L., Edenberg, H.J., Foroud, T., Nurnberger, J.I. Jr, Hesselbrock, V.M., Kramer, J.R., Kuperman, S., Porjesz, B., Schuckit, M.A., and Bierut, L.J.; Gene Environment Association Studies (GENEVA) Consortium (2010).
Predicting Sensation Seeking From Dopamine Genes: A Candidate-System Approach.
Psychological Science 21:1282-1290. PMCID: PMC3139721 (pdf file)

Dick, D.M., Meyers, J., Aliev, F., Nurnberger, J. Jr, Kramer, J., Kuperman, S., Porjesz, B., Tischfield, J., Edenberg, H.J., Foroud, T., Schuckit, M., Goate, A., Hesselbrock, V., and Bierut, L. (2010).
Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts.
Neuropsychiatric Genetics Part B: American Journal of Medical Genetics 153B(6):1179-1188. PMID: 20468071 (pdf file)

Dick, D.M., Smith, G., Olausson, P., Mitchell, S.H., Leeman, R.F., O'Malley, S.S., and Sher, K. (2010).
Understanding the construct of impulsivity and its relationship to alcohol use disorders.
Addiction Biology 15(2):217-226. PMCID: PMC2895996 (pdf file)

Edenberg, H.J., Koller, D.L., Xuei, X., Wetherill, L., McClintick, J.N., Almasy, L., Bierut, L.J., Bucholz, K.K., Goate, A., Aliev, F., Dick, D., Hesselbrock, V., Hinrichs, A., Kramer, J., Kuperman, S., Nurnberger, J.I. Jr, Rice, J.P., Schuckit, M.A., Taylor, R., Todd Webb, B., Tischfield, J.A., Porjesz, B., and Foroud, T. (2010).
Genome-Wide Association Study of Alcohol Dependence Implicates a Region on Chromosome 11.
Alcoholism: Clinical and Experimental Research 34:840-852. PMCID: PMC2884073 (pdf file)

**** Elks CE, Perry JR, Sulem P, Chasman DI, Franceschini N, He C, Lunetta KL, Visser JA, Byrne EM, Cousminer DL, Gudbjartsson DF, Esko T, Feenstra B, Hottenga JJ, Koller DL, Kutalik Z, Lin P, Mangino M, Marongiu M, McArdle PF, Smith AV, Stolk L, van Wingerden SH, Zhao JH, Albrecht E, Corre T, Ingelsson E, Hayward C, Magnusson PK, Smith EN, Ulivi S, Warrington NM, Zgaga L, Alavere H, Amin N, Aspelund T, Bandinelli S, Barroso I, Berenson GS, Bergmann S, Blackburn H, Boerwinkle E, Buring JE, Busonero F, Campbell H, Chanock SJ, Chen W, Cornelis MC, Couper D, Coviello AD, d'Adamo P, de Faire U, de Geus EJ, Deloukas P, Döring A, Smith GD, Easton DF, Eiriksdottir G, Emilsson V, Eriksson J, Ferrucci L, Folsom AR, Foroud T, Garcia M, Gasparini P, Geller F, Gieger C; GIANT Consortium, Gudnason V, Hall P, Hankinson SE, Ferreli L, Heath AC, Hernandez DG, Hofman A, Hu FB, Illig T, Järvelin MR, Johnson AD, Karasik D, Khaw KT, Kiel DP, Kilpeläinen TO, Kolcic I, Kraft P, Launer LJ, Laven JS, Li S, Liu J, Levy D, Martin NG, McArdle WL, Melbye M, Mooser V, Murray JC, Murray SS, Nalls MA, Navarro P, Nelis M, Ness AR, Northstone K, Oostra BA, Peacock M, Palmer LJ, Palotie A, Paré G, Parker AN, Pedersen NL, Peltonen L, Pennell CE, Pharoah P, Polasek O, Plump AS, Pouta A, Porcu E, Rafnar T, Rice JP, Ring SM, Rivadeneira F, Rudan I, Sala C, Salomaa V, Sanna S, Schlessinger D, Schork NJ, Scuteri A, Segrè AV, Shuldiner AR, Soranzo N, Sovio U, Srinivasan SR, Strachan DP, Tammesoo ML, Tikkanen E, Toniolo D, Tsui K, Tryggvadottir L, Tyrer J, Uda M, van Dam RM, van Meurs JB, Vollenweider P, Waeber G, Wareham NJ, Waterworth DM, Weedon MN, Wichmann HE, Willemsen G, Wilson JF, Wright AF, Young L, Zhai G, Zhuang WV, Bierut LJ, Boomsma DI, Boyd HA, Crisponi L, Demerath EW, van Duijn CM, Econs MJ, Harris TB, Hunter DJ, Loos RJ, Metspalu A, Montgomery GW, Ridker PM, Spector TD, Streeten EA, Stefansson K, Thorsteinsdottir U, Uitterlinden AG, Widen E, Murabito JM, Ong KK, Murray A. (2010).
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.
Nature Genetics,
42(12):1077-1085. PMCID: PMC3140055. (pdf file and supplemantary pdf files and excel file)

Grucza, R.A., Krueger, R.F., Racette, S.B., Norberg, K.E., Hipp, P.R., and Bierut, L.J. (2010)
The emerging link between alcoholism risk and obesity in the United States.
Archives of Genetic Psychiatry,
67(12):1301-1308. PMCID: PMC3110764. (pdf file)

Hartz, S.M. and Bierut, L.J. (2010)
Genetics of addictions.
Clin Lab Med, 30(4):847-864. PMCID: PMC3047506 (pdf file)

Kalsi, G., Kuo, P.H., Aliev, F., Alexander, J., McMichael, O., Patterson, D.G., Walsh, D., Zhao, Z., Schuckit, M., Nurnberger, J., Jr., Edenberg, H., Kramer, J., Hesselbrock, V., Tischfield, J.A., Vladimirov, V., Prescott, C.A., Dick, D.M., Kendler, K.S., Riley, B.P. (2010)
A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.
Human Molecular Genetics,
19(12):2497-506. PMCID: PMC2876884. (pdf file)

Kamarajan, C., Rangaswamy, M., Tang, Y., Chorlian, D.B., Pandey, A.K., Roopesh, B.N., Manz, N., Saunders, R., Stimus, A.T., and Porjesz, B. (2010).
Dysfunctional reward processing in male alcoholics: An ERP study during a gambling task.
Journal of Psychiatric Research 44:576-590. (pdf file)

Kramer, J., Chan, G., Hesselbrock, V.M., Kuperman, S., Bucholz, K.K., Edenberg, H.J., Schuckit, M., Nurnberger Jr., J., Foroud, T., Dick, D.M., Bierut, L., and Porjesz, B. (2010).
A Principle Components Analysis of the abbreviated Desires for Alcohol Questionaire (DAQ).
Journal of Studies on Alcohol and Drugs 71:150-155. PMCID: PMC2815057 (pdf file)

**** Laurie CC, Doheny KF, Mirel DB, Pugh EW, Bierut LJ, Bhangale T, Boehm F, Caporaso NE, Cornelis MC, Edenberg HJ, Gabriel SB, Harris EL, Hu FB, Jacobs KB, Kraft P, Landi MT, Lumley T, Manolio TA, McHugh C, Painter I, Paschall J, Rice JP, Rice KM, Zheng X, Weir BS; GENEVA Investigators. (2010).
Quality control and quality assurance in genotypic data for genome-wide association studies.
Genetic Epidemiology,
34(6):591-602. PMCID: PMC3061487 (pdf file)

**** Lin P, Hartz SM, Zhang Z, Saccone SF, Wang J, Tischfield JA, Edenberg HJ, Kramer JR, A MG, Bierut LJ, Rice JP, COGA Collaborators, COGEND Collaborators, GENEVA (2010).
A new statistic to evaluate imputation reliability.
PLoS ONE, 5(3):e9697. PMCID: PMC2837741 (pdf file)

Meyers, J.L. and Dick, D.M. (2010).

Genetic and family risk factors for youth adolescent onset substance use disorders.

Child and Adolescent Psychiatric Clinics of North America 19(3):465-477. PMCID: PMC20682215

**** Noor A, Whibley A, Marshall CR, Gianakopoulos PJ, Piton A, Carson AR, Orlic-Milacic M, Lionel AC, Sato D, Pinto D, Drmic I, Noakes C, Senman L, Zhang X, Mo R, Gauthier J, Crosbie J, Pagnamenta AT, Munson J, Estes AM, Fiebig A, Franke A, Schreiber S, Stewart AF, Roberts R, McPherson R, Guter SJ, Cook EH Jr, Dawson G, Schellenberg GD, Battaglia A, Maestrini E; Autism Genome Project Consortium, Jeng L, Hutchison T, Rajcan-Separovic E, Chudley AE, Lewis SM, Liu X, Holden JJ, Fernandez B, Zwaigenbaum L, Bryson SE, Roberts W, Szatmari P, Gallagher L, Stratton MR, Gecz J, Brady AF, Schwartz CE, Schachar RJ, Monaco AP, Rouleau GA, Hui CC, Lucy Raymond F, Scherer SW, Vincent JB. (2010).
Disruption at the PTCHD1 Locus on Xp22.11 in Autism spectrum disorder and intellectual disability.
Sci Transl Med,
2(49):49ra68. PMCID: PMC2987731. (pdf file)

**** Pinto D, Pagnamenta AT, Klei L, Anney R, Merico D, Regan R, Conroy J, Magalhaes TR, Correia C, Abrahams BS, Almeida J, Bacchelli E, Bader GD, Bailey AJ, Baird G, Battaglia A, Berney T, Bolshakova N, Bölte S, Bolton PF, Bourgeron T, Brennan S, Brian J, Bryson SE, Carson AR, Casallo G, Casey J, Chung BH, Cochrane L, Corsello C, Crawford EL, Crossett A, Cytrynbaum C, Dawson G, de Jonge M, Delorme R, Drmic I, Duketis E, Duque F, Estes A, Farrar P, Fernandez BA, Folstein SE, Fombonne E, Freitag CM, Gilbert J, Gillberg C, Glessner JT, Goldberg J, Green A, Green J, Guter SJ, Hakonarson H, Heron EA, Hill M, Holt R, Howe JL, Hughes G, Hus V, Igliozzi R, Kim C, Klauck SM, Kolevzon A, Korvatska O, Kustanovich V, Lajonchere CM, Lamb JA, Laskawiec M, Leboyer M, Le Couteur A, Leventhal BL, Lionel AC, Liu XQ, Lord C, Lotspeich L, Lund SC, Maestrini E, Mahoney W, Mantoulan C, Marshall CR, McConachie H, McDougle CJ, McGrath J, McMahon WM, Merikangas A, Migita O, Minshew NJ, Mirza GK, Munson J, Nelson SF, Noakes C, Noor A, Nygren G, Oliveira G, Papanikolaou K, Parr JR, Parrini B, Paton T, Pickles A, Pilorge M, Piven J, Ponting CP, Posey DJ, Poustka A, Poustka F, Prasad A, Ragoussis J, Renshaw K, Rickaby J, Roberts W, Roeder K, Roge B, Rutter ML, Bierut LJ, Rice JP, Salt J, Sansom K, Sato D, Segurado R, Sequeira AF, Senman L, Shah N, Sheffield VC, Soorya L, Sousa I, Stein O, Sykes N, Stoppioni V, Strawbridge C, Tancredi R, Tansey K, Thiruvahindrapduram B, Thompson AP, Thomson S, Tryfon A, Tsiantis J, Van Engeland H, Vincent JB, Volkmar F, Wallace S, Wang K, Wang Z, Wassink TH, Webber C, Weksberg R, Wing K, Wittemeyer K, Wood S, Wu J, Yaspan BL, Zurawiecki D, Zwaigenbaum L, Buxbaum JD, Cantor RM, Cook EH, Coon H, Cuccaro ML, Devlin B, Ennis S, Gallagher L, Geschwind DH, Gill M, Haines JL, Hallmayer J, Miller J, Monaco AP, Nurnberger JI Jr, Paterson AD, Pericak-Vance MA, Schellenberg GD, Szatmari P, Vicente AM, Vieland VJ, Wijsman EM, Scherer SW, Sutcliffe JS, Betancur C. (2010).
Functional impact of global rare copy number variation in autism spectrum disorders.
Nature,
466(7304):368-372. PMCID: PMC3021798.

Saccone, S.F., Bolze, R., Thomas, P., Quan, J., Mehta, G., Deelman, E., Tischfield, J.A., and Rice, J.P. (2010)
SPOT: a web-based tool for using biological databases to prioritize SNPs after a genome-wide association study.
Nucleic acids research, 38(Web Server issue):W201-9. PMCID: PMC2896195. (pdf file)

**** Saccone NL, Culverhouse RC, Schwantes-An TH, Cannon DS, Chen X, Cichon S, Giegling I, Han S, Han Y, Keskitalo-Vuokko K, Kong X, Landi MT, Ma JZ, Short SE, Stephens SH, Stevens VL, Sun L, Wang Y, Wenzlaff AS, Aggen SH, Breslau N, Broderick P, Chatterjee N, Chen J, Heath AC, Heliövaara M, Hoft NR, Hunter DJ, Jensen MK, Martin NG, Montgomery GW, Niu T, Payne TJ, Peltonen L, Pergadia ML, Rice JP, Sherva R, Spitz MR, Sun J, Wang JC, Weiss RB, Wheeler W, Witt SH, Yang BZ, Caporaso NE, Ehringer MA, Eisen T, Gapstur SM, Gelernter J, Houlston R, Kaprio J, Kendler KS, Kraft P, Leppert MF, Li MD, Madden PA, Nöthen MM, Pillai S, Rietschel M, Rujescu D, Schwartz A, Amos CI, Bierut LJ. (2010).
Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.
PLoS Genet,
6(8). PMCID: PMC2916847 (pdf file)

Xuei X., Flury-Wetherill L., Dick D., Goate A., Tischfield J., Nurnberger J. Jr, Schuckit M., Kramer J., Kuperman S., Hesselbrock V., Porjesz B., Foroud T., and Edenberg H.J. (2009)
GABRR1 and GABRR2, encoding the GABA-A receptor subunits r1 and r2, are associated with alcohol dependence.
American Journal of Medical Genetics B: Neuropsychiatric Genetics 153B(2):418-427. PMCID: PMC2829340 (pdf file)

2009

Agrawal, A., Wetherill, L., Dick, D.M., Xuei, X., Hinrichs, A.L., Hesselbrock, V., Kramer, J.,Nurnberger, J.I. Jr, Schuckit, M.A., Bierut., L.J., Edenberg, H.J., and Foroud, T. (2009).
Evidence for association between polymorphisms in the cannabinoid receptor 1 (CNR1) gene and cannabis dependence.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 150B:736-740. PMID: 19536785, PMCID: PMC2703788 (pdf file)

Cavazos-Rehg, P.A. Spitznagel, E.L., Schootman, M., Strickland, J.R., Afful, S.E., Cottler, L.B., and Bierut, L.J. (2010).

