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Collaborative Study on the Genetics of Alcoholism

 

Reviewed articles with supplied COGA data (SAGE articles are marked with ***)

 A complete list of a all publications with downloaded COGA data as a pdf-file (last change 2014-03-31).

2014

*** Cao, J., Liu, X., Han, S., Zhang, C.K., Liu, Z., and Li, D. (2014).
Association of the HTR2A gene with alcohol and heroin abuse.
Human Genetics 133(3):357-365. PMID: 24178752. (pdf file)

Hsieh, T.-J., Chang, S.-H., and Tai, J.J. (2014).
A family-based robust multivariate association test using maximum statistic.
Annals of Human Genetics 78(2):117-128. PMID: 24571230.
(pdf file)

*** Taylor, A. and Wang, K.S. (2014)
Association between DPYSL2 gene polymorphisms and alcohol dependence in Caucasian samples.
Journal of Neural Transmission 121(1):105-111. PMID: 23846846. (pdf file)

2013

*** Belsky, D.W., Moffitt, T.E., Baker, T.B., Biddle, A.K., Evans, J.P., Harrington, H., Houts, R., Meier, M., Sugden, K., Williams, B., Poulton, R., and Caspi, A. (2013)
Polygenic risk and the developmental progression to heavy, persistent smoking and nicotine dependence: evidence from a 4-decade longitudinal study.
JAMA Psychiatry 70(5):534-542 PMID: 23536134 (pdf file)

*** Blaine, S., Claus, E., Harlaar, N., and Hutchison, K. (2013).
TACR1 genotypes predict fMRI response to alcohol cues and level of alcohol dependence.
Alcoholism: Clinical and Experimental Research 37(Suppl 1):E125-130. PMID: 23078527 (pdf-file)

*** Cui WY, Wang S, Yang J, Yi SG, Yoon D, Kim YJ, Payne TJ, Ma JZ, Park T, Li MD. (2013).
Significant association of CHRNB3 variants with nicotine dependence in multiple ethnic populations.
Molecular Psychiatry 18:1149-1151 PMID: 23319001 (pdf file)

*** Du, M., Prescott, J., Cornelis, M.C., Hankinson, S.E., Giovannucci, E., Kraft, P., and De Vivo, I. (2013)
Genetic predisposition to higher body mass index or type 2 diabetes and leukocyte telomere length in the Nurses' Health Study.
PLoS One 8(2):e52240. PMID: 23424613 (pdf file)

*** Guo, X., Liu, Z., Wang, X., and Zhang, H. (2013).
Genetic association test for multiple traits at gene level.
Genetic Epidemiology 37(1):122-129. PMID: 23032486 (pdf file)

Han, S., Yang, B.-Z., Kranzler, H.R., Liu, X., Zhao, H., Farrer, L.A., Boerwinkle, E., Potash, J.B., and Gelernter, J. (2013)
Integrating GWASs and human protein interaction networks identifies a gene subnetwork underlying alcohol dependence
The American Journal of Human Genetics 93(6):1027-1034. PMID: 24268660 (pdf file)

*** Liu, Z., Guo, X., Jiang, Y., and Zhang, H. (2013).
NCK2 Is significantly associated with opiates addiction in african-origin men.
The Scientific World Journal 2013:748979. PMID: 23533358 (pdf file)

*** Pan, Y., Pan, Y., Luo, X., Liu, X., Wu, L.Y., Zhang, Q., Wang, L., Wang, W., Zuo, L., and Wang, K.S. (2013).
Genome-wide association studies of maximum number of drinks.
Journal of Psychiatric Research 47(11):1717-1724. PMID: 23953852 (pdf file)

*** Pan, Y., Wang, K.-S., Wang, L., and Wu, L.Y. (2013).
Common variants in HLA-DRA gene are associated with alcohol dependence in two caucasian samples.
Journal of Molecular Neuroscience 49(3):574-581. PMID: 22890421 (pdf file)

*** Ray, L.A., Sehl, M., Bujarski, S., Hutchison, K., Blaine, S., and Enoch, M.A. (2013).
The CRHR1 gene, trauma exposure, and alcoholism risk: a test of G × E effects.
Genes, Brain and Behavior 12(4):361-369. PMID: 23473364
(pdf file)

