Department of Biochemistry
– DRUG DELIVERY
– PAIN PERCEPTION
||A mouse carrying a mutation in the gene leading to muscular dystrophy in humans was treated with protease inhibitors. The dystrophic muscle partially regains the appearance of normal muscle as shown in tissue sections stained with hematoxylin and eosin.
Upper left: muscle from a normal mouse,
Upper Right: muscle from a dystrophic mouse,
Lower Left: muscle from a dystrophic mouse treated with protease inhibitors
The Biochemistry Department has a two-fold mission: research and education. Researchers, sponsored by National Institutes of Health, American Cancer Society, and American Heart Association as well as private agencies study a diverse array of biological issues, from protein structure and function to cancer to pain perception to nutrition. Insights gained from the research enterprise help bring the latest developments in biochemistry, molecular biology, and molecular genetics to medical students.
The Biochemistry Department participates in both the molecular and cellular biology and neuroscience graduate program. The department conducts the graduate biochemistry course and contributes to the teaching of the molecular and cellular biology course required of all students in the program. The Biochemistry Department is also the home of the Protein Structure Laboratory and the PhosphorImager User Center.
The Protein Structure Laboratory is equipped for Mass Spectrometry, N-terminal sequencing of proteins and Reverse-Phase HPLC. The PhosphorImager detects and quantitates radioactive and fluorescent signals in situ.