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Department of Cell Biology Faculty
Olcay Batuman, M.D.*
Professor of Medicine and Cell Biology
Dept. of Medicine, Div. of Hematology & Dept. of Cell Biology, Box 20
Multiple Myeloma Research at SUNY Downstate Medical Center
Our Research Focus
Genome-wide comparison of endothelial cells and tumor cells in patients with multiple myeloma, the second most common hematologic malignancy in the US. Ongoing studies also focus on the elucidation and characterization of multiple myeloma progenitor/stem cells, with the aim of targeting this population for improved patient survival.
SUNY Downstate Vascular Stem Cell Genome Consortium (11/1/08 - 4/30/10)
MBCCOP CA-114671 (9/1/07 - 5/31/10)
Sadeaqua Scott, Ph.D. Graduate Student, Molecular and Cell Biology — 2006-Present
Dr. Marc Braunstein, M.D. - Ph.D. Program — 2004-2009
Dr. Orhan Akman, Molecular and Cell Biology — 1998-2002
Selected Peer-reviewed Publications
On this site you will find raw genomic data (Affymetrix gene expression and Agilent comparative genomic hybridization microarray data) analyzed for the manuscript entitled, "Genome-wide profiling of endothelial progenitor cells in multiple myeloma: disease-relevant pathways and tumor endothelial markers." The files are WinZip compressed. If you do not already have WinZip installed, the free version of it is available at http://www.winzip.com.
Agilent Human Genome Array Comparative Genomic Hybridization (aCGH) Microarray - 988MB: .txt files for paired bone marrow endothelial progenitor cell and tumor cell samples from 16 newly-diagnosed myeloma patients.
Affymetrix GeneChip U133 Plus 2.0 microarrays - 147MB: .cel files for bone marrow endothelial progenitor cells from 20 newly-diagnosed myeloma patients, and corresponding tumor cell data from 10 of these patients.
* Holds primary appointment in other department.