*** Wang, L., Liu, X., Luo, X., Zeng, M., Zuo, L., and Wang, K.-S. (2013)
Genetic Variants in the Fat Mass- and Obesity-Associated (FTO) Gene are Associated with Alcohol Dependence.
Journal of Molecular Neuroscience 51(2):416-424. PMID: 23771786 (pdf file)


*** Wen, Y, Schaid, D.J., and Lu, Q. (2013).
A bivariate Mann-Whitney approach for unraveling genetic variants and interactions contributing to comorbidity.
Genetic Epidemiology 37(3):248-255. PMID: 23334941. (pdf file)

*** Zuo, L.J., Saba, L., Wang, K.S., Zhang, X.Y., Krystal, J.H., Tabakoff, B., and Luo, X.G. (2013)
Exome-Wide Association Study of Replicable Nonsynonymous Variants Conferring Risk for Alcohol Dependence
Journal of Studies on Alcohol and Drugs 74(4):622-625. PMID: 23739027. (pdf file)

*** Zuo, L., Wang, K., Zhang, X.Y., Krystal, J.H., Li, C.S., Zhang, F., Zhang, H., and Luo, X. (2013)
NKAIN1-SERINC2 is a functional, replicable and genome-wide significant risk gene region specific for alcohol dependence in subjects of European descent.
Drug and Alcohol Dependence 129(3):254-264. PMID: 23455491 (pdf file)

*** Zuo, L., Wang, K.S., Zhang, X.Y., Li, C.S., Zhang, F., Wang, X., Chen, W., Gao, G., Zhang, H., Krystal, J.H., and Luo, X. (2013)
Rare SERINC2 variants are specific for alcohol dependence in individuals of European descent.
Pharmacogenetics and Genomics 23(8):395-402. PMID: 23778322 (pdf file)

*** Zuo, L., Wang, K., Zhang, X., Pan, X., Wang, G., Krystal, J.H., Zhang, H., and Luo, X. (2013)
Sex chromosome-wide association analysis suggested male-specific risk genes for alcohol dependence.
Psychiatric Genetics 23(6):233-238 PMID: 23907288 (pdf file)

*** Zuo, L., Wang, K., Zhang, X.Y., Pan, X., Wang, G., Tan, Y., Zhong, C., Krystal, J.H., State, M., Zhang, H., and Luo, X. (2013).
Association between common alcohol dehydrogenase gene (ADH) variants and schizophrenia and autism.
Human Genetics 132(7):735-743 PMID: 23468174 (pdf file)

*** Zuo, L., Zhang, H., Malison, R.T., Li, C.S., Zhang, X.Y., Wang, F., Lu, L., Lu, L., Wang, X., Krystal, J.H., Zhang, F., Deng, H.W., and Luo, X. (2013).
Rare ADH variant constellations are specific for alcohol dependence.
Alcohol and Alcoholism 48(1):9-14. PMID: 23019235 (pdf file)

*** Zuo, L., Zhang, X.Y., Wang, F., Li, C.S., Lu, L., Ye, L., Zhang, H., Krystal, J.H., Deng, H.W., and Luo X. (2013).
Genome-wide significant association signals in IPO11-HTR1A region specific for alcohol and nicotine dependence.
Alcoholism: Clinical and Experimental Research 37(5):730-739 PMID: 23216389 (pdf file)


2012

Fang, Y.H. and Chiu, Y.F. (2012).
SVM-based generalized multifactor dimensionality reduction approaches for detecting gene-gene interactions in family studies.
Genetic Epidemiology 36(2):88-98. PMID: 2285147.

*** Frank, J., Cichon, S., Treutlein, J., Ridinger, M., Mattheisen, M., Hoffmann, P., Herms, S., Wodarz, N., Soyka, M., Zill, P., Maier, W., Mössner, R., Gaebel, W., Dahmen, N., Scherbaum, N., Schmäl, C., Steffens, M., Lucae, S., Ising, M., Müller-Myhsok, B., Nöthen, M.M., Mann, K., Kiefer, F., and Rietschel M. (2012).
Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster.
Addiction Biology 17(1):171-180. PMCID: PMC3245349

*** Guo, X., Liu, Z., Wang, X., and Zhang, H. (2012).
Large scale association analysis for drug addiction: results from SNP to gene.
ScientificWorldJournal 2012:939584. PMCID: PMC3543790

*** Han, S., Yang, B.Z., Kranzler, H.R., Oslin, D., Anton, R., Farrer, L.A., and Gelernter, J. (2012).
Linkage analysis followed by association show NRG1 associated with cannabis dependence in African Americans.
Biological Psychiatry 72(8):637-644.