Risky Sexual Behaviours and Sexually Transmitted Diseases: A Comparison Study of Cocaine-Dependent Individuals in Treatment versus a Community-Matched Sample.

AIDS Patient Care and STDs 23:727-734. PMCID: PMC2804246 (pdf file)

Chen, A., Tang, Y., Rangaswamy, M., Almasy, L., Kuperman, S., Nurnberger Jr. J., O'Connor, S., Edenberg, H., Schuckit, M., Tischfield, J., Foroud, T., Bierut, L., Rohrbaugh, J., Bauer, L., Rice, J., Hesselbrock, V., Goate, A., and Porjesz, B. (2009).
Association of Single Nucleotide Polymorphisms in a Glutamate Receptor Gene (GRM8) with Theta Power of Event-Related Oscillations and Alcohol Dependence.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 150B:359-368. PMCID:PMC2660384 (pdf file)

Chorlian, D.B., Rangaswamy, M., and Porjesz, B. (2009).
EEG Coherence: Topography and Frequency Structure.
Experimental Brain Research 198:59-83. PMID: 1962316, PMCID: PMC2645043 (pdf file)

Grucza, R., Norberg, K., and Bierut, L. (2009).

Binge Drinking Among Youth and Young Adults in the United States.

J Am Acad Child Adolesc Psychiatry 48(7):692-702. PMID: 19465879, PMCID: PMC2862553 (pdf file)

Hurley, J., Ballard, C., and Edenberg, H. (2009).

Altering the Relative Abundance of GABAA Receptor Subunits Changes GABA- and Ethanol-Responses in Xenopus Oocytes.

Alcoholism: Clinical and Experimental Research 33(6):1089-1096. PMID: 19382902 (pdf file)

Kamarajan, C., Porjesz, B., Rangaswamy, M., Tang, Y., Chorlian, D.B., Padmanabhapillai, A., Saunders, R., Pandey, A.K., Roopesh, B.N., Manz, N., Stimus, A.T., and Begleiter, H. (2009).
Brain signatures of monetary loss and gain: Outcome-related potentials in a single outcome gambling task.
Behavioural Brain Research 197:62-76. PMCID: PMC2645043 (pdf file)

Kramer J, Chan G, Kuperman S, Bucholz K, Edenberg H, Schuckit M, Polgreen L, Kapp E, Hesselbrock V, Nurnberger Jr. J,and Bierut L. (2009) .

A Comparison of Diagnoses Obtained from In-Person and Telephone Interviews, Using the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA).

J Stud Alcohol Drugs 70(4):623-627. PMCID: PMC2696302 (pdf file)

McCutcheon V, Heath A, Edenberg H, Grucza R, Hesselbrock V, Kramer J, Bierut L,and Bucholz K. (2009).

Alcohol Criteria Endorsement and Psychiatric and Drug Use Disorders Among DUI Offenders: Greater Severity Among Women and Multiple Offenders.

Addict Behav 34(5):432-439. PMID: 19167170 (pdf file)

Norberg, K.E., Bierut, L.J., and Grucza, R.A. (2009).
Long-term effects of minimum drinking age laws on past-year alcohol and drug use disorders.
Alcohol Clin Exp Res,
33(12):2180-2190. PMCID: PMC3018854. (pdf file)

Roopesh, B.N., Rangaswamy, M., Kamarajan, C., Chorlian, D.B., Stimus, A.T., Bauer, L.O., Rohrbaugh, J. O'Connor, S.J., Kuperman, S., Schuckit, M., and Porjesz, B. (2009).
Priming Deficiency in Male Subjects at Risk for Alcoholism: The N4 During a Lexical Decision Task.
Alcoholism: Clinical and Experimental Research 33:2027-2036. PMID: 19764939, PMCID: PMC2924769 (pdf file)

Schuckit, M.A. (2009)

Alcohol-use disorders.

Lancet 373(9662):492-501. PMID: 19168210 (pdf file)

Schuckit, M.A., Smith, T.L., Danko, G.P., Trim, R., Bucholz, K.K., Edenberg, H.J., Hesselbrock, V., Kramer, J.J., and Dick, D.M. (2009)

An evaluation of the full level of response to alcohol model of heavy drinking and problems in COGA offspring.

J Stud Alcohol Drugs 70(3):436-445. PMCID: PMC2670749 (pdf file)

Schuckit, M.A., Smith, T.L., Trim, R., Fukukura, T., and Allen, R. (2009)

The Overlap in Predicting Alcohol Outcome for Two Measures of the Level of Response to Alcohol.

Alcoholism: Clinical and Experimental Research 33(3):563-569. PMCID: PMC2670749, NIHMSID: 84626 (pdf file)

Wang, J.C., Cruchaga, C., Saccone, N.L., Bertelsen, S., Liu, P., Budde, J.P., Duan, W., Fox, L., Grucza, R.A., Kern, J., Mayo, K., Reyes, O., Rice, J., Saccone, S.F., Spiegel, N., Steinbach, J.H., Stitzel, J.A., Anderson, M.W., You, M., Stevens, V.L., Bierut, L.J., and Goate, A.M.; COGEND collaborators and GELCC collaborators (2009)
Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.
Human Molecular Genetics, 18(16):3125-3135. PMCID: PMC2714722 (pdf file)

Wang, J.C., Grucza, R., Cruchaga, C., Hinrichs, A.L., Bertelsen, S., Budde, J.P., Fox, L., Goldstein, E., Reyes, O., Saccone, N., Saccone, S., Xuei, X., Bucholz, K., Kuperman, S., Nurnberger, J. Jr, Rice, J.P., Schuckit, M., Tischfield, J., Hesselbrock, V., Porjesz, B., Edenberg, H.J., Bierut, L.J., and Goate, A.M. (2009).
Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence.
Molecular Psychiatry 14(5):501-510. PMID: 18414406 (pdf file)

2008

Agrawal, A., Hinrichs, A.L., Dunn, G., Bertelsen, S., Dick, D.M., Saccone, S.F., Saccone, N.L., Grucza, R.A., Wang, J.C., Cloninger, C.R., Edenberg, H.J., Foroud, T., Hesselbrock, V., Kramer, J., Bucholz, K.K., Kuperman, S., Nurnberger, J.I. Jr, Porjesz, B., Schuckit, M.A., Goate, A.M., and Bierut., L.J. (2008).
Linkage scan for quantitative traits identifies new regions of interest for substance dependence in the Collaborative Study on the Genetics of Alcoholism (COGA) sample.
Drug and Alcohol Dependence 93(1-2):12-20. PMCID: PMC2266629. (pdf file)

Bierut, L.J., Stitzel, J.A., Wang, J.C., Hinrichs, A.L., Grucza, R.A., Xuei, X., Saccone, N.L., Saccone, S.F., Bertelsen, S., Fox, L., Horton, W.J., Breslau, N., Budde, J., Cloninger, C.R., Dick, D.M., Foroud, T., Hatsukami, D., Hesselbrock, V., Johnson, E.O., Kramer, J., Kuperman, S., Madden, P.A.F., Mayo, K., Nurnberger, J., Jr, Pomerleau, O., Porjesz, B., Reyes, O., Schuckit, M., Swan, G., Tischfield, J.A., Edenberg, H.J., Rice, J.P., and Goate, A.M. (2008).
Variants in Nicotinic Receptors and Risk for Nicotine Dependence.
American Journal of Psychiatry 165(9):1163-1171. PMCID: PMC2574742  (pdf file)

Dick, D. and Agrawal, A. (2008)

The Genetics of Alcohol and Other Drug Dependence.

Alcohol Res Health 31(2):111-118.

Dick, D.M., Aliev, F., Wang, J.C., Grucza, R.A., Schuckit, M., Kuperman, S., Kramer, J., Hinrichs, A., Bertelsen, S., Budde, J.P., Hesselbrock, V., Porjesz, B., Edenberg, H.J., Bierut, L.J., and Goate, A. (2008)
Using dimensional models of externalizing psychopathology to aid in gene identification.
Archives of General Psychiatry 65(3):310-318. PMID: 18316677  (pdf file)

Dick, D.M., Aliev, F., Wang, J.C., Saccone, S., Hinrichs, A., Bertelsen, S., Budde, J., Saccone, N., Foroud, T., Nurnberger, J. Jr, Xuei, X., Conneally, P.M., Schuckit, M., Almasy, L., Crowe, R., Kuperman, S., Kramer, J., Tischfield, J.A., Hesselbrock, V., Edenberg, H.J., Porjesz, B., Rice, J.P., Bierut, L., and Goate, A. (2008).
A Systematic Single Nucleotide Polymorphism Screen to Fine-Map Alcohol Dependence Genes on Chromosome 7 Identifies Association With a Novel Susceptibility Gene ACN9.
Biological Psychiatry 63(11):1047-1053. PMID: 18163977 (pdf file)

Edenberg, H.J., Xuei, X.L., Wetherill, L.F., Bierut, L., Bucholz, K., Dick, D.M., Hesselbrock, V., Kuperman, S., Porjesz, B., Schuckit, M.A., Tischfield, J.A., Almasy, L.A., Nurnberger, J.I., and Foroud, T. (2008).
Association of NFKB1, which encodes a subunit of the transcription factor NF-κB, with alcohol dependence.
Human Molecular Genetics 17(7):963-970. PMID: 18079108  (pdf file)

Edenberg H, Wang, Tian H, Pochareddy S, Xuei X, Wetherill L, Goate A, Hinrichs T, Kuperman S, Nurnberger Jr. J, Schuckit M, Tischfield J, and Foroud T. A (2008)

Regulatory Variation in OPRK1, the Gene Encoding the K-Opioid Receptor, is Associated with Alcohol Dependence.

Human Molecular Genetics 17(12):1783-1789. PMCID: PMC2405904 ,PMID: 18319328 (pdf file)

Foroud T, Flury-Wetherill L, Kramer J, Tischfield J, Nurnberger Jr. J, Schuckit M, Xuei X,and Edenberg H. (2008)

The Tachykinin Receptor 3 (Tacr3) is Associated with Alcohol and Cocaine Dependence.

Alcoholism: Clinical and Experimental Research32(6): 1023-1030. PMCID: PMC2430628 , PMID: 18422838 (pdf file)

Ghosh, S., Bierut, L.J., Porjesz, B., Edenberg, H.J., Dick, D., Goate, A., Hesselbrock, V., Nurnberger, J. Jr, Foroud, T., Kramer, J., Rice, J., and Begleiter, H.(2008).
A novel non-parametric regression reveals linkage on chromosome 4 for the number of externalizing symptoms in sib-pairs.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 147B:1301-1305. PMCID: PMC2879266  (pdf file)

Grucza R, Bucholz K, Rice J, and Bierut L. (2008)

Secular Trends in the Lifetime Prevalence of Alcohol Dependence in the United States: A Re-Evaluation.

Alcohol Res Health 32(5):763-770. PMCID: PMC2443101 , PMID: 18336633 (pdf file)

Grucza R, Norberg K, Bucholz K, and Bierut L. (2008)

Correspondence Between Secular Changes in Alcohol Dependence and Age of Drinking Onset Among Women in the United States.

Alcoholism: Clinical and Experimental Research 32(8):1493-1501. PMCID: PMC2661151 , PMID: 18564104 (pdf file)

Grucza, R.A., Wang, J.C., Stitzel, J.A., Hinrichs, A.L., Saccone, S.F., Saccone, N.L., Bucholz, K.K., Cloninger, C.R., Neuman, R.J., Budde, J.P., Fox, L., Bertelsen, S., Kramer, J., Hesselbrock, V., Tischfield, J., Nurnberger, J.I. Jr, Almasy, L., Porjesz, B., Kuperman, S., Schuckit, M.A., Edenberg, H.J., Rice, J.P., Goate, A.M., and Bierut, L.J. (2008).
A Risk Allele for Nicotine Dependence in CHRNA5 Is a Protective Allele for Cocaine Dependence.
Biological Psychiatry 64(11):922-929. PMCID: PMC2582594 (pdf file)

Kramer, J., Chan, G., Dick, D., Kuperman, S., Bucholz, K., Hesselbrock, V., Edenberg, H., Polgreen, L., Hesselbrock, V., Schuckit, M., Nurnberger Jr., J., Kapp, E., Porjesz, B., and Bierut, L. (2008)
Multiple-Domain Predictors of Problematic Alcohol Use in Young Adulthood.
Journal of Studies on Alcohol and Drugs 69(5):649-459. PMCID: PMC2575389 (pdf file)

Rangaswamy, M. and Porjesz, B. (2008).
Uncovering genes for cognitive (dys)function and predisposition for alcoholism spectrum disorders: A review of human brain oscillations as effective endophenotypes.
Brain Research 1235:153-171. PMCID: PMC2814598  (pdf file)

Rangaswamy, M. and Porjesz, B. (2008).
From Event-related Potential to Oscillations: Genetic Diathesis in Brain (Dys)Function and Alcohol Dependence.
Alcohol Research & Health 31:238-242. (pdf file)

Schuckit M, Danko G, Smith T, Bierut L, Bucholz K, Edenberg H, Hesselbrock V, Kramer J, Nurnberger Jr. J, Allen R, Kreikebaum S, and Hinga B.

The Prognostic Implications of DSM-IV Abuse Criteria in Drinking Adolescents.

Drug Alcohol Depend 2008; 97(1-2):94-104. PMCID: PMC2581466 , PMID: 18479842

Schuckit M, Smith T, Hesselbrock V, Bucholz K, Bierut L, Edenberg H, Kramer J, Longacre E, Fukukura T, Kalmijn J, Danko G, and Trim R.

Clinical Implications of Tolerance to Alcohol in Nondependent Young Drinkers.

Am J Drug Alcohol Abuse 2008; 34(2):133-149. PMID: 18293230

Wetherill, L., Schuckit, M.A., Hesselbrock, V., Xuei, X., Liang, T., Dick, D.M., Kramer, J., Nurnberger Jr, J.I., Tischfield, J.A., Porjesz, B., Edenberg, H.J., and Foroud, T. (2008).
Neuropeptide Y Receptor Genes Are Associated With Alcohol Dependence, Alcohol Withdrawal Phenotypes, and Cocaine Dependence.
Alcoholism: Clinical and Experimental Research 32(12):2031-2040. PMCID: PMC2650441 (pdf file)

Xuei, X., Flury-Wetherill, L., Almasy, L., Bierut, L., Tischfield, J., Schuckit, M., Nurnberger Jr., J., Foroud, T., and Edenberg, H. (2008)

Association Analysis of Genes Encoding the Nociceptin Receptor (OPRL1) and its Endogeneous Ligand (PNOC) with Alcohol or Illicit Drug Dependence.

