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PROCESS – (NIH)
EEG in the ED – (NIH)
Hyaluronidase – (Baxter)
Research Fellow – (ECRIP: Empire Clinical Research Investigator Program)
Society for Airway Management
•Tsang K, Sinert RH, Li J. Tuberculosis. eMedicine from WebMD. Updated November 05, 2010.
•Brandler ES, Sinert RH. Shock, Cardiogenic. eMedicine from WebMD. Updated January 26, 2010.
•Aherne A, Sinert RH. Glaucoma, Acute Angle-Closure. eMedicine from WebMD. Updated November 10, 2010.
Please continue to welcome our research students/ Academic Associates to the clinical area. They are invaluable to the success of our projects, so please make them feel welcome and provide them with any assistance they may need in identifying patients who are eligible for our studies. The research students have expressed that the residents have been very helpful in identifying patients, teaching them, and making them feel at home. Thank you very much!
Several new studies will be starting soon and we need help from the residents.
1. Platelet-Oriented Inhibition in New TIA and minor ischemic stroke
(POINT) Trial (NIH)
To determine whether clopidogrel 75 mg/day by mouth after a loading dose of 600 mg of clopidogrel is effective in preventing major ischemic vascular events (ischemic stroke, myocardial infarction, and ischemic vascular death) at 90 days when initiated within 12 hours of TIA or minor ischemic stroke onset in patients receiving aspirin 50-325 mg/day (with a dose of 162 mg daily for 5 days followed by 81 mg daily strongly recommended). Drs. Chatterjee, Sinert, Backster
2. Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH)-II (NIH)
To determine the therapeutic benefit of intensive SBP treatment (SBP<140 mmHg) compared with standard SBP treatment (SBP<180 mmHg) in reducing the proportion of patients with death and disability (mRS of 4-6) at Day 90 among subjects with ICH treated within 3 hours of symptom onset. Drs. Brandler, Sinert
3. Potential of rtPA for Ischemic Strokes with Mild Symptoms (PRISMS) Trial
To definitively determine the efficacy of IV rtPA treatment of ischemic strokes with mild deficits (defined as NIH
Stroke Scale [NIHSS] score ≤5 and not clearly disabling) within 4.5 hours of onset. Drs. Chatterjee, Sinert
4. Angioneurotic Edema
a) Descriptive study - Prevalence, association with medications and outcomes of angioneurotic edema in our ED
b) Investigative Study - What is the percentage of patients we diagnose with angioneurotic edema who really have hereditary angioedema
c) Experimental Study - Ecallantide for ACEI-induced angioedema (NIH) Drs. Paladino, Sinert
Patients to enroll in research studies
Writing an eMedicine chapter is a great way to learn a subject, buff your CV and earn points toward satisfying your academic requirement. Topic availability changes frequently, so just ask any of the faculty mentors or the research division if you are interested in participating in this highly rewarding endeavor…
eMedicine Chapter faculty mentors include: Sinert, Paladino, Doty, Silverberg, Gleyzer (ID), Peacock, Erogul, Agoritsas (Peds) & Weiner (Tox), Quinn (sports Med / Ortho)
Animal Lab Projects
Be sure to “link records to institution”
A Quick Look at
Current Active Projects
All attendings & residents are required to complete certification for “Human Participants Protection Education.” Please sign on to the CITI (Collaborative IRB Training Initiative) training program below:
You must speak to Dr. Zehtabchi or Dr. Laoteppitaks one month prior to your rotations.
The goal of the rotation is a published pubMed Indexed manuscript. Depending on experience, available options include: Visual Diagnosis, Brief Report, Case Report, Review, or you may assist with one of the ongoing Original Research Projects.
During your rotation, join us at the research meeting on Wednesday afternoons in Dr. Sinert’s office at 12 PM.
Policy: Conference Reimbursement
For abstract presenters, our Department will reimburse you for your hotel and meeting registration. This applies to both residents and attendings, and is in addition to your CME money. Due to the new changes in department reimbursement policy, you need to contact Ms. Patella before paying for your registration, or booking your hotel or transportation. Please refer to the department website (under Research) for details on how to obtain reimbursement.
An "author" is generally considered to be someone who has made substantive intellectual contributions to a published study, and biomedical authorship continues to have important academic, social, and financial implications. (1) In the past, readers were rarely provided with information about contributions to studies from those listed as authors and in acknowledgments. (2) Some journals now request and publish information about the contributions of each person named as having participated in a submitted study, at least for original research. Editors are strongly encouraged to develop and implement a contributorship policy, as well as a policy on identifying who is responsible for the integrity of the work as a whole.
While contributorship and guarantorship policies obviously remove much of the ambiguity surrounding contributions, it leaves unresolved the question of the quantity and quality of contribution that qualify for authorship. The International Committee of Medical Journal Editors has recommended the following criteria for authorship; these criteria are still appropriate for those journals that distinguish authors from other contributors.
Some journals now also request that one or more authors, referred to as "guarantors," be identified as the persons who take responsibility for the integrity of the work as a whole, from inception to published article, and publish that information. .
The order of authorship on the byline should be a joint decision of the co-authors. Authors should be prepared to explain the order in which authors are listed. For further information on this and other policies visit http://www.icmje.org
Get Involved in Research!!
All faculty and residents are part of the Research Committee. On the first Wednesday of every month, ongoing projects are reviewed and new research is discussed. All Residents must contact Dr. Zehtabchi & Dr. Laoteppitaks at least one month prior to the start of your Research Rotation to setup a project. If you fail to do this your research time will be converted into clinical shifts. Everyone is encouraged to participate in at least one study (regardless of your PGY level) throughout the academic year.
Feel free to contact the Research Division:
Dr. Savitri Singh
Every Wednesday Dr. Sinert will be available in his office (10 am to 4 pm) to meet with faculty and residents on research issues. Just contact Dr. Sinert one week in advance to setup a time