Research Projects
- Role of the Haymaker gene in malignant diseases.
- Role of Haymaker and its cognate receptor in Natural Killer lymphocyte mediated cytotoxicity of tumor cells.
- Role of grp94 in cell mediated cytotoxicity
- Diagnosis of allograft rejection using molecular probes of lymphocyte activation markers.
Laboratory Members:
- Ballabh Das, Research Associate Professor
- Shi Zhen Tao, Sr research Associate
- Rimma Mushnitsky, Sr. Technologist
- Robyn Smolkin, Ph.D. candidate
- Mark Bluth, Graduate student
SELECTED RECENT PUBLICATIONS
Das, B., Mondragon, M., Tao, S-Z., and Norin, A.J. Preferential interaction of a novel tumor surface protein (p38.5) with with a receptor on naive NK cells. J. Exp.Med. 185: 1735-1742, 1997.
Kamholz, S.L., Brewer, R.J., Grujalva, G, Burack, J., Del Rio, M.J., Vaynblatt, M., Lawson, N., Squinto, S., Fodor, W.L., and Norin, A.J. Laboratory Studies in Cross-Species Lung Transplantation. World J. Surg. 21:951 - 955, 1997.
Towle, M., Mondragon-Escorpizo, M., Norin, Allen J. and Fukada, K. Deprivation of Leukemia Inhibitory Factor by its Function-Blocking Antibodies Augments T. Cell Activation. Journal of Interferon and Cytokine Research 18:387-392, 1998.
Norin, A.J., Brewer, R.J., Liu, Q., Del Rio, M.J., Burack, J., and Kamholz, S.L. Donor-Antigen Independent Effector Mechanisms of Graft Rejection: A Novel Cell Surface Target of IL-2 Activated Lymphocytes. Trans. Proc.31: 787, 1999.
Bergamini, L., Mondragon-Escorpizo, M.O., Hong, J., Norin, A. Does a Weak Anti-Creg Antibody Predict Accelerated Antibody Mediated Rejection on Retransplantation? Human Immunology 60: S96, 1999.
Sobocka, M. B., Sobocki, T., Banerjee, P.l, Weiss, C., Rushbrook, J. I., Norin, A., Hartwig, J., Salifu, Moro O., Markell, M. S., Babinska, A., Ehrlich, Y. H., Kornecki, E. Human Platelet F11 Receptor is a Cell Adhesion Molecule Member of the Ig Superfamily Involved in Platelet Aggregation. Blood 95: 2600 - 2609, 2000.
Switzer, W.M., Michler R.,Shanmugam V., Matthews, A., Hussain, A., Bhullar V., Wright, A., Sandstrom, P., Chapmam L.E., Weber C., Safley S., Danny R, Navarro A, Evans, V, Norin A., Kwiatkowski, P, Heneine W. Lack of cross-species transmission of porcine endogenous retrovirus infection to nonhuman primate recipients of porcine cells, tissues, or organs. Transplantation 71: 959-965, 2001.
Das, B., Tao, Shi-Zhen, Mushnitsky, R and Norin, A.J. Genetic identity and expression of p38.5 ( Haymaker) in human malignant and non-malignant cells. Int J Cancer, (In press).