Addiction Biology 13(1):80-87. PMID: 17910740

2007

Chorlian, D.B., Tang, Y., Rangaswamy, M., O'Connor, S.J., Rohrbaugh, J., Taylor, R., and Porjesz, B. (2007).
Heritability of EEG coherence in a large sib-pair population.
Biological Psychology 75:260-266. (pdf file)

Connor K, Hesselbrock V, Meldrum S, Schuckit M, Bucholz K, Gamble S, Wines J, and Kramer J. (2007)

Transitions to, and Predictors of, Suicidal Ideation, Plans and Unplanned- and Planned Suicide Attempts Among 3729 Men and Women with Alcohol Dependence.

J Stud Alcohol Drugs 68(5):654-662. (pdf file)

Dick, D. (2007).

Indentification of Genes Influencing a Spectrum of Externalizing Psychopathology.

Current Directions in Psychological Science 16(6):331-335.

Dick D, Agrawal A, Wang J, Hinrichs A, Bertelsen S, Bucholz K, Schuckit M, Kramer J, Edenberg H, Nurnberger Jr. J, Tischfield J, Goate A, and Bierut L. (2007)

Alcohol Dependence with Comorbid Drug Dependence: Genetic and Phenotypic Associations Suggest a More Severe Form of the Disorder with Stronger Genetic Contribution to Risk.

Addiction 102:1131-1139. (pdf file)

Dick, D.M., Aliev, F., Kramer, J., Wang, J.C., Hinrichs, A., Bertelsen, S., Kuperman, S., Schuckit, M., Nurnberger, J., Edenberg, H.J., Porjesz, B., Begleiter, H., Hesselbrock, V., Goate, A., and Bierut, L. (2007).
Association of CHRM2 with IQ: Converging Evidence for a Gene Influencing Intelligence.
Behavior Genetics 37:265-272. (pdf file)

Dick D, Aliev F, Wang J, Saccone S, Hinrichs A, Bertelsen S, Budde J, Saccone N, Foroud T, Nurnberger Jr. J, Xuei X, Conneally P, Schuckit M, Almasy L, Crowe R, Kuperman S, Kramer J, Tischfield J, Hesselbrock V, Edenberg H, Porjesz B, Rice J, Bierut L, and Goate A. (2007)

A Systematic SNP Screen to Fine-Map Alcohol Dependence Genes on Chromosome 7 Identifies Association with a Novel Susceptibility Gene ACN9.

Biological Psychiatry 63(11):1047-1053. PMID: 18163977 (pdf file)

Dick D, Plunkett J, Hamlin D, Nurnberger Jr. J, Kuperman S, Schuckit M, Hesselbrock V, Edenberg H, and Bierut L. (2007)

Association Analyses of the Serotonin Transporter Gene with Lifetime Depression and Alcohol Dependence in the Collaborative Study on the Genetics of Alcoholism (COGA) Sample.

Psychiatric Genetics 17(1):35-38.

Dick, D.M., Wang, J.C., Plunkett, J., Aliev, F., Hinrichs, A., Bertelsen, S., Budde, J.P., Goldstein, E.L., Kaplan, D., Edenberg, H.J., Nurnberger, J. Jr, Hesselbrock, V., Schuckit, M., Kuperman, S., Tischfield, J., Porjesz, B., Begleiter, H., Bierut, L., and Goate, A. (2007).
Family-based association analyses of alcohol dependence phenotypes across DRD2 and neighboring gene ANKK1.
Alcoholism: Clinical and Experimental Research 31:1645-1653. (pdf file)

Foroud T, Flury-Wetherill L, Dick D, Hesselbrock V, Nurnberger Jr. J, Kramer J, Tischfield J, Schuckit M, Bierut L, Xuei X,and Edenberg H. (2007).

Lack of Association of Alcohol Dependence and Habitual Smoking with catechol-O-methyltransferase (COMT).

Alcoholism: Clinical and Experimental Research 31(11):1773-1779. (pdf file)

Foroud, T., Flury-Wetherill, L., Liang, T., Dick, D.M., Hesselbrock, V., Kramer, J., Nurnberger, Jr J.I., Schuckit, M., Carr, L., Porjesz, B., Xuei, X., and Edenberg, H.J. (2007).
Association of Alcohol Craving With α-Synuclein (SNCA).
Alcoholism: Clinical and Experimental Research 31:537-545. (pdf file)

Hesselbrock V and Hesselbrock M. (2007)

Are There Empirically Supported and Clinically Useful Subtypes [of Alcohol Dependence]?. Book chapter in Diagnostic Issues in Substance Use Disorders. Schuckit MA, Sirovatka P & Regier DA. (Eds.)

American Psychiatric Assoc. pp. 171-171.

Nurnberger Jr. J and Bierut L. (2007)

Seeking the Connections: Alcoholism and Our Genes.

Sci Am 46-53.

Nurnberger Jr. J, Kuperman S, Flury-Wetherill L, and Meyer E.

Genetics of Comorbid Mood Disorder and Alcohol Dependence.

Journal of Dual Diagnosis: Research and Practice in Substance Abuse Comorbidity 2007; 3(2):31-46.

Porjesz, B. and Li, T.K. (2007).
Impulsivity and addiction: a tribute to Henri Begleiter.
TheScientificWorldJOURNAL 7:131-141. (pdf file)

Porjesz, B. and Rangaswamy, M. (2007).
Neurophysiological endophenotypes, CNS disinhibition, and risk for alcohol dependence and related disorders.
TheScientificWorldJOURNAL 7:121-123. (pdf file)

Rangaswamy, M., Jones, K.A., Porjesz, B., Chorlian, D.B., Padmanabhapillai, A., Kamarajan, C. Kuperman, S., Rohrbaugh, J., O'Connor S., Bauer L.O., Schuckit, M., and Begleiter, H. (2007).
Delta and theta oscillations as risk markers in adolescent offspring of alcoholics.
International Journal of Psychophysiology 63:3-15. (pdf file).

Schuckit M, Smith T, Danko G, Pierson J, Trim R, Nurnberger Jr. J, Kramer J, Kuperman S, Bierut L, and Hesselbrock V. (2007)

A Comparison of Factors Associated with Substance-Induced Versus Independent Depressions.

J Stud Alcohol Drugs 68:805-812. (pdf file)

Tang, Y., Chorlian, D.B., Rangaswamy, M., O'Connor S., Taylor, R., Rohrbaugh, J., Porjesz, B., and Begleiter, H. (2007).
Heritability of Bipolar EEG Spectra in a Large Sib-pair Population.
Behavior Genetics 37:302-313. (pdf file)

Tang, Y., Chorlian, D.B., Rangaswamy, M., Porjesz, B., Bauer, L., Kuperman, S., O'Connor, S., Schuckit, M., Stimus, A., and Begleiter, H. (2007).
Genetic influences on bipolar EEG power spectra.
International Journal of Psychophysiology 657:2-9. (pdf file)

Wang J, Hinrichs A, Bertelsen S, Stock H, Budde J, Dick D, Bucholz K, Rice J, Saccone N, Edenberg H, Hesselbrock V, Kuperman S, Schuckit M, Bierut L, and Goate A. (2007)

Functional Variants in TAS2R38 and TAS2R16 Influence Alcohol Consumption in High-Risk Families of African American Origin.

Alcohol Clin Exp Res 31:209-215. (pdf file)

Xuei X, Flury-Wetherill L, Bierut L, Dick D, Nurnberger Jr. J, Foroud T, and Edenberg H. (2007)

The Opioid System and Alcohol and Drug Dependence: Family-Based Association Study.

Am J Med Genet B Neuropsychiatr Genet 144B:877-884. (pdf file)

2006

Agrawal, A., Edenberg, H.J., Foroud, T., Bierut, L.J., Dunne, G., Hinrichs, A.L., Nurnberger, J.I., Crowe, R., Kuperman, S., Schuckit, M.A., Begleiter, H., Porjesz, B., and Dick, D.M. (2006).
Association of GABRA2 with Drug Dependence in the Collaborative Study of the Genetics of Alcoholism Sample.
Behavior Genetics 36:640-50. (pdf file)

Begleiter, H. and Porjesz, B. (2006).
Genetics of human brain oscillations.
International Journal of Psychophysiology 60:162-171. (pdf file)

Bucholz K, Nurnberger Jr., J, Kramer J, Hesselbrock V, Schuckit M, and Bierut L. (2006).

Comparison of Psychiatric Diagnoses From Interview with Those From Best-estimate Procedures.

J Stud Alcohol 67(1):157-168. (pdf file)

Connor K, Hesselbrock V, Schuckit M, Hirsch J, Knox K, Meldrum S, Bucholz K, Kramer J, Kuperman S, Preuss U, and Soyka M. (2006).

Precontemplated and Impulsive Suicide Attempts Among Individuals with Alcohol Dependence.

J Stud Alcohol 67(1):95-101. (pdf file)

 

Dick, D.M., Agrawal, A., Schuckit, M.A., Bierut, L., Hinrichs, A., Fox, L., Mullaney, J., Cloninger, C.R., Hesselbrock, V., Nurnberger, J.I., Jr., Almasy, L., Foroud, T., Porjesz, B., Edenberg, H., and Begleiter, H. (2006).
Marital status, alcohol dependence, and GABRA2: evidence for gene-environment correlation and interaction.
Journal of Studies on Alcohol 67:185-194. (pdf file)

Dick, D.M., Aliev, F., Bierut, L., Goate, A., Rice, J., Hinrichs, A., Bertelsen, S., Wang, J.C., Dunn, G., Kuperman, S., Schuckit, M., Nurnberger, J., Jr., Porjesz, B., Begleiter, H., Kramer, J., and Hesselbrock, V. (2006).
Linkage analyses of IQ in the collaborative study on the genetics of alcoholism (COGA) sample.
Behavior Genetics 36:77-86. (pdf file)

Dick, D. and Bierut, L. (2006).

The Genetics of Alcohol Dependence.

Curr Psychiatry Rep 2006; 8:151-157.

Dick, D.M., Bierut, L., Hinrichs, A., Fox, L., Bucholz, K.K., Kramer, J., Kuperman, S., Hesselbrock, V., Schuckit, M., Almasy, L., Tischfield, J., Porjesz, B., Begleiter, H., Nurnberger, J., Jr., Xuei, X., Edenberg, H.J., and Foroud, T. (2006).
The Role of GABRA2 in Risk for Conduct Disorder and Alcohol and Drug Dependence across Developmental Stages.
Behavior Genetics 36:577-590. (pdf file)

Dick, D.M., Jones, K., Saccone, N., Hinrichs, A., Wang, J.C., Goate, A., Bierut, L., Almasy, L., Schuckit, M., Hesselbrock, V., Tischfield, J., Foroud, T., Edenberg, H., Porjesz, B., and Begleiter, H. (2006).
Endophenotypes successfully lead to gene identification: results from the collaborative study on the genetics of alcoholism.
Behavior Genetics 36:112-126. (pdf file)

Dick D, Plunkett J, Flury L, Xuei X, Goate A, Hesselbrock V, Schuckit M, Crowe R, Edenberg H, and Foroud T. (2006).

Association Between GABRA1 and Drinking Behaviors in the Collaborative Study on the Genetics of Alcoholism Sample.

Alcohol Clin Exp Res 2006; 30(7):1101-1110. (pdf file)

Duncan A, Neuman R, Kramer J, Kuperman S, Hesselbrock V, and Bucholz K. (2006).

Lifetime Psychiatric Comorbidity of Alcohol Dependence and Bulimia Nervosa in Women.

Drug Alcohol Depend 2006; 84:122-132. (pdf file)

Edenberg, H. and Foroud, T. (2006)

The Genetics of Alcoholism: Identifying Specific Genes Through Family Studies.

Addiction Biol 2006; 11(3-4):386-396.

Edenberg, H.J., Xuei, X., Chen, H.J., Tian, H., Wetherill, L.F., Dick, D.M., Almasy, L., Bierut, L., Bucholz, K.K., Goate, A., Hesselbrock, V., Kuperman, S., Nurnberger, J., Porjesz, B., Rice, J., Schuckit, M., Tischfield, J., Begleiter, H., and Foroud, T. (2006).
Association of alcohol dehydrogenase genes with alcohol dependence: a comprehensive analysis.
Human Molecular Genetics 15:1539-1549. (pdf file)

Fisher S, Bucholz K, Reich W, Fox L, Kuperman S, Kramer J, Hesselbrock V, Dick D, Nurnberger JI, Jr., Edenberg H, and Bierut L. (2006).

Teenagers Are Right-Parents Don't Know Much: An Analysis of Adolescent-Parent Agreement on Reports of Adolescent Substance Use, Abuse and Dependence.

Alcohol Clin Exp Res 2006; 30(19):1699-1710. (pdf file)

Gogineni A, King S, Jackson K, Kramer J, Bucholz K, Chan G, Iacono W, Kuperman S, Larkins J, Longabaugh R, McGue M, Polgreen L, Sher K, Stout R, Strong D, and Woolard R.

Female Offspring of Alcoholic Individuals: Recent Findings on Alcoholism and Psychopathology Risks: Symposium Presented at the Research Society on Alcoholism, 2004, Vancouver Aruna Gogineni, Chair.

Alcohol Clin Res Exp 2006; 30(2):377-387. (pdf file)

Grucza, R. and Bierut, L. (2006)

Cigarette Smoking and the Risk for Alcohol Use Disorders Among Adolescent Drinkers.

Alcohol Clin Res Exp 2006; 30(12):2046-2054. PMID: 17117970

Grucza, R. and Bierut, L. (2006)

Co-Occurring Risk Factors for Alcohol Dependence and Habitual Smoking: Update on Findings from the Collaborative Study on the Genetics of Alcoholism.

Alcohol Res Health 2006; 29(3):172-178. PMID: 17373405 (pdf file)

Grucza R, Cloninger CR, Bucholz K, Constantino J, Schuckit M, Dick D, and Bierut L. (2006).

Novelty Seeking as a Moderator of Familial Risk for Alcohol Dependence.

Alcohol Clin Exp Res 2006; 30(7):1176-1183. (pdf file)

Hayden, E.P., Wiegand, R.E., Meyer, E.T., Bauer, L.O., O'Connor, S.J., Nurnberger Jr., J.I., Chorlian, D.B., Porjesz, B., and Begleiter, H. (2006).
Patterns of Regional Brain Activity in Alcohol-Dependent Subjects.
Alcoholism: Clinical and Experimental Research 30:1986-1991. (pdf file)

Hesselbrock, V. and Hesselbrock, M. (2006).