*** Jackson, K.J., Sanjakdar, S.S., Chen, X., and Damaj, M.I. (2012).
Nicotine reward and affective nicotine withdrawal signs are attenuated in calcium/calmodulin-dependent protein kinase IV knockout mice.
PLoS One 7(11):e51154. PMID: 23226481. (pdf file)

Listgarten, J., Lippert, C., Kadie, C.M., Davidson, R.I., Eskin, E., and Heckerman, D. (2012).
Improved linear mixed models for genome-wide association studies.
Nature Methods 9: 525-526.

*** Shirley, M.D., Baugher, J.D., Stevens, E.L., Tang, Z., Gerry, N., Beiswanger, C.M., Berlin, D.S., and Pevsner, J. (2012).
Chromosomal variation in lymphoblastoid cell lines.
Human Mutation 33(7):1075-1086. PMCID: PMC3370055

Thornton, T., Zhang, Q., Cai, X., Ober, C., and McPeek, M.S. (2012).
XM: Association testing on the X chromosome in case-control samples with related individuals.
Genetic Epidemiology 36(5):438-450.

*** Wang, K.S., Liu, X., Aragam, N., Mullersman, J.E., Jian, X., Pan, Y., and Liu, Y. (2012).
Polymorphisms in ABLIM1 are associated with personality traits and alcohol dependence.
Journal of Molecular Neuroscience 46(2):265-271.

*** Wang, K.S., Liu, X., Zhang, Q., Wu, L.Y., and Zeng, M. (2012).
Genome-wide association study identifies 5q21 and 9p24.1 (KDM4C) loci associated with alcohol withdrawal symptoms.
Journal of Neural Transmission 119(4):425-433.

*** Wang, K.S., Liu, X., Zhang, Q., and Zeng, M. (2012).
ANAPC1 and SLCO3A1 are associated with nicotine dependence: Meta-analysis of genome-wide association studies.
Drug Alcohol Depend124(3):325-332.

*** Wang, K.S., Liu, X., Zheng, S., Zeng, M., Pan, Y., and Callahan, K. (2012).
A novel locus for body mass index on 5p15.2: A meta-analysis of two genome-wide association studies.
Gene 500(1):80-84.

Zhu, W., Jiang, Y., and Zhang, H. (2012).
Nonparametric covariate-adjusted association tests based on the generalized Kendall’s Tau.
Journal of the American Statistical Association 107(497):1-11.

*** Zuo, L., Gelernter, J., Zhang, C.K., Zhao, H., Lu, L., Kranzler, H.R., Malison, R.T., Li, C.S., Wang, F., Zhang, X.Y., Deng, H.W., Krystal, J.H., Zhang, F., sand Luo, X. (2012).
Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q.
Neuropsychopharmacology 37(2):557-566. PMCID: PMC3242317

*** Zuo, L., Zhang, F., Zhang, H., Zhang, X.Y., Wang, F., Li, C.S., Lu, L., Hong, J., Lu, L., Krystal, J.H., Deng, H.W., and Luo X. (2012).
Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence.

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 159B(4):437-444. PMCID: PMC3405545

2011

*** Chen, X., Cho, K., Singer, B.H., and Zhang, H. (2011).
The nuclear transcription factor PKNOX2 is a candidate gene for substance dependence in European-origin women.
PLoS One 6(1):e16002.

*** Drgon, T., Johnson, C.A., Nino, M., Drgonova, J., Walther, D.M., and Uhl, G.R. (2011).
“Replicated” genome wide association for dependence on illegal substances: genomic regions identified by overlapping clusters of nominally positive SNPs.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 156:125-138.

Feng, Z., Wong, W., Gao, X., and Schenkel, F. (2011).
Generalized genetic association study with samples of related individuals.
Annals of Applied Statistics 5(3):2019-2030.

Jian, X.Q., Wang, K.S., Wu, T.J., Hillhouse, J.J., and Mullersman, J.E. (2011).
Association of ADAM10 and CAMK2A polymorphisms with conduct disorder: Evidence from family-based studies.
Journal of Abnormal Child Psychology 39(6):773-82.