Are There Empirically Supported and Clinically Useful Subtypes of Alcohol Dependence?.

Addiction 101 Suppl 1:97-103. (pdf file)

Hesselbrock, V. and Hesselbrock, M. (2006)

Developmental Perspectives on the Risk for Developing Substance Abuse Problems. Book chapter in Rethinking Substance Abuse: What the Science Shows and What We Should Do about it.

Miller WR & Carroll KM (Eds.) New York: Guilford Press 2006; pp. 97-114.

Hinrichs, A.L., Wang, J.C., Bufe, B., Kwon, J.M., Budde, J., Allen, R., Bertelsen, S., Evans, W., Dick, D., Rice, J., Foroud, T., Nurnberger, J., Tischfield, J.A., Kuperman, S., Crowe, R., Hesselbrock, V., Schuckit, M., Almasy, L., Porjesz, B., Edenberg, H.J., Begleiter, H., Meyerhof, W., Bierut, L.J., and Goate, A.M. (2006).
Functional variant in a bitter-taste receptor (hTAS2R16) influences risk of alcohol dependence.
American Journal of Human Genetics 78:103-111. (pdf file)

Johnson C, Drgon T, Liu Q, Walther D, Edenberg H, Rice J, Foroud T, and Uhl G. (2006).

Pooled Association Genome Scanning for Alcohol Dependence Using 104,268 SNPs: Validation and Use to Identify Alcoholism Vulnerability Loci in Unrelated Individuals from the Collaborative Study on the Genetics of Alcoholism.

Am J Med Genet B Neuropsychiatr Genet 141(8):844-853. (pdf file)

Jones, K.A., Porjesz, B., Chorlian, D., Rangaswamy, M., Kamarajan, C., Padmanabhapillai, A., Stimus, A., and Begleiter, H. (2006)
S-transform time-frequency analysis of P300 reveals deficits in individuals diagnosed with alcoholism.
Clinical Neurophysiology 117:2128-2143. (pdf file)

Jones, K.A., Porjesz, B., Almasy, L., Bierut, L., Goate, A., Hinrichs, A., Rice, J.P., Rohrbaugh, J., Bauer, L.O., Crowe, R.R., Edenberg, H.J., Foroud, T., Hesselbrock, V., Kuperman, S., Nurnberger Jr, J., O'Connor, S.J., Schuckit, M.A., Tischfield, J.A., and Begleiter, H. (2006).
A Cholinergic Receptor Gene (CHRM2) Affects Event-related Oscillations.
Behavior Genetics 36:627-39. (pdf file)

Kamarajan, C., Porjesz, B., Jones, K., Chorlian, D., Padmanabhapillai, A., Rangaswamy, M., Stimus, A., and Begleiter, H. (2006).
Event-related oscillations in offspring of alcoholics: neurocognitive disinhibition as a risk for alcoholism.
Biological Psychiatry 59:625-634. (pdf file)

Ohannessian C, Hesselbeck V, Ruddy K, Kramer J, Kuperman S, Bucholz K, and Schuckit M. (2006).

The Effects of Parental Substance Use on Adolescent Psychological Adjustment: A Micro-level Approach.

The Prevention Researcher 2006; 13(4):7-9.

Padmanabhapillai, A., Porjesz, B., Ranganathan, M., Jones, K.A., Chorlian, D.B., Tang, Y., Kamarajan, C., Rangaswamy, M., Stimus, A., and Begleiter, H. (2006).
Suppression of early evoked gamma band response in male alcoholics during a visual oddball task.
International Journal of Psychophysiology 60:15-26. (pdf file)

Padmanabhapillai, A., Tang, Y., Ranganathan, M., Rangaswamy, M., Jones, K.A., Chorlian, D.B., Kamarajan, C., Stimus, A.T., Kuperman, S., Rohrbaugh, J., O'Connor, S.J., Bauer, L.O., Schuckit, M.A., Begleiter, H., and Porjesz, B. (2006).
Evoked gamma band response in male adolescent subjects at high risk for alcoholism during a visual oddball task .
International Journal of Psychophysiology 62:262-271. (pdf file)

Schuckit M, Smith T, Danko G, Pierson J, Hesselbrock V, Bucholz K, Kramer J, Kuperman S, Dietiker C, Brandon R, and Chan G. (2006).

The Ability of the Self-Rating of the Effects of Alcohol (SRE) Scale to Predict Alcohol-Related Outcomes Five Years Later.

J Stud Alcohol 68(3):371-378. (pdf file)

Schuckit M, Windle M, Smith T, Hesselbrock V, Ohannessian C, Averna S, Bauer L, Kramer J, Bucholz K, and Sher K. (2006).

Searching for the Full Picture: Structural Equation Modeling in Alcohol Research.

Alcohol Clin Exp Res 2006; 30(2):194-202. (pdf file)

Volkow, N.D., Wang, G.-J., Begleiter, H., Porjesz, B., Fowler, J.S., Telang, F., Wong, C., Ma, Y., Logan, J.,Goldstein, R., Alexoff, B., and Thanos, P.K. (2006).
High Levels of Dopamine D2 Receptors.
Archives of General Psychiatry 63:999-1006. (pdf file)

Wang, K., Porjesz, B., Jones, K., and Begleiter, H. (2006)

Genetic Linkage and Linkage Disequilibrium Analysis.

In: Encyclopedia of Biopharmaceutical Statistics, New York: Taylor and Francis. pp. 1-12.

Xuei, X., Dick, D., Flury-Wetherill, L., Tian, H.-J., Agrawal, A., Bierut, L., Goate, A., Bucholz, K., Schuckit, M., Nurnberger, Jr J.I., Tischfield, J., Kuperman, S., Porjesz, B., Begleiter, H., Foroud, T., and Edenberg, H.J. (2006).
Association of the κ-opioid system with alcohol dependence.
Molecular Psychiatry 11:1016-1024. (pdf file)

2005

Bailey-Wilson, J.E., Almasy, L., de Andrade, M., Bailey, J., Bickeböller, H., Cordell, H.J., Daw, E.W., Goldin, L., Goode, E.L., Gray-McGuire, C., Hening, W., Jarvik, G., Maher, B.S., Mendell, N., Paterson, A.D., Rice, J., Satten, G., Suarez, B., Vieland, V., Wilcox, M., Zhang. H., Ziegler, A., MacCluer, J.W. (2005).
Genetic Analysis Workshop 14: mirosatellite and single-nucleotide polymorphism marker loci for genome-wide scans.
BMC Genetics 6: Supplement 1. (pdf file)

Ceballos N, Houston R, Smith N, Bauer L, Taylor R. (2005)

N400 as an Index of Semantic Expectancies: Differential Effects of Alcohol and Cocaine Dependence.

Prog Neuropsychopharmacol Biol Psychiatry 29:936-432. (pdf file)

Corbett, J., Saccone, N.L., Foroud, T., Goate, A., Edenberg, H., Nurnberger, J., Porjesz, B., Begleiter, H., Reich, T., and Rice, J.P. (2005).
A sex-adjusted and age-adjusted genome screen for nested alcohol dependence diagnoses.
Psychiatric Genetics 15:25-30. (pdf file)

Culverhouse, R., Bucholz, K.K., Crowe, R.R., Hesselbrock, V., Nurnberger, J., Jr., Porjesz, B., Schuckit, M.A., Reich, T., Bierut, L.J. (2005).
Long-term Stability of Alcohol and Other Substance Dependence Diagnoses and Habitual Smoking: an evaluation after 5 years.
Archives of General Psychiatry 62:753-760. (pdf file)

Dick D, Edenberg H, Xuei X, Goate A, Hesselbrock V, Schuckit M, Crowe R, Foroud T. No Association GABAA Receptor Genes on Chromosome 5 with Alcoholism in the Collaborative Study on the Genetics of Alcoholism Sample. Am J Med Genet Neuropsychiatr Genet 2005; 132(1):24-28. (pdf file)

Duncan AE, Neuman RJ, Kramer J, Kuperman S, Hesselbrock V, Reich T, Bucholz KK. Are There Subgroups of Bulimia Nervosa Based on Comorbid Psychiatric Disorders? Int J Eat Disord 2005; 37:19-25. (pdf file)

Dunn G, Hinrichs A, Bertelsen S, Jin C, Kauwe J, Suarez B, Bierut L. Microsatellites Versus Single-nucleotide Polymorphisms in Linkage Analysis for Quantitative and Qualitative Measures. BMC Genet 2005; 6 Suppl 1:S122. (pdf file)

Edenberg, H.J., Bierut, L.J., Boyce, P., Cao, M., Cawley, S., Chiles, R., Doheny, K.F., Hansen, M., Hinrichs, T., Jones, K., Kelleher, M., Kennedy, G.C., Liu, G., Marcus, G., McBride, C., Murray, S.S., Oliphant, A., Pettengill, J., Porjesz, B., Pugh, E.W., Rice, J.P., Rubano, T., Shannon, S., Steeke, R., Tischfield, J.A., Tsai, Y.Y., Zhang, C., and Begleiter, H. (2005).
Description of the data from the Collaborative Study on the Genetics of Alcoholism (COGA) and single-nucleotide polymorphism genotyping for Genetic Analysis Workshop 14.
BMC Genetics 6(Supplement 1):S2. (pdf file)

Eng M, Schuckit M, Smith T. The Level of Response to Alcohol in Daughters of Alcoholics and Controls. Drug Alcohol Depend 2005; 79:83-93. (pdf file)

Hesselbrock V, Higuchi S, Soyka M. Recent Developments in the Genetics of Alcohol-related Phenotypes. Alcohol Clin Exp Res 2005; 29(7):1321-1324. (pdf file)

Hinrichs A, Bertelsen S, Bierut L, Dunn G, Jin C, Kauwe J, Suarez B. Multipoint Identity-by-descent Computations for Single-point Polymorphism and Microsatellite Maps. BMC Genet 2005; 6 Suppl 1:S34. (pdf file)

Hinrichs A, Suarez B. Genotyping Errors, Pedigree Errors, and Missing Data. Genet Epidemol 2005; 29 Suppl 1:S120-S124. (pdf file)

Kamarajan, C., Porjesz, B., Jones, K.A., Choi, K., Chorlian, D.B., Padmanabhapillai, A., Rangaswamy, M., Stimus, A.T., and Begleiter, H. (2005).
Alcoholism is a disinhibitory disorder: neurophysiological evidence from a Go/No-Go task.
Biological Psychology 69:353-373. (pdf file)

Kamarajan, C., Porjesz, B., Jones, K.A., Chorlian, D.B., Padmanabhapillai, A., Rangaswamy, M., Stimus, A.T., and Begleiter, H. (2005).
Spatial-anatomical mapping of NoGo-P3 in the offspring of alcoholics: evidence of cognitive and neural disinhibition as a risk for alcoholism.
Clinical Neurophysiology 116:1049-1061. (pdf file)

Kauwe J, Bertelsen S, Bierut L, Dunn G, Hinrichs A, Jin C, Suarez B. The Efficacy of Short Tandem Repeat Polymorphisms Versus Single-nucleotide Polymorphisms for Resolving Population Structure. BMC Genet 2005; 6 Suppl 1:S84. (pdf file)

Kuperman S, Chan G, Kramer J, Bierut L, Bucholz K, Fox L, Hesselbrock V, Nurnberger Jr., J, Reich T, Reich W, Schuckit M. Relationship of Age of First Drink to Child Behavioral Problems and Family Psychopathology. Alcohol Clin Exp Res 2005; 29(10):1869-1876. (pdf file)

Ohannessian C, Hesselbrock V, Kramer J, Kuperman S, Bucholz K, Schuckit M, Nurnberger Jr., J. The Relationship Between Parental Psychopatholgoy and adolescent Psychopathology: An Examination of Gender Patterns. J Emot Behav Disord 2005; 13(2):67-76.

Porjesz, B., Rangaswamy, M., Kamarajan, C., Jones, K.A., Padmanabhapillai, A., and Begleiter, H. (2005).
The utility of neurophysiological markers in the study of alcoholism.
Clinical Neurophysiology 116:993-1018. (pdf file)

Rice J, Saccone S. (2005).

Alcoholism and Related Traits: A Summary of Group 13 Contributions (GAW).

Genet Epidemiol 29 Suppl 1:S96-S102. (pdf file)

Saccone S, Saccone N, Neuman R, Rice J. Genetic Analysis of the Maximum Drinks Phenotype. BMC Genet 2005; 6 Suppl 1:S124. (pdf file)

Schuckit MA, Smith TL, Danko G, Anderson K, Brown S, Kuperman S, Kramer J, Hesselbrock V, Bucholz K. (2005).

Evaluation of a Level of Response to Alcohol Based Structural Equation Model in Adolescents.

J Stud Alcohol 66:174-184. (pdf file)

Schuckit MA, Smith TL, Danko G, Kramer J, Godinez K, , Bucholz K, Nurnberger Jr., J, Hesselbrock V. (2005).

Prospective Evaluation of the Four DSM-IV Criteria for Alcohol Abuse in a Larger Population.

Am J Psychiatry 162(2):350-360. (pdf file)

Schuckit MA, Smith TL, Danko G, Kuperman S, Bierut LJ, Hesselbrock V. (2005).

Correlations Among First-Degree Relatives for Responses on the Self-Rating of the Effects of Alcohol (SRE) Questionnaire in Teenagers*.

J Stud Alcohol 66: 62-65. (pdf file)

Suarez B, Taylor C, Bertelsen S, Bierut L, Dunn G, Jin C, Kauwe J, Paterson A, Hinrichs A. An Analysis of Identical Single-nucleotide Polymorphisms Genotyped By Two Different Platforms. BMC Genet 2005; 6 Suppl 1:S152. (pdf file)

2004

Bierut, L.J., Rice, J.P., Goate, A., Hinrichs, A.L., Saccone, N.L., Foroud, T., Edenberg, H.J., Cloninger, C.R., Begleiter, H., Conneally, P.M., Crowe, R.R., Hesselbrock, V., Li, T.K., Nurnberger, J.I., Jr., Porjesz, B., Schuckit, M.A., and Reich, T. (2004).
A genomic scan for habitual smoking in families of alcoholics: Common and specific genetic factors in substance dependence.
American Journal of Medical Genetics 124A:19-27. (pdf file)

Dick, D.M., Edenberg, H.J., Xuei, X., Goate, A., Kuperman, S., Schuckit, M., Crowe, R., Smith, T.L., Porjesz, B., Begleiter, H., and Foroud, T. (2004).
Association of GABRG3 with alcohol dependence.
Alcoholism: Clinical and Experimental Research 28:4-9. (pdf file)

Dick, D.M., Li, T.K., Edenberg, H.J., Hesselbrock, V., Kramer, J., Kuperman, S., Porjesz, B., Bucholz, K., Goate, A., Nurnberger, J., and Foroud, T. (2004).
A genome-wide screen for genes influencing conduct disorder.
Molecular Psychiatry 9:81-86. (pdf file)

Edenberg, H.J., Dick, D.M., Xuei, X., Tian, H., Almasy, L., Bauer, L.O., Crowe, R.R., Goate, A., Hesselbrock, V., Jones, K., Kwon, J., Li, T.K., Nurnberger, J.I., Jr., O'Connor, S.J., Reich, T., Rice, J., Schuckit, M.A., Porjesz, B., Foroud, T., and Begleiter, H. (2004).
Variations in GABRA2, encoding the alpha 2 subunit of the GABAA receptor, are associated with alcohol dependence and with brain oscillations.
American Journal of Human Genetics 74:705-714. (pdf file)

Hesselbrock V, Dick D, Hesselbrock M, Foroud T, Schuckit M, Edenberg H, Bucholz K, Kramer J, Reich T, Goate A, Bierut L, Rice J, Nurnberger Jr. J. The Search for Genetic Risk Factors Associated with Suicidal Behavior. Alcohol Clin Exp Res 2004; 28(5):70S-76S.