*** Johnson, C., Drgon, T., Walther, D., and Uhl, G.R. (2011).
Genomic regions identified by overlapping clusters of nominally-positive SNPs from genome-wide studies of alcohol and illegal substance dependence.
PLoS One 6(7):e19210. PMCID: PMC3144872. (pdf file)

Lippert, C., Listgarten, J., Liu, Y., Kadie, C.M., Davidson, R.I., and Heckerman, D. (2011).
FaST linear mixed models for genome-wide association studies.
Nature Methods 8(10):833-835.

Pan, Y., Wang, K.S., and Aragam, N. (2011).
NTM and NR3C2 polymorphisms influencing intelligence: family-based association studies.
Progress in Neuro-Psychopharmacology & Biological Psychiatry 35(1):154-160.

Wang, K.S., Liu, X., Aragam, N., Jian, X., Mullersman, J.E., Liu, Y., and Pan, Y. (2011).
Family-based association analysis of alcohol dependence in the COGA sample and replication in the Australian twin-family study.
Journal of Neural Transmission 118(9): 1293-1299.

Wang, K.S., Liu, X., Zhang, Q., Pan, Y., Aragam, N., and Zeng, M. (2011).
A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.
Journal of Psychiatric Research 45(11):1419-1425.

Wang, Z. (2011).
Direct assessment of multiple testing correction in case-control association studies with related individuals.
Genetic Epidemiology 35(1):70-79.

Zuo, L., Zhang, C.K., Wang, F., Li, C.S., Zhao, H., Lu, L., Zhang, X.Y., Lu, L., Zhang, H., Zhang, F., Krystal, J.H., and Luo, X. (2011).
A novel, functional and replicable risk gene region for alcohol dependence identified by genome-wide association study.
PLoS One 6(11):e26726. PMCID: PMC3210123

2010

Chiu, Y.-F., Chiou, J.-M., Liang, K.-Y., and Lee, C.-Y. (2010).
Incorporation of covariates in simultaneous localization of two linked loci using affected relative pairs.
BMC Genetics 11:67. (pdf file)

Diao, G., and Lin, D.Y. (2010).
Variance-components methods for linkage and association analysis of ordinal traits in general pedigrees.
Genetic Epidemiology 34(3):232-7. PMID: 19918762 (pdf file)

*** Drgon, T., Zhang, P.-W., Johnson, C., Walther, D., Hess, J., Nino, M., and Uhl, G.R. (2010).
Genome wide association for addiction: replicated results and comparisons of two analytic approaches.
PLoS One 5(1):e8832. PMCID: PMC2809089. (pdf file)

Han, S., Gelernter, J., Luo, X., and Yang, B.Z. (2010).
Meta-analysis of 15 genome-wide linkage scans of smoking behavior.
Biological Psychiatry 67(1):12-19. PMID: 19819424 (pdf file)

*** Noor, A., Whibley, A., Marshall, C.R., Gianakopoulos, P.J., Piton, A., Carson, A.R., Orlic-Milacic, M., Lionel, A.C., Sato, D., Pinto, D., Drmic, I., Noakes, C., Senman, L., Zhang, X., Mo, R., Gauthier, J., Crosbie, J., Pagnamenta, A.T., Munson, J., Estes, A.M., Fiebig, A., Franke, A., Schreiber, S., Stewart, A.F., Roberts, R., McPherson, R., Guter, S.J., Cook, E.H., Jr., Dawson, G., Schellenberg, G.D., Battaglia, A., Maestrini, E.; Autism Genome Project Consortium, Jeng, L., Hutchison, T., Rajcan-Separovic, E., Chudley, A.E., Lewis, S.M., Liu, X., Holden, J.J., Fernandez, B., Zwaigenbaum, L., Bryson, S.E., Roberts, W., Szatmari, P., Gallagher, L., Stratton, M.R., Gecz, J., Brady, A.F., Schwartz, C.E., Schachar, R.J., Monaco, A.P., Rouleau, G.A., Hui, C.C., Lucy Raymond, F., Scherer, S.W., and Vincent, J.B. (2010).
Disruption at the PTCHD1 locus on Xp22.11 in autism spectrum disorder and intellectual disability.
Science Translational Medicine 2(49):49ra68. PMCID: PMC2987731. (pdf file)

***Thornton, T. and McPeek, M.S. (2010).
ROADTRIPS: Case-control association testing with partially or completely unknown population and pedigree structure.
American Journal of Human Genetics 86(2):172-84. PMCID: PMC2820184. (pdf file)