Jones, K.A., Porjesz, B., Almasy, L., Bierut, L., Goate, A., Wang, J.C., Dick, D.M., Hinrichs, A., Kwon, J., Rice, J.P., Rohrbaugh, J., Stock, H., Wu, W., Bauer, L.O., Chorlian, D.B., Crowe, R.R., Edenberg, H.J., Foroud, T., Hesselbrock, V., Kuperman, S., Nurnberger Jr, J., O'Connor, S.J., Schuckit, M.A., Stimus, A.T., Tischfield, J.A., Reich, T., and Begleiter, H. (2004).
Linkage and linkage disequilibrium of evoked EEG oscillations with CHRM2 receptor gene polymorphisms: implications for human brain dynamics and cognition.
International Journal of Psychophysiology 53:75-90. (pdf file)

Kamarajan, C., Porjesz, B., Jones, K.A., Choi, K., Chorlian, D.B., Padmanabhapillai, A., Rangaswamy, M., Stimus, A.T., and Begleiter, H. (2004).
The role of brain oscillations as functional correlates of cognitive systems: a study of frontal inhibitory control in alcoholism.
International Journal of Psychophysiology 51:155-180. (pdf file)

Nurnberger, J.I., Jr., Wiegand, R., Bucholz, K., O'Connor, S., Meyer, E.T., Reich, T., Rice, J., Schuckit, M., King, L., Petti, T., Bierut, L., Hinrichs, A.L., Kuperman, S., Hesselbrock, V., Porjesz, B. (2004).
A family study of alcohol dependence: coaggregation of multiple disorders in relatives of alcohol-dependent probands.
Archives of General Psychiatry 61:1246-56. (pdf file)

Ohannessian C, Hesselbrock V, Kramer J, Bucholz K, Schuckit M, Kuperman S, Nurnberger Jr. J. (2004).

Parental Substance Use Consequences and Adolescent Psychopathology.

J Stud Alcohol 2004; 65(6):725-730. (pdf file)

Ohannessian C, Hesselbrock V, Kramer J, Kuperman S, Bucholz K, Schuckit M, Nurnberger Jr., J. The Relationship Between Parental Alcoholism and Adolescent Psychopathology: A Systematic Examination of Parental Comorbid Psychopathology. J Abnorm Child Psychol 2004; 32(5):519-533. (pdf file)

Polich J, Ochoa CJ.

Alcoholism Risk, Tobacco Smoking, and P300 Event-related Potential.

Clin Neurophysiol 2004; 115:1374-1383. (pdf file)

Porjesz, B., Jones, K., and Begleiter, H. (2004).
The genetics of oscillations in the human brain.
In: Hallett, M., Phillips II, L.H., Schomer, D.L., Massey, J.M. (eds.), Advances in Clinical Neurophysiology (Supplements to Clinical Neurophysiology, Volume 57). Elsevier B.V., The Netherlands, 437-445. (pdf file)

Rangaswamy, M., Porjesz, B., Ardekani, B.A., Choi, S.J., Tanabe, J.L., Lim, K.O., and Begleiter, H. (2004).
A functional MRI study of visual oddball: evidence for frontoparietal dysfunction in subjects at risk for alcoholism.
Neuroimage 21:329-339. (pdf file)

Rangaswamy, M., Porjesz, B., Chorlian, D.B., Wang, K., Jones, K.A., Kuperman, S., Rohrbaugh, J., O'Connor, S.J., Bauer, L.O., Reich, T., and Begleiter, H. (2004).
Resting EEG in offspring of male alcoholics: beta frequencies.
International Journal of Psychophysiology 51:239-251. (pdf file)

Wang, J.C., Hinrichs, A.L., Stock, H., Budde, J., Allen, R., Bertelsen, S., Kwon, J.M., Wu, W., Dick, D.M., Rice, J., Jones, K., Nurnberger, J.I., Jr., Tischfield, J., Porjesz, B., Edenberg, H.J., Hesselbrock, V., Crowe, R., Schuckit, M., Begleiter, H., Reich, T., Goate, A.M., and Bierut, L.J. (2004).
Evidence of common and specific genetic effects: association of the muscarinic acetylcholine receptor M2 (CHRM2) gene with alcohol dependence and major depressive syndrome.
Human Molecular Genetics 13:1903-1911. (pdf file)

2003

Almasy, L. (2003).
Quantitative risk factors as indicies of alcoholism susceptibility.
Annals of Medicine 35:337-343. (pdf file)

Chorlian, D.B., Porjesz, B., and Begleiter, H. (2003).
Determination of human EEG alpha entrainment ERD/ERS using the continuous complex wavelet transform.
Proceedings of SPIE 5102:145-55. (pdf file)

Dick DM, Foroud T. Candidate Genes for Alcohol Dependence: A Review of Genetic Evidence from Human Studies. Alcohol Clin Exp Res 2003; 27(5):868-879. (pdf file)

Foroud T, Nurnberger Jr. J. Genetics of Addictive Disorders. In: Soares J & Gershon S (eds.), The Handbook of Medical Psychiatry, NY, Marcel Dekker, Inc. 2003; Series Volume 20.

Ghosh, S., Begleiter, H., Porjesz, B., Chorlian, D.B., Edenberg, H.J., Foroud, T., Goate, A., and Reich, T. (2003).
Linkage Mapping of Beta 2 EEG Waves via Non-Parametric Regression.
American Journal of Medical Genetics 118B:66-71. (pdf file)

Hesselbrock MN, Hesselbrock VM, Segal B, Schuckit MA, Bucholz K. Ethnicity and Psychiatric Co-morbidity Among Alcohol Dependent Persons Who Receive Inpatient Treatment: African Americans, Alaska Natives & Caucasians and Hispanics. Alcohol Clin Exp Res 2003; 27(8): 1368-1373. (pdf file)

Hesselbrock VM, Hesselbrock MN, Segal B. Alcohol Dependence Among Alaskan Natives and their Health Care Utilization. Alcohol Clin Exp Res 2003; 27(8): 1353-1355. (pdf file)

Porjesz, B. and Begleiter, H. (2003).
Alcoholism and human electrophysiology.
Alcohol Research & Health 27:153-160. (pdf file)

Preuss UW, Schuckit MA, Smith TL, Danko GP, Bucholz KK, Hesselbrock MN, Hesselbrock V, Kramer JR. Predictors and Correlates of Suicide Attempts Over 5 Years in 1,237 Alcohol-Dependent Men and Women. Am J Psychiatry 2003; 160:56-63. (pdf file)

Rangaswamy, M., Porjesz, B., Chorlian, D.B., Choi, K., Jones, K.A., Wang, K., Rohrbaugh, J., O'Connor, S., Kuperman, S., Reich, T., and Begleiter, H. (2003).
Theta power in the EEG of alcoholics.
Alcoholism: Clinical and Experimental Research 27:607-615. (pdf file)

Rice JP, Neuman RJ, Saccone NL, Corbett J, Rochberg N, Hesselbrock V, Bucholz KK, McGuffin P, Reich T. Age and Birth Cohort Effects on Rates of Alcohol Dependence. Alcohol Clin Exp Res 2003; 27(1):93-99. (pdf file)

Rice JP, Saccone NL, Foroud T, Edenberg HJ, Nurnberger Jr. JI, Goate A, Crowe RR, Hesselbrock V, Schuckit M, Porjesz B, Reich T, Begleiter H. Alcoholism: the USA Collaborative Study on the Genetics of Alcoholism (COGA). In: Encyclopedia of the Human Genome. Macmillian Publishers Ltd, Nature Publishing Group 2003.

Schuckit M, Danko G, Smith T, Hesselbrock V, Kramer J, Bucholz K. A Five-Year Prospective Evaluation of DSM-IV Alcohol Dependence With and Without a Physiological Component. Alcohol Clin Exp Res 2003; 27:818-825. (pdf file)

Song, J., Koller, D.L., Foroud, T., Carr, K., Zhao, J., Rice, J., Nurnberger, J.I., Jr., Begleiter, H., Porjesz, B., Smith, T.L., Schuckit, M.A., and Edenberg, H.J. (2003).
Association of GABAA receptors and alcohol dependence and the effects of genetic imprinting.
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics 117B:39-45. (pdf file)

Suresh, S., Porjesz, B., Chorlian, D.B., Choi, K., Jones, K.A., Wang, K., Stimus, A., and Begleiter, H. (2003).
Auditory P3 in Female Alcoholics.
Alcoholism: Clinical and Experimental Research 27:1064-1074. (pdf file)

Wilhelmsen KC, Schuckit M, Smith TL, Lee JV, Segall SK, Feiler HS, Kalmijn J. A Search for Genes Related to a Low-Level Response to Alcohol as Established by an Alcohol Challenge. Alcohol Clin Exp Res 2003; 27(7):1041-1047. (pdf file)

2002

Ardekani, B.A., Choi, S.J., Hossein-Zadeh, G.A., Porjesz, B., Tanabe, J.L., Lim, K.O., Bilder, R., Helpern, J.A., and Begleiter, H. (2002).
Functional magnetic resonance imaging of brain activity in the visual oddball task.
Cognitive Brain Research 14:347-356. (pdf file)

Bierut, L.J., Saccone, N.L., Rice, J.P., Goate, A., Foroud, T., Edenberg, H., Almasy, L., Conneally, P.M., Crowe, R., Hesselbrock, V., Li, T.K., Nurnberger, J., Jr., Porjesz, B., Schuckit, M.A., Tischfield, J., Begleiter, H., and Reich, T. (2002).
Defining alcohol-related phenotypes in humans. The Collaborative Study on the Genetics of Alcoholism.
Alcohol Research & Health 26:208-213. (pdf file)

Cohen, H.L., Ji, J., Chorlian, D.B., Begleiter, H., and Porjesz, B. (2002).
Alcohol-related ERP changes recorded from different modalities: a topographic analysis.
Alcoholism: Clinical and Experimental Research 26:303-317. (pdf file)

Dick DM, Foroud T. Genetic Strategies to Detect Genes Involved in Alcoholism and Alcohol-Related Traits. Alcohol Res Health 2002; 26(3):172-180. Click here to view paper on publisher's site.

Dick, D.M., Nurnberger, J., Jr., Edenberg, H.J., Goate, A., Crowe, R., Rice, J., Bucholz, K.K., Kramer, J., Schuckit, M.A., Smith, T.L., Porjesz, B., Begleiter, H., Hesselbrock, V., and Foroud, T. (2002).
Suggestive linkage on chromosome 1 for a quantitative alcohol-related phenotype.
Alcoholism: Clinical and Experimental Research 26:1453-1460. (pdf file)

Edenberg HJ. The Collaborative Study on the Genetics of Alcoholism: An Update. Alcohol Res Health 2002; 26(3):214-218. Click here to view paper on publisher's site.

Foroud T, Berrettini WH. Addictive Disorders. In: Principles and Practice of Medical Genetics, Editors: DL Rimoin, JM Connor, RE Pyeritz & BR Korf, 2002 Churchill Livingstone, 4th Ed. London: Harcourt Brace. pp. 2949-2971.

Hesselbrock V, Mitsuru K. COGA. Bunshi-Seichin Igaku Journal of Molecular Psychiatry 2002; 2:1.

Jones, K., Begleiter, H., Porjesz, B., Wang, K., and Chorlian, D. (2002).
Complexity measures of event related potential surface Laplacian data calculated using the wavelet packet transform.
Brain Topography 14:333-344. (pdf file)

Nurnberger Jr. JI, Foroud T, Flury L, Meyer ET, Wiegand R. Is There a Genetic Relationship Between Alcoholism and Depression? Alcohol Res Health 2002; 26(3):233-240. Click here to view paper on publisher's site.

Porjesz, B., Almasy, L., Edenberg, H.J., Wang, K., Chorlian, D.B., Foroud, T., Goate, A., Rice, J.P., O'Connor, S.J., Rohrbaugh, J., Kuperman, S., Bauer, L.O., Crowe, R.R., Schuckit, M.A., Hesselbrock, V., Conneally, P.M., Tischfield, J.A., Li, T.K., Reich, T., and Begleiter, H. (2002).
Linkage disequilibrium between the beta frequency of the human EEG and a GABAA receptor gene locus.
Proceedings of the National Academy of Sciences of the United States of America 99:3729-3733. (pdf file)

Porjesz, B., Begleiter, H., Wang, K., Almasy, L., Chorlian, D.B., Stimus, A.T., Kuperman, S., O'Connor, S.J., Rohrbaugh, J., Bauer, L.O., Edenberg, H.J., Goate, A., Rice, J.P., and Reich, T. (2002).
Linkage and linkage disequilibrium mapping of ERP and EEG phenotypes.
Biological Psychology 61:229-248. (pdf file)

Preuss UW, Schuckit MA, Smith TL, Danko GP, Buckman K, Bierut L, Bucholz KK, Hesselbrock, Hesselbrock VM, Reich T. Comparison of 3190 Alcohol-Dependent Individuals With and Without Suicide Attempts. Alcohol Clin Exp Res 2002; 26(4):471-477.

Preuss UW, Schuckit MA, Smith TL, Danko GP, Dasher AC, Hesselbrock MN, Hesselbrock VM, Nurnberger, Jr. JI. A Comparison of Alcohol-Induced and Independent Depression in Alcoholics with Histories of Suicide Attempts*. J Stud Alcohol 2002; 63:498-502.

Rangaswamy, M., Porjesz, B., Chorlian, D.B., Wang, K., Jones, K.A., Bauer, L.O., Rohrbaugh, J., O'Connor, S.J., Kuperman, S., Reich, T., and Begleiter, H. (2002).
Beta power in the EEG of alcoholics.
Biological Psychiatry 52:831-842. (pdf file)

Saccone NL, Rice JP, Rochberg N, Williams JT, Goate A, Reich T, Edenberg HJ, Foroud T, Nurnberger Jr., JI, Bierut LJ, Crowe R, Li T-K. Linkage for Platelet Monomine Oxidase (MAO) Activity: Results from a Replication Sample. Alcohol Clin Exp Res 2002; 26(5):603-609. (pdf file)

Schuckit MA, Danko GP, Smith TL, Buckman KR. The Five-Year Predictive Validity of Each of the Seven DSM-IV Items for Alcohol Dependence Among Alcoholics. Alcohol Clin Exp Res 2002; 26(7):980-987. (pdf file)

Schuckit MA, Smith TL, Danko GP, Reich T, Bucholz KK, Bierut LJ. Similarities in the Clinical Characteristics Related to Alcohol Dependence in Two Populations. Am J Addict 2002; 11:1-9.

Schuckit MA, Smith TL, Kramer J, Danko G, Volpe FR. The Prevalence and Clinical Course of Sedative-Hypnotic Abuse and Dependence in a Large Cohort. Am J Drug Alcohol Abuse 2002; 28(1):73-90.

2001

Almasy, L., Porjesz, B., Blangero, J., Goate, A., Edenberg, H.J., Chorlian, D.B., Kuperman, S., O'Connor, S.J., Rohrbaugh, J., Bauer, L.O., Foroud, T., Rice, J.P., Reich, T., and Begleiter, H. (2001).
Genetics of event-related brain potentials in response to a semantic priming paradigm in families with a history of alcoholism.
American Journal of Human Genetics 68:128-135. (pdf file)

Daw EW, Rice JP, Anthenelli RM, Schuckit MA, Tipp J, Saccone NL, Reich T, Nurnberger, Jr. JI, Li T-K. A Bootstrapped Commingling Analysis of Platelet Monoamine Oxidase Activity Levels Corrected of Cigarette Smoking. Psychiatr Genet 2001; 11(4):177-185.

Dick D, Nurnberger Jr. J, Edenberg H, Goate A, Crowe R, Rice J, Hesselbrock V, Foroud T. Suggestive Linkage on Chromosomes 1 and 15 for a Protective Alcohol-related Phenotype. Am J Hum Genet 2001; 69(4) Suppl:530 (#2042).

Hada, M., Porjesz, B., Chorlian, D.B., Begleiter, H., and Polich, J. (2001).
Auditory P3a deficits in male subjects at high risk for alcoholism.
Biological Psychiatry 49:726-738. (pdf file)

Hesselbrock, V., Begleiter, H., Porjesz, B., O'Connor, S., and Bauer, L. (2001).
P300 event-related potential amplitude as an endophenotype of alcoholism-evidence from the collaborative study on the genetics of alcoholism.
Journal of Biomedical Science 8:77-82. (pdf file)

Hesselbrock VM, Foroud T, Edenberg H, Nurnberger Jr. JI, Reich T, Rice JP. Genetics and Alcoholism: The COGA Project. In: Alcohol in Health and Disease, Editors: DP Agaarwal & HK Seitz, 2001 Marcel Dekker, Inc., New York, pp. 103-124.

Kuperman S, Schlosser SS, Kramer JR, Bucholz K, Hesselbrock V, Reich T, Reich W. Developmental Sequence From Disruptive Behavior Diagnosis to Adolescent Alcohol Dependence. Am J Psychiatry 2001; 158:2022-2026.

Kuperman S, Schlosser SS, Kramer JR, Bucholz K, Hesselbrock V, Reich T, Reich W. Risk Domains Associated With an Adolescent Alcohol Dependence Diagnosis. Addiction 2001; 96:629-636. (pdf file)

Nurnberger Jr. JI, Foroud T, Flury L, Su J, Meyer ET, Hu K, Crowe R, Edenberg H, Goate A, Bierut L, Reich T, Schuckit M, Reich W. Evidence for a Locus on Chromosome 1 That Influences Vulnerability to Alcoholism and Affective Disorder. Am J Psychiatry 2001; 158:718-724. (pdf file)

Prabhu, V.R., Porjesz, B., Chorlian, D.B., Wang, K., Stimus, A., and Begleiter, H. (2001).
Visual P3 in female alcoholics.
Alcoholism: Clinical and Experimental Research 25:531-539. (pdf file)

Schuckit M, Danko GP, Raimo EB, Smith TL, Eng MY, Carpenter KKT, Hesselbrock VM. A Preliminary Evaluation of the Potential Usefulness of the Diagnoses of Polysubstance Dependence. J Stud Alcohol 2001; 62:54-61.

Schuckit MA, Edenberg HJ, Kalmijn J, Flury L, Smith TL, Reich T, Bierut L, Goate A, Foroud T. A Genome-Wide Search for Genes That Relate to a Low Level of Response to Alcohol. Alcohol Clin Exp Res 2001; 25(3):323-329. (pdf file)

Schuckit MA, Smith TL, Danko GP, Bucholz KK, Reich T, Bierut L. Five-Year Clinical Course Associated With DSM-IV Alcohol Abuse or Dependence in a Large Group of Men and Women. Am J Psychiatry 2001; 158(7):1084-1090. (pdf file)

Vedeniapin AB, Anokhin AP, Sirevaag E, Rohrbaugh JW, Cloninger CR. Visual P300 and the self-directed scale of the Temperament and Character Inventory. Psychiatry Res 2001; 101:145-156.

Wang, K., Begleiter, H., and Porjesz, B. (2001).
Warp-averaging event-related potentials.
Clinical Neurophysiology 112:1917-1924. (pdf file)

Zhang, X.L., Cohen, H.L., Porjesz, B., and Begleiter, H. (2001).
Mismatch negativity in subjects at high risk for alcoholism.
Alcoholism: Clinical and Experimental Research 25:330-337. (pdf file)

2000

Anokhin, A.P., Vedeniapin, A.B., Sirevaag, E.J., Bauer, L.O., O'Connor, S.J., Kuperman, S., Porjesz, B., Reich, T., Begleiter, H., Polich, J., and Rohrbaugh, J.W. (2000).
The P300 brain potential is reduced in smokers.
Psychopharmacology 149:409-413. (pdf file)

Begleiter, H. and Porjesz, B. (2000).
What is inherited in the predisposition to alcoholism: New model or more muddle?.
Alcoholism: Clinical and Experimental Research 24:246-250. (pdf file)

Bierut, L.J., Rice, J.P., Edenberg, H.J., Goate, A., Foroud, T., Cloninger, C.R., Begleiter, H., Conneally, P.M., Crowe, R.R., Hesselbrock, V., Li, T.K., Nurnberger, J.I., Jr., Porjesz, B., Schuckit, M.A., and Reich, T. (2000).
Family-based study of the association of the dopamine D2 receptor gene (DRD2) with habitual smoking.
American Journal of Medical Genetics 90:299-302. (pdf file)

Bierut LJ, Schuckit MA, Hesselbrock V, Reich T. Co-Occurring Risk Factors for Alcohol Dependence and Habitual Smoking. Results From the Collaborative Study on the Genetics of Alcoholism. Alcohol Health Res World 2000; 24(4):233-241.

Bucholz K, Hesselbrock V, Heath A, Kramer J, Schuckit M. A Latent Class Analysis of Antisocial Personality Disorder Symptom Data from a Multi-Centre Family Study of Alcoholism. Addiction 2000; 95(4):553-567. (pdf file)

Costa, L., Bauer, L., Kuperman, S., Porjesz, B., O'Connor, S., Hesselbrock, V., Rohrbaugh, J., and Begleiter, H. (2000).
Frontal P300 decrements, alcohol dependence, and antisocial personality disorder.
Biological Psychiatry 47:1064-1071. (pdf file)

Daeppen JB, Smith T, Danko G, Gordon L, Landi N, Nurnberger Jr. JI, Bucholz K, Raimo E, Schuckit M. Clinical Correlates of Cigarette Smoking and Nicotine Dependence in Alcohol Dependent Men and Women. Alcohol Alcohol 2000; 35(2):171-175.

Foroud, T., Edenberg, H.J., Goate, A., Rice, J., Flury, L., Koller, D.L., Bierut, L.J., Conneally, P.M., Nurnberger, J.I., Bucholz, K.K., Li, T.K., Hesselbrock, V., Crowe, R., Schuckit, M., Porjesz, B., Begleiter, H., and Reich, T. (2000).
Alcoholism susceptibility loci: confirmation studies in a replicate sample and further mapping.
Alcoholism: Clinical and Experimental Research 24:933-945. (pdf file)

Hada, M., Porjesz, B., Begleiter, H., and Polich, J. (2000).
Auditory P3a assessment of male alcoholics.
Biological Psychiatry 48:276-286. (pdf file)

Hesselbrock V, Hesselbrock M, Bucholz K, Schuckit M, Begleiter H, Porjesz B, Nurnberger Jr. J, Reich T. A Five Cluster Phenotype of Alcohol Dependence. Alcohol Clin Exp Res 2000; 24(5):163A.

McClintick J, Edenberg HJ. BlastReport: A Perl Script to Facilitate the Use of Sequence Databases for Mapping and Clustering. Biotechniques 2000; 29(6):1272-1276.

Raimo EB, Smith TL, Danko GP, Bucholz KK, Schuckit MA. Clinical Characteristics and Family Histories of Alcoholics with Stimulant Dependence. J Stud Alcohol 2000; 61:728-735.

Saccone, N.L., Kwon, J.M., Corbett, J., Goate, A., Rochberg, N., Edenberg, H.J., Foroud, T., Li, T.K., Begleiter, H., Reich, T., and Rice, J.P. (2000).
A genome screen of maximum number of drinks as an alcoholism phenotype.
American Journal of Medical Genetics 96:632-637. (pdf file)

Schuckit MA, Smith TL, Kalmijn J, Tsuang J, Hesselbrock V, Bucholz KK. Response to Alcohol in Daughters of Alcoholics: A Pilot Study and a Comparison with Sons of Alcoholics. Alcohol Alcohol 2000; 35(3):242-248.

Taber, K.H., Hurley, R.A., Abi-Dargham, A., and Porjesz (2000).
Cortical Inhibition in Alcohol Dependence.
Journal of Neuropsychiatry and Clinical Neurosciences 12:173 - 176. (pdf file)

Wang, K., Begleiter, H., and Porjesz, B. (2000).
Trilinear modeling of event-related potentials.
Brain Topography 12:263-271. (pdf file)

1999

Almasy, L., Porjesz, B., Blangero, J., Chorlian, D.B., O'Connor, S.J., Kuperman, S., Rohrbaugh, J., Bauer, L.O., Reich, T., Polich, J., and Begleiter, H. (1999).
Heritability of event-related brain potentials in families with a history of alcoholism.
American Journal of Medical Genetics 88:383-390. (pdf file)

Begleiter, H. and Porjesz, B. (1999).
What is inherited in the predisposition toward alcoholism? A proposed model.
Alcoholism: Clinical and Experimental Research 23:1125-1135. (pdf file)

Begleiter, H., Reich, T., Nurnberger, J., Jr., Li, T.K., Conneally, P.M., Edenberg, H., Crowe, R., Kuperman, S., Schuckit, M., Bloom, F., Hesselbrock, V., Porjesz, B., Cloninger, C.R., Rice, J., and Goate, A. (1999).
Description of the Genetic Analysis Workshop 11 Collaborative Study on the Genetics of Alcoholism.
Genetic Epidemiology 17 (Suppl 1):S25-S30. (pdf file)

Foroud T, Li T-K. Genetics of Alcoholism: A Review of Recent Studies in Human and Animal Models. Am J Addict 1999; 8:261-278.

Hesselbrock M, Easton C, Bucholz K, Schuckit M, Hesselbrock V. A Validity Study of the SSAGA - A Comparison With the SCAN. Addiction 1999; 94(9):1361-1370. (pdf file)

Holguin, S.R., Porjesz, B., Chorlian, D.B., Polich, J., and Begleiter, H. (1999).
Visual P3a in male subjects at high risk for alcoholism.
Biological Psychiatry 46:281-291. (pdf file)

Holguin, S.R., Porjesz, B., Chorlian, D.B., Polich, J., and Begleiter, H. (1999).
Visual P3a in male alcoholics and controls.
Alcoholism: Clinical and Experimental Research 23:582-591. (pdf file)

Holguin S, Porjesz B, Chorlian D, Polich J, Begleiter H. Visual P3a in Male Subjects at High Risk for Alcoholism. Biol Psychiatry 1999; 46:281-291. (pdf file)

Ji, J., Porjesz, B., and Begleiter, H. (1999).
Event-related potential index of semantic mnemonic dysfunction in abstinent alcoholics.
Biological Psychiatry 45:494-507. (pdf file)

Ji, J., Porjesz, B., Begleiter, H., and Chorlian, D. (1999).
P300: the similarities and differences in the scalp distribution of visual and auditory modality.
Brain Topography 11:315-327. (pdf file)

Kuperman S, Schlosser S, Lidral J, Reich W. Relationship of Child Psychopathology to Parental Alcoholism and ASPD. J Am Acad Child Adolesc Psychiatry 1999; 38:6.

Neuman, R.J., Todd, R.D., Heath, A.C., Reich, W., Hudziak, J.J., Bucholz, K.K., Madden, P.A., Begleiter, H., Porjesz, B., Kuperman, S., Hesselbrock, V., and Reich, T. (1999).
Evaluation of ADHD typology in three contrasting samples: a latent class approach.
Journal of the American Academy of Child and Adolescent Psychiatry 38:25-33. (pdf file)

Polich J, Bloom F. P300, Alcoholism Inheritability, and Stimulus Modality. Alcohol 1999; 17:149-156. (pdf file)

Raimo EB, Daeppen JB, Smith TL, Danko GP, Schuckit MA. Clinical Charateristics of Alcoholism in Alcohol-Dependent Subjects With and Without History of Alcohol Treatment. Alcohol Clin Exp Res 1999; 23(10):1605-1613. Download PDF (abstract only)

Reich T, Hinrichs A, Culverhouse R, Bierut L. Psychiatric Genetics '99 - Genetic Studies of Alcoholism and Substance Dependence. Am J Hum Genet 1999; 65:599-605.

Saccone NL, Rice JP, Rochberg N, Goate A, Reich T, Shears S, Wu W, Nurnberger Jr. JI, Foroud T, Edenberg HJ, Li T-K. A Genome Screen for Platelet Monoamine Oxidase (MAO) Activity. Am J Med Genet B Neuropsychiatr Genet 1999; 88:517-521.

Schuckit M. New Findings in the Genetics of Alcoholism. J Am Med Assoc 1999; 281(20):1875-1876.

Schuckit MA, Daeppen J-B, Danko GP, Tripp ML, Smith TL, Li T-K, Hesselbrock VM, Bucholz KK. Clinical Implications for Four Drugs of the DSM-IV Distinction Between Substance Dependence With and Without a Physiological Component. Am J Psychiatry 1999; 156(1):41-49. (pdf file)

Stassen, H.H., Begleiter, H., Porjesz, B., Rice, J., Scharfetter, C., and Reich, T. (1999).
Structural decomposition of genetic diversity in families with alcoholism.
Genetic Epidemiology 17 Suppl 1:S325-330. (pdf file)

Wang, K. and Begleiter, H. (1999).
Local polynomial estimate of surface Laplacian.
Brain Topography 12:19-29. (pdf file)

Williams, J.T., Begleiter, H., Porjesz, B., Edenberg, H.J., Foroud, T., Reich, T., Goate, A., Van Eerdewegh, P., Almasy, L., and Blangero, J. (1999).
Joint multipoint linkage analysis of multivariate qualitative and quantitative traits. II. Alcoholism and event-related potentials.
American Journal of Human Genetics 65:1148-1160. (pdf file)

1998

Almasy L, Williams J, Porjesz B, Reich T, Blangero J, Begleiter H. Pleiotropic Genetic Influences on Event-Related Brain Potentials and Alcoholism. Am J Med Genet 1998; 81:495-496.

Anokhin A, Rohrbaugh J. Frontal EEG Asymmetry in Families. Psychophysiology 1998; 35 Suppl:517.

Anthenelli RM, Tipp J, Li T-K, Magnes L, Schuckit MA, Rice J, Daw W, Nurnberger Jr. J. Platelet Monoamine Oxidase Activity in Subgroups of Alcoholics and Controls: Results from the Collaborative Study on the Genetics of Alcoholism. Alcohol Clin Exp Res 1998; 22/3:598-604. Download PDF (abstract only)

Begleiter, H., Porjesz, B., Reich, T., Edenberg, H.J., Goate, A., Blangero, J., Almasy, L., Foroud, T., Van Eerdewegh, P., Polich, J., Rohrbaugh, J., Kuperman, S., Bauer, L.O., O'Connor, S.J., Chorlian, D.B., Li, T.K., Conneally, P.M., Hesselbrock, V., Rice, J.P., Schuckit, M.A., Cloninger, R., Nurnberger, J., Jr., Crowe, R., and Bloom, F.E. (1998).
Quantitative trait loci analysis of human event-related brain potentials: P3 voltage.
Electroencephalography and Clinical Neurophysiology 108:244-250. (pdf file)

Bierut, L.J., Dinwiddie, S.H., Begleiter, H., Crowe, R.R., Hesselbrock, V., Nurnberger, J.I., Jr., Porjesz, B., Schuckit, M.A., and Reich, T. (1998).
Familial transmission of substance dependence: alcohol, marijuana, cocaine, and habitual smoking: a report from the Collaborative Study on the Genetics of Alcoholism.
Archives of General Psychiatry 55:982-988. (pdf file)

Blangero J. Quantitative Trait Locus Mapping Methods for Complex Phenotypes: The State-of-the-Science. Am J Med Genet 1998; 81:461.

Cloniger, C.R., Van Eerdewegh, P., Goate, A., Edenberg, H.J., Blangero, J., Hesselbrock, V., Reich, T., Nurnberger, J.I., Schuckit, M., Porjesz, B., Crowe, R., Rice, J.P., Foroud, T., Przybeck, T.R., Almasy, L., Buchholz, K., Wu, W., Shears, S., Carr, K., Crose, C., Willig, C., Zhou, J., Tischfield, J.A., Li, T.-K., Conneally, P.M., and Begleiter, H. (1998).
Anxiety Proneness linked to epistatic loci in genome scan of human personality traits.
American Journal of Medical Genetics 81:313-317. (pdf file)

Cohen, H.L., Porjesz, B., Stimus, A.T., and Begleiter, H. (1998).
Effects of ethanol on temporal recovery of auditory-evoked potentials in individuals at risk for alcoholism.
Alcoholism: Clinical and Experimental Research 22:945-953. (pdf file)

Edenberg, H.J., Foroud, T., Koller, D.L., Goate, A., Rice, J., Van Eerdewegh, P., Reich, T., Cloninger, C.R., Nurnberger, J.I., Jr., Kowalczuk, M., Wu, B., Li, T.K., Conneally, P.M., Tischfield, J.A., Wu, W., Shears, S., Crowe, R., Hesselbrock, V., Schuckit, M., Porjesz, B., and Begleiter, H. (1998).
A family-based analysis of the association of the dopamine D2 receptor (DRD2) with alcoholism.
Alcoholism: Clinical and Experimental Research 22:505-512. (pdf file)

Edenberg, H.J., Foroud, T., Koller, D.L., Goate, A., Rice, J., Van Eerdewegh, P., Reich, T., Cloninger, C.R., Nurnberger, J.I., Jr., Kowalczuk, M., Wu, B., Li, T.K., Conneally, P.M., Tischfield, J.A., Wu, W., Shears, S., Crowe, R., Hesselbrock, V., Schuckit, M., Porjesz, B., and Begleiter, H. (1998).
Letter to the editor, Science, in response to previously published letter to the editor by Dr. Ernest Noble, re: A family-based analysis of the association of the dopamine D2 receptor (DRD2) with alcoholism.
Science 282:1265. (pdf file)

Edenberg H, Reich T, Foroud T, Goate A, Rice J, Begleiter H. Genes Affecting Alcohol Dependence and Related Phenotypes: A Genomic Survey by the Collaborative Study on the Genetics of Alcoholism (COGA). Miami Nature Biology Short Reports 1998; 9:71-72.

Edenberg H, Reynolds J. Improved Method for Detecting the Long and Short Promoter Alleles of the Serotonin Transporter Gene HTT (SLC6A4). Psych Genet 1998; 8:193-195.

Edenberg, H.J., Reynolds, J., Koller, D.L., Begleiter, H., Bucholz, K.K., Conneally, P.M., Crowe, R., Goate, A., Hesselbrock, V., Li, T.K., Nurnberger, J.I., Jr., Porjesz, B., Reich, T., Rice, J.P., Schuckit, M., Tischfield, J.A., and Foroud, T. (1998).
A family-based analysis of whether the functional promoter alleles of the serotonin transporter gene HTT affect the risk for alcohol dependence.
Alcoholism: Clinical and Experimental Research 22:1080-1085. (pdf file)

Foroud, T., Bucholz, K.K., Edenberg, H.J., Goate, A., Neuman, R.J., Porjesz, B., Koller, D.L., Rice, J., Reich, T., Bierut, L.J., Cloninger, C.R., Nurnberger, J.I., Jr., Li, T.K., Conneally, P.M., Tischfield, J.A., Crowe, R., Hesselbrock, V., Schuckit, M., and Begleiter, H. (1998).
Linkage of an alcoholism-related severity phenotype to chromosome 16.
Alcoholism: Clinical and Experimental Research 22:2035-2042. (pdf file)

Goate A, Edenberg H. The Genetics of Alcoholism. In: Current Opinion in Genetics and Development, Eds. Kay Davies, Hunt Willard. 8:282-286.

Ji, J., Porjesz, B., and Begleiter, H. (1998).
ERP components in category matching tasks.
Electroencephalography and Clinical Neurophysiology 108:380-389. (pdf file)

Ji, J., Porjesz, B., Chorlian, D., and Begleiter, H. (1998).
Event-related potentials during digit recognition tasks.
Brain Research Cognitive Brain Research 7:179-190. (pdf file)

Porjesz, B. and Begleiter, H. (1998).
Genetic basis of event-related potentials and their relationship to alcoholism and alcohol use.
Journal of Clinical Neurophysiology 15:44-57. (pdf file)

Porjesz, B., Begleiter, H., Reich, T., Van Eerdewegh, P., Edenberg, H.J., Foroud, T., Goate, A., Litke, A., Chorlian, D.B., Stimus, A., Rice, J., Blangero, J., Almasy, L., Sorbell, J., Bauer, L.O., Kuperman, S., O'Connor, S.J., and Rohrbaugh, J. (1998).
Amplitude of visual P3 event-related potential as a phenotypic marker for a predisposition to alcoholism: preliminary results from the COGA Project. Collaborative Study on the Genetics of Alcoholism.
Alcoholism: Clinical and Experimental Research 22:1317-1323. (pdf file)

Reich, T., Edenberg, H.J., Goate, A., Williams, J.T., Rice, J.P., Van Eerdewegh, P., Foroud, T., Hesselbrock, V., Schuckit, M.A., Bucholz, K., Porjesz, B., Li, T.K., Conneally, P.M., Nurnberger, J.I., Jr., Tischfield, J.A., Crowe, R.R., Cloninger, C.R., Wu, W., Shears, S., Carr, K., Crose, C., Willig, C., and Begleiter, H. (1998).
Genome-wide search for genes affecting the risk for alcohol dependence.
American Journal of Medical Genetics 81:207-215. (pdf file)

Schuckit M, Daeppen J-B, Tipp J, Hesselbrock M, Bucholz K. The Clinical Course of Alcohol-Related Problems in Alcohol Dependent and Nonalcohol Dependent Drinking Women and Men. J Stud Alcohol 1998; 59:581-590.

Schuckit M, Smith T, Daeppen J-B, Eng M, Li T-K, Hesselbrock V, Nurnberger Jr. J, Bucholz K. The Clinical Relevance of the Distinction Between Alcohol Dependence With and Without a Physiological Component. Am J Psychiatry 1998; 155(6):733-740. (pdf file)

Vedeniapin AB, Anokhin A, Sirevaag E, Rohrbaugh J, Cloninger C. Personality Differences Between Smoking and Non-smoking Alcoholics. Alcohol Clin Exp Res 1998; 22:37A.

Wang, K., Begleiter, H., and Porjesz, B. (1998).
Spatial enhancement of event-related potentials using multiresolution analysis.
Brain Topography 10:191-200. (pdf file)

Wang, K., Begleiter, H., and Porjesz, B. (1998).
Analysis of repeated measurements in curves (brain potentials).
Proceedings of the Section of Statistics in Epidemiology of the American Statistical Association 122-127. (pdf file)

1997

Anokhin A, Vedeniapin A, Sirevaag E. Frontal EEG Asymmetry in Depression and Alchoholism: Effects of Comorbidity and Evidence for Genetic Influences. Behav Genet 1997; 27(6):583.

Blangero J, Almasy L, Williams J, Porjesz B, Reich T, Begleiter H. Incorporating Quantitative Traits in Genomic Scans of Psychiatric Diseases: Alcoholism and Event-Related Potentials. Am J Med Genet 1997; 74:602.

Cohen, H.L., Porjesz, B., Begleiter, H., and Wang, W. (1997).
Neurophysiological correlates of response production and inhibition in alcoholics.
Alcoholism: Clinical and Experimental Research 21:1398-1406. (pdf file)

Cohen, H.L., Porjesz, B., Begleiter, H., and Wang, W. (1997).
Neuroelectric correlates of response production and inhibition in individuals at risk to develop alcoholism.
Biological Psychiatry 42:57-67. (pdf file)

Crowe R, Kramer J, Hesselbrock V, Manos G, Bucholz K. The Utility of the "Brief MAST" and the "CAGE" in Identifying Alcohol Problems: Results from a National High-Risk and Low-Risk Sample. AMA Arch Fam Med 1997; 6:477-483.

Dinwiddie S. Characteristics of Injection Drug Users Derived from a Large Family Study of Alcoholism. Compr Psychiatry 1997; 38(4):218-229.

Koziol, J., Alexander, J., Bauer, L.O., Kuperman, S., Morzorati, O Connor, S.J., Porjesz, B., Stewart, P., and Begleiter, H. (1997).
A graphical technique for displaying correlation matrices.
The American Statistician 51:301-304. (pdf file)

Polich, J., Alexander, J., Kuperman, S., Morzorati, S., O'Connor, S.J., Porjesz, B., Rohrbaugh, J., and Begleiter, H. (1997).
P300 topography of amplitude/latency correlations.
Brain Topography 9:275-282. (pdf file)

Porjesz, B. and Begleiter, H. (1997).
Event-related potentials in COA's.
Alcohol Health and Research World 21:236-240. (pdf file)

Rohrbaugh, J.W., Dunham, D.N., Stewart, P.A., Bauer, L.O., Kuperman, S., O'Connor, S.J., Porjesz, B., and Begleiter, H. (1997).
Slow brain potentials in a visual-spatial memory task: topographic distribution and inter-laboratory consistency.
International Journal of Psychophysiology 25:111-122. (pdf file)

Schuckit M, Tipp J, Bergman M, Nurnberger Jr. J, Reich W, Hesselbrock V, Smith T. A Comparison of Induced and Independent Major Depressive Disorder in 2,945 Alcoholics. Am J Psychiatry 1997; 154(7):948-957. Download PDF (abstract only)

Schuckit M, Tipp J. Bucholz K, Nurnberger Jr. J, Hesselbrock V, Crowe R, Kramer J. The Lifetime Rates of Three Major Mood Disorders and Four Major Anxiety Disorders in Alcoholics and Controls. Addiction 1997; 92(10):1289-1304. (pdf file)

Schuckit M, Tipp J, Smith T, Bucholz K. Periods of Abstinence Following the Onset of Alcohol Dependence in 1,853 Men and Women. J Stud Alcohol 1997; 58:581-589.

Schuckit M, Smith T, Tipp J. The Self-Rating of the Effects of Alcohol (SRE) Form as a Retrospective Measure of the Risk For Alcoholism. Addiction 1997; 92(8):979-988. (pdf file)

Zhang, X.L., Begleiter, H., and Porjesz, B. (1997).
Do chronic alcoholics have intact implicit memory? An ERP study.
Electroencephalography and Clinical Neurophysiology 103:457-473. (pdf file)

Zhang, X.L., Begleiter, H., Porjesz, B., and Litke, A. (1997).
Electrophysiological evidence of memory impairment in alcoholic patients.
Biological Psychiatry 42:1157-1171. (pdf file)

Zhang, X.L., Begleiter, H., Porjesz, B., and Litke, A. (1997).
Reflection of working memory: ERP mnemonic effects.
Electroencephalography and Clinical Neurophysiology 104:546-554. (pdf file)

Zhang, X.L., Begleiter, H., Porjesz, B., and Litke, A. (1997).
Visual object priming differs from visual word priming: an ERP study.
Electroencephalography and Clinical Neurophysiology 102:200-215. (pdf file)

Zhang, X.L., Begleiter, H., and Porjesz, B. (1997).
Is working memory intact in alcoholics? An ERP study.
Psychiatry Research 75:75-89. (pdf file)

1996

Alexander, J.E., Bauer, L.O., Kuperman, S., Rohrbaugh, J., Morzorati, S., O'Connor, S.J., Porjesz, B., Begleiter, H., and Polich, J. (1996).
Hemispheric differences for P300 amplitude from an auditory oddball task.
International Journal of Psychophysiology 21:189-196. (pdf file)

Begleiter, H. (1996).
The Collaborative Study on the Genetics of Alcoholism: Overview
Alcohol Health & Research World 19:228-236. (pdf file)

Begleiter, H. (1996).
A genomic survey of alcohol dependence and related phenotypes: Results from the collaborative study on the genetics of alcoholism (COGA).
Alcoholism: Clinical and Experimental Research 20:133A-137A. (pdf file)

Begleiter H. Genetics of Alchoholis - An International Perspective (Symposium Summary). Alcohol Clin Exp Res 1996; 20(8):78A-81A.

Bierut L. Female Alchoholism: New Perspectives-Findings from the COGA Study (Symposium Summary). Alcohol Clin Exp Res 1996; Suppl 20(8):168A-171A.

Bucholz K. Female Alchoholism: New Perspectives-Findings from the COGA Study (Symposium Summary). Alcohol Clin Exp Res 1996; Suppl 20(8):168A-171A.

Bucholz K, Heath A, Reich T, Hesselbrock V, Kramer J, Nurnberger Jr. J, Schuckit M. Can We Subtype Alcoholism? A Latent Class Analysis of Data from Relatives of Alcoholics in a Multi-Center Family Study of Alcoholism. Alcohol Clin Exp Res 1996; 20(8):1462-1471.

Cloninger CR. A Genomic Survey of Alcohol Dependence and Related Phenotypes: Results from the Collaborative Study on the Genetics of Alcoholism (COGA). Alcohol Clin Exp Res 1996; 20(8):133A-137A.

Cohen, H.L., Porjesz, B., and Begleiter, H. (1996).
Temporal recovery of auditory evoked potentials in individuals at risk for alcoholism.
Alcohol 13:333-339. (pdf file)

Easton C, Bauer L. Neuropsychological Correlates of Urine Toxicology Results. Prog Neuropsychopharmacol Biol Psychiatry 1996; 20:969-982.

Edenberg H. A Genomic Survey of Alcohol Dependence and Related Phenotypes: Results from the Collaborative Study on the Genetics of Alcoholism (COGA). Alcohol Clin Exp Res 1996; Suppl 20(8):133A-137A.

Hesselbrock V. Female Alcoholism: New Perspectives-Findings from the COGA Study (Symposium Summary). Alcohol Clin Exp Res 1996; Suppl 20(8):168A-171A.

Nurnberger Jr. J. Female Alcoholism: New Perspectives-Findings from the COGA Study (Symposium Summary). Alcohol Clin Exp Res 1996; Suppl 20(8):168A-171A.

Porjesz, B. and Begleiter, H. (1996).
The Collaborative Study on the Genetics of Alcoholism: Neurophysiological component
Alcohol Health & Research World 19:228-236. (pdf file)

Quaid K, Dinwiddie S, Conneally P, Nurnberger Jr. J. Issues in Genetic Testing for Susceptibility to Alcoholism: Lessons from Alzheimer's Disease and Huntington's Disease. Alcoholism 1996; 20(8):1430-1437.

Ramachandran, G., Porjesz, B., Begleiter, H., and Litke, A. (1996).
A simple auditory oddball task in young adult males at high risk for alcoholism.
Alcoholism: Clinical and Experimental Research 20:9-15. (pdf file)

Reich T. A Genomic Survey of Alcohol Dependence and Related Phenotypes: Results from the Collaborative Study on the Genetics of Alcoholism (COGA). Alcohol Clin Exp Res 1996; Suppl 20(8):133A-137A.

Schuckit M. Female Alcoholism: New Perspectives-Findings from the COGA Study (Symposium Summary). Alcohol Clin Exp Res 1996; Suppl 20(8):168A-171A.

Schuckit M, Tipp J, Anthenelli R, Bucholz K, Hesselbrock V, Nurnberger Jr. J. Anorexia Nervosa and Bulimia Nervosa in Alcohol-Dependent Men and Women and Their Relatives. Am J Psychiatry 1996; 153(1):74-82. Download PDF (abstract only)

Schuckit M, Tipp J, Smith T, Wiesbeck G, Kalmijn J. The Relationship Between Self-Rating of the Effects (SRE) of Alcohol and Alcohol Challenge Results in 98 Young Men. J Stud Alcohol 1996; 58:397-404.

Schuckit M, Tsuang J, Anthenelli R, Tipp J, Nurnberger Jr. J. Alcohol Challenges in Young Men from Alcoholic Pedigrees and Control Families: A Report from the COGA Project. J Stud Alcohol 1996; 57:368-377.

Wiesbeck G, Schuckit M, Kalmijn J, Tipp J, Bucholz K, Smith T. An Evaluation of the History of Marijuana Withdrawal Syndrome in a Large Population. Addiction 1996; 91(10):1469-1478. (pdf file)

1995

Alexander, J.E., Porjesz, B., Bauer, L.O., Kuperman, S., Morzorati, S., O'Connor, S.J., Rohrbaugh, J., Begleiter, H., and Polich, J. (1995).
P300 hemispheric amplitude asymmetries from a visual oddball task.
Psychophysiology 32:467-475. (pdf file)

Begleiter, H., Porjesz, B., and Wang, W. (1995).
Event-related brain potentials differentiate priming and recognition to familiar and unfamiliar faces.
Electroencephalography and Clinical Neurophysiology 94:41-49. (pdf file)

Begleiter, H., Reich, T., Hesselbrock, V.M., Porjesz, B., Li, T.K., Schuckit, M.A., Edenberg, H.J., and Rice, J.P. (1995).
The Collaborative Study on the Genetics of Alcoholism.
Alcohol Health & Research World 19:228-236. (pdf file)

Bucholz K, Hesselbrock V, Shayka J, Nurnberger Jr. J, Schuckit M, Schmidt I, Reich T. (1995).

Reliability of Individual Diagnostic Criterion Items for Psychoactive Substance Dependence and the Impact on Diagnosis.

J Stud Alcohol 1995; 56:500-505.

Chorlian, D.B., Porjesz, B., and Cohen, H.L. (1995).
Measuring electrical activity of the brain: ERP mapping in alcohol research.
Alcohol Health & Research World 19:315-320. (pdf file)

Cohen, H.L., Wang, W., Porjesz, B., and Begleiter, H. (1995).
Auditory P300 in young alcoholics: regional response characteristics.
Alcoholism: Clinical and Experimental Research 19:469-475. (pdf file)

Edenberg H, Foroud T, Goate A, Rice J. (1995).

Microsatellite Allele Frequencies and Heterozygosites in a Large Set of Caucasian, Non-Hispanics in the United States.

Am J Hum Genet 1995; Suppl 57:323A.

Koller DL, Foroud T, Conneally PM, Reed T, Edenberg HJ, Li T-K. Linkage Analysis of the MNS and Esterase D Chromosomal Regions with Alcohol Dependence. Am J Hum Genet 1995; Suppl 57:324A.

Kuperman, S., Porjesz, B., Arndt, S., Bauer, L., Begleiter, H., Cizadlo, T., O'Connor, S., and Rohrbaugh, J. (1995).
Multi-center N400 ERP consistency using a primed and unprimed word paradigm.
Electroencephalography and Clinical Neurophysiology 94:462-470. (pdf file)

Porjesz, B., and Begleiter, H. (1995).
Event-related potentials and cognitive function in alcoholism.
Alcohol Health and Research World 19:108-112. (pdf file)

Porjesz B, Begleiter H. Overview: Neurophysiological Component of the COGA National Project. Alcohol Health Res World 1995; 19(3):228-236.

Rice J, Neuman R, Hoshaw S, Daw EW, Gu C. (1995).

TDT With Covariates and Genomic Screens With MOD Scores: Their Behavior on Simulated Data.

Genet Epidemiol 1995; 12:659-664. (pdf file)

Rice, J.P., Reich, T., Bucholz, K.K., Neuman, R.J., Fishman, R., Rochberg, N., Hesselbrock, V.M., Nurnberger, J.I., Jr., Schuckit, M.A., and Begleiter, H. (1995).
Comparison of direct interview and family history diagnoses of alcohol dependence.
Alcoholism: Clinical and Experimental Research 19:1018-1023. (pdf file)

Schuckit M, Anthenelli R, Bucholz K, Hesselbrock V, Tipp J. (1995).

The Time Course of Development of Alcohol-Related Problems in Men and Women.

J Stud Alcohol 1995; 56:218-225. (pdf file)

Schuckit M, Hesselbrock V, Tipp J, Nurnberger Jr. J, Anthenelli R, Crowe R. (1995).

Prevalence of Major Anxiety Disorder in Relatives of Alcohol Dependent Men and Women.

J Stud Alcohol 1995; 56:309-317. (pdf file)

Schuckit M, Tipp J, Reich T, Hesselbrock V, Bucholz K. The Histories of Withdrawal Convulsions and Delirium Tremors in 1,648 Alcohol Dependent Subjects. Addiction 1995; 90:1335-1347. (pdf file)

Schuckit M, Tipp J, Smith T, Shapiro E, Hesselbrock V, Bucholz K, Reich T, Nurnberger Jr. J. An Evaluation of Type A and B Alcoholics. Addiction 1995; 90:1189-1203. (pdf file)

Volkow, N.D., Wang, G.J., Begleiter, H., Hitzemann, R., Pappas, N., Burr, G., Pascani, K., Wong, C., Fowler, J.S., and Wolf, A.P. (1995).
Regional brain metabolic response to Lorazepam in subjects at risk for alcoholism.
Alcoholism: Clinical and Experimental Research 19:510-516. (pdf file)

Zhang, X.L., Begleiter, H., Porjesz, B., Wang, W., and Litke, A. (1995).
Event related potentials during object recognition tasks.
Brain Research Bulletin 38:531-538. (pdf file)

1994

Alexander, J.E., Polich, J., Bloom, F.E., Bauer, L.O., Kuperman, S., Rohrbaugh, J., Morzorati, S., O'Connor, S.J., Porjesz, B., and Begleiter, H. (1994).
P300 from an auditory oddball task: inter-laboratory consistency.
International Journal of Psychophysiology 17:35-46. (pdf file)

Bucholz K, Cadoret R, Cloninger CR, Dinwiddie SH, Hesselbrock V, Nurnberger Jr. J, Reich T, Schmidt I, Schuckit M. A New Semi-Structured Psychiatric Interview for Use in Genetic Linkage Studies: A Report on the Reliability of the SSAGA. J Stud Alcohol 1994; 55:149-158. (pdf file)

Cohen, H.L., Wang, W., Porjesz, B., Bauer, L., Kuperman, S., O'Connor, S.J., Rohrbaugh, J., and Begleiter, H. (1994).
Visual P300: an interlaboratory consistency study.
Alcohol 11:583-587. (pdf file)

Hertz, S., Porjesz, B., Begleiter, H., and Chorlian, D. (1994).
Event-related potentials to faces: the effects of priming and recognition.
Electroencephalography and Clinical Neurophysiology 92:342-351. (pdf file)

Schuckit M, Hesselbrock V. Alcohol Dependence and Anxiety Disorders: What is the Relationship. Am J Psychiatry 1994; 151:1723-1734. (pdf file)

Schuckit M, Hesselbrock V, Tipp J, Anthenelli R, Bucholz K, Radziminski S. A Comparison of DSM-III-R, and ICD-10 Substance Use Disorders Diagnoses in 1922 Men and Women Subjects in the COGA Study. Addiction 1994; 89:1629-1638. (pdf file)

Schuckit M, Tipp J, Kelner E. Are Daughters of Alcoholics More Likely to Marry Alcoholics? Am J Drug Alcohol Abuse 1994; 20(2):237-245. (pdf file)

Wang, W., Begleiter, H., and Porjesz, B. (1994).
Surface energy, its density and distance: new measures with application to human cerebral potentials.
Brain Topography 6:193-202. (pdf file)

Wang, W., Begleiter, H., and Porjesz, B. (1994).
Multivariate composite estimators: new ways to track signals with application to human cerebral potentials.
Brain Topography 7:9-15. (pdf file)

Wang, W., Begleiter, H., and Porjesz, B. (1994).
Localization of multiple dipole sources of human cerebral potential based on scd and a model selection criterion.
Proceedings of the Section of Statistics in Epidemiology of the American Statistical Association 217-222. (pdf file)

1993

Cohen, H.L., Porjesz, B., and Begleiter, H. (1993).
Ethanol-induced alterations in electroencephalographic activity in adult males.
Neuropsychopharmacology 8:365-370. (pdf file)

Cohen, H.L., Porjesz, B., and Begleiter, H. (1993).
The effects of ethanol on EEG activity in males at risk for alcoholism.
Electroencephalography and Clinical Neurophysiology 86:368-376. (pdf file)

Realmuto, G., Begleiter, H., Odencrantz, J., and Porjesz, B. (1993).
Event-related potential evidence of dysfunction in automatic processing in abstinent alcoholics.
Biological Psychiatry 33:594-601. (pdf file)

1992

Twitchell G, Hertzog C, Klein J, Schuckit M. Anatomy of a Follow-Up. British J Alcohol 1992; 87:1327-1333.

Zaninelli, R.M., Porjesz, B., and Begleiter, H. (1992).
The Tridimensional Personality Questionnaire in males at high and low risk for alcoholism.
Alcoholism: Clinical and Experimental Research 16:68-70. (pdf file)

 

1991

Cohen, H.L., Porjesz, B., and Begleiter, H. (1991).
EEG characteristics in males at risk for alcoholism.
Alcoholism: Clinical and Experimental Research 15:858-861. (pdf file)

1990

Begleiter, H. and Porjesz, B. (1990).
Event-related potentials in populations at risk for alcoholism.
Electroencephalography and Clinical Neurophysiology Supplement 41:177-182. (pdf file)

Begleiter, H. and Porjesz, B. (1990).
Neuroelectric processes in individuals at risk for alcoholism.
Alcohol and Alcoholism 25:251-256. (pdf file)

Porjesz, B. and Begleiter, H. (1990).
Event-related potentials in individuals at risk for alcoholism.
Alcohol 7:465-469. (pdf file)

Rice J. The Use of Computer Simulation in Genetic Linkage Studies. Alcohol Health Res World 1990; 14(3):253-257. (pdf file)