Zhang, H., Liu, C.-T., and Wang, X. (2010).
An association test for multiple traits based on the generalized Kendall’s Tau.
Journal of the American Statistical Association 105(490):473-481.PMID: 20711441 (pdf file)

2009

Wang, Z. and McPeek, M.S. (2009).
An incomplete-data quasi-likelihood approach to haplotype-based genetic association studies on related individuals.
Journal of the American Statistical Association 104(487):1251-1260. PMID: 20428335 (pdf file)

2008

Feng, R. and Zhang, H. (2008).
A score test for linkage analysis of ordinal traits based on IBD sharing.
Biostatistics 9(1):114-127.

Feng, R. and Zhang, H. (2008).
A genomic imprinting test for ordinal traits in pedigree data.
Genetic Epidemiology 32(2):132-142.

Ishiguro, H., Gong, J.P., Hall, F.S., Arinami, T., and Uhl, G.R. (2008).
Association of PTPRB gene polymorphism with drug addiction.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 147B(7):1167-1172.

Jacobson, K.C., Beseler, C.L., Lasky-Su, J., Faraone, S.V., Glatt, S.J., Kremen, W.S., Lyons, M.J., and Tsuang, M.T. (2008).
Ordered subsets linkage analysis of antisocial behavior in substance use disorder among participants in the Collaborative Study on the Genetics of Alcoholism.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 147B(7):1258-1269.

Jonasdottir, G., Becker, T., Humphreys, K., and Palmgren, J. (2008).
Testing association in the presence of linkage using the GRE and multiple markers.
Genetic Epidemiology 32(5):425-433.

Kim, Y., Duggal, P., Gillanders, E.M., Kim, H., andBailey-Wilson, J.E. (2008).
Examining the effect of linkage disequilibrium between markers on the Type I error rate and power of nonparametric multipoint linkage analysis of two-generation and multigenerational pedigrees in the presence of missing genotype data.
Genetic Epidemiology 32(1):41-51. PMCID: PMC2216429

Yang, H.C., Hsieh, H.Y., and Fann, C.S. (2008).
Kernel-based association test.
Genetics 179(2):1057-1068. PMCID: PMC2429859 (pdf file)

2007

Dietter,. J., Mattheisen, M., Fürst, R., Rüschendorf, F., Wienker, T.F., and Strauch, K. (2007).
Linkage analysis using sex-specific recombination fractions with GENEHUNTER-MODSCORE
Bioinformatics 23(1):64-70.

Ducci, F., Enoch, M.A., Funt, S., Virkkunen, M., Albaugh, B., and Goldman, D. (2007).
Increased anxiety and other similarities in temperament of alcoholics with and without antisocial personality disorder across three diverse populations.
Alcohol 41(1):3-12.

Ishiguro, H., Walther, D., Arinami, T., and Uhl, G.R. (2007).
Variation in a bicarbonate co-transporter gene family member SLC4A7 is associated with propensity to addictions: a study using fine-mapping and three samples.
Addiction 102(8):1320-1325.

Thornton, T. and McPeek, M.S. (2007).
Case-control association test with related individuals: A more powerful quasi-likelihood Score test.
American Journal of Human Genetics 81(2):321-337. PMCID: PMC1950805 (pdf file)

2006

Diao, G. and Lin, D.Y. (2006).
Improving the power of association tests for quantitative traits in family studies.
Genetic Epidemiology 30:301-313.

Diao,. G. and Lin, D.Y. (2006).
Semiparametic variance-component models for linkage and association analyses of censored trait data.
Genetic Epidemiology 30:570-581.

Wang, X., Ye, Y., and Zhang, H. (2006).
Family-based association tests for ordinal traits adjusting for covariates.
Genetic Epidemiology 30(8):728-736.

Zhang, H., Wang, X., and Ye, Y. (2006).
Detection of genes for ordinal traits in nuclear families and a unified approach for association studies.
Genetics 172(1):693-699. (pdf file)

1999

Sheffield, L.J., Knauert, M.P., Pakstis, A.J., Zhao, H., and Kidd, K.K. (1999)
Analyses of the COGA data set in one ethnic group with examinations of alternative definitions of alcoholism
Genetic Epidemiology 17(Suppl 1):S319-324. PMID: 